Registration Of Complications Research Articles

Primary data from the local registry of periprosthetic hip infection at the National Ilizarov Medical Research Centre for Traumatology and Orthopaedics

Background. Obtaining accurate data on the epidemiology of periprosthetic joint infection (PJI) of the hip in the Russian Federation is a challenging task, which is associated with the peculiarities of statistical registration of complications and the lack of approved routing schemes. The aim of the study — to provide the results of primary analysis of the data from the local registry of hip periprosthetic infection, which reflects all the treatment cases from 01.01.2020 to 31.12.2020. Methods. Since 2021, the Center has been working on retrospective input of the data on patients PJI of the hip treated at the clinic into the electronic version of the registry. The information was collected by studying archived medical records and a medical information system, by examining patients in the outpatient clinic, and by interviewing patients via mobile phone and e-mail. During the period, we treated 449 patients with hip periprosthetic infection. The mean patients’ age was 55.6±12.6 years (Ме — 57; 95% CI: 54.4-56.8). Male patients accounted for 61.6% (n = 277). Results. We were able to evaluate the treatment results in 84% (n = 377) of patients. The mean follow-up period was 5.92±2.55 years (Me — 6; 95% CI: 2.39-2.73). In more than 90% (n = 407) of cases, the infection was classified as chronic (more than 3 weeks of manifestation). At the admission 76,8% (n = 345) of patients had a fistula communicating with the joint cavity. The percentage of lethal outcomes due to sepsis was 1,7% (8/449); recurrences of hip PJI was observed in 6.2% (28/ 449) of cases. Resolution of infection has been achieved in 67% (300/449) of cases. Conclusions. The primary analysis of the data from the local registry of hip periprosthetic infection of the national Ilizarov Center of Traumatology and Orthopedics showed that the average age of patients with hip PJI in our country is significantly lower than in the known national registries. At the same time, the infectious agents were similar: Gram-positive microorganisms accounted for more than 55%. The analysis of the registry data shows a significant decrease in the PJI recurrence rate over the last 5 years.

Long-term consequences of COVID-19 in hospitalized patients over 75 years old

BACKGROUND: The COVID-19 pandemic remains an urgent medical and socio-economic problem. The symptoms, signs and complications of COVID-19 in the acute phase of the disease are now well known, while the long-term consequences of the disease continue to be studied. AIM: The aim of this study was to study the frequency, clinical manifestations of “prolonged” COVID-19 and post-covid syndrome in advanced and old ages people treated in a hospital. MATERIALS AND METHODS: The study included patients aged over 75 years old diagnosed with COVID-19 who were treated in two multidisciplinary hospitals in Moscow in 2021–2022: 94 patients aged 75 to 94 years, including 75.5% of women. At the stage of inpatient treatment, patients were interviewed and medical records were analyzed with registration of demographic data, comorbidities, clinical symptoms and signs of the disease, laboratory markers, complications, and treatment outcome. After 1 and 12 months. after discharge, among the survivors, they were interviewed by telephone interview using a special questionnaire with registration of complaints, repeated hospitalizations and complications of COVID-19, assessment of their psycho-emotional state and identification of cognitive-behavioral disorders. RESULTS: In 70.2% of cases, the disease proceeded in a severe and extremely severe form. The majority of patients before COVID-19 had chronic diseases, most often arterial hypertension (85.9%), chronic heart failure (45.7%) and diabetes mellitus (27.2%). Hospital mortality was 22.6%. Poll after 1 month performed in 41/70 surviving patients (58.6%). Among the symptoms, the most common were fainting (41.5%), palpitations (36.6%), constipation (34.1%), the appearance or increase of shortness of breath (31.7%). Almost every day, 14.6%, 12.2% and 14.6% of the respondents experienced stress, anxiety and apathy. Difficulties in performing hygiene procedures, self-care, dressing were observed in 19.5, 12.2 and 12.2% of cases, respectively; 36.6% experienced severe problems when walking long distances. Poll after 12 months performed in 34/70 people (51.4%). Among the symptoms, the most frequently recorded were behavioral changes (32.4%), increased blood pressure (26.5%), problems with vision (26.5%) and hearing (23.5%). Psycho-emotional disorders were detected less frequently: 2 patients (5.9%) experienced daily stress, 1 respondent (2.9%) was worried about strong agitation and apathy. Difficulties in dressing, performing hygiene procedures, self-care were experienced by 32.4, 29.4 and 8.8% of patients; 20.6% experienced severe problems when walking long distances. CONCLUSIONS: The conducted study indicates a high prevalence of symptoms of “prolonged” COVID-19 and post-covid syndrome in elderly people and the duration of their persistence, which may limit their functional activity and negatively affect the quality of life.

Very Early Loading of a Bone-Anchored Hearing System Is Safe.

To investigate the feasibility of early sound processor loading with two separate bone-anchored hearing aid implants 1 to 2 weeks after implantation. Secondary endpoints included registration of any postoperative complications, skin reactions, and any adverse events. Prospective, nonrandomized, noncontrolled, multicenter clinical trial. Tertiary referral center. Sixty adult patients, eligible for bone-anchored hearing aid surgery, were enrolled. Implantation of the bone-anchored hearing aid implants were done using minimally invasive surgery with tissue preservation. Implant stability quotient (ISQ) values were recorded using resonance frequency analysis. Follow-ups were scheduled 5 to 12 days, 4 to 8 weeks, 6 months, and 12 months postoperatively. Differences between the lowest ISQ values (ISQ low) over time were analyzed by paired-samples t test with a significance level of 0.05. Skin and soft tissue reactions were assessed according to Holger's classification. Loading time of the Ponto Wide implant was 11.6 ± 1.4 days (SD) in average (median, 12 d; range, 7-19 d). Loading of the Ponto BHX implant was done 9.7 ± 3.5 days (SD) postoperatively (median, 9 d; range, 5-19 d). The implant stability increased significantly during the 12-month study period with both implants. One Ponto BHX implant was lost. Skin and soft tissue reactions were few in both groups. Across all planned follow-up visits, no skin and soft tissue reactions were observed in 86% (Ponto BHX implant) and 85% (Ponto Wide implant). Very early loading of sound processors after percutaneous bone-anchored hearing system surgery is safe already 1 to 2 weeks postoperatively.

Formalizing the Informal Sector: Issues, Challenges, and Opportunities

The current research seeks the intention of the informal sector regarding transitioning towards formal sector. The main purpose of this study is to investigate the impact of tax avoidance, high tax rates, complicated registration process, tangible incentive on the ‘willingness to switch’ to formalization of informal sector. This research is conducted at three main commercial areas Raja Bazar, Saddar, and Tench Bhatta of Rawalpindi city, Pakistan. Simple Random Sampling is used with the sample size of 230. Primary data was collected through a structured questionnaire with both close and open ended questions. Linear probability model is used for the analysis. The results show that fifty six percent of the respondents are willing to register their enterprises, however they require some tangible benefits for registering their business. Furthermore, seventy eight percent are of the view that people do not register because they want to avoid taxes. Fifty six percent opine that one of the potential reasons is high tax rates. Seventy four percent considers complications in the registration process restricting people to register their business, and ninety percent firm owners report that getting registered will not prove to be handsome bid for them. Therefore, it is proposed that taxation authorities need to step up its dissemination efforts in reaching out to the informal sector about the potential benefits of registering with the tax authorities. It is also recommended that formalization of businesses should be branded and incentivized.

Publication barriers and facilitators of Cochrane authors in sub‐Saharan Africa: A mixed‐methods study

AbstractBackgroundWell‐conducted systematic reviews contribute to informing clinical practice and public health guidelines. Between 2008 and 2018 Cochrane authors in sub‐Saharan Africa were publishing progressively fewer Cochrane Reviews, compared to non‐Cochrane reviews. The objective of this study was to determine what motivated trained Cochrane authors in sub‐Saharan Africa to conduct and publish non‐Cochrane reviews over Cochrane Reviews.MethodsWe conducted a mixed‐methods exploratory sequential study. We purposely selected 12 authors, who had published at least one Cochrane‐ and one non‐Cochrane review, for in‐depth, semi‐structured interviews. We manually coded and analysed the qualitative data using Grounded Theory approach and used the results to inform the survey questions. Subsequently we surveyed 60 authors with similar publishing experience. We analysed the quantitative data using descriptive and inferential statistics.ResultsFacilitators to publish with Cochrane were a high‐impact factor, rigorous research, and visibility. From barriers, the main categories were protracted time to complete Cochrane Reviews, complex title registration process, and inconsistencies between Cochrane Review groups regarding editorial practices. From the survey, authors confirmed rigorous research and reviewing process (84%), high impact factor (77%), and good mentorship (73%). The major barriers included Cochrane's long reviewing process (70%) and Cochrane's complicated title registration (50%). Authors with publishing experience in the previous 10 years at <95 percentile of systematic review publications, there was no significant difference between the medians for publishing with Cochrane (1) and non‐Cochrane (0) reviews, p = 0.06. Similarly, for those with publishing experience of ≥95 percentile of systematic review publication there was no significant difference between the medians for publishing with Cochrane (4) and non‐Cochrane (6), p = 0.344.ConclusionAuthors considered the visibility and relevance of Cochrane research as a trade‐off point. They continued publishing with Cochrane despite the barriers that they encountered. However, the concerns raised by many authors are worth addressing.

Theoretical basis of the development of business activities in the trade sphere of Ukraine

Complex external conditions of functioning cause increased attention to the study of theoretical foundations and practical prospects for the development of business activities of enterprises in the field of trade in Ukraine. The development of entrepreneurial activity in the field of trade should be based on a thorough understanding of the theoretical basis of the implementation of entrepreneurial activity in the field of trade and its features in Ukraine. Entrepreneurial activity is a guarantee of the further development of the country's economy, the creation of jobs and the general improvement of the population's standard of living. The article defines the main legal bases of business management. The essence, principles, subjects, objects and functions of entrepreneurial activity in Ukraine are considered. The classification of types of entrepreneurial activity in Ukraine is presented, which takes into account possible types of entrepreneurial activity and provides their characteristics for the needs of modern entrepreneurs. Traced approaches to distinguishing retail and wholesale trade. The main characteristics and functions of retail and wholesale trade are defined. Problems in the regulation of entrepreneurial activity in the sphere of trade in Ukraine are highlighted, the main ones being: insufficient support from local authorities; unfavorable conditions of bank lending, high interest on loans, complicated registration procedure; complex procedure for issuing and obtaining permits and licenses; complex reporting procedure; the presence of administrative barriers; the presence of large enterprises that create prerequisites for the development of monopolies. Prospective directions of business regulation in the sphere of trade in Ukraine are summarized. The main problems faced by trade enterprises during military operations on the territory of Ukraine have been determined, the main ones being: the reduction of the domestic market and the deterioration of consumer demand; increased risks to logistics chains and supply; reduced investment and increased economic uncertainty. The prospects for the development of the theory of entrepreneurial activity in Ukraine are summarized.

The Importance of Authentic Deeds in Contracts Keeping Company Secrets

This study aims to review; 1) What aspects need attention in making agreements to keep company secrets?; 2) What is the significance of an authentic Deed in making an agreement keeping company secrets?. The research method used is evaluative descriptive research. Evaluative research is basically centered on final recommendations that affirm that an object of evaluation can be maintained, improved, improved or even dismissed in line with the data obtained. The results showed that; 1 The most that companies do to keep company secrets is done by making written agreements between the company and employees within the company and outside parties with an interest in the company. 2) The tendency to choose the Company's form of protection is at least based on two reasons, including the following: First, because often the substance that is desired to get protection is something that cannot be patented, such as the company's customer list, financial data, business notes and others. Secondly, it is also possible that what wants to be protected is actually possible to be granted a patent, but inventors prefer this form of trade secret protection for various reasons such as unlimited protection periods, more guaranteed confidentiality values, high fees at patent offices and complicated registration formalities

Complications during elective cataract surgery: did the COVID-19 lockdown affect outcomes of ophthalmic surgery?

PurposeOne of the many consequences of the COVID-19 pandemic was a worldwide lockdown of ophthalmic surgery procedures for several months in 2020. The present study aims to answer the following question: does an intermission of cataract surgery for two months cause an increase in complication rates?MethodsIn this retrospective clinical chart review, data was taken from Dutch cataract complication registration database that contains pre-, intra- and postoperative information of patients that underwent cataract surgery in the Netherlands. The amount as well as type of complications were extracted before and after the eight weeks surgical intermission period (SIP): six weeks before (SIP-6) and six weeks after this period (SIP+6) for the years 2016–2020.ResultsA significant decrease in complication rates was found between SIP-6 and SIP+6 in 2020. When SIP+6 2020 is compared to SIP+6 2019, a significant reduction is found. Overall, a downward trend in complication rates was observed in the period 2016–2020.ConclusionA two-months intermission of performing elective cataract surgery does not cause an increase in complications. In contrast, we observe a reduction of postoperative complications. This implicates that refraining from cataract surgery for two months might not compromise operative skills. The possible downward trend over the years can be partially explained by improved training, education and equipment, as well as an increased use of intracameral antibiotics during operation. Possible explanations for the reduction of complications after lockdown could be decreased time pressure as a consequence of a reduced number of operations at the restart of surgeries, and heightened awareness and cautiousness when resuming the operations.

Registration and analysis of complications in the neurosurgical clinic

Registration and analysis of complications in the neurosurgical clinic

Perceptions of and Attitudes toward COVID-19 Vaccination among Urban Slum Dwellers in Dhaka, Bangladesh

Vaccine hesitancy or low uptake was identified as a major threat to global health by the World Health Organization (WHO) in 2019. Vaccine hesitancy is context-specific and varies across time, place, and socioeconomic groups. In this study, we aimed to understand the perceptions of and attitudes toward COVID-19 vaccination through time among urban slum dwellers in Dhaka, Bangladesh. In-depth telephone interviews were conducted between October 2020 and January 2021 with 36 adults (25 females and 11 males) living in three urban slums of Dhaka City, Bangladesh. Follow-up interviews were undertaken in April and August 2021 to capture any shift in the participants’ perceptions. Our findings show that for many there was an initial fear and confusion regarding the COVID-19 vaccine among people living in urban informal settlements; this confusion was soon reduced by the awareness efforts of government and non-government organizations. Women and young people were more interested in being vaccinated as they had had more exposure to the awareness sessions conducted by non-governmental organizations (NGOs) and on social media. However, people living in the slums still faced systemic barriers, such as complicated online vaccine registration and long queues, which led to low uptake of the vaccine despite their increased willingness to be vaccinated. This study highlights the importance of using sources such as NGO workers and television news to debunk myths, disseminate COVID-19 vaccine information, and support adherence to vaccination among urban slum dwellers. Our study underscores the importance of addressing systemic barriers blocking access and understanding community perceptions in order to develop effective communication strategies for vulnerable groups that will then improve the COVID-19 vaccine uptake.

Protecting the Community: Improving Knowledge, Attitude, and Behaviour towards Health Insurance

Indonesia has implemented the National Health Insurance (Jaminan Kesehatan Nasional/JKN) program administered by the BPJS Kesehatan (Health Care and Social Security Agency) to improve the quality of community health and well-being. In eight years, JKN implementation has had many challenges; complicated registration, premium, unsatisfactory service, and the lack of community participation. Policies regarding JKN should be known and understood. This study aimed to know the knowledge, attitudes, and behaviour towards health insurance that will be useful for stakeholders to develop public policies. This study was conducted in Umbulsari B sub-village in Sumberharjo, Prambanan, Yogyakarta, the lowest area of JKN participation based on Sleman HDSS data. We used a cross-sectional design study among 91 respondents who filled out a paper sheet questionnaire that consisted of five sections; demographic characteristics and insurance participation, knowledge, attitudes, actions, and satisfaction with the JKN program. Then, the community service activities; coordination with local stakeholders; JKN participation identification using CHIKA; educational media production and publication. Local stakeholders said that awareness about JKN is low. CHIKA data identification from 529 ID shows that 78.1% had become JKN participants, and 73.3% were "active". The respondents answered most of each knowledge point correctly (score >90%). But there are several things that respondents disagree with: "every participant will get the same health services (19.78%) in attitude point, and health workers in health facilities do not discriminate (21.21%) in satisfaction point. Then 21.21% of respondents rarely use health services routinely for medical check-ups. We developed educational media about the importance of JKN, as well as using CHIKA and Pandawa tutorials. Education about health insurance needs to be carried out continuously according to the local cultural context and innovations so that the community remains protected from the financial burden of accessing health services.

Using electronic registries to study the COVID-19 pandemic and its consequences

The article analyses systems of electronic information resources (registers and databases) in the field of the healthcare in different countries. Not only do such systems provide information to support the treatment of patients, but they also accumulate large amounts of statistics, thus enabling their qualitative operational analysis. Electronic health systems are particularly popular in the United States, and as regards Europe, in Denmark and Norway. These countries created good conditions for the efficient introduction of new electronic information resources that would store all the accumulated information about the COVID 19 pandemic. The aim of the article is to summarise information on the use of electronic registers and databases to create an information base for the study of the COVID-19 pandemic and its consequences in different countries, and to formulate proposals for the improvement of electronic health systems in Ukraine. On the basis of the results of their research, the authors propose a list of electronic registers that can significantly improve the analysis of both the course and the consequences of the coronavirus disease. The list includes: the register of immunisations, a specialised register of complications after the recovery from COVID-19, a register of tests for the presence of this disease or the recovery, etc., as well as a register of hospitalisation cases.

Perancangan Sistem Informasi Pendaftaran Kerja Praktik di PTTelkom Akses Medan Berbasis Mobile


 Samsudin1), 
 1Sistem Informasi, Sains dan teknologi, Universitas Islam Negeri Sumatera utara email: samsudin@uinsu.ac.id, yulisananda7@gmail.com
 
 ABSTRACT
 Telkom Akses Medan is one of the subsidiaries of PT. Telekomunikasi Indonesia Tbk which is engaged in the business of providing construction services and managing network infrastructure. Although this agency is engaged in information technology and networks. But not all activities involve technology. For example, in the registration of practical work at PT. Telkom Akses Medan does not yet have an information system that can support and assist in the registration process and acceptance of practical work from registrants. So that the registrants register manually, namely by coming directly to PT. Telkom Access Medan and brings an application letter and certain conditions needed to apply for practical work registration. With some of these processes, there are several obstacles such as, having to come directly to the company and practical work registrants having to wait for a reply letter that is uncertain when it will come out. Resulting in a series of practical work registration processes being less effective and efficient. With this complicated practical work registration application process, it encouraged us to design an information system for practical work registration at PT. Telkom Access Medan is mobile-based. As a solution to this problem is described with UML (Unified Modeliling Language). In this design, the method used is the waterfall development metedo.
 Keywords: Information System, UML, Registration, Practical Work

The evolution of registration standards for internationally qualified midwives in Australia

BackgroundRegistration as an internationally qualified midwife in Australia can be challenging, as the individual must meet rigorous education and professional competency assessment standards. AimThe purpose of this discussion is to present an overview of the evolution of registration standards for internationally qualified midwives in Australia from 2000 to 2020 and evaluate their effectiveness in promoting internationally qualified midwives' professional integration. ResultsAustralian registration policies for internationally qualified midwives have undergone significant change over the last 20 years. In 2010, registration policy and governance moved from state or territory to national jurisdiction, then these standards were upgraded in 2014, and finally transitioned to an outcome-based assessment (OBA) program in 2020. Inconsistency and lack of transparency in established registration policies and their implementation were revealed, most notably when bridging programs for internationally qualified midwives from non-English speaking backgrounds were discontinued in Australia in 2015, despite reference in the NMBA policy as an available transition program from 2000 to 2020. The implementation of OBA in 2020, which occurred after a significant delay, complicated registration processes further with inclusion of two levels of assessment (MCQ examination and OSCE) and associated expenses. ConclusionEvidence-based strategies and regulatory adjustments are necessary to effectively register internationally qualified midwives in Australia, particularly those from non-English speaking backgrounds.

ЭВОЛЮЦИЯ И ИСТОЧНИКИ ПРАВОВОГО РЕГУЛИРОВАНИЯ ODR В США

Introduction:the article explores the history of formation and development of online dispute resolution (ODR) in the USA. The author analyzes the basic concepts and characteristics of these technologies and gives examples of their use in the practice of private ODR providers and U.S. courts. The main sources of legal regulation of ODR in the USA are the rulings of state courts based on the ‘ODR Standards’ of international organizations, including UNCITRAL, NCTDR, ICODR, etc., as well as scientific works of American scientists and practitioners. Purpose: to provide an insight into the emergence and development of online dispute resolution (ODR) in the practice of private ODR providers and the practice of U.S. courts by analyzing court reports, international acts, and academic sources. Methods: theoretical methods of formal and dialectical logic; empirical methods of comparison, description, interpretation; special scientific methods such as legal-dogmatic and the method of interpretation of legal norms. Results: the study found that there is currently no legal definition of ODR in the United States; governmental bodies (including courts) and private ODR pro-viders rely on their own vision and understanding of ODR, using non-binding documents from international organiza-tions as well as academic studies developed by U.S. scholars and practitioners. There is also no common doctrinal defi-nition of ODR. Conclusions: 1) The U.S. National Center for State Courts, on its website, defines judicial (court-related) ODR as ‘a public facing digital space in which parties can convene to resolve their dispute or case’. 2) Scholars define judicial ODR as a method of ADR (alternative dispute resolution) aimed at resolving civil disputes using online plat-forms attached to a court rather than face-to-face hearings, mediation, or arbitration. 3) Barriers to the use of ODR in U.S. courts are: a) continuing transition from paper to electronic documents; b) complicated registration on ODR plat-forms; c) lack of ‘intuitive’ options for working with documents on the platform and finalizing the ODR process; d) lack of reference documents. 4) The experience of U.S. state courts in implementing ODR pilot programs as well as non-binding documents of international (UNCITRAL, ICODR) and U.S. ODR standards compliance organizations (NCTDR, ABA) can be used to improve Russian legal acts.

Modified dindo-clavien system for registration of perioperative complications in children undergoing adenotonsillectomy.

Surgical procedures in children are among the most commonly performed procedures in otolaryngology. Perioperative safety and documentation of complications are becoming increasingly important. This study investigates perioperative complications in a clinical cohort of children with adenotonsillar hyperplasia undergoing adenotonsillectomy using the standardized Dindo-Clavien reporting system. Retrospective evaluation of 402 children who underwent adenotonsillectomy between 2009 and 2015. Patient parameters including all perioperative complications were investigated. In the study, 124 complications were found (106 mild, 16 severe). According to the Dindo-Clavien classification, 93 grade I, 15 grade II, 5 grade III, 11 grade IV and 0 grade V complications were documented. Complications were associated with additional diagnoses (p = 0.001), long-term medication intake (p = 0.003), duration of hospitalization (p < 0.001) and duration of surgery (p < 0.001), undergoing tonsillotomy (p = 0.022) or tonsillectomy (p < 0.001), differences in ASA score (p = 0.005) and differences in OSA-18 score (p = 0.011). Severe complications, classified as grade III and IV, were associated with premature birth (p = 0.026), additional diagnoses (p = 0.017), long-term medication intake (p < 0.001) and differences in ASA score (p =< 0.001). The Dindo-Clavien classification is a standardized reporting system which can also be used for surgical procedures in children with adenotonsillar hyperplasia. The system shows associations with clinical parameters and thus can help to identify subgroups at risk of severe complications.

Major complications and mortality after ventral hernia repair: an eleven-year Swedish nationwide cohort study

Background and aimsVentral hernia repair is one of the most common surgical procedures performed worldwide. Despite the large volume, consensus is lacking regarding indications for repair or choice of surgical method used for reconstruction. The aim of this study was to explore the risk for major complications and mortality in ventral hernia repair using data from a nationwide patient register.MethodPatient data of individuals over 18 years of age who had a ventral hernia procedure between 2004 and 2014 were retrieved from the Patient Register kept by the Swedish National Board of Health and Welfare. After exclusion of patients with concomitant bowel surgery, 45 676 primary surgical admissions were included. Procedures were dichotomised into laparoscopic and open surgery, and stratified for primary and incisional hernias.ResultsA total of 45 676 admissions were analysed. The material comprised 36% (16 670) incisional hernias and 64% (29 006) primary hernias. Women had a higher risk for reoperation during index admission after primary hernia repair (OR 1.84 (1.29–2.62)). Forty-three patients died of complications within 30 days of index surgery. Patients aged 80 years and older had a 2.5 times higher risk for a complication leading to reoperation, and a 12-fold higher mortality risk than patients aged 70–79 years.ConclusionAge is the dominant mortality risk factor in ventral hernia repair. Laparoscopic surgery was associated with a lower risk for reoperation during index admission. Reoperation seems to be a valid outcome variable, while registration of complications is generally poor in this type of cohort.

Detailed statistical analysis plan for the neurological complications in endoscopic versus open radial artery harvest (NEO) randomised clinical trial.

Coronary artery bypass grafting can be conducted using the radial artery as a bypass graft. However, it remains unclear which harvesting method is superior, i.e. endoscopic or open radial artery, and which site for proximal anastomosis of the radial artery has the greatest benefits? The NEO Trial is a single site randomised clinical trial with a 2 × 2 factorial design. The first comparison assesses endoscopic versus open radial artery harvest with a primary outcome of hand function and secondary outcomes of neurological deficits through clinical exams and neurophysiological studies. The primary outcome is postoperatively hand function at three months. We anticipate a mean difference of 3 points with a standard deviation of 8 points, a power of 90%, and a type I error of 5%, resulting in a required sample size of 300 participants randomised 1:1. Secondary outcomes are neurological deficits (based on nerve conduction measurements, algometry test and von Frey hair test), clinical neurological examination of cutaneous sensibility, and registration of complications in the donor arm (haematoma formation, wound dehiscence, and/or infection). The second comparison assesses two different proximal anastomotic sites, i.e. aorto-radial anastomosis versus mammario-radial anastomosis. The primary outcome is a composite of cerebrovascular events and the secondary outcome is graft patency evaluation by multi-slice computer tomography-scan. These outcomes will be assessed at 1year postoperatively, and the results of this comparison will be exploratory only. Both comparisons will be analysed using intention-to-treat and intervention groups will be compared using linear regression, logistic regression, or Mann-Whitney U test depending on data type. Two independent statisticians will follow the present plan and conduct the analyses which will hereafter be fused into a final analysis based on consensus. This detailed analysis plan will increase the validity of the NEO trial results by predefining the statistical analysis in detail. ClinicalTrials.gov identifier: NCT01848886 . Registered 25 February 2013. Danish Ethics committee number: H-3-2012-116. Danish Data Protection Agency: 2007-58-0015/jr. n:30-0838.

Factors associated with the registration of infant feeding and clinical complications in the Children’s Handbook

RESUMO Este artigo teve como objetivo analisar os fatores associados ao registro da alimentação infantil e intercorrências clínicas na caderneta de crianças menores de 3 anos, residentes em João Pessoa, Paraíba, Brasil. Trata-se de um estudo transversal, realizado com 424 cadernetas de crianças menores de 3 anos, cadastradas em Unidades de Saúde da Família de João Pessoa, Paraíba. Os dados foram coletados no período de maio a novembro de 2019 e analisados a partir da estatística descritiva e inferencial, com os testes Quiquadrado e Exato de Fisher. Constatou-se que apenas 1,9% das cadernetas analisadas apresentavam dados relacionados com a alimentação e que 0,9% tinha registrado algum dado acerca das intercorrências clínicas da criança. Ademais, as características sociodemográficas dos responsáveis/cuidadores e das crianças não apresentaram associação estatística significativa com os registros da alimentação e das intercorrências clínicas na Caderneta da Criança. Conclui-se que é precário o registro sobre alimentação infantil e intercorrências clínicas na Caderneta da Criança. Esta realidade representa uma lacuna à continuidade do cuidado à criança e poderá prejudicar os esforços para a redução da morbimortalidade infantil.

Self-registration of constant-step rotating Mueller matrix polarimeters.

Time-division framework is commonly used in Mueller matrix polarimeters (MPs), which takes extra numbers of images at the same position in an acquisition sequence. In this Letter, we utilize measurement redundancy to raise a unique loss function which can reflect and evaluate the degree of mis-registration of Mueller matrix (MM) polarimetric images. Further, we demonstrate that the constant-step rotating MPs have a self-registration loss function free from systematic errors. Based on this property, we propose a self-registration framework, which is able to apply efficient sub-pixel registration skipping the calibration procedure of MPs. It is demonstrated that the self-registration framework performs well for tissue MM images. By combining with other powerful vectorized super-resolution methods, the framework proposed in this Letter has the potential to handle more complicated registration problems.