Introduction. The paper represents a conceptual framework based on state support for innovative development of the national economy. The main directions of state institutional support and stimulation of innovations in the national macroe-conomic environment are determined. The main components of innovation in the national macroeconomic environment are identified. The purpose of the article is to form a conceptual basis for state support for innovative development of the national economy. Results. It is proved that the main factor of sustainable financial and economic development of the national economy in the conditions of transformation is scientific and technical progress. It was found out that the stimulation and provision of innovation and investment activity in the development of scientific and technological potential in the macroeconomic envi-ronment of the country is the main mission of state support for innovative development of the national economy. It is out-lined that the reproduction of knowledge is the basis of the innovation economy, which is impossible without an effective and efficient system of knowledge accumulation and their practical application, which, in turn, aims to preserve and develop the national environment for knowledge and competence generation. Elements of the system approach to the state support for innovative development of national economy are defined. Conclusions. It was outlined that the system approach requires the study of objects of state support that contribute to the innovative development of the national economy and the functioning processes of economic entities, taking into account the relationship of the relevant segments. It is substantiated that in the national innovation environment, measures of insti-tutional regulation of the innovation sphere of the country are determined by the nature of direct or indirect influence. The basic development principles of the national innovation infrastructure are determined. It is proved that ensuring the innova-tive development of the national economy in the context of the transformation of financial and economic processes is based on a combination of extensive and intensive indicators of the socio-economic system of the country. Key words: innovative development, national economy, financial and economic processes, state support.