Relative Band Research Articles

An olfactory figure-ground segregation: The resistance fluctuation analysis of acetone gas for acetone/random gas mixtures recognition

Recognizing the disease-specific odor in human breath is a feasible non-invasive disease detection strategy. The most critical issue of olfactory diagnosis lies in recognizing the target gas among complex respiration compounds accurately. This paper demonstrated a novel approach to binary gas mixture recognition, exploring nature-related features of the target “odor object” (acetone gas) regardless of its “noisy background” (ethanol or methanol gases). Those features were extracted from time-series resistance fluctuations collected with one conventional SnO2 thin film gas sensor (TF) or our sensitivity-controllable lines gas sensor (TL). 6 features (variance, root mean square, band power, relative band power, entropy, and the number of values crossing mean value) were selected and analyzed with k-Nearest Neighbor regressor (KNN) and Support Vector Regressor (SVR). 18 types of acetone/ethanol mixtures and 3 acetone/methanol mixtures were tested with the proposed models and further explained with SHAP (SHapley Additive exPlanations). The model of TL and KNN achieved the optimal performance of regressing acetone concentrations with the coefficient of determination (R2) of 0.97 and 0.95 in individual gas and binary gas mixtures, respectively. Entropy was found to be the key feature that was linked to sensor properties. Finally, acetone gas data mixed with simulated gas and random noise data were experimented to evaluate our models’ potential for acetone/random gas mixture recognition and robustness.

Diethylbenzene and ethyltoluene adsorption studies on novel beta antimonide phosphorus nanosheets-a first-principle study.

In the present work, we examined the sensing behavior of monolayer beta antimonide phosphorus (β-SbP) sheets towards toxic volatile organic compounds (VOCs) namely, 1,2-diethylbenzene and 2-ethyltoluene using density functional theory (DFT) method. At first, using cohesive energy structural stability of the monolayer β-SbP is confirmed. The calculated energy band gap value of monolayer β-SbP is 2.168eV, which is a semiconductor. Furthermore, the adsorption properties of 1,2-diethylbenzene and 2-ethyltoluene on β-SbP are studied through key factors, such as adsorption energy, Mulliken charge transfer, and relative band gap variation. The adsorption energy clearly shows (- 0.335 to - 0.903eV) that both 1,2-diethylbenzene and 2-ethyltoluene are physisorbed on β-SbP monolayer. Besides, Mulliken charge transfer falls in the range of - 0.465 to 0.933 e; this information clearly shows that the β-SbP monolayer is a potential candidate for sensing 1,2-diethylbenzene and 2-ethyltoluene molecules. The structural firmness including electronic and adsorption properties of 1,2-diethylbenzene and 2-ethyltoluene on β-SbP monolayer are investigated with the support of the DFT method. Particularly, the hybrid generalized gradient approximation (hybrid GGA) along with Beck's three-parameter + Lee-Yang-Parr (B3LYP) exchange-correlation functional is utilized for relaxing the β-SbP monolayer. In the present work, all calculations are performed using the Quantum Atomistic Tool Kit (ATK) simulation package. In the present work, we utilized β-SbP monolayer as a chief sensing element to detect 1,2-diethylbenzene and 2-ethyltoluene to safeguard humans from toxic environments.

The band count imprecision - a Croatian multicentric pilot study.

Due to high inter-observer variability the 2015 International Council for Standardization in Haematology (ICSH) recommendations state to count band neutrophils as segmented neutrophils in the white blood cell (WBC) differential. However, the inclusion of bands as a separate cell entity within the WBC differential is still widely used in hematology laboratories in Croatia. The aim of this multicentric study was to assess the degree of inter-observer variability in enumerating band neutrophils within the WBC differential among Croatian laboratories. Seven large Croatian hospital laboratories from different parts of the country participated in the study. In each of 7 participating laboratories, one blood smear, that was flagged by the analyzer as possibly having bands, was evaluated by all personnel participating in the analysis of hematology samples. Between-observer manual smear reproducibility was expressed as coefficient of variation (CV) and calculated using the following formula: CV (%) = (standard deviation (SD)/mean value) x 100%. The CVs (%) and relative band neutrophil counts in participating laboratories were as follows: 15.4% (16-24), 19.2% (16-32), 19.5% (17-40), 21.1% (17-44), 35.0% (8-26), 51.9% (3-29), and remarkably high 62.4% (12-59). For segmented neutrophils CVs were lower, ranging from 7.4% to 32.2%. The CVs did not correlate with the number of staff members in each hospital (P = 0.293). This study revealed very high variability in enumerating band neutrophil count in the blood smear differential among all participants, thus prompting a need for action on a national level.

Identifying epileptogenic abnormality by decomposing intracranial EEG and MEG power spectra

BackgroundAccurate identification of abnormal electroencephalographic (EEG) activity is pivotal for diagnosing and treating epilepsy. Recent studies indicate that decomposing brain activity into periodic (oscillatory) and aperiodic (trend across all frequencies) components can illuminate the drivers of spectral activity changes. New methodsWe analysed intracranial EEG (iEEG) data from 234 subjects, creating a normative map. This map was compared to a cohort of 63 patients with refractory focal epilepsy under consideration for neurosurgery. The normative map was computed using three approaches: (i) relative complete band power, (ii) relative band power with the aperiodic component removed, and (iii) the aperiodic exponent. Abnormalities were calculated for each approach in the patient cohort. We evaluated the spatial profiles, assessed their ability to localize abnormalities, and replicated the findings using magnetoencephalography (MEG). ResultsNormative maps of relative complete band power and relative periodic band power exhibited similar spatial profiles, while the aperiodic normative map revealed higher exponent values in the temporal lobe. Abnormalities estimated through complete band power effectively distinguished between good and bad outcome patients. Combining periodic and aperiodic abnormalities enhanced performance, like the complete band power approach. Comparison with existing methods and conclusionsSparing cerebral tissue with abnormalities in both periodic and aperiodic activity may result in poor surgical outcomes. Both periodic and aperiodic components do not carry sufficient information in isolation. The relative complete band power solution proved to be the most reliable method for this purpose. Future studies could investigate how cerebral location or pathology influences periodic or aperiodic abnormalities.

The Defects Genome of Janus Transition Metal Dichalcogenides.

2D Janus Transition Metal Dichalcogenides (TMDs) have attracted much interest due to their exciting quantum properties arising from their unique two-faced structure, broken-mirror symmetry, and consequent colossal polarization field within the monolayer. While efforts are made to achieve high-quality Janus monolayers, the existing methods rely on highly energetic processes that introduce unwanted grain-boundary and point defects with still unexplored effects on the material's structural and excitonic properties Through high-resolution scanning transmission electron microscopy (HRSTEM), density functional theory (DFT), and optical spectroscopy measurements; this work introduces the most encountered and energetically stable point defects. It establishes their impact on the material's optical properties. HRSTEM studies show that the most energetically stable point defects are single (VS and VSe) and double chalcogen vacancy (VS -VSe), interstitial defects (Mi), and metal impurities (MW) and establish their structural characteristics. DFT further establishes their formation energies and related localized bands within the forbidden band. Cryogenic excitonic studies on h-BN-encapsulated Janus monolayers offer a clear correlation between these structural defects and observed emission features, which closely align with the results of the theory. The overall results introduce the defect genome of Janus TMDs as an essential guideline for assessing their structural quality and device properties.

Novel arsenborane as a sensing material for dichlorofluoromethane and dichlorodifluoromethane vapours – A first-principles study

Presently, two-dimensional (2D) materials are cutting-edge research to detect air pollutants in the environment. In this research study, we used arsenborane as a sensing element towards halomethanes viz. dichlorofluoromethane (Freon 21) and dichlorodifluoromethane (Freon 12). At first, the structural firmness of bare arsenborane is confirmed based on formation energy, phonon band spectrum, and ab initio molecular dynamics simulation. Also, the electronic property of bare stable arsenborane is investigated by plotting bands and projected-density-of-states (PDOS) maps. The energy gap of arsenborane is computed to be 0.927 eV which confirms semiconductor nature. Significantly, the interaction behaviour of Freon 21 and Freon 12 on arsenborane is studied with the influence of relative band gap changes, Mulliken-charge analysis, and adsorption energy. In the present work, the calculated value of adsorption energy is observed in the scope of −0.083 eV to −0.618 eV (physisorption regime). Thus, based on the outcome we suggest that the new 2D material arsenborane is a good base material to detect Freon 21 and Freon 12 vapours in the air environment.

Aberrant Brain Networks and Relative Band Power in Patients with Acute Anti-NMDA Receptor Encephalitis: A Study of Resting-State EEG.

The alterations of the functional network (FN) in anti-N-methyl-Daspartate receptor (NMDAR) encephalitis have been recognized by functional magnetic resonance imaging studies. However, few studies using the electroencephalogram (EEG) have been performed to explore the possible FN changes in anti-NMDAR encephalitis. In this study, the aim was to explore any FN changes in patients with anti-NMDAR encephalitis. Twenty-nine anti-NMDAR encephalitis patients and 29 age- and gender-matched healthy controls (HC) were assessed using 19-channel EEG examination. For each participant, five 10-second epochs of resting state EEG with eyes closed were extracted. The cortical source signals of 84 Brodmann areas were calculated using the exact low resolution brain electromagnetic tomography (eLORETA) inverse solution by LORETA-KEY. Phase Lag Index (PLI) matrices were then obtained and graph and relative band power (RBP) analyses were performed. Compared with healthy controls, functional connectivity (FC) in the delta, theta, beta 1 and beta 2 bands significantly increased within the 84 cortical source signals of anti-NMDAR encephalitis patients (p < 0.05) and scalp FC in the alpha band decreased within the 19 electrodes. Additionally, the anti-NMDAR encephalitis group exhibited higher local efficiency and clustering coefficient compared to the healthy control group in the four bands. The slowing band RBP increased while the fast band RBP decreased in multiple-lobes and some of these changes in RBP were correlated with the modified Rankin Scale (mRS) and Mini-mental State Examination (MMSE) in anti-NMDAR encephalitis patients. This study further deepens the understanding of related changes in the abnormal brain network and power spectrum of anti-NMDA receptor encephalitis. The decreased scalp alpha FC may indicate brain dysfunction, while the increased source beta FC may indicate a compensatory mechanism for brain function in anti-NMDAR encephalitis patients. These findings extend understanding of how the brain FN changes from a cortical source perspective. Further studies are needed to detect correlations between altered FNs and clinical features and characterize their potential value for the management of anti-NMDAR encephalitis.

Role of Semiconductive Property on Selective Cementation Mechanism of Iron Oxides to Gold in Galvanic Interaction with Zero-Valent Aluminum from Gold–Copper Ammoniacal Thiosulfate Solutions

Iron oxides (hematite, Fe2O3, and magnetite, Fe3O4), previously used as electron mediators in the galvanic system with zero-valent aluminum (ZVAl), have been shown to recover Au upon cementation in Au–Cu ammoniacal thiosulfate media selectively, and this warrants further investigation. This research is focused on investigating the role of the semiconductive properties of metal oxides by performing a cementation experiment by mixing 0.15 g of electron mediators (Fe3O4, Fe2O3, TiO2 (anatase and rutile)) and 0.15 g of zero-valent aluminum powder as an electron donor in various electrochemical experiments. The results revealed that upon the cementation experiment, synthetic Fe2O3 and Fe3O4 were consistently able to selectively recover Au at around 90% and Cu at around 20%. Compared to activated carbon (AC), TiO2, in anatase and rutile forms, obtained selective recovery of gold, but the recovery was utterly insignificant compared to that of iron oxides, obtaining an average of 93% Au and 63% Cu recovery. The electrochemical and surface analysis supports the results obtained upon the cementation process, where TiO2, upon cyclic voltammetry (CV), obtained two reduction peaks centered at −1.0 V and −0.5 V assigned to reducing Au and Cu ions, respectively. Furthermore, various electrochemical impedance spectroscopic analyses revealed that the flat band potential obtained in the Mott–Schottky plot is around −1.0 V and −0.2 V for iron oxides and titanium oxides, respectively, suggesting that the electrons travel from semiconductor interface to electrolyte interface, and electrons are accessible only to Au ions in the electrolyte interface (reduction band edge around −1.0 V). The determination of this selective cementation mechanism is one of a kind. It has been proposed that the semiconductive properties of Fe2O3, Fe3O4, and, by configuring their relative energy band diagram, the travel of electrons from the iron oxide–electrolyte interface facilitate the selective cementation towards Au(S2O3)23+ ions in gold–copper ammoniacal thiosulfate solutions.

Architectural Neuroimmunology: A Pilot Study Examining the Impact of Biophilic Architectural Design on Neuroinflammation

Recent research in architectural neuroscience has found that visual exposure to biophilic design may help reduce occupant physiological stress responses. However, there are still significant gaps in our understanding of the complex ways in which biophilic design impacts on building occupant neurophysiology. The relationship between visual exposure to biophilic design and neurophysiological responses such as neuroinflammation have yet to be directly investigated. This paper examines the results of a pilot study that was established to investigate the relationship between visual exposure to biophilic design and neuroinflammation, as mediated by physiological stress responses. The pilot study utilised a 32-channel quantitative electroencephalograph (qEEG) to assess the relative changes in neuroinflammatory markers (relative alpha and relative delta power band activity) of 10 participants while they were exposed to 2D digital images of buildings that visually expressed varying degrees of biophilic design. Participants exhibited a decrease in relative delta power when exposed to higher levels of biophilic design. No statistically significant changes in relative alpha power were observed. These findings suggest that exposure to buildings with higher degrees of biophilia may result in decreased neuroinflammatory activity. In doing so, this research works to further develop our understanding of the complex ways in which the built environment impacts on occupant neuroinflammation and physiological stress.

Investigating the impact of Mahā Mantra chanting on anxiety and depression : An EEG Rhythm Analysis Approach

Hare kṛṣṇa hare kṛṣṇa kṛṣṇa kṛṣṇa hare hare hare rāma hare rāma rāma rāma hare hare is the Mahā Mantra (MM). The Mantra is believed to be the sacred mantra from the ancient times. In the current research, an attempt has been made to study the brain dynamics of oscillatory changes after MM chanting. The mantra chanting produces a state of mind that has a positive effect on the individual’s brain. The electroencephalogram (EEG) signals are asynchronous in nature and record the brain's present state. In this study, forty individuals were assigned randomly into two (pre &post) groups,(n=20) with equal ratio of male and female and having mean age 25.5 yr. EEG signal was recorded in eyes closed condition both prior as well as after the MM chanting. The rhythms (Delta, theta, alpha, beta, and gamma) were extracted from the recorded EEG signals. To match the behavioural changes in the nature of the EEG, the power of the rhythm was computed and compared. According to the study, chanting MM leads to increase in alpha relative power in the central and parietal regions of the brain, which indicates that the brain has been refreshed and relieved. The study showed generous production of alpha, theta and delta waves which has been found in the study to be associated with the secretion of hormones or neurotransmitters causing dilation of blood vessels. As per literature it has been found that increase in relative alpha band power is associated with the secretion of hormones or neurotransmitters causing dilation of blood vessels which is further associated with the improvement in the mental well-being and feeling relaxed and releived, thus leading to decrease in anxiety and depression. The current research study proves the impact of the MM chanting leads to mental alleviation and mental well-being to a great extent.

Highly active ZnO/Fe3+-TiO2 photocatalysts for visible-light photodegradation application and its colour change behaviour by d-d transition

Highly active novel ZnO/Fe-TiO2 composite catalysts with p-n junction heterostructure have been fabricated by adding commercial ZnO and sol–gel derived Fe-TiO2 nano-powders controlled by grinding and drying. This work reported that doped Fe (III) with TiO2 form a p-type semiconductor and whereas ZnO is an n-type semiconductor. The slight variation of electronegativity between ZnO and TiO2 causes a strong rectifying action for the formation of an interface between ZnO and Fe-TiO2. The occurrence of red shift phenomenon in absorption spectrum of the samples suggest the outcome of d-d transition of Fe3+ (2T2g → 2A2g, 2T1g) and the charge transfer transition between interacting Fe3+ ions (Fe3+ + Fe3+ → Fe4+ + Fe2+). These Fe3+ 3d states in addition to oxygen vacancies and Ti3+ centers create band states, thereby favouring the electronic transition to these levels and resulting in narrowing of TiO2 band gap. A direct confirmation is the increase of Urbach energy with the lowering in the band gap of ZnO/Fe-TiO2.The crystal field splitting of d orbitals (5 degenerate orbitals) of Fe3+ and the approach of free ligand ions which split into two sets and Fe3+ ligand field transition is discussed schematically. The photocatalytic activities of these heterostructure photocatalysts were evaluated by degrading toxic cationic organic dyes such as Methylene Blue (MB) and Malachite Green Oxalate (MG) under visible light. The mechanism of photocatalysis has been recommended which is based on the relative band structure of the semiconductor and integrated heterostructure. The formation of a spike barrier in the CB at the interface gives rise to trap sites that capture the migration of charge carriers and occurs recombination of electron-hole pair at higher Fe(III) doping concentration. The dark adsorption property of the catalysts sample has been also studied.

Exploration of new Janus GeBrI monolayer for optoelectronic and spintronic applications

Two-dimensional (2D) materials have been explored for diverse applications, where multifunctional candidates with two or more functions are desired. In this work, new Janus GeBrI monolayer with interesting electronic and magnetic properties is investigated. Standard PBE and hybrid HSE06 functionals assert the indirect gap semiconductor behavior of pristine monolayer with band gap of 2.28 and 3.04 eV, respectively. Novel feature-rich properties can be induced in Janus GeBrI monolayer by defect engineering and doping. Specifically, single Ge vacancy (VGe) metalizes the monolayer without magnetism. Similarly, the non-magnetic nature is kept by doping with IIA-group (Be and Mg: BeGe and MgGe) atoms, where the energy gap exhibits a slight increase of the order between 1.32% and 3.51%. In contrast, this 2D material is significantly magnetized by single halogen vacancy (VBr and VI), doping with IIIA-group (Al and Ga: AlGe and GaGe) atoms, and doping with chalcogen (Se and Te: SeBr, SeI, TeBr, and TeI) atoms. In these cases, total magnetic moments between 0.61 and 1.00 μB are obtained, where impurities and those atoms closest to the defect/doping site originate mainly the system magnetism. Moreover, VBr, VI, AlGe, GaGe systems exhibit the diluted magnetic semiconductor nature, while SeBr, SeI, TeBr, and TeI systems are classified as 2D half-metallic structures. Further, Bader charge analysis indicates the charge loser of IIIA- and IIA-group impurities when transferring charge to the host monolayer. Meanwhile, chalcogen dopants are charge gainers attracting charge from the host monolayer. The presented results introduce new stable Janus GeBrI monolayer with relative large intrinsic band gap, further functionalization processes based on the vacancy defects and doping of this 2D material may make prospective 2D spintronic materials.

Removal of movement artifacts and assessment of mental stress analyzing electroencephalogram of non-driving passengers under whole-body vibration.

The discomfort caused by whole-body vibration (WBV) has long been assessed using subjective surveys or objective measurements of body acceleration. However, surveys have the disadvantage that some of participants often express their feelings in a capricious manner, and acceleration data cannot take into account individual preferences and experiences of their emotions. In this study, we investigated vibration-induced mental stress using the electroencephalogram (EEG) of 22 seated occupants excited by random vibrations. Between the acceleration and the EEG signal, which contains electrical noise due to the head shaking caused by random vibrations, we found that there was a strong correlation, which acts as an artifact in the EEG, and therefore we removed it using an adaptive filter. After removing the artifact, we analyzed the characteristics of the brainwaves using topographic maps and observed that the activities detected in the frontal electrodes showed significant differences between the static and vibration conditions. Further, frontal alpha asymmetry (FAA) and relative band power indices in the frontal electrodes were analyzed statistically to assess mental stress under WBV. As the vibration level increased, EEG analysis in the frontal electrodes showed a decrease in FAA and alpha power but an increase in gamma power. These results are in good agreement with the literature in the sense that FAA and alpha band power decreases with increasing stress, thus demonstrating that WBV causes mental stress and that the stress increases with the vibration level. EEG assessment of stress during WBV is expected to be used in the evaluation of ride comfort alongside existing self-report and acceleration methods.

Associations between EEG power and coherence with cognition and early precursors of speech and language development across the first months of life.

The neural processes underpinning cognition and language development in infancy are of great interest. We investigated EEG power and coherence in infancy, as a reflection of underlying cortical function of single brain region and cross-region connectivity, and their relations to cognition and early precursors of speech and language development. EEG recordings were longitudinally collected from 21 infants with typical development between approximately 1 and 7 months. We investigated relative band power at 3-6Hz and 6-9Hz and EEG coherence of these frequency ranges at 25 electrode pairs that cover key brain regions. A correlation analysis was performed to assess the relationship between EEG measurements across frequency bands and brain regions and raw Bayley cognitive and language developmental scores. In the first months of life, relative band power is not correlated with cognitive and language scales. However, 3-6Hz coherence is negatively correlated with receptive language scores between frontoparietal regions, and 6-9Hz coherence is negatively correlated with expressive language scores between frontoparietal regions. The results from this preliminary study contribute to the existing literature on the relationship between electrophysiological development, cognition, and early speech precursors in this age group. Future work should create norm references of early development in these domains that can be compared with infants at risk for neurodevelopmental disabilities.

Experimental study on aerial detection of concrete microcracks based on fluorescent selective excitation

ABSTRACT In order to solve the problem of detecting and finding microcracks on concrete structures, a method on aerial detection of concrete microcracks based on fluorescence selective excitation was proposed in this study. Concentration brightness relationship curves for fluorescent solutions were plotted based on experimental analysis results. Specialised fluorescent aqueous solutions for concrete microcrack detection were identified as excitation reagents by integrating with the fluorescence development patterns of each solution. Concrete specimens containing authentic microcracks were prepared, and fluorescence selective excitation detection tests for concrete microcracks were conducted. The morphology of microcrack development under fluorescent labelling was scrutinised, and the intervals of opening widths for the examined cracks were quantified. The findings demonstrate that concrete microcracks draw surrounding fluorescent solutions into the cracks through capillary adsorption. Under UV radiation, microcracks manifest dark bands in relation to the fluorescence attachment area due to the loss of fluorescent solution around them. This band elucidates the location and morphology of the marked crack, amplifying its visual representation. Furthermore, the fluorescence selective excitation UV detection method proves effective in identifying concrete microcracks with a width as small as 0.02 mm. The improved UAV equipment was used to carry out the aerial detection experiment on the actual concrete structure.

Relative band power in assessing temporary neurological dysfunction post- type A aortic dissection surgery: a prospective study

Temporary neurological dysfunction (TND), a common complication following surgical repair of Type A Aortic Dissection (TAAD), is closely associated with increased mortality and long-term cognitive impairment. Currently, effective treatment options for TND remain elusive. Therefore, we sought to investigate the potential of postoperative relative band power (RBP) in predicting the occurrence of postoperative TND, with the aim of identifying high-risk patients prior to the onset of TND. We conducted a prospective observational study between February and December 2022, involving 165 patients who underwent surgical repair for TAAD at our institution. Bedside Quantitative electroencephalography (QEEG) was utilized to monitor the post-operative brain electrical activity of each participant, recording changes in RBP (RBP Delta, RBP Theta, RBP Beta and RBP Alpha), and analyzing their correlation with TND. Univariate and multivariate analyses were employed to identify independent risk factors for TND. Subsequently, line graphs were generated to estimate the incidence of TND. The primary outcome of interest was the development of TND, while secondary outcomes included intensive care unit (ICU) admission and length of hospital stay. A total of 165 patients were included in the study, among whom 68 (41.2%) experienced TND. To further investigate the independent risk factors for postoperative TND, we conducted both univariate and multivariate logistic regression analyses on all variables. In the univariate regression analysis, we identified age (Odds Ratio [OR], 1.025; 95% CI, 1.002–1.049), age ≥ 60 years (OR, 2.588; 95% CI, 1.250–5.475), hemopericardium (OR, 2.767; 95% CI, 1.150–7.009), cardiopulmonary bypass (CPB) (OR, 1.007; 95% CI, 1.001–1.014), RBP Delta (OR, 1.047; 95% CI, 1.020–1.077), RBP Alpha (OR, 0.853; 95% CI, 0.794–0.907), and Beta (OR, 0.755; 95% CI, 0.649–0.855) as independent risk factors for postoperative TND. Further multivariate regression analyses, we discovered that CPB time ≥ 180 min (OR, 1.021; 95% CI, 1.011–1.032), RBP Delta (OR, 1.168; 95% CI, 1.105–1.245), and RBP Theta (OR, 1.227; 95% CI, 1.135–1.342) emerged as independent risk factors. TND patients had significantly longer ICU stays (p < 0.001), and hospital stays (p = 0.002). We obtained the simplest predictive model for TND, consisting of three variables (CPB time ≥ 180 min, RBP Delta, RBP Theta, upon which we constructed column charts. The areas under the receiver operating characteristic (AUROC) were 0.821 (0.755, 0.887). Our study demonstrates that postoperative RBP monitoring can detect changes in brain function in patients with TAAD during the perioperative period, providing clinicians with an effective predictive method that can help improve postoperative TND in TAAD patients. These findings have important implications for improving clinical care in this population.Trial registration ChiCTR2200055980. Registered 30th Jan. 2022. This trial was registered before the first participant was enrolled.

Potentials of spaceborne imaging spectrometer PRISMA, ASTER, and ALOS-1 PALSAR datasets for mineral mapping and geological controls of mineral deposit in Jahazpur, Rajasthan, India

Palaeoproterozoic rocks of the Jahazpur region are well known for talc mineralization and its mining. The present study attempts to identify and map the talc and associated minerals and their structural control using multi-source remote sensing datasets. Remote Sensing studies were carried out using the relative band depth methods for the ASTER dataset for mapping talc and other associated minerals of the region. Principal Component Analysis (PCA), Independent Component Analysis (ICA), and Minimum Noise Fraction (MNF) were applied to the PRISMA dataset to map the lithology of the region. Along with that, the Spectral Angle Mapper (SAM) and Spectral Information Divergence (SID) algorithms map the talc and clay minerals using the PRISMA dataset. ALOS – 1 PALSAR dataset had been utilized to delineate the various lineaments present in the region at different angles. The obtained mineral maps form the ASTER had been validated with results of the PRISMA classified map and showed a good number of similarities. The obtained results from remote sensing have been further validated with the help of field survey and XRD analysis which confirms the presence of talc and clay minerals in the region. The structural pattern of the lineament shows the similarity in the direction orientation with the Jahazpur Thrust. Dolomites and clay minerals were mapped around the talc mining region which suggests that the alteration of these minerals played an important role in the formation of talc. Clay minerals were also mapped there and formed due to the weathering of the granites of Berach and Jahazpur present in the region. Both talc and clay deposits are present at the higher lineament density zones which represents the structural control over the mineralization. Therefore, the mineral deposits of the Jahazpur region are mineralogical and structurally controlled.

Barium titanate write-once read-many times resistive memory with an ultra-high on/off current ratio of 108

Write-once read-many times (WORM) resistive memories fabricated using perovskite barium titanate (BaTiO3, BTO) resistive switching (RS) layer are demonstrated in this study. The BTO RS layers with thicknesses of 3.2–8.5 nm are fabricated by radio frequency sputtering at room temperature. Annealing processes at 400–600 °C are used to modify the oxygen vacancy content in the BTO layer and thereby control the OFF-state current of an Al/BTO/n+-Si WORM device. The ION/IOFF ratio increases with increasing annealing temperature until 500 °C. A negative effect is observed when the temperature further rises to 600 °C. The optimal Al/BTO/n+-Si device shows an ultra-high ION/IOFF ratio of 108 and a low coefficient of variation of 6% for set voltages. The writing speed is 80 ns and the power consumption is 400 pJ. In addition, retention and stress tests are performed to confirm high data storage reliability of the device. Mechanisms for voltage-polarity independent writing process and the related energy band diagrams are explored.

Enhancing the production of adeno-associated virus (AAV)2 and AAV9 with high full capsid ratio in HEK293 cells through design-of-experiment optimization of triple plasmid ratio.

The recombinant adeno-associated virus (rAAV) vectors used in gene therapy are usually produced by transfecting three different plasmids (Adenoviral helper plasmid (pHelper), AAV rep/cap plasmids (pRepCap), and Transgene plasmid (pAAV-GOI)) into human embryonic kidney 293 (HEK293) cells. However, the high proportion of unwanted empty capsids generated during rAAV production is problematic. To simultaneously enhance the genome titer and full capsid ratio, the ratio of the three plasmids transfected into HEK293 cells was optimized using design-of-experiment (DoE). AAV2 and AAV9, which have different production kinetics, were selected as cell-associated and secreted model AAVs, respectively. In 125mL Erlenmeyer flasks, the genome titers of rAAV2 and rAAV9 at DoE-optimized plasmid weight ratios (pHelper:pRep2Cap2:pAAV-GOI=1:3.52:0.50 for rAAV2 and pHelper:pRep2Cap9:pAAV-GOI=1:1.44:0.27 for rAAV9) were 2.23-fold and 2.26-fold higher than those in the widely used plasmid weight ratio (1:1:1), respectively. In addition, compared with the plasmid ratio of 1:1:1, the relative VP3 band intensities of rAAV2 and rAAV9, which represent the relative empty capsid ratios, were reduced by 26% and 25%, respectively, at the DoE-optimized plasmid ratio. Reduced empty capsid ratios in the DoE-optimized plasmid ratios were also confirmed using transmission electron microscopy (TEM). Taken together, regardless of the AAV serotype, DoE-aided optimization of the triple plasmid ratio was found to be an efficient means of improving the production of rAAV with a high full capsid ratio.

Impact of surface treatments on the electron affinity of nitrogen-doped ultrananocrystalline diamond

In recent years, various forms of nanocrystalline diamond (NCD) have emerged as an attractive group of diamond/graphite mixed-phase materials for a range of applications from electron emission sources to electrodes for neural interfacing. To tailor their properties for different uses, NCD surfaces can be terminated with various chemical functionalities, in particular hydrogen and oxygen, which shift the band edge positions and electron affinity values. While the band edge positions of chemically terminated single crystal diamond are well understood, the same is not true for nanocrystalline diamond, which has uncontrolled crystallographic surfaces with a variety of chemical states as well as graphitic grain boundary regions. In this work, the relative band edge positions of as-grown, hydrogen terminated, and oxygen terminated nitrogen-doped ultrananocrystalline diamond (N-UNCD) are determined using ultraviolet photoelectron spectroscopy (UPS), while the band bending is investigated using photoelectrochemical measurements. In contrast to the widely reported negative electrode affinity of hydrogen terminated single crystal diamond, our work demonstrates that hydrogen terminated N-UNCD exhibits a positive electron affinity owing to the increased surface and bulk defect densities. These findings elucidate the marked differences in electrochemical properties of hydrogen and oxygen terminated N-UNCD, such as the dramatic changes in electrochemical capacitance.