Related Health Risks Research Articles

A Cross-Sectional Study On The Levels Of Knowledge About The Health-Related Risks Of Secondhand Smoke Exposure Among University Of Cyberjaya Students

Passive exposure to secondhand smoke (SHS) poses significant health risks, especially in areas where exposure is prevalent like Malaysia. Thus, addressing tobacco addiction and raising awareness about the dangers of smoking and SHS are critical, given the younger generation's perceptions and knowledge about these issues. The current study assessed the level of knowledge of University of Cyberjaya students about SHS-related risks, and then investigated the factors associated with knowledge. This is a quantitative cross-sectional study on the level of knowledge about health-related risks of secondhand smoke exposure among University of Cyberjaya students. The research was conducted for 12 months starting from 25/09/2023. The sociodemographics of the respondents and the smoking status were analysed using descriptive statistics. The significance between University of Cyberjaya students' level of knowledge on SHS-health-related dangers was determined using chi-square analysis. 371 respondents had completed the questionnaire. The result were that 70.35 % of the students in University of Cyberjaya had adequate level of knowledge while 29.65 % had inadequate knowledge. The study found no significant correlation between various sociodemographic factors and the level of knowledge about secondhand smoke (SHS) risks among University of Cyberjaya students, except for nationality, residency, housing, and academic year. This study indicates that students in University of Cyberjaya have adequate knowledge, regarding health-related risks of secondhand smoke exposure. Initiatives must be done to enhance the knowledge level of the remaining 29.65% of students with inadequate knowledge and this highlights considering specific demographic factors in efforts to enhance awareness of SHS-related health risks.

Promoting sustainable consumption and circular economy: the intention of Vietnamese youth consumers to purchase products made from recycled plastics

Recycling is viewed as a key component in a circular economy and serves as an ideal solution for promoting sustainability. During the global plastic crisis, plastic recycling practices have been adopted worldwide, leading to the production of various products made from recycled plastics (PRP). Nevertheless, a gap persists between consumption and demand for such products, which is primarily attributed to a lack of comprehension from the consumer perspective. Given the pivotal role consumers play in the adoption of these products, this study explores consumers’ intentions to purchase PRP. This is particularly significant in Vietnam, which is an emerging economy aspiring to achieve the objectives of a circular economy and sustainable development. Utilizing an integrated cognitive-emotional framework comprising the Valence Theory and the Norm Activation Model, data from 564 Vietnamese students were gathered and analyzed using structural equation modeling. The results show that awareness of consequences is a major driver of consumer purchase intentions, followed by perceived ease of application and monetary incentives. The results also indicate that health concerns have the strongest effect on purchase intention and in the negative side, meaning that the health-related risk is the primary concern for consumers during the decision-making process. This research holds substantial value for academics and managers, as it aids in the theoretical exploration and the formulation of strategies to improve consumer acceptance of PRP.

Differences in knee joint moments between individuals who are living with obesity and those of a healthy weight when negotiating stairs

BackgroundIndividuals who are living with obesity often adopt alternative lower limb walking mechanics compared to persons with a healthy weight. Stair negotiation is a common activity of daily living that, when used consistently with diet and other physical activity, can help promote the reversal of health-related risk factors associated with people who are obese. The purpose of this study was to determine how stair negotiation affects normalized and non-normalized peak knee extension and abduction moments in young adults who live with obesity (BMI between 30 and 40 kg/m2) compared to adults with a healthy weight (BMI between 18.5 and 25 kg/m2). MethodsFifteen young adults living with obesity and fifteen with a healthy weight performed stair ascent and descent walking trials on a 3-step instrumented staircase at a self-selected walking speed. A one-way ANCOVA (covariate: gait speed) was used to compare knee moment variables between groups. ResultsNo significant differences were found between groups in peak knee joint moments normalized to body mass. The individuals living with obesity demonstrated significantly larger non-normalized peak knee extension moments during stair ascent and descent but no differences in the non-normalized peak knee abduction moments for stair ascent or descent. ConclusionResults of this study indicate differences in non-normalized peak knee extension moments between BMI groups. The young age of the obese group may have contributed to minimal differences overall. Future research should determine how these findings differ in an older obese population and how using a handrail would affect these results.

Relative abundance and the fate of human rotavirus in wastewater during treatment processes: identification of potential infectious rotavirus in the final effluents and receiving aquatic milieu in Durban area, South Africa

The occurrence and persistence of rotaviruses in raw and treated wastewater and their discharge into rivers represent a significant health risk for humans and animals, worldwide. In this study, samples were collected monthly from each of the four Durban wastewater treatment plants (DWWTPs) and receiving rivers for a period of 3 months. Rotavirus was quantified by real-time quantitative PCR (RT-qPCR), and viability was assessed using integrated cell culture (ICC)-qPCR. Rotavirus was detected consistently in 100% of influent wastewaters (mean concentration range, 4.36–4.46 log10 genome equivalent (GE) copies/L) and final effluent samples of three DWWTPs (range, 3.35–3.61 log10 GE copies/L). Overall, 94% (45/48) of the wastewater analyzed and 95% (20/21) of the associated river water samples were positive for rotavirus (range, 2.04–6.77 log10 GE copies/L). The activated sludge process with 0.10–0.43 log10 reduction values (LRV) only moderately reduced the viral loads. Similarly, one of the DWWTPs that operated the biofilter modality produced 0.20 LRV. Though the additional treatment with chlorine produced higher LRV (range, 0.31–0.53) than the corresponding activated sludge or biofilter process, the difference in viral removals was not significant (p > 0.05). The equivalent treatment efficiencies of the four DWWTPs varied from 19 to 43% decay in the population of rotavirus. Further, infectious rotavirus ranging from 66.67 to 100%, 50 to 100%, and 66.67 to 100% were detected in the post-activated sludge, final effluents, and river water samples, respectively. In conclusion, the findings of infectious rotavirus in both the final effluents and associated rivers represent an infection risk for humans or animals during contact. Thus, close monitoring for rotavirus and risk assessment studies under distinct exposure scenarios may further shed light on the health-related risks associated with water recovery and reuse in urban settings.

Integrated RNA sequencing and biochemical studies reveal endoplasmic reticulum stress and autophagy dysregulation contribute to Tri (2-Ethylhexyl) phosphate (TEHP)-induced cell injury in Sertoli cells

Tri (2-Ethylhexyl) phosphate (TEHP), widely used as a fire retardant and plasticizer, has been commonly found in the environment. Its potential health-related risks, especially reproductive toxicity, have aroused concern. However, the potential cellular mechanisms remain unexplored. In this study, we aimed to investigate the molecular mechanisms underlying TEHP-caused cell damage in Sertoli cells, which play a crucial role in supporting spermatogenesis. Our findings indicate that TEHP induces apoptosis in 15P-1 mouse Sertoli cells. Subsequently, we conducted RNA sequencing analyses, which suggested that ER stress, autophagy, and MAPK-related pathways may participate in TEHP-induced cytotoxicity. Furthermore, we demonstrated that TEHP triggers ER stress, activates p38 MAPK, and inhibits autophagy flux. Then, we showed that the inhibition of ER stress or p38 MAPK activation attenuates TEHP-induced apoptosis, while the inhibition of autophagy flux is responsible for TEHP-induced apoptosis. These results collectively reveal that TEHP induces ER stress, activates p38, and inhibits autophagy flux, ultimately leading to apoptosis in Sertoli cells. These shed light on the molecular mechanisms underlying TEHP-associated testicular toxicity.

Job insecurity amid the COVID-19 pandemic and beyond: a systematic review and research agenda

PurposeThe catastrophic effects of the COVID-19 pandemic have considerably impacted the labour market and increased job insecurity among workers. This study systematically reviews the literature on job insecurity conducted in the context of the COVID-19 pandemic with three key objectives. First, to identify the key antecedents of job insecurity during the pandemic. Second, to identify the outcomes associated with job insecurity during the pandemic. Third, to identify the underlying boundary conditions that strengthened or alleviated the association between the antecedents of job insecurity and its associated outcomes.Design/methodology/approachThe study followed PRISMA 2020 guidelines for the selection and inclusion of scientific literature by systematically searching five electronic databases, namely, Scopus, ScienceDirect, PubMed, Web of Science and Psych Info.FindingsA perception of health-related risks, negative economic consequences and organizational restructuring during the pandemic were the primary factors contributing to job insecurity among workers. The consequences encompassed detrimental impacts on health and well-being, proactive measures undertaken by employees to alleviate the threat of job loss, and a variety of tactics employed to cope with stress arising from job insecurity. The boundary conditions elucidate the factors that alleviated job insecurity among workers and influenced both their work and non-work outcomes.Originality/valueThis is the first systematic review summarizing the literature on employees' experiences with job insecurity amid the COVID-19 pandemic. Based on a systematic review, this study provides doable steps that HR managers can take to effectively manage job insecurity among workers, particularly during a crisis.

Evaluating impacts of climate and management on reservoir water quality using environmental fluid dynamics code

Climate change and human interference, notably nutrient input, affect the water quality. Nitrogen (N) and phosphorus (P) are pivotal in managing eutrophication. This study investigated the effects of water dynamics and chemical constituents on water quality in Hongfeng Lake, a typical weakly stratified reservoir suffering from algae blooms in Southwest China, using the Environmental Fluid Dynamics Code. Leveraging climate, hydrological, and water quality data, we constructed, calibrated, and validated the temperature-hydrodynamics-water quality-sediment model. Various scenarios were analyzed, including wind speed, air temperature, solar radiation, rainfall, water discharge, N and P external input, and internal release. The findings revealed that no rain and warming increased trophic state index (TSI) and chlorophyll-a (Chl-a) concentration, and no solar radiation initially elevated nitrate concentration, followed by an increase in ammonium concentration. Besides, no solar radiation and changes in rainfall significantly increased total phosphate concentration. The management scenarios of N and P reduction, halving tributary, and mainstream flow scenarios improved water quality and reduced eutrophication. The wind speed under the N and P reduced scenarios showed that a doubling in wind led to increased concentrations of the particulate organic matter, Chl-a, and dissolved oxygen, alongside decreased ammonium and nitrate, while TSI exhibited minimal change. However, 5- and 10-times wind speed scenarios amplified TSI in shallow water, potentially due to a substantial rise in internal nutrient release. The degradation trend observed in drinking water quality amid climate change (warming and flooding) raises concerns regarding health-related risks. These simulations provided the quantified influence of climate change and environmental management strategies on water quality in the weakly stratified reservoir, notably highlighting the looming threat of exacerbated eutrophication due to warming, necessitating more stringent N and P reduction measures compared to current practices.

Indicators to complement global monitoring of safely managed on-site sanitation to understand health risks

Halfway through the Sustainable Development Goal (SDG) period, there has been little research on the criteria for monitoring safely managed sanitation under SDG target 6.2. For reporting against SDGs, global indicators are necessarily limited and exclude many safety aspects from a public health perspective. Primary survey data from 31,784 households in seven countries in Asia and Africa were analysed, comparing estimates of safely managed on-site sanitation based on global indicators with five complementary indicators of safety: animal access to excreta, groundwater contamination, overdue emptying, entering containments to empty and inadequate protection during emptying. Application of additional criteria reduced the population with safely managed sanitation by 0.4–35% for specific indicators, with the largest impact due to the risk of groundwater contamination, animal access, and containments overdue for emptying. Combining these indicators across the service chain, excluding transport and treatment, found almost three-quarters of on-site systems currently assessed as safely managed with global indicators were considered unsafe based on complementary indicators. A more comprehensive assessment of safety of on-site sanitation can be achieved through these indicators, which could be integrated into national monitoring systems and used to inform sanitation investments that address local health-related risks.

Screening for Health-Related Social Needs and Financial Toxicity Among Patients With Cancer Treated With Radiation Therapy: Findings From a Quality Improvement Project

IntroductionFinancial toxicity is common among patients with cancer, as are co-occurring health-related social risks (HRSRs). There is limited evidence to support best practices in screening for HRSRs and financial toxicity in the cancer context. This analysis sought to understand variations of identified needs based on treatment course using data from a large screening program. MethodsThis 2022 to 2023 screening quality improvement program included four services (breast, gastrointestinal, gynecologic, thoracic) at an urban comprehensive cancer center. The Comprehensive Score for Financial Toxicity measured financial toxicity. Patients completed an HRSR checklist documenting food, housing, medication, or transportation insecurity and financial borrowing practices. Differences were evaluated by treatment course (radiation therapy [RT] versus other treatment and RT plus chemotherapy versus other treatment). ResultsScreening surveys were sent to 70,983 unique patients; 38,249 completed a screening survey (54% response rate). Of responders, 4% (n = 1,686) underwent RT in the 120 days before their survey, and 3% (n = 1,033) received RT in combination with chemotherapy. Overall, patients receiving RT had lower unadjusted Comprehensive Score for Financial Toxicity scores, indicating worse financial toxicity. The proportion of patients receiving RT reporting unmet transportation (15% versus 12%, P < .001) and food (13% versus 11%, P = .02) needs was significantly higher than for patients not receiving RT. More patients receiving RT borrowed money than did patients not receiving RT (17% versus 15%, P = .02). In multivariable models, RT (alone or in combination) was associated with worse financial toxicity and transportation difficulties. ConclusionsScreening for financial toxicity and HRSR is possible at a large cancer center. Patients receiving RT have higher transportation insecurity and worse financial toxicity compared with those receiving other treatments. Tailored intervention throughout the treatment trajectory is essential.

Food Insecurity at a Large Academic Medical Center: Understanding the Five-Year Prevalence, Trends, Associated Health-Related Social Risks, and Requests for Assistance

Food Insecurity at a Large Academic Medical Center: Understanding the Five-Year Prevalence, Trends, Associated Health-Related Social Risks, and Requests for Assistance

Identifying and Addressing Health-Related Social Risks and Needs: Our Role

Identifying and Addressing Health-Related Social Risks and Needs: Our Role

The role of engaged living in the association between self-concealment and psychological distress among racially diverse college students in Hawaiʻi

Self-concealment has been identified as a significant risk factor for negative mental health outcomes. Engaged living, defined as the process of living one's life according to deeply held values with life fulfillment, is one salutary construct that may serve as a protective factor in light of mental health-related risk factors. The present cross-sectional study investigated whether engaged living moderated the positive association between self-concealment and psychological distress in a sample of 1,074 racially diverse college students in Hawaiʻi. Upon the completion of informed consent, study participants completed an online self-report survey that included the measures of interest in the present study. Results revealed that self-concealment was positively associated with psychological distress. Moreover, the strength of the positive association between self-concealment and psychological distress was smaller in participants with high (vs. low) levels of engaged living, but this moderating effect was small. A subsequent post-hoc analysis revealed that the indirect effect of self-concealment on psychological distress manifested through engaged living. Conceptual and applied implications of the present findings, as well as future directions of this line of inquiry, are discussed.

Determination of Heavy Metal Concentrations on some Selected Herbal Medicinal Preparations Marketed in Kano State, Nigeria

Study’s Novelty/Excerpt This study assesses heavy metal concentrations in traditional medicinal herbs consumed in Kano State, Nigeria, providing critical insights into their relative safety and potential health risks. By analyzing ten powdered herbal samples using Atomic Absorption Spectrometry, the research identifies concerning levels of lead, chromium, cadmium, and mercury, with lead concentrations in one sample exceeding the WHO's safety limits. The findings highlight significant variability in heavy metal content among different herbs, underscoring the need for stringent quality control and regulatory measures to ensure consumer safety. Full Abstract Herbs are extensively consumed in Nigeria, for their medicinal properties and availability. This study aimed at determining the concentration of heavy metals residues in some selected traditional medicinal herbs consumed in Kano State, Nigeria. This is to assess their relative safety and potential health risks to local inhabitants based on the World Health Organization standard limit. A total of ten (10) powdered samples of medicinal preparations were purchased from local markets in Kano metropolis and analyzed for the presence of lead, chromium, cadmium, and mercury contents. The samples underwent digestion, and heavy metal concentrations were determined using Atomic Absorption Spectrometry (AAS). The metals found to be present varied in different concentrations in the herbal samples. The presence of heavy metal ranges as follows: 0.6-6.5mg/kg for chromium, 3.10-22.10mg/kg for lead, 0.08-0.60mg/kg for cadmium, and 0.09-0.30mg/kg for mercury. However, mercury content was not detected in some samples. The study's findings conclude that the lead (Pb) values were found to be the highest in concentration, exceeding the W.H.O limits in sample J, which is used as a remedy for cough. This indicates that the sample is highly contaminated compared to others. Mercury was not detected in four of the samples, and when present, it was below the limits set by the World Health Organization, making all the samples free from mercury contamination.

Quality evaluation and health risk assessment of karst groundwater in Southwest China

Groundwater in karst regions is of immense value due to its vital support for regional ecosystems and residents' livelihoods. However, it is simultaneously threatened by multi-source pollution from agricultural non-point sources, industrial and domestic point sources, and mining activities. This study focuses on the Guangxi of China, which features typical karst topography, aiming to thoroughly assess the groundwater quality and related health risks in Guangxi, especially identifying the impacts of various key pollution sources on the groundwater environment. A total of 1912 groundwater samples were collected, covering an area of approximately 237,600 km2. The spatial distribution of pollutants was analysed using the Nemeroww index method and Kriging interpolation, while multivariate statistical and cluster analysis methods were employed to identify the main types of pollution sources. Furthermore, based on the human health risk assessment model of the U.S. Environmental Protection Agency (US EPA), a risk assessment was conducted for key pollutants. The results revealed widespread heavy metal contamination in Guangxi's groundwater, particularly with concentrations of Mn, As, Al, Pb reaching up to 9.4 mg/L, 2.483 mg/L, 37.95 mg/L, 4.761 mg/L, respectively, significantly exceeding China's national Class III groundwater quality standards. Cluster analysis indicated that mining and industrial activities are the primary sources of pollution. The health risk assessment demonstrated that these activities pose a significant risk to public health. The aim of this study is to provide a scientific basis for the protection of the groundwater environment in Guangxi and other karst areas, the formulation of pollution prevention and control strategies, and the optimization of urban and industrial land use layouts. Future research should focus on advanced isotopic and molecular biological techniques to trace pollution sources more precisely and evaluate the effectiveness of pollution control measures.

QPCR assay optimisation for a clinical study comparing oral health risk in Rett syndrome

PurposeThis study aimed to validate qPCR assays for specific microbiota, for use on dental plaque samples stored on Whatman FTA cards to compare relative oral health risk in Rett syndrome.MethodsSupragingival dental plaque samples were collected, using a sterile swab, (COPAN FLOQswab™) swabbed onto Whatman FTA™ cards. DNA extraction was performed using a modified Powersoil™ protocol. Where published assays were unsuitable, species-specific qPCR assays for caries-associated, gingivitis-associated and oral-health-associated bacteria were designed using multiple sequence alignment, Primer3Plus and PrimerQuest. Assays were run using absolute quantification. Limit of detection (LOD) and limit of quantification (LOQ) were calculated, and PCR products verified by Sanger sequencing.ResultsMost assays allowed detection using real-time qPCR with high specificity on samples collected on FTA cards. Several assays showed low or even single gene copy numbers on the test samples.ConclusionAssays were optimised for detection and evaluation of oral health risk in dental plaque samples stored on FTA cards when cold storage is not feasible, except for F. nucleatum. Several assays showed gene copy numbers less than the LOQ or outside the range of the standard curve, so there is merit in optimising these assays using digital droplet PCR.

Impacts of unregulated dumpsites: a study on toxic soil contamination, associated risks, and call for sustainable environmental protection in Nnewi, Nigeria

The accumulation of leachates from unlined dumpsites laden soil-water environment with toxic elements poses imminent threats to both the environment and humans. This study evaluated the seasonal levels of potentially toxic elements (PTEs), their health-related risks, contamination factors (CF), pollution load index, geo-accumulation index (Igeo), ecological risk index, polymetallic contaminant index and Nemerow's synthetic pollution index of soils near a waste dump in Nnewi, Anambra State, Nigeria. The PTE results indicated that levels of Cd (1.54–3.40 mg/kg) were above the World Health Organization's threshold limit for soil. The studied soil samples had PTE levels higher than the control samples due to their proximity to the dumpsite. The CF of the PTE in the soil indicated moderate to considerable contamination, while the control areas showed moderate contamination for both seasons. The pollution load indices of the soil indicated heavy and moderate pollution for the study sample (2.207–2.517) and control samples (1.445–1.659). However, the ecological risk indices ranged from 85.72 to 164.84, indicating a low ecological risk. The Igeo of the PTE in the soil ranged from unpolluted, moderately polluted to very strongly polluted. The Nemerow's synthetic pollution index values ranged from 3.560 to 3.564 for the study samples and 2.070–2.502 for the control samples, indicating heavy and moderate pollution of the soil respectively. The polymetallic contaminant index values for the study samples (23.22–26.43) and control samples (15.02–17.23) showed high and considerable contamination respectively. Health risk examination highlighted that both adults and children have a low risk for non-cancer health threat via ingestion route, while a high risk was obtained for children for cancer health dangers via ingestion routes. For the dermal pathway, children and adults have minimal chances of exposure to cancer risks, while a high exposure to non-cancer risk was observed for children. Pearson's correlation and principal component loadings revealed the sources of pollution to be of similar origins linked to anthropogenic activities. Awareness programs are necessary to educate the populace about the dangers of using contaminated soil for farming or recreational activities. The use of sanitary dumpsites should be encouraged and adopted as a waste disposal method by the government to mitigate the spread of PTE into the environment.

Impacts of the COVID-19 pandemic on the mental health of frontline hospital-based nurses: rapid review and meta-analysis

The COVID-19 pandemic focused the world’s attention on the gross relative health risks, inequities and injustices experienced by first responders, of whom front-line, hospital-based nurses may be the most vulnerable. A series of research syntheses prior to the pandemic estimated that such front-line nurses were at approximately two-fold greater risk of experiencing mental health challenges such as increased symptoms (and diagnoses) of anxiety, depression and PTSD than were nursing administrators or otherwise similar, people in the general population. Aiming to clarify how the pandemic impacted such mental health risks, we conducted a rapid review and meta-analysis of observational studies from the worldwide published and gray research literature. Twelve longitudinal studies that covered the pandemic’s pre-vaccination phase were included. The overall pooled increased relative risk of mental health challenges among frontline, hospital-based nurses from pre-pandemic to the pre-vaccination phase of the COVID-19 pandemic was 2.62 (95% CI 2.10, 3.27). But sensitivity and moderator analyses accounting for research design limitations better estimated two-fold increased risks (relative risks ranged from 1.69 to 2.00). Already at elevated risk of experiencing symptoms of anxiety, depression and PTSD and so, such increased symptoms and diagnoses among front-line, hospital-based nurses probably doubled during the early, pre-vaccination phase of the pandemic, perhaps quadrupling among women. Implications for nursing practice, health care policy, future pandemic preparedness as well as future research are discussed.

Evaluating the seasonal variations of risks associated with potentially toxic elements in underground water sources near a dumpsite in Awka, Nigeria

Contamination of borehole water by leachates from dumpsites has significantly affected the health of those who use polluted water for domestic activities. This study evaluated the seasonal variations of risks associated with potentially toxic elements in underground water sources near a dumpsite in Awka, Nigeria. The levels of the potentially toxic elements (PTEs) were compared with the World Health Organization (WHO) and Nigerian standard for drinking water quality (NSDWQ) standard limits. The, sources of PTEs, metal pollution index, water quality index, ecological risk, and health-related risks of using the underground water were evaluated. The chemical results indicated that levels of Cd and Pb were above the WHO and NSDWQ threshold limits for potable water. The Mn and Ni values were above the NSDWQ limits for potable water. The study borehole samples had PTE levels higher than the control samples due to their proximity to the landfill. The water quality index ranged from 1290.29 to 2243.04, showing that the water is unsuitable for drinking and other domestic uses. The metal pollution indices of the underground water samples were above 1, indicating that the water needs treatment before use. The health risk examination highlighted that children are more disposed to non-cancer risk than adults based on the hazard indices obtained. Also, the probability of cancer risks was high, showing that both children and adults are likely to be in danger of cancer risks. However, the ecological risk indices ranged from 11.187 to 51.581, indicating a low ecological risk. Pearson's correlation and principal component analysis revealed that the sources of pollution are from similar origins/sources linked to anthropogenic activities. Awareness programs are necessary to educate the populace about the dangers of using contaminated water. Effective waste management strategies and water treatment techniques should be implemented.

Higher adiposity predicts greater intra-individual inconsistencies in postprandial glycemic measurements-an analysis of three randomized controlled trials in Asian populations.

Acute glycemic responses offer important insights into glucose homeostasis although the repeatability of these measurements particularly in Asian populations remains unclear. This research aimed to critically investigate the inconsistencies of the postprandial glycemic profile within individuals, and identify potential variables predicting greater inconsistencies. This was a secondary analysis of three randomized controlled trials which fed subjects with glucose (and other carbohydrate-rich foods), and measured postprandial blood glucose at regular intervals. Intra-individual rank-order consistency in the glycemic profile between acute glucose treatments was evaluated and compared against demographic, anthropometric and cardio-metabolic health related indicators to delineate potential confounding variables. Correlations between the incremental area under curve at 120 min (iAUC120 min) for glucose and the carbohydrate-rich foods were further explored. Rank-order consistency was identified to be moderate, with intra-individual inconsistencies marginally lower than inter-individual inconsistencies. Notably, greater inconsistencies within individuals were directly correlated with BMI and fat-mass index (P < 0.01) albeit non-significant for age, ethnicity, and other cardio-metabolic health-related risk indicators. Across the trials, there were positive monotonic correlations between the iAUC120 min for glucose and simple sugars (sucrose, isomaltulose), as well as different varieties of rice (jasmine white, Bapatla brown, Bapatla white; p < 0.05). However, there were a lack of associations between iAUC120 min for glucose with pastas (semolina and wholegrain penne, spaghetti) and mee pok noodles. There are inherent inconsistencies in postprandial glycemic measurements within individuals, particularly among those with higher adiposity. These confounders need to be kept in mind for appropriate and meaningful interpretations of glycemia.

Tobacco cessation - the underused potential in clinical routine

Tobacco control, psychosocial and medical assistance regarding tobacco cessation is still a hidden potential within the German health care system. So far doctors rarely talk to their patients about their smoking status and physical and psychological benefits of quitting.This paper focusses on recommended current diagnostic and treatment standards, as well as evidence-based methods to address the topic on how to stop smoking and its association with certain diseases such asCOPD,lungcancer and COVID-19 infection. The role of e-cigarettes as a cessation tool and its health related risks are critically examined. Consequences and advice how to implement smoking cessation procedures into daily practice are presented.