Regulatory Effect Of Acupuncture Research Articles

Quality of the Evidence Supporting the Role of Acupuncture Interventions for Vascular Dementia.

Inflammation is an important pathogenesis of vascular dementia (VaD), and the regulatory effect of acupuncture on neuroinflammation has received extensive attention. There is conflicting evidence regarding the efficacy and safety of acupuncture for postpartum VaD. This overview aims to systematically evaluate systematic reviews/meta-analyses (SRs/MAs) of acupuncture on VaD. From the establishment of the electronic database to August 2022, search and identify SRs/MAs on acupuncture treatment for VaD. The Assessing the Methodological Quality of Systematic Reviews 2 (AMSTAR-2), the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 (PRISMA 2020), and the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system were used to evaluate the methodological, reporting, and evidence quality of the included SRs/MAs. Twelve SRs/MAs were included in this research, and the quality of methodological, reporting, and evidence for these SRs/MAs were not satisfactory. The shortcomings of these SRs/MAs mainly include lack of protocol registration, incomplete literature search, missing list of excluded literature, and high risk of bias of included original clinical trials. VaD patients may benefit from acupuncture therapy. However, the high risk of bias in original clinical trials and the low quality of SRs/MAs make evidence-based decisions less reliable.

Regulatory effect of acupuncture on electrical activity level of optic cortex in amblyopia model rats

Regulatory effect of acupuncture on electrical activity level of optic cortex in amblyopia model rats

Role of serotonin signaling system in gastrointestinal tract: Implications for regulatory effect of acupuncture and moxibustion on irritable bowel syndrome

Role of serotonin signaling system in gastrointestinal tract: Implications for regulatory effect of acupuncture and moxibustion on irritable bowel syndrome

Thinking on functional mechanism of acupuncture for inflammatory bowel diseases based on Metabolomics

Acupuncture has a good therapeutic effect in treatment of inflammatory bowel diseases (IBD), but its functional mechanism has not been systematically explained. Metabolomics is the scientific study of dynamic chemical processes involving metabolites as well as metabolic response of living organisms. Metabolomics, a research method with integrity and dynamics, corresponds to the overall regulatory effect of acupuncture and is in line with the overall concept of traditional Chinese medicine (TCM) and the concept of homeostasis. In the recent years, metabolomics has been extensively applied to the clinical and experimental study of IBD, and its potential applied value has been unanimously acknowledged by the researchers. In this article, the application status of metabolomics in acupuncture is summarized, and the research ideas to study the mechanism of acupuncture in the regulation and control of IBD by metabolomics are preliminarily explored.

Acupuncture modulates the neuro-endocrine-immune network

As a nonspecific physical stimulation, the effect of acupuncture on diseases is produced by motivating the inherent regulatory system in the body, having the characteristics of whole regulation, dual directional regulation, etc. Modern scientific researches show that body's inherent regulatory system is neuro-endocrine-immune (NEI) network. Hence, we speculate that the regulatory effect of acupuncture may be produced through its regulation of NEI network. In this article, we reviewed the recent researches about acupuncture's effect on the NEI network, to find out the evidence of acupuncture adjusting NEI network and provide some evidences for revealing the mechanism of acupuncture.

Effect of acupuncture on rabbit bladder with urodynamic indexes

ObjectiveTo study the effect of acupuncture on rabbit bladder with urodynamic indexes. MethodsNew Zealand male rabbits were divided into control group, model group, treatment group 1 treated by acupuncture at Shenshu (BL 23) and treatment group 2 treated by acupuncture at Zhongji (CV 3). The urine dynamic parameters through the urethral catheter were detected in each group in order: fluctuation of pressure at filling phase of urinary bladder and flow rate in urination phase, which were used as quantification indexes of urinary bladder function. The urinary bladder abnormal model was prepared by administration of cholinergic stimulant; Regulatory effects of acupuncture at Shenshu (BL 23) and Zhongji (CV 3) on the abnormal state of the urinary bladder were respectively observed. Results1) In the filling phase of urinary bladder and in the urination phase, the intravesical pressure wave in infilling (IPWI) and intravesical discharge rate (IDR) could be respectively recorded. 2) IPWI and IDR could become abnormality by neostigmine methyl sulfate [stability type IPWI: the control group (n=20, 80%) vs the model group (n=15, 14.3%), P<0.01; IDR and time regression equation: the control group (n=20, y=24.3 – 0.878x) vs the model group (n=15, y=40.0 – 5.15x), P<0.01]. 3) Abnormal IPWI's could be normalized respectively by acupuncture at Shenshu (BL 23) and Zhongji (CV 3) [the stability type IPWI wave: the model group (n= 2, 14.3%) vs the treatment group 1 (n=3, 30%), P> 0.05; the instability type IPWI wave: the model group (n=13, 85.7%) in vs the treatment group 2 (n=6, 60%), P>0.05]; 4) Abnormal IDR also could be turned to normality by acupuncture at Shenshu (BL 23) and Zhongji (CV 3), respectively [IDR and the time regression equation: the model group (n=15, y=40.0 – 5.15x) vs the treatment group 1 (n=10, y= 18.9 – 0.499x), P<0.01; the model group (n=15, y= 40.0 – 5.15x) vs the treatment group 2 (n=10, y= 17.5 – 0.251x), P<0.01]. Conclusion1) Urodynamic indexes can be used for study of mechanism of acupuncture effects; 2) The effect of acupuncture in the bladder filling phase is smaller than that in the urination phase; 3) Acupuncture has a very obvious effect on intravesical discharge rate.

Tnfα Theory for the Beneficial Effects of Acupuncture on Infantile Colic: Formula-Fed Infants and Probiotic Treatments

In an earlier article,1 I proposed a theory and described the supporting evidence for the pathways for the possible influence of tumour necrosis factor α (TNFα) on maternal breast milk and its influence on the pathophysiology of infantile colic. I emphasised how the increased TNF levels of a breastfeeding mother affect TNF, melatonin and serotonin levels of a colicky baby, and examined evidence for the direct and indirect regulatory effects of acupuncture over TNFα, serotonin and melatonin levels, and thereby infantile colic. In a commentary on my paper,2 Reinthal et al stated that ‘Even if TNFα does play a …

Progress in understanding mechanisms underlying the regulatory effect of acupuncture on functional constipation

Progress in understanding mechanisms underlying the regulatory effect of acupuncture on functional constipation

Influence of acupuncture on insulin resistance in simple obesity patients

Objective To investigate the regulatory effect of acupuncture on insulin resistance in simple obesity patients and its clinical effect.

Regulatory effect of acupuncture and moxibustion on the hematopoiesis of leukopenia model in rats

Objective: To investigate the effect of acupuncture or moxibustion at acupoint Geshu (BL 17) on raising leukocyte and promoting marrow proliferation.Method: Wister rats were selected to established the leukopenia and immuno-suppression model by intraperitoneal injection of cytoxan (CTX). After they were grouped and treated, leukocyte and marrow karyocyte were counted in different phases to evaluate the effect of acupuncture or moxibustion at acupoint Geshu (BL 17) on raising leukocyte and promoting marrow hematopoiesis.Results: Acupuncture or moxibustion at acupoint Geshu (BL 17) and routine western medicine could all significantly raise leukocyte and increase marrow karyocyte. The currative effect was better in moxibustion group than in acupuncture group and in routine western medicine group (P<0.05).Conclusion: Moxibustion at acupoint Geshu (BL 17) can markedly raise peripheral blood leukocyte and marrow karyocyte of the leucopenia model in rats.

Effect of acupuncture on immunoglobulins of serum, saliva and gingival sulcus fluid.

The present research is a preliminary investigation of the changes of immunoglobulins in serum, saliva and gingival sulcus fluid in response to acute and chronic acupuncture stimulation in 70 volunteers. The acute effect of acupuncture showed that 30 minutes and 24 hours after acupuncture treatment saliva IgA levels were significantly increased in those who had previous low levels of IgA, but decreased in those who had previous high levels. When acupuncture was given daily for 2 weeks, the saliva IgA level was significantly increased, about 20% higher than that of the initial value. The IgG levels in serum and gingival sulcus fluid were decreased at 30 minutes after acupuncture treatment. On the other hand, chronic acupuncture stimulation (daily for 7-10 days) significantly increased IgG levels in both serum and gingival sulcus fluid. The regulatory effect of acupuncture on the immunological function of body defense system is discussed.