ABSTRACT Micro-, small, and medium-sized enterprises (MSMEs) are crucial to the Indian economy, significantly contributing to employment, industrial output, and regional development. As of March 2024, India hosts approximately 40 million MSMEs, predominantly micro-enterprises, which together account for around 30 percent of Gross Domestic Product and employ over 110 million people. This article explores the multifaceted role of MSMEs, examining their distribution across manufacturing, trade, and services sectors. The manufacturing segment, including textiles and food processing, employs about 31 percent of the MSME workforce, while trade and services sectors contribute 33 percent and 36 percent, respectively. The study reviews financing mechanisms, government policies, and human capital development, assessing the MSME sector’s resilience and adaptability in the face of economic disruptions and policy changes. Linear regression analysis reveals stability in manufacturing, fluctuations in trade, and consistent growth in the services and electricity sectors. Despite the MSME sector’s significant contributions, MSMEs face challenges, such as limited access to finance, regulatory complexity, and technological gaps. Opportunities for growth include digital transformation, export expansion, and enhanced government support. Addressing these challenges through improved credit facilities, technological support, regulatory reforms, and infrastructure development is essential for sustaining MSME growth and competitiveness. The World Congress on MSMEs underscores the need for comprehensive policy frameworks to support the MSME sector’s ongoing development and their role in driving economic progress and regional development.