Regular Hospital Visits Research Articles

Telemedicine and telehealth

Regular hospital visits can be expensive due to travel costs, especially in rural areas. Fortunately, when telemedicine services are used through video conferencing or other virtual technologies, doctor visits can be reduced. Therefore, telemedicine saves the patient and the medical staff time and treatment costs. In addition, with its fast and efficient operations, it can simplify the workflow of hospitals and clinics. This innovative technology makes it easier to monitor discharged patients and manage their recovery. In conclusion, it is enough to say that telemedicine can create a win-win situation. The purpose of this article is to examine the main trends, treatment workflow characteristics, and barriers to the use of telemedicine in healthcare. As a new technology, telemedicine is preferred by large hospitals. With the development of Internet technology, digitization and information have been applied to telemedicine, but telemedicine still has many limitations due to many factors. This article summarizes the evolution of telemedicine. The development of telemedicine at home and abroad was discussed. The use of telemedicine was explored including the feasibility and limitations of commercialization and development. and provide a vision for the integration of these technologies into the medical field has resulted in the telephone, which is now available worldwide. This article presents telemedicine in three main areas, including current status, challenges and opportunities based on research and implementation. he integration of these technologies into the medical field has resulted in the telephone, which is now available worldwide. This article presents telemedicine in three main areas, including current status, challenges and opportunities based on research and implementation.

Factors related to self-care in Korean patients with tuberculosis: A systematic review and meta-analysis.

Tuberculosis (TB) remains a major public health challenge in South Korea which has one of the highest TB incidence rates among the Organisation for Economic Co-operation and Development (OECD) countries. Effective self-care, including medication adherence and regular hospital visits, is crucial for successful TB treatment and the prevention of drug resistance. TB self-care in South Korea is influenced by cultural, social, and systemic factors. This study aimed to systematically review and conduct a meta-analysis of factors influencing self-care among Korean patients with TB, providing evidence-based insights for developing effective self-care promotion programs. A systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, focusing on quantitative studies published since 2000 involving Korean patients with TB. Twenty studies were included in the final analysis, and 44 factors related to self-care were categorized into sociodemographic, TB-related, psychological, environmental, and educational characteristics. Effect sizes were calculated using Comprehensive Meta-Analysis (CMA) 4.0, with the assessment of heterogeneity and publication bias. The meta-analysis ranked the effect sizes of the different characteristic categories as follows: environmental > educational > psychological. Among the individual factors, social support had the greatest influence on self-care, followed by quality of life, self-efficacy, nonfamily support, family support, and perceived health benefits. These findings underscore the critical role of sustained social support from the community, medical staff, and family in enhancing self-care among TB patients. Effective self-care strategies for patients with TB should focus on interventions that strengthen the environmental, educational, and psychological aspects. These findings suggest that similar approaches can be applied in other countries facing comparable healthcare challenges. This study acknowledges limitations including potential publication bias and the exclusion of older studies and non-Korean patient studies, highlighting the need for further research across diverse settings and populations.

Factors Of Accidental Falls Among In Elderly Living Alone In Phetchaburi Province Thailand

This research was to study the factors of accidental falls among elderly living alone. The researcher conducted a mixed methods research (Mixed Methods Research) to study factors affecting the incidence of falls and falls in elderly people who live alone. The research results found that Factors that result in falls and falls in elderly people who live alone. Phetchaburi Province has a total of 5 main factors and 24 sub-factors, consisting of main physical factors. Sub-factors were eye disease (p = 0.001, β =1.063), osteoarthritis (p = 0.001, β = 0.955), urinary system intelligence (p = 0.001, β =1.588), frequently going to the bathroom at night (p = 0.001, β =1.236) Congenital disease (p = 0.001, β = 1.638) Regular hospital visits (p = 0.001, β = 1.494) Main behavioral factors Sub-factors include taking medicine to treat chronic diseases (p = 0.001, β = 2.959), using alcoholic beverages (p = 0.001, β = 4.014), not exercising (p = 0.001, β = 5.350), wearing comfortable shoes. Inappropriate (p = 0.001, β = 2.723) Inappropriate clothing (p = 0.001, β = 3.574) Main environmental factors Sub-factors: regularly using stairs (p = 0.001, β = 3.354), two-story house (p = 0.001, β = 4.571), split-level house (p =0.001, β = 2.296), light switch not nearby. mattress (p = 0.001, β =2.363) main economic and social factors The sub-factor was frequently attending social events (p = 0.001, β = 6.633), missing home visits from the health service unit (p = 0.001, β = 3.916). The main factor was caregiver. The sub-factor is living with offspring (p = 0.001, β = 6.019 ) and having to live alone (p =0.001, β = 1.002 ).

435-P: Prediabetes and Cardiovascular Disease (CVD) Risk—Insights from a Large-Scale Japanese Cohort Investigating the Impact of Regular Hospital Visits

435-P: Prediabetes and Cardiovascular Disease (CVD) Risk—Insights from a Large-Scale Japanese Cohort Investigating the Impact of Regular Hospital Visits

Social networks and social support: Parents experiences in the management of thalassemia, a complex lifelong inherited blood disorder, in the indigenous context – A qualitative study

BackgroundThalassemia is the most serious and rare genetic blood disorder and requires regular blood transfusions and lifelong medical care. Indigenous people living in low –and middle-income countries have limited opportunities and support to access and receive services. AimThe present study aimed to uncover the social networks of affected indigenous families and their role in the treatment and management of the disease from the perspective of the parents of affected children. Materials and methodsParticipants included parents of children who provide care and support for their children to receive regular treatment. This qualitative study used a phenomenological approach and collected data through in-depth face-to-face interviews to understand the parent's lived experiences in an indigenous context. Participants' demographic data and network members were collected, and the network map was depicted using NodeXL software. Thematic analysis was used to extract important themes from the data. Themes extracted during analysis indicated that families with homogenous extended families, neighbors, and relatives received tangible social support such as blood donation, caring for the affected, and regular hospital visits. ResultsFamilies with heterogeneous peer families, non-governmental organizations (NGO), religious organizations, and tertiary care professionals availed of Government schemes and services and achieved permanent bone marrow transplantation cures. ConclusionThese findings are significant for developing a context-specific strategy to provide genetic treatment and service delivery, which is crucial for managing hereditary diseases.

Cancer Screening Abstinence Rates and Rationales Among Regular Outpatients at a Rural Hospital in Japan: A Cross-Sectional Study.

This study aimed to investigate cancer screening rates and the reasons for not undergoing screening among patients who regularly visited the Sanmu Medical Center. This prospective observational study recruited patients aged ≥40 years with regular clinic visits to Sanmu Medical Center during October 2019. We conducted a self-administered survey to determine the patient's sex and whether they underwent cancer screening in 2019, and if not, the reason for the same. The primary outcome measure was the percentage of people who did not undergo cancer screening. A total of 198 responses (108 male respondents) were obtained. Among them, 189 were valid responses (valid response rate 94.5%). One hundred and twenty-nine patients (68.2%, 76 male) had not undergone screening. The most common reasons provided were "I have regular regular clinic visits and do not think they are necessary" (N = 65, 50.3%), "I underwent a gastroscopy within 2 years, a colorectal camera examination within a few years, and a chest radiography within a year" (42.5%), and "I have a separate complete medical checkup" (N = 15, 11.6%). Of the 65 patients who responded that their cancer screenings were unnecessary, 42 patients (64.6%) had not undergone a gastroscopy within 2 years, a colorectal camera examination within a few years, or a chest radiography or examination within a year. Roughly half of the respondents who did not undergo cancer screening elected to abstain because they believed that regular hospital visits were sufficient. Encouraging patients who regularly visit medical institutions to receive cancer screening is therefore necessary.

A qualitative study on perceptions and practices of diabetes prevention and management in rural south India

Abstract Aims: The purpose of this study is to explore the perceptions and practices of diabetes management through focus group discussions (FGDs) among adults with diabetes in rural Tamil Nadu. Materials and Methods: A qualitative study was conducted among individuals with diabetes who were part of the Telemedicine pRoject for screENing Diabetes and its complications in rural Tamil Nadu (TREND). A total of 16 FGDs were conducted using a semi-structured FGD guide that elicited perceptions of the different aspects of diabetes management and knowledge about diabetes prevention. The sample size was based on the attainment of thematic saturation. All FGDs were audio-recorded and transcribed verbatim. The textual data was then coded into meaning units and grouped into themes. Data were analyzed using NVIVO software version 10.0. Results: There were varied responses with respect to diet, medication adherence, regularity of follow-up, knowledge about diabetes, and diabetes prevention. Most participants had limited knowledge of the disease and did not have regular hospital visits. Several participants were unable to adhere to the diet prescribed by healthcare providers, as they lived alone or were dependent on someone in the family for dietary needs. Most participants were unaware that diabetes could be prevented. Some participants were interested in serving as “Diabetes ambassadors” to educate rural societies about diabetes. Conclusions: Understanding the perceptions and practices about diabetes management and prevention strategies could help primary healthcare workers effectively treat, manage, and prevent diabetes in underserved rural populations.

Transcutaneous Electrical Stimulation of the Abdomen, Ear, and Tibial Nerve Modulates Bladder Contraction in a Rat Detrusor Overactivity Model: A Pilot Study.

The global prevalence of overactive bladder (OAB) is estimated at 11.8%. Despite existing treatment options such as sacral neuromodulation, a substantial number of patients remain untreated. One potential alternative is noninvasive transcutaneous electrical stimulation. This form of stimulation does not necessitate the implantation of an electrode, thereby eliminating the need for highly skilled surgeons, expensive implantable devices, or regular hospital visits. We hypothesized that alternative neural pathways can impact bladder contraction. In this pilot study, we conducted transcutaneous electrical stimulation of the abdominal wall (T6-L1), the ear (vagus nerve), and the ankle (tibial nerve) of 3 anesthetized female Sprague-Dawley rats. Stimulation was administered within a range of 20 Hz to 20 kHz, and its impact on intravesical pressure was measured. We focused on 3 primary outcomes related to intravesical pressure: (1) the pressure change from the onset of a contraction to its peak, (2) the average duration of contraction, and (3) the number of contractions within a specified timeframe. These measurements were taken while the bladder was filled with either saline or acetic acid (serving as a model for OAB). Transcutaneous stimulation of the abdominal wall, ear, and ankle at a frequency of 20 Hz decreased the number of bladder contractions during infusion with acetic acid. As revealed by a comparison of various stimulation frequencies of the tibial nerve during bladder infusion with acetic acid, the duration of contraction was significantly shorter during stimulation at 1 kHz and 3 kHz relative to stimulation at 20 Hz (P = 0.025 and P = 0.044, respectively). The application of transcutaneous electrical stimulation to the abdominal wall, ear, and tibial nerve could provide less invasive and more cost-effective treatment options for OAB relative to percutaneous tibial nerve stimulation and sacral neuromodulation. A follow-up study involving a larger sample size is recommended.

A refugee mother's perspective: Healthcare satisfaction and access to health services as an immigrant in Turkiye.

The civil war that broke out in Syria in 2011 caused 3.7 million Syrians to migrate to Turkiye. Being particularly vulnerable women refugees may experience problems with access to healthcare services. This study aimed to determine the health problems of refugees in Ankara, their access to and use of these services. Healthcare-related levels of refugee mothers were assessed using a questionnaire and the study was conducted with the participation of 310 refugee mothers who presented to the Refugee Health Center, between 15 September 2017 and 15 December 2018. Among the participants, 28.4% were minors who were between the ages of 15 and 18 years. The mean age of the mothers was 31.18±13.84 years, while the mean age of the fathers was 32.37±10.76 years. During their residence in Ankara, the participants preferred Refugee Health Centers (94%) and State Hospitals (83%) for healthcare. Of the participants, 42.1% stated that one or more family members had health problems, which necessitated regular hospital visits. In this study, 95.2% of participants stated that they were satisfied with the healthcare services they were receiving. Although state hospitals were frequently used, refugees were also able to find solutions to their health problems through Refugee Health Centers. Nevertheless, while using other healthcare institutions, the biggest issue for the refugees was the language barrier. The high rates of adolescent pregnancy, disabilities, and chronic diseases were found to be among the main health problems of refugees. Women refugees seemed disadvantaged in education, language, income and employment.

Psychopathological Symptoms Among Chronically Ill Patients During SARS-CoV-2 Pandemic in Poland.

IntroductionThe global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic had a drastic psychological and economic impact on the global population. Having a chronic disease during the pandemic is associated with numerous limitations and challenges like regular hospital visits, access to health-care units and getting specialized treatment. In addition, chronically ill patients are at great risk of acquiring the SARS-CoV-2 virus and at experiencing a more severe course of illness, due to comorbid conditions as well as more frequent encounters with health-care workers and other patients in medical facilities. The aim of this study was to examine the psychological disturbances, during the pandemic in chronically ill patients.MethodsDuring the cross-sectional survey conducted between May and October 2020, 398 patients with four different chronic conditions (psoriasis, multiple sclerosis and patients who have undergone a kidney transplant or received dialysis). Study sample was examined regarding the occurrence of psychopathological symptoms (General Health Questionnaire 28) and their perceived stress levels (Perceived Stress Scale).ResultsThe highest scores were found in the MS group and the lowest scores were found in the kidney transplantation group in every subscale of the GHQ-28. Close to half of the studied population (48.74%, n = 193) patients scored above the cut-off for psychopathology.ConclusionAs the study was conducted during the SARS-CoV-2 pandemic in Poland, it stands to reason that the pandemic affected the psychological wellbeing of chronically ill patients. A COVID-19 infection, being quarantined and having had contact with a person who was infected, did not significantly affect the outcome measures; however, further research is needed to explore this topic.

P1716: REGULAR HOSPITAL VISITS IMPROVE THE PROGNOSIS OF MULTIPLE MYELOMA PATIENTS

Background: Multiple myeloma（MM）is a common hematological cancer. The overall survival rate of individuals with MM has risen significantly in the previous decade, primarily as a result of the advent and advancements of innovative treatments. As a consequence, given the possibility that cancer will progress to the stage of chronic illness, the post management and regular hospital visit of MM patients are particularly important. Although it seems that long term chronic disease management by regular hospital visit has increased medical expenditure, from the perspective of whole process treatment, it is the best way to achieve standardized treatment and monitoring and may improve the prognosis of MM patients The regular hospital visits means regular hematologist visits with regular treatment and monitor. Irregular hospital visits means visits to other hospital divisions or with no hospital visits. Aims: The aims of this study were to investigate the relationship between regular hospital visits and prognosis of MM and to suggest methods to avoid poor prognoses in MM. Methods: We performed a multicenter retrospective analysis of data from 832 MM patients across 9 centers in China from 2006 to 2020. Sociodemographic (including whether regular hospital visits) and clinical factors at diagnosis and treatment regimens were recorded, and univariate and multivariate analyses were performed. Results: Overall, 30.3% of patients had irregular hospital visits. Patients with irregular hospital visits levels differed from those with regular hospital visits in that they were more likely to be older, and a higher proportion lived in rural areas, were unemployed, and with lower education levels, had lower annual incomes and lacked insurance. Additionally, compared to patients with regular hospital visits, patients with irregular hospital visits had a higher proportion of international staging system (ISS) stage III classification, time to diagnosis is longer and underwent transplantation less often. Patients with regular hospital visits had a median progression-free survival (PFS) of 52.04months, which was better than that of patients with irregular hospital visits (20.3 months, p < 0.001). Similarly, patients with egular hospital visits had a median overall survival (OS) of 107.4months, which was also better than that of patients with irregular hospital visits (37.1 months, p < 0.001). In the multivariable analysis, patients with regular hospital visits had lower relapse rates and higher survival rates than did those with irregular hospital visits in terms of PFS and OS (hazard ratio (HR) = 1.95, p < 0.001; HR =2.80, p < 0.001, respectively). Summary/Conclusion: Irregular hospital visits may independently predict poor survival in MM patients in China.

Phenotypic Profiling of Selected Bacterial Microbes Isolated from Wounds of Diabetic Patients at Jaramogi Oginga Odinga Teaching &amp; Referral Hospital, Kenya

Aims: To phenotypically profile selected bacteria microbes, determine antimicrobial resistance patterns and genetic diversity of resistant genes encoding extended spectrum β-lactamases in bacteria isolated from wounds of diabetes mellitus patients at Jaramogi Oginga Odinga Teaching and Referral Hospital (JOOTRH), Kenya.&#x0D; Study Design: A hospital based cross sectional study design.&#x0D; Place and Duration of Study: Jaramogi Oginga Odinga Teaching and Referral Hospital, Kenya between September, 2019 and February, 2020.&#x0D; Methodology: Pus swabs were collected for isolation of bacteria using conventional techniques and serology involving 117 patients. Samples collected were inoculated onto MacConkey agar, pseudomonas agar media (cetrimide) and blood agar plates then incubated aerobically at 37∘C for 18hours to 24hours. Inoculated plates were examined for growth after 24-48 hours. After attaining pure colonies, Gram staining, colony morphology, and biochemical testing were done. Biochemical tests involving Catalase, Coagulase, Indole, Oxidase, Urease, Citrate utilization tests were done to identify specific bacterial species according to microbiological standard procedures.&#x0D; Results: The results of analysis showed that the prevalence of Gram positive cocci isolated from diabetic wounds was 34.2% while the prevalence for Gram negative rods was 65.8%. The biochemically profiled bacterial microbes were S. aureus, E. coli, P. aeruginosa, K. pneumoniae and Proteus species. S. aureus was the most commonly isolated bacteria with a prevalence of 34.2%. P. aeruginosa had a prevalence of 24(20.5%), K. pneumoniae 22(18.8%), Proteus species 18(15.4 %) and E. coli 13(11.1%). More importantly, the prevalence basing on chi-square results was significantly associated with education level, age, smoking habit, patient setting, drug uptake and hospital visit at 5% level of significance (). &#x0D; Conclusion: Diabetic patients with wounds at JOOTRH, Kenya are more exposed to Gram negative rods infection. The most prevalent Gram negative rod was P. aeruginosa with Its prevalence associated with the patient’s education level, smoking habit, patient setting, irregular hospital visit and adherence to taking of prescribe antibiotics regularly. Therefore, JOOTRH, Kenya healthcare providers are urged to initiate wound infection preventive measures that may include awareness campaigns on the importance of wound management, regular hospital visits, stopping smoking and regular uptake of prescribed drugs.

Adherence to regular surveillance visits for hepatocellular carcinoma in patients with chronic hepatitis C virus infection who achieved sustained virologic response.

Patients with chronic hepatitis C virus (HCV) infection who achieve sustained virologic response (SVR) to anti-HCV therapy, that is the eradication of HCV, are recommended to continue regular hospital visits for the surveillance of hepatocellular carcinoma (HCC) that can develop after SVR. However, it is unclear how well patients with SVR adhere to post-SVR follow-up over the long term. We investigated this adherence and the factors associated with it. Medical record data on regular hospital visits were reviewed in 1329 patients with no history of HCC who achieved SVR by anti-HCV therapy. At the time of SVR confirmation, all patients were advised to continue regular visits, and the risk of post-SVR HCC was explained. The adherence rate of post-SVR follow-up and associated factors were analyzed. Adherence rates decreased continuously over time, as follows: 76.6% at 5 years, 62.4% at 10 years, 48.8% at 15 years, and 35.3% at 20 years after SVR. Adherence rates did not differ based on the degree of baseline liver fibrosis and were significantly lower in patients who achieved SVR by interferon (IFN)-free therapy and those with HCV genotype 2b. Adherence to post-SVR follow-up decreased over the long term, and rates differed by patient background. Adherence was especially poor in patients who achieved SVR by IFN-free therapy, and therefore, strategies are necessary to encourage these patients to maintain their regular schedule of hospital visits.

Pulmonary arterial hypertension associated with congenital heart disease: lessons learnt from the large Turkish Nationwide Registry (THALES).

Pulmonary hypertension is a group of diseases, including pulmonary arterial hypertension associated with congenital heart disease (APAH-CHD), characterized by progressive deterioration in pulmonary hemodynamics associated with substantial morbidity and mortality risk. THALES is a national multicenter, prospective observational registry, providing data on patients with APAH-CHD. The study comprised APAH-CHD patients (>3 months of age) with confirmed diagnosis of right heart catheterization or echocardiographic findings. Initial and follow-up data were collected via regular hospital visits. Descriptive statistics are used for definitive purposes. Overall, 1034 patients aged 3 months–79 years (median 11.2 [Q1–Q3: 2.2–24.3] years) with APAH-CHD were enrolled at 61 centers, 50.3% being retrospectively enrolled. Most had either Eisenmenger's syndrome (49.2%) or systemic-to-pulmonary shunts (42.7%). Patients were mostly in functional class I–II at the time of diagnosis (46.6%). Mean 6-min walk distance (6MWD) was 369 ± 120 m. Mean pulmonary arterial pressure was 54.7 ± 22.2 mmHg for the whole group, and was highest in patients with Eisenmenger's syndrome. Targeted therapies were noted in 398 (38.5%) patients (monotherapy in 80.4%). Follow-up data were available in 506 patients. Survival at 140 months was 79% and was associated with baseline 6MWD >440 m (p = 0.009), brain natriuretic peptide level < 300 ng/L (p < 0.001). Follow-up 6MWD >165 m (p < 0.0001), brain natriuretic peptide level <300 ng/L (p = 0.031), and targeted therapies (p = 0.004) were also predictive of survival. THALES is the largest registry dedicated to APAH-CHD to date and provides important contributions on demographics, clinical characteristics, and gaps in disease management.

A cross-sectional study of socioeconomic status and treatment interruption among Japanese workers during the COVID-19 pandemic.

ObjectivesThe COVID‐19 pandemic has caused interruptions to chronic disease and non‐emergency treatment. The purpose of this study is to examine which socioeconomic status groups are most at risk of treatment interruption among Japanese workers.MethodsThis cross‐sectional internet monitor study was conducted among Japanese workers on December 22‐26, 2020. Out of a total of 33 302 participants in the survey, 9510 (5392 males and 4118 females) who responded that they required regular treatment or hospital visits were included in the analysis. A multilevel logistic model nested in the prefecture of residence was used to estimate the odds ratio (OR) for treatment disruption. We examined separate multivariate models for socioeconomic factors, health factors, and lifestyle factors.ResultsDuring a period of rapid COVID‐19 infection, about 11% of Japanese workers who required regular treatment experienced interruptions to their treatment. The OR of treatment interruption associated with not being married compared with being married was 1.44 (95%CI: 1.17‐1.76); manual labor work compared with desk work was 1.30 (95%CI: 1.11‐1.52); loss of employment when the COVID‐19 pandemic started and continued unemployment compared with being employed over the entire pandemic period was 1.62 (95%CI: 1.13‐2.31) and 2.57 (95%CI: 1.63‐4.07), respectively; and feeling financially unstable was 2.92 (95%CI: 2.25‐3.80).ConclusionTreatment interruption is a new health inequality brought about by COVID‐19 with possible medium‐ and long‐term effects, including excess mortality, morbidity, and productivity loss due to increased presenteeism. Efforts are needed to reduce treatment interruptions among workers who require regular treatment.

Designing A Cloud-Based Framework using Data Mining for Healthcare Services in Remote Areas

Advancement is recently made inthe medicinal field producesnew innovative technologies to the healthcare sector and medical services. Access to quality healthcare is a major problem in remote areas, with a doctor-to-patient ratio as high as 1:20,000 which is far above the recommended ratio of the World Health Organization (WHO). This has been antagonized by a lack of access to critical infrastructures such as the health care facilities, roads, electricity, and many others. To watch basic medical parameters for identifying the abnormalities within the first stage of chronic diseases need regular interval hospital visits, which can be a comparatively costly and time-consuming process. Rare availabilities of doctors or medical centers, ignorance of the people, and proper care at the right time are the prime causes of great medical concern, which leads to unexpected death. This work is an attempt to solve basic health problems and take advice from registered medical experts for the betterment of the targeted community.Rapid development in the cloud environment, health care services are reasonable to the people in remote areas. It is necessary to predict the disease and connect with the doctor to get an early diagnosis of disease. The imperative goal of the paper is to develop a cloud-based framework using data mining to enhance healthcare in remote areas. The cloud-based framework is designed and simulated by using Matlab R2018b. Fast Search-Growing Self Classifier (FS-GS) data mining classifier is developed to separate the data from the cluster to correlate the symptoms of patients with specialists. The classifier parameters like accuracy, precision, recall, sensitivity, and specificity are analyzed to compare the efficiency of the proposed algorithm with the other data mining algorithms like Naive Bayes, Random Forest, K Nearest Neighbor, and Support Vector Machine Linear. The proposed FS-GS data mining Classifier obtains an accuracy of 92%, the precision of 90.01%, recall of 90.06%, the sensitivity of 94.91%, and specificity of 92.6%. For the effectiveness, the proposed algorithm is compared with the various mining data classification algorithms to showmance of the proposed algorithm. Ultimately, the result shows the proposed algorithm scores higher outputs than all other algorithms in real-time scenarios respectively.

Home monitoring for patients with ILD and the COVID-19 pandemic

Home monitoring for patients with ILD and the COVID-19 pandemic

1762P Delivery of systemic anti-cancer therapy during the COVID-19 pandemic

The delivery of systemic anticancer therapy during the COVID-19 pandemic is extremely challenging. Increased hospital visits and active anticancer therapy have been described as risk factors for developing more severe infection. In order to balance the benefits of continuing anticancer therapy with these risks, we undertook a series of system changes in the delivery of cancer care. We examined the rate of COVID-19 infection in patients attending for systemic anticancer treatments and the impact of COVID-19 on therapy delivered at our oncology dayward. Patients who attended our dayward over a 4 month period were included. Data were obtained from electronic patient records and chemotherapy prescribing records. Patients were screened for symptoms of COVID-19 infection at two separate timepoints: the day prior to their visit via telephone, and using a symptom questionnaire given in a preassessment area on arrival at the hospital. This area was established so that patients didn't have to transit through the main hospital. If patients displayed COVID-19 symptoms, they were isolated and a viral swab was arranged. A total of 456 patients attended from January 1st to April 30th. During this time there were 2369 patient visits to the oncology dayward and 1953 intravenous therapies administered. 416 (18%) visits did not lead to treatments, 114 (27%) of which were scheduled non-treatment visits. 194 (47%) treatments were held due to disease-related illness and 108 (26%) treatments were held due to treatment-related complications. 19 patients were identified as having COVID-19 symptoms via telephone screening. 34 patients were symptomatic on arrival at our pre-assessment area and referred for swabs, of which 4 were positive. Those with a negative swab were rescheduled for chemotherapy the following week. Overall, 53 treatments were held due to the screening process. With the introduction of a new patient screening pathway, there have been few treatment disruptions due to the COVID-19 pandemic. The overall rate of symptomatic COVID-19 infection appears low in those who continue on active treatments with regular hospital visits. With careful systematic changes, it is feasible to continue to safely deliver systemic anticancer therapy during the COVID-19 pandemic.

Assessment of tacrolimus and creatinine concentration collected using Mitra microsampling devices.

Current practice requires regular venous blood samples for monitoring of tacrolimus concentrations post renal transplant requiring regular hospital visits. Mitra devices use volumetric absorptive microsampling technology and absorb a fixed amount of blood (10 μL) from a capillary blood sample. They are a viable volumetric alternative to dried blood spots and are able to be posted to the laboratory for analysis. The aim was to develop and validate liquid chromatography-tandem mass spectrometry (LC-MS/MS) assays for tacrolimus and creatinine analysis using Mitra devices. The usefulness of this approach was assessed in renal transplant patients routinely monitored for tacrolimus and creatinine. Routine tacrolimus samples were used to assess the utility and reliability of Mitra sampling. Shared sample preparation for both tacrolimus and creatinine was carried out in a 96-deep well plate; mass spectrometric analysis was then undertaken for tacrolimus followed by re-injection for creatinine analysis. Comparison of 131 Mitra samples with a routine LC-MS/MS assay for tacrolimus showed a minimal bias -5.6% (95% CI -8.5 to -2.7%). Comparison of 135 serum and Mitra samples for creatinine using a fully validated LC-MS/MS assay showed a bias -6.5% (95% CI -8.5 to -4.5%). We have developed assays for tacrolimus and creatinine on fingerprick blood using the Mitra device and believe this approach provides a viable alternative to repeated venepuncture for therapeutic drug monitoring. This method could open up the opportunity for patients to perform tacrolimus and kidney function monitoring at home.

Study of the Effects of Recognition of Stress on Symptoms and Regular Hospital Visits: An Analysis from Japanese National Statistics.

Stress is a risk factor for numerous lifestyle diseases, including dental diseases. The purpose of the present study was to investigate how sensitivity to psychological stress relates to subjective symptoms and regular hospital visits using information from the large-scale database of national statistics. Anonymized data from 10,584 respondents aged 30–79 of the Japanese 2013 Comprehensive Survey of Living Conditions were analyzed. Respondents were classified by age into a middle-aged group and an elderly group, and a contingency table analysis, rank correlation analysis, and binomial logistic regression analysis were performed. Contingency table analysis confirmed that eight items were related to the presence of a recognition of stress, including the presence of subjective symptoms (p < 0.001), the presence of regular hospital visits (p < 0.001), symptoms of periodontal disease (p < 0.001), and self-rated health (p < 0.001). Responses for symptoms and diseases requiring regular hospital visits were ranked in order for a stress group and a no stress group, and it was found that other than fatigue symptoms being ranked highly in the stress group, there were no particular differences. Logistic regression analysis results showed significant odds ratios for six items including: self-rated health (3.91, 95% CI, 3.23 to 4.73), lifestyle awareness (1.96, 95% CI, 1.68 to 2.28), and symptoms of periodontal disease (1.71, 95% CI 1.19 to 2.48). The present study showed that susceptibility to psychological stress is related to awareness of subjective symptoms and to regular hospital visits due to disease, suggesting that these have direct and indirect mutual effects.