The influence of quantum effects on the interaction of intense laser fields with plasmas is investigated by using a hydrodynamic model based on the framework of the relativistic quantum theory. Starting from the covariant Wigner function and Dirac equation, the hydrodynamic equations for relativistic quantum plasmas are derived. Based on the relativistic quantum hydrodynamic equations and Poisson equation, the perturbations of electron number densities and the electric field of the laser wakefield containing quantum effects are deduced. It is found that the corrections generated by the quantum effects to the perturbations of electron number densities and the accelerating field of the laser wakefield cannot be neglected. Quantum effects will suppress laser wakefields, which is a classical manifestation of quantum decoherence effects, however, the contribution of quantum effects for the laser wakefield correction will been partially counteracted by the relativistic effects. The analysis also reveals that quantum effects enlarge the effective frequencies of plasmas, and the quantum behavior appears a screening effect for plasma electrons.