The article considers the peculiarities of the structure and functioning of distribution electric power networks of Ukraine. A list of technical and organisational measures has been determined, which, both at the design and operation stages, provide for the possibility of using modern technical means and control technologies to ensure regulatory requirements for the parameters of modes, indicators of the quality of electricity and reliability of electricity supply to consumers, and are the most appropriate for improving the efficiency of distribution electric networks. The paper proposes a criterion for optimising the modes of distribution electric networks, which takes into account the nature of load changes, peculiarities of voltage regulation and reactive power compensation in electric networks, as well as the availability of sources of distributed generation and energy storage systems in the network, and additionally provides for the possibility of analysing the operating conditions of generation devices and power equipment. For the studied 10 kV electrical networks, measures have been developed to ensure the conditions for optimising operating modes with regard to these factors. A description of the proposed algorithm for selecting the most appropriate of the developed measures is given, which takes into account the current situation in the electricity market, general global trends in the development of distribution electric networks, current trends and prospects for the development of technical means of ensuring the parameters of the mode of electric networks, automation systems and intelligent control systems for the modes of the studied electric networks, as well as indicators of power supply reliability and quality of electricity supply services to consumers.