Relevant Products Research Articles

Skeletal and Mechanistic Diversity in Ir-Catalyzed Cycloisomerizations of Allene-Tethered Pyrroles and Indoles.

Pyrroles and indoles bearing N-allenyl tethers participate in a variety of iridium-catalyzed cycloisomerization processes initiated by a C-H activation step, to deliver a diversity of synthetically relevant azaheterocyclic products. By appropriate selection of the ancillary ligand and the substitution pattern of the allene, the reactions can diverge from simple intramolecular hydrocarbonations to tandem processes involving intriguing mechanistic issues. Accordingly, a wide range of heterocyclic structures ranging from dihydro-indolizines and pyridoindoles to tetrahydroindolizines, as well as cyclopropane-fused tetrahydroindolizines can be obtained. Moreover, by using chiral ligands, these cascade processes can be carried out in an enantioselective manner. DFT studies provide insights into the underlying mechanisms and justify the observed chemo- regio- and stereoselectivities.

Soil Giant Phage: Genome and Biological Characteristics of Sinorhizobium Jumbo Phage.

This paper presents the first in-depth research on the biological and genomic properties of lytic rhizobiophage AP-J-162 isolated from the soils of the mountainous region of Dagestan (North Caucasus), which belongs to the centers of origin of cultivated plants, according to Vavilov N.I. The rhizobiophage host strains are nitrogen-fixing bacteria of the genus Sinorhizobium spp., symbionts of leguminous forage grasses. The phage particles have a myovirus virion structure. The genome of rhizobiophage AP-J-162 is double-stranded DNA of 471.5 kb in length; 711 ORFs are annotated and 41 types of tRNAs are detected. The closest phylogenetic relative of phage AP-J-162 is Agrobacterium phage Atu-ph07, but no rhizobiophages are known. The replicative machinery, capsid, and baseplate proteins of phage AP-J-162 are structurally similar to those of Escherichia phage T4, but there is no similarity between their tail protein subunits. Amino acid sequence analysis shows that 339 of the ORFs encode hypothetical or functionally relevant products, while the remaining 304 ORFs are unique. Additionally, 153 ORFs are similar to those of Atu_ph07, with one-third of the ORFs encoding different enzymes. The biological properties and genomic characteristics of phage AP-J-162 distinguish it as a unique model for exploring phage-microbe interactions with nitrogen-fixing symbiotic microorganisms.

Practical Implementation of the Sensory Utilization of Rolling Bearing Impedance Measurement: A Case Study in Machine Tool Spindle Bearings

Research into sensory utilization of the impedance measurement of rolling bearings has been intensifying for several years. However, publications in this area are mainly limited to theoretical models and experiments under laboratory conditions. In this contribution, the concept of measuring the impedance of rolling bearings for sensory utilization is implemented within a machine tool spindle. Machine tools can be found in almost all manufacturing companies for the production of components, complete products or prototypes and are therefore one of the most important and relevant production systems. The most common cause of failure is component failure, especially the rolling bearings of the spindle. Failure of the rolling bearings is often the result of incorrect operation and/or overloading. A preventative approach is the sensory monitoring of operating variables. In this work, the spindle design is modified to implement the impedance measurement of rolling bearings and then tests are carried out at free-running and under load. The impedance measurement is analyzed in time and frequency domain. Ultimately, an initial suggestion is made for features in the impedance signal that can be related to various operating parameters.

In Vivo Formation of Adrenal Organoids in a Novel Porcine Model of Adrenocortical Cell Transplantation.

Recognizing the limitations of current therapies for Addison's disease, novel treatments that replicate dynamic physiologic corticosteroid secretion, under control of ACTH, are required. The aim of these experiments was to evaluate the feasibility of adrenocortical cell transplantation (ACT) in a large animal model, adapting methods successfully used for intracutaneous pancreatic islet cell transplantation, using a fully biodegradable temporizing matrix. Autologous porcine ACT was undertaken by bilateral adrenalectomy, cell isolation, culture, and intracutaneous injection into a skin site preprepared using a biodegradable temporizing matrix (BTM) foam. Hydrocortisone support was provided during adrenocortical cell engraftment and weaned as tolerated. Blood adrenocortical hormone concentrations were monitored, and the transplant site was examined at endpoint. Outcome measures included cellular histochemistry, systemic hormone production, and hydrocortisone independence. Transplanted adrenocortical cells showed a capability to survive and proliferate within the intracutaneous site and an ability to self-organize into discrete tissue organoids with features of the normal adrenal histologic architecture. Interpretation of systemic hormone levels was confounded by the identification of accessory adrenals and regenerative cortical tissue within the adrenal bed postmortem. Corticosteroids were unable to be completely ceased. ACT in a large animal model has not previously been attempted, yet it is an important step toward clinical translation. These results demonstrate rhe potential for ACT based on the development of adrenal organoids at the BTM site. However, the inability to achieve clinically relevant systemic hormone production suggests insufficient function, likely attributable to insufficient cells through delivered dose and subsequent proliferation.

Product Placement Dalam Serial Drama Korea (Analisis Isi Kualitatif terhadap Evaluasi Atribut Product Placement Kopiko dalam Drama Korea Vincenzo)

This study aims to analyze the implementation of Kopiko product placement in the Korean drama "Vincenzo" through Russell's (2002) dimensions of product placement, while evaluating the associated attributes of Kopiko brand placement within it. Considering the attributes of Entertainment, Informativeness, and Discomfort as outlined by Ducoffe (1996), the study adopts a qualitative approach with a constructivist paradigm, utilizing content analysis as the research method. The units of analysis include episodes 14, 15, 17, and 19 of the drama "Vincenzo". The analysis results indicate that the product placement strategy successfully optimizes visual, entertainment, and informative attributes in each episode. Aligning product messages with the storyline is crucial to maintaining narrative integrity without disrupting the viewer's experience. For instance, dialogues promoting the consumption of Kopiko candies in specific scenes demonstrate effective alignment between product messaging and narrative context. The informative attribute of product placement is also demonstrated effectively, particularly in episode 19 where information about Kopiko's product advantages is conveyed through dialogue, providing added value to viewers with relevant product information aligned with product placement attributes. Nevertheless, there is a risk of discomfort from product placement if the integration of the product within the storyline is inadequate. This study underscores the importance of considering product integration with a consistent narrative to avoid disruptions to the viewer's experience.

ELECTRONICS DEVICE PURCHASE RECCOMENDATION SYSTEM USING PYTHON

Abstract: The rapid proliferation of electronics devices has led to an overwhelming number of options available to consumers, making it challenging to identify the most suitable products based on individual preferences. In this paper, we propose a novel recommendation system leveraging machine learning techniques to assist users in making informed decisions when purchasing electronics devices. Our system utilizes a collaborative filtering approach combined with feature engineering and natural language processing to analyze user preferences and product characteristics. We present the design, implementation, and evaluation of the recommendation system, demonstrating its effectiveness in suggesting personalized electronics device recommendations. Through experimentation on a realworld dataset, we showcase the system’s ability to accurately predict user preferences and provide relevant product recommendations, thereby enhancing the overall shopping experience for consumers in the electronics domain. Keywords — machine learning , database classification ,data collection,and algorithm Keywords– use rapid api for data, information visualization, gym fitness exercise application.

Streamlining the Synthesis of Pyridones through Oxidative Amination of Cyclopentenones.

Herein we report the development of an oxidative amination process for the streamlined synthesis of pyridones from cyclopentenones. Cyclopentenone building blocks can undergo in situ silyl enol ether formation, followed by the introduction of a nitrogen atom into the carbon skeleton with successive aromatisation to yield pyridones. The reaction sequence is operationally simple, rapid, and carried out in one pot. The reaction proceeds under mild conditions, exhibits broad functional group tolerance, complete regioselectivity, and is well scalable. The developed method provides facile access to the synthesis of 15N-labelled targets, industrially relevant pyridone products and their derivatives in a fast and efficient way.

Current status of the global production chain of giant river prawn (Macrobrachium rosenbergii)

Objective: To determine the current state of the global production chain of Macrobrachium rosenbergii, identifying its links and the characteristics of the techniques used. Design/Methodology/Approach: Studies over a period of 20 years (2001-2022) about the production chain of M. rosenbergii were reviewed and analyzed. The information was synthesized in tables and the most relevant production and farming data are offered as an output. Results: The following links of the production chain were identified: production, processing, and commercialization. The Macrobrachium rosenbergii farming and the main technologies used to improve its production are described. Study Limitations/Implications: There is limited systemic information about the M. rosenbergii production chain. The topics addressed the specifics of production, processing, and marketing. Findings/Conclusions: To improve the M. rosenbergii production chain, the following aspects must be guaranteed: the supply of post-larvae (PL) specimens, the development of better monoculture practices, and its integration with other species of commercial importance. The organization of the production chain must also be reviewed, considering its direct and indirect participants.

Online grocery shopping recommender systems: Common approaches and practices

Food recommender systems have been developed for the online environment to support shoppers in making informed decisions. These systems analyze the extensive data collected to infer consumer preferences and needs, providing relevant product recommendations accordingly. Despite the potential of recommender systems as a strategic marketing tool in the online grocery shopping environment, there has been limited effort to systematically analyze approaches of prior studies on recommender systems for online grocery shoppers along the five stages of recommendation delivery: (1) identify recommendation goal, (2) acquire consumer data, (3) compute, (4) evaluate, and (5) present the recommendation. Therefore, this paper examines the advancements in each stage of delivering grocery recommendations to consumers from 2018 to March 2023. We performed a search strategy resulting in 50 papers dedicated to recommender systems for online grocery shoppers, which contrasts with previous research that typically examined recipe and meal recommendations that were merely meant to inspire users on what to cook. Findings reveal a prevalence of preference-based systems with limited integration of explicit consumer data, and often lacking consent for implicit data usage. While advanced deep neural network models are getting more attention in the literature, evaluation methods tend to be system-oriented, overlooking essential user feedback and the efficacy of general metrics. This systematic literature review underscores the necessity for consumer engagement in system and interface design, aiming for grocery recommendation systems that improve customer experience, by ensuring inclusivity and prioritizing user-centered design.

Influence of neutron decay on nuclear reactor materials

While many of the leading factors for material degradation in irradiated reactor components have been identified through past studies, spontaneous neutron decay within components is a factor absent in the literature. The byproducts of neutron decay, largely composed of a proton, could lead to excessive hydrogen content, irradiation assisted stress corrosion cracking, epsilon martensite formation, hydrides, ion induced damage, voids, bubbles, and dislocation loops. Neutrons are the most abundant relevant fission product, and neutrons are continuously decaying at a rate proportional to their production. This paper hypothesizes that at high neutron fluence, a quantifiable contribution to material degradation can be associated with the proton byproducts of neutron decay. Literature-based degradation mechanisms are presented along with initial calculations of the neutron decay contribution. The paper will demonstrate a potential new factor for consideration in the material degradation of nuclear reactor components.

Sunscreen pollution is abated during the COVID-19 “Anthropause” of 2020 in two U.S. National Parks: Cape Lookout National Seashore and Kaloko-Honokōhau National Historical Park

From March to June 2020, governments across the world imposed lockdowns in an attempt to reduce the transmission of COVID-19 during the early phase of the pandemic. This period of time in which human activity slowed worldwide has been coined the “Anthropause”. The goal of this study was to determine if sunscreen pollution abated during the Anthropause and to identify the severity of the pollution when tourism/recreation recovered at two coastal units of the U.S. National Park System: Kaloko-Honokōhau National Historical Park in Hawaiʻi, U.S.A. and Cape Lookout National Seashore in North Carolina, U.S.A. Active ingredients of sunscreen products were measured in water and sand samples at both locations, including oxybenzone, octinoxate, octocrylene, octisalate, homosalate, and relevant breakdown products of some of these ingredients. A risk assessment was conducted on Anthropause and post-Anthropause contaminant levels for both locations to determine if there was a threat reduction during the Anthropause, and whether tourism recovery in the post-Anthropause period served as a threat to coastal wildlife. Both national park units exhibited an almost absolute reduction in the levels of sunscreen contamination during the Anthropause period, a striking commonality considering the geographic expanse separating the parks. Once travel restrictions were lifted, a large influx of tourists ensued at both locations, resulting in a relatively sudden and dangerous increase in the levels of sunscreen chemical pollution. This study supports the argument that unmanaged tourism is a source of coastal sunscreen pollution that poses a threat to the localized continuity of species populations and biodiversity, especially to coral reefs and fisheries.

Piston reactor for chemical energy storage: Modeling study to explore electro-mechanical conversion route using propane feedstock

Within the context of renewables and chemical energy storage, this work aims to explore chemical reaction conversion through the electro-mechanical route which is different from the commonly employed electro-thermal and electro-chemical conversion methods. Piston reactor is a novel equipment concept that can couple the rotational movement from an electric motor to a reciprocating piston within an enclosed reaction chamber resembling the operation of an internal combustion engine. Exploration of a reactor technology still in the laboratory stage requires an assessment of reaction intermediate mixtures to identify potential leads. This work uses a systematic methodology to assess these intermediate mixtures beyond typical reactor yield metrics to include economic values as part of the decision-making toward identifying lead candidates. Rather than focusing on a specific target reaction or product, this work is carried out as a model-driven study to cover a wider range of conditions and product scenarios. Propane as the main feedstock is selected because it is easier to trigger in the piston reactor, it is not a complex feed, a detailed kinetic mechanistic model is available to study it, and most importantly it can generate a wide range of industrially relevant products to serve the purpose of this study. The study revealed that the highly endothermic propane pyrolysis reaction requires intake temperatures larger than 950 K which is impractical. Diluting the feed with argon is one way to lower this intake temperature and achieve desirable conversion. This however is impractical because of additional separation steps and reduced production capacity. Thermal coupling of propane pyrolysis with exothermic side reactions by co-feeding oxygen, water, or carbon dioxide are investigated and showed promising results. A diverse range of products are produced such as hydrogen, carbon monoxide, ethylene, and propylene, achieving high conversions (>90 %), while simultaneously generating useful work and process heat. Unconventional triggers such as using ozone to generate radicals and trigger ignition are investigated to further lower the intake temperature requirements. The explored solution space is then evaluated considering a new reactor metric as the value of products mixture stream. Regions of high-value products do not match those obtained using the traditional yield metrics. This shows the importance of what metrics to use for assessing reactors with wide range of reaction mixture intermediates as the piston reactor. Full economic analysis and optimization are the right direction in the future to properly assess the potential of piston reactor technology.

Fast Photoactuation and Environmental Response of Humidity-Sensitive pDAP-Silicon Nanocantilevers.

Multi-responsive nanomembranes are a new class of advanced materials that can be harnessed in complex architectures for micro and nano-manipulators, artificial muscles, energy harvesting, soft robotics, and sensors. The design and fabrication of responsive membranes must meet such challenges as trade-offs between responsiveness and mechanical durability, volumetric low-cost production ensuring low environmental impact, and compatibility with standard technologies or biological systems This work demonstrates the fabrication of multi-responsive, mechanically robust poly(1,3-diaminopropane) (pDAP) nanomembranes and their application in fast photoactuators. The pDAP films are developed using a plasma-assisted polymerization technique that offers large-scale production and versatility of potential industrial relevance. The pDAP layers exhibit high elasticity with the Young's modulus of ≈7 GPa and remarkable mechanical durability across 20-80°C temperatures. Notably, pDAP membranes reveal immediate and reversible contraction triggered by light, rising temperature, or reducing relative humidity underpinned by a reversible water sorption mechanism. These features enable the fabrication of photoactuators composed of pDAP-coated Si nanocantilevers, demonstrating ms timescale response to light, tens of µm deflections, and robust performance up to kHz frequencies. These results advance fundamental research on multi-responsive nanomembranes and hold the potential to boost versatile applications in light-to-motion conversion and sensing toward the industrial level.

Bakron’s Linguistic View on “Jahon-Name”

The article dwells on the issue concerned with the study of Bakron’s linguistic view on “Jahon-Name”. It is underscored that the relevant geographical production is considered to be one of the most important works. It is determined that the word stock of “Jahon-Name” includes the following lexicons denoting: locality, natural phenomena, elements, social areas, notions of quantity, period and seasons, person, occupation, profession, skill, animals, somatisms, scientifico-professional terms, minerals, agricultural, food and beverage, notions dealing with religion and various objects. Adducing the result of an analysis beset with the theme explored one can come to the conclusion that “Jahan-Name” refers to geographical literature and its author makes an endeavor to edit the language; to use public vocabulary; to indicate correct pronunciation and spelling of words; to fix the meaning of various lexical elements; to determine linguistic belonging of words; to make obvious and hidden errors; to state hypotheses concerning the origin of names; to point out differences in the names of localities in written and colloquial form – all this is considered to be peculiarities of the language of the relevant work.

Perjalanan Songket: Transformasi Menghidupkan UMKM di Kota Palembang

Songket, as one of Indonesia's textile cultural heritage, has a long history that reflects the richness of tradition and outstanding craftsmanship. However, in recent decades, songket has faced challenges that threaten its survival, including fashion changes, lack of artisan regeneration, and competition with modern textile products. This article explores the journey of songket from its heyday in the past to the revitalization efforts made to restore that glory in the modern era. Through a qualitative approach, this study explores strategies applied by various stakeholders, including craftsmen, designers, government, and communities, to maintain and promote songket as a relevant cultural product with high economic value. Case studies from various songket-producing regions in Indonesia show that design innovation, education, and cross-sector collaboration play an important role in this process. The results of this study provide insight into how reviving cultural heritage can be a source of pride and economic sustainability for local communities. In conclusion, songket's journey from heritage dreams to real glory is an inspiring example of how traditional cultural richness can be integrated into contemporary contexts to create sustainable benefits.

Discovery, characterization, and engineering of an advantageous Streptomyces host for heterologous expression of natural product biosynthetic gene clusters

BackgroundStreptomyces is renowned for its robust biosynthetic capacity in producing medically relevant natural products. However, the majority of natural products biosynthetic gene clusters (BGCs) either yield low amounts of natural products or remain cryptic under standard laboratory conditions. Various heterologous production hosts have been engineered to address these challenges, and yet the successful activation of BGCs has still been limited. In our search for a valuable addition to the heterologous host panel, we identified the strain Streptomyces sp. A4420, which exhibited rapid initial growth and a high metabolic capacity, prompting further exploration of its potential.ResultsWe engineered a polyketide-focused chassis strain based on Streptomyces sp. A4420 (CH strain) by deleting 9 native polyketide BGCs. The resulting metabolically simplified organism exhibited consistent sporulation and growth, surpassing the performance of most existing Streptomyces based chassis strains in standard liquid growth media. Four distinct polyketide BGCs were chosen and expressed in various heterologous hosts, including the Streptomyces sp. A4420 wild-type and CH strains, alongside Streptomyces coelicolor M1152, Streptomyces lividans TK24, Streptomyces albus J1074, and Streptomyces venezuelae NRRL B-65442. Remarkably, only the Streptomyces sp. A4420 CH strain demonstrated the capability to produce all metabolites under every condition outperforming its parental strain and other tested organisms. To enhance visualization and comparison of the tested strains, we developed a matrix-like analysis involving 15 parameters. This comprehensive analysis unequivocally illustrated the significant potential of the new strain to become a popular heterologous host.ConclusionOur engineered Streptomyces sp. A4420 CH strain exhibits promising attributes for the heterologous expression of natural products with a focus on polyketides, offering an alternative choice in the arsenal of heterologous production strains. As genomics and cloning strategies progress, establishment of a diverse panel of heterologous production hosts will be crucial for expediting the discovery and production of medically relevant natural products derived from Streptomyces.

Sustainable transparency on recommender systems: Bayesian ranking of images for explainability

Recommender Systems have become crucial in the modern world, commonly guiding users towards relevant content or products, and having a large influence over the decisions of users and citizens. However, ensuring transparency and user trust in these systems remains a challenge; personalized explanations have emerged as a solution, offering justifications for recommendations. Among the existing approaches for generating personalized explanations, using existing visual content created by users is a promising option to maximize transparency and user trust. State-of-the-art models that follow this approach, despite leveraging highly optimized architectures, employ surrogate learning tasks that do not efficiently model the objective of ranking images as explanations for a given recommendation; this leads to a suboptimal training process with high computational costs that may not be reduced without affecting model performance. This work presents BRIE, a novel model where we leverage Bayesian Pairwise Ranking to enhance the training process, allowing us to consistently outperform state-of-the-art models in six real-world datasets while reducing its model size by up to 64 times and its CO2 emissions by up to 75% in training and inference.

The complementary effects of ‘Made in China 2025’ industrial policy and trade liberalisation on China’s export of relevant products

ABSTRACT This research explores the synergy between China's 'Made in China 2025' (MIC25) policy and trade liberalization through FTAs, particularly their effect on export margins. Analyzing China's MIC25 product exports from 2011-2019 using DID models, it was found that post-MIC25 implementation, relevant exports saw marked growth in both intensive and quantity margins. Regression analysis revealed the China-Korea FTA significantly improved the quality or price margins of China's MIC25 exports to Korea. The increase in price margins was notably higher in FTA-partner countries. These findings indicate that FTAs enhance industrial policies by bettering market access and reducing costs for high-quality MIC25 products. This study adds to the discourse on trade liberalization and industrial policy's role in export performance, offering valuable insights for policymakers and businesses to understand trade policy impacts and craft industrial strategies complemented by trade liberalization.

"Old Wine in a New Bottle" -- A Study on Consumer Acceptance of "Blind Leftovers Box"

The blind box of leftovers is an innovative catering marketing model. In recent years, this marketing model has been regarded as an effective measure to reduce food waste in Chinese cities and relieve the operating pressure of catering enterprises. This study uses the literature review method to search and sort out the practical experience of some enterprises in the blind leftover box business and reports on the blind leftover box; Then the questionnaire survey method is adopted to explore whether consumers accept the blind leftovers box. The purpose is to investigate the acceptance degree of consumers to the blind leftovers box and the factors affecting the acceptance degree and provide feasible suggestions for catering enterprises to adjust the relevant product marketing strategy in the future. Based on the results of the questionnaire survey, it is found that consumers who accept the blind leftover box generally think that the blind leftover box has the advantages of the novel form, high-cost performance, and food saving. Consumers who reject the blind leftover box are concerned about the reasonable value and food safety of the blind leftover box. The research shows that relevant catering enterprises should strengthen the publicity of blind leftover boxes, and carry out differentiated marketing for people of different ages and different consumption levels.

Explore the Application of Machine Vision Technology in the Automation of Machinery Manufacturing

The continuous acceleration of China’s industrialization process has made automation and intelligent technologies increasingly dominant. Implementing these technologies can enhance machining and production efficiency, free up manpower, automate machinery manufacturing processes, and yield greater economic benefits. Thus, this paper outlines the key applications of machine vision technology in modern machinery manufacturing automation. It discusses how machine vision can contribute to core functions such as workpiece measurement, detection, and robot welding, facilitating automation, intelligence, and sustainable development. The aim is for the findings of this paper to offer valuable insights into relevant professions and production processes, thereby catalyzing the pace of mechanical manufacturing automation.