Regions Of Theworld Research Articles

Greenhouse gas emissions patterns and insertion in global value chains: a comparative study between Brazil and China (2000–2016)

PurposeThis study aims to analyze and compare the relationship between international trade in global value chains (GVC) and greenhouse gas (GHG) emissions for Brazil and China from 2000 to 2016.Design/methodology/approachThe input-output method apply to multiregional tables from Eora-26 to decompose the GHG emissions of the Brazilian and Chinese productive structure.FindingsThe data reveals that Chinese production and consumption emissions are associated with power generation and energy-intensive industries, a significant concern among national and international policymakers. For Brazil, the largest territorial emissions captured by the metrics come from services and traditional industry, which reveals room for improving energy efficiency. The analysis sought to emphasize how the productive structure and dynamics of international trade have repercussions on the environmental dimension, to promote arguments that guide the execution of a more sustainable, productive and commercial development strategy and offer inputs to advance discussions on the attribution of climate responsibility.Research limitations/implicationsThe metrics did not capture emissions related to land use and deforestation, which are representative of Brazilian emissions.Originality/valueComparative analysis of emissions embodied in traditional sectoral trade flows and GVC, on backward and forward sides, for developing countries with the main economic regions of the world.

“Neither Water, nor War:” the Problem of Fresh Water in International Relations of the First Quarter of the 21<sup>st</sup> Century

In this article, the author compares the objective dynamics of changes in the state of the water problem since the beginning of the 21st century, which has continued to worsen in most regions of the world, and its foreign policy dimension, noting the transition from the global water alarmism of the 1990s to the challenges for small and medium powers, in solving the problems in which no major actor is yet actively interested. Fresh water, despite the slogans at the end of the last century about future water wars, the “blue oil” and the “new gold” of the 21ST century, has not become, and is unlikely to become, the cause of confrontation between great powers, while medium and small powers are still confine themselves to more traditional forms of conflict, including in the Tigris, the Euphrates and the Jordan basins, which have been seen for decades as a testing ground for future water wars. This does not negate the role of water bodies and ecosystems in promoting development or, conversely, in perpetuating the poverty and backwardness in entire regions. Waters remain in competition as an important source of water-intensive goods that can be converted into valuable assets – water-intensive goods, energy or the ability to achieve higher levels of the Human Development Index. And, of course, they can be used to exacerbate ethnic and political conflicts. This is where the potential of Russia, the world’s second water power, comes into play, both in terms of directly regulating regional water challenges and in influencing the approaches of international organizations and associations, in which Moscow plays a prominent role.

Adopting telemedicine in the fight against antimicrobial resistance in West Africa.

The detrimental effects of antimicrobial resistance (AMR) have called for several approaches in the fight against it in West Africa, where telemedicine is still in its infancy. In West Africa, self-medication is prevalent because the majority of these medications are easily accessible due to insufficient regulatory structures that control their production, distribution, and consumption. Also, access to healthcare facilities and professionals is limited. All of these and other inadequacies consequently result in the emergence of antimicrobial-resistant organisms. AMR, which is now a major global health crisis according to the WHO, may cause the deaths of about 10 million people before 2050, and Africa may make up 41% of these deaths, with the Western part of this continent affected the most. While several approaches have been adopted, unlike in other regions of the world, the use of telemedicine in West Africa to fight AMR has rarely been studied or considered and where it is now in partial use, its efficacy is constrained by several factors. This paper discusses the roles of telemedicine, the limitations to its application in the fight against AMR, and suggests remedies for these limitations.

Urban ozone variability using automated machine learning: inference from different feature importance schemes.

Tropospheric ozone is an air pollutant at the ground level and a greenhouse gas which significantly contributes to the global warming. Strong anthropogenic emissions in and around urban environments enhance surface ozone pollution impacting the human health and vegetation adversely. However, observations are often scarce and the factors driving ozone variability remain uncertain in the developing regions of the world. In this regard, here, we conducted machine learning (ML) simulations of ozone variability and comprehensively examined the governing factors over a major urban environment (Ahmedabad) in western India. Ozone precursors (NO2, NO, CO, C5H8 and CH2O) from the CAMS (Copernicus Atmosphere Monitoring Service) reanalysis and meteorological parameters from the ERA5 (European Centre for Medium-Range Weather Forecast's (ECMWF) fifth-generation reanalysis) were included as features in the ML models. Automated ML (AutoML) fitted the deep learning model optimally and simulated the daily ozone with root mean square error (RMSE) of ~2 ppbv reproducing 84-88% of variability. The model performance achieved here is comparable to widely used ML models (RF-Random Forest and XGBoost-eXtreme Gradient Boosting). Explainability of the models is discussed through different schemes of feature importance, including SAGE (Shapley Additive Global importancE) and permutation importance. The leading features are found to be different from different feature importance schemes. We show that urban ozone could be simulated well (RMSE = 2.5 ppbv and R2 = 0.78) by considering first four leading features, from different schemes, which are consistent with ozone photochemistry. Our study underscores the need to conduct science-informed analysis of feature importance from multiple schemes to infer the roles of input variables in ozone variability. AutoML-based studies, exploiting potentials of long-term observations, can strongly complement the conventional chemistry-transport modelling and can also help in accurate simulation and forecast of urban ozone.

Decreased river runoff on the Mongolian Plateau since around 2000

ContextMongolian Plateau is one of the largest contingent arid and semi-arid regions of the world. Rivers on the plateau provide vital water for millions of indigenous Mongolian people and numerous endangered wildlife, but are increasingly disturbed by climate change and human activities. Yet, long-term changes in river runoff across the plateau remain poorly studied due to data unavailability.ObjectivesThis study aimed to analyze the temporal trends in gauged river runoff on the Mongolian Plateau, identify drivers of the observed changes, and evaluate CMIP6 models' performance in simulating historical runoff changes across the plateau.MethodsWe compiled possibly the largest database of long-term (20 - 71 years) river runoff for the plateau comprising measurements over 30 major rivers. Statistical analyses were conducted to assess trends in river runoff and correlations between runoff and climatic variables. Additionally, we applied the Budyko curve framework to identify the influence of human activities on river runoff in specific basins. Furthermore, we compared ground-measured runoff data with simulations from CMIP6 models to evaluate the ability of CMIP6 models to replicate runoff dynamics in typical arid and semi-arid regions.ResultsWe observed pervasive and abrupt reduction in runoff in 21 out of the 30 rivers within 5 years before or after the year of 2000. Variations in river runoff were most significantly caused by changes in total precipitation (TP). In particular, 27 rivers experienced abrupt TP changes around 2000, and there was a significant positive correlation between annual fluctuations in TP and river runoff for 18 rivers. In addition to climate factors, the influence of human activities was identified in certain basins. The CMIP6 simulations failed to capture the abrupt changes in runoff occurred pervasively across the plateau around 2000.ConclusionsAround 2000, major rivers on the Mongolian Plateau, especially in Inner Mongolia, experienced runoff declines, primarily due to TP changes. Human activities like dam construction and water diversion further influenced local runoff. CMIP6 historical runoff simulations were inaccurate across the plateau, highlighting the difficulty of simulating river runoff in this critical region. Our study could contribute to a more comprehensive understanding of the water resource changes on the Mongolian Plateau, with direct implications for enhancing ecological conservation and management practice.

Benign Lipomatous Soft Tissue Tumors in Nigerians: An Analysis of the Clinical and Morphological Features of a Common but Important Entity.

Introduction Benign lipomatous tumors are soft tissue tumors that exhibit a predominant adipocytic phenotype. Lipomas are the archetype and are the most common benign soft tissue tumors in adults but relatively uncommon in children. Their sex incidence is equivocal. They sometimes occur in combination with other mesenchymal elements, giving rise to variants including fibrolipoma, angiolipoma, myolipoma, spindle cell lipoma, chondroid lipoma, osteolipoma, and chondrolipoma. Their clinical significance is mainly due to the cosmetic disfigurement of patients and the differential diagnosis of malignant soft tissue tumors. Occasionally, due to their large size or presence near vital organs, they may cause life-threatening and/or excruciating pressure symptoms. This study was purposed to address the dearth of local studies on the clinical and morphological characteristics of benign lipomatous tumors in Nigerians, to compare these with those of other populations, and to establish baseline data. Materials and methods This was a retrospective study of all benign lipomatous tumors seen in the anatomic pathology and forensic medicine department of Asokoro District Hospital, Abuja, Federal Capital Territory, Nigeria, over an eight-year period. Surgical pathology reports were retrieved for patients' biodata and clinical information. The appropriate slides were retrieved, and reviewed, and new sections were cut where necessary. The tumors were classified according to the 2020 World Health Organization (WHO) guidelines and categorized based on size as small, medium, or giant. The data obtained were analyzed, and the results were presented as tables, bar charts, ratios, and percentages. Results Four hundred and eighteen cases met the inclusion criteria. Of these, 58.4% (244/418), occurred in females, while 41.6% (174/418) occurred in males. The age range was six to 91 years, while the median age was 42 years. The least number of cases, 0.5% (2/418), were seen in patients aged less than 10 years, while the majority, 35.4% (148/418), occurred in the fifth decade, followed by 27.8% (116/418) in the fourth. Size-wise, the majority of tumors, 60% (253/418), were medium, followed by small, 22.8% (95/418). Giant-sized tumors significantly accounted for 16.7% (70/418) of the cases. The diagnostic spectrum comprised conventional lipoma and variants such as fibrolipoma, spindle cell lipoma, pleomorphic lipoma, angiolipoma, chondrolipoma, intramuscular lipoma, and osteolipoma. Lipoma and fibrolipoma dominated with 87.1% (364/418) and 10.0% (42/418), respectively, while the rest accounted for <3%. The majority, 31.8% (133/418), occurred in the back/shoulder region, followed by the lower limb with 18.2% (76/418). Only two cases occurred in the abdominal/pelvic region. More tumors occurred in females in all the regions except the head and neck, which had a male-to-female ratio of 1.5:1. Multiple site tumors were more common in males in a ratio of 2.5:1. Most, 41.1% (39/95), of the small-sized tumors, occurred in the head/neck region, largely involving the face, 48.7% (19/39). Conclusion Our study showed many similarities in the clinical and morphological features of benign lipomatous tumors between Nigerians and other regions of the world. A notable finding, however, was the significantly higher proportion of giant benign lipomatous tumors when compared tostudies from other regions, a finding that warrants further studies.

Mushroom Picking as a Special Form of Recreation and Tourism in Woodland Areas—A Case Study of Poland

The paper looks at the potential benefits of mushrooms in terms of health, recreation, and tourism. Mycotourism is an innovative, specialised tourism product that has been successfully introduced in some regions of the world, helping to combat seasonality and promote economic development in rural areas. The aim of the study was to analyse the development of mycotourism in Poland in comparison with other countries. As a method, a questionnaire on the cultural significance of mushrooms was developed and disseminated via social media. It was found that there are strong mycophilic tendencies in Poland, leading to a strong interest in mushrooms, both in terms of cultural and culinary traditions. They are also a factor that attracts tourists to the forest areas. In contrast, the UK and Germany are more mycophobic, resulting in a lower interest in mushrooms, limited culinary use, and a lower awareness of their role in the ecosystem and their potential health benefits. The low average score for knowledge of mushrooms in countries such as the UK indicates a need for increased mycological education that can contribute to a better understanding of the conservation of these important components of the forest floor. The high proportion of people who see mushroom picking in Poland as a form of recreation emphasises its role as an important cultural and potential nature tourism asset. In Poland, where long traditions are associated with mushrooms and mushroom picking, they have a strong influence on the choice of mycological tourism, especially in regions with a rich tradition of mushroom picking. The high percentage of mushrooms used for culinary purposes, especially in Poland, emphasises their value and influences the health component of the diet, which is rich in proteins, vitamins, and minerals. Research has shown that mushroom consumption and its effects on health are perceived positively. This is evidenced by higher ratings in Poland than in the UK and Germany, indicating a general awareness of the health benefits of mushrooms, even though their use in medicine remains limited. The low level of awareness of the role of mushrooms and their potential health benefits suggests that educational and promotional activities should be increased to sensitise the public to mushrooms.

Detection of plastic, cellulosic micro-fragments and microfibers in Laternula elliptica from King George Island (Maritime Antarctica)

It is generally acknowledged that microplastic pollutants are prevalent in ocean waters and sediments across a range of tropical, temperate, subpolar, and polar regions. The waters surrounding King George Island are significantly impacted by human activities, particularly those related to scientific stations, fishing, and tourism. Organisms, such as Laternula elliptica, can be used as environmental monitors due to the likelihood that they will bioaccumulate pollutants. The goal of this study was to quantify and identify plastic and cellulosic micro-fragments and microfibers present in the soft body of clams (n = 21), collected from Fildes Bay near sewage and wastewater discharges. Plastic and cellulose microfragments and microfibers were counted, and their compositions were determined using FT-IR. All 21 individuals sampled contained fragments and fibers, with a total of 900 items detected (42.86 ± 25.36 mean ± SD items per individual), or 1.82 items g.wet mass−1. 58 % of items were cellulose and 22 % plastic. Considering the plastic polymer compositions, 28.57 % were polyethylene terephthalate (PET), 21.43 % acrylic, 14.29 % high-density polyethylene (HDPE), 14.29 % Polypropylene (PP), 7.14 % ultra-high drawn polyethylene filament (UHMWPE), 7.14 % polyester and 7.14 % Polyethylene. The quantities and prevalence of MP in L. elliptica were higher than those found in other Antarctic marine species, and even in bivalves from populated regions of the world. Our work assessed the pollution status of L. elliptica near an effluent of wastewater plants and found that 95 % of individuals displayed MP and 100 % microfibers that could impact their population.

Analysis of trends in the functioning of water and air transport in the regions of the Russian Federation against the backdrop of emerging crises

The article discusses current trends in the aviation industry, growth factors in passenger and cargo traffic, key players in various regions of the world, regulatory requirements and market challenges in comparison with one of the most important industries in Russia and the world - water transport. A review of new aircraft concepts has been completed. The authors note the resumption of production of domestic aircraft in the context of the implementation of a policy of active import substitution. The work identifies the advantages of using medium-haul and long-haul aircraft by Russian carriers, and presents the structure of the market positions of the largest airlines in Russia in recent years. The study also assesses the impact of the COVID-19 pandemic on the situation in this area and examines alternative strategies for its recovery. In order to improve flight safety and ensure the sustainability of environmental practices, the need for the development of the domestic aviation industry and its adaptation to the ongoing international transformations is substantiated, which implies the unconditional use of new technologies. The article draws a parallel between air and water transport and compares Russian and foreign indicators of these industries. Thus, a comparison of the dynamics of development of the aviation industry and water transport will reveal their similarities and differences, various advantages and disadvantages, as well as their impact on the global economy.

Chemical composition of the essential oil of Eucalyptus genotypes susceptible or resistant to the gall-forming wasp Leptocybe invasa Fisher &amp; La-Salle, 2004 (Hymenoptera: Eulophidae)

Eucalyptus are trees native to Australia and have been cultivated in various regions of the world. In its worldwide expansion, several native and exotic insects began to use these plants for their survival. Leptocybe invasa Fisher &amp; La-Salle, 2004 (Hymenoptera: Eulophidae) is a gall wasp that lay eggs into leaves, young branches, and petioles causing galls; however, there are resistant and susceptible eucalyptus genotypes to gall formation. This study aimed to compare the chemical composition of eucalyptus genotypes and relate it to resistance and susceptibility to gall formation. Leaf oils were extracted by steam distillation and oil compositions were analyzed. The essential oils of eucalyptus genotypes resistant to gall formation had 12 constituents, which do not occur in susceptible genotypes, probably one of the factors that contributes to the resistance of these plants to gall formation. Thus, we suggest an early evaluation of resistant or susceptible eucalyptus genotypes, based on the chemical composition of the essential oils of these plants, avoiding economic losses of planting susceptible genotypes.

Population parameters and heterogeneity in survival rates of Indo-Pacific humpback dolphins in a heavily urbanized coastal region of southeast China: implications for conservation

The Pearl River Delta (PRD) region on the southeast coast of China is among the largest and most populated metropolitan regions of the world, subjecting the Indo-Pacific humpback dolphins (Sousa chinensis) inhabiting coastal waters of this region – apparently the largest population of this species – to intense anthropogenic pressure. In this 5-year study (2011-2015), we applied mark-recapture techniques to quantify population parameters of humpback dolphins in the main body of the extensive estuarine system of the Pearl River, the Lingding Bay (LB), the most urbanized and industrialized part of PRD. The super-population size was estimated at 928 individuals (95% CI=823-1046), which however over-represents the latest number of extant animals. Annual estimates fluctuated between 708 and 750 dolphins, and likely reflect most accurately the latest/current number of humpback dolphins in waters of LB. Both the overall and annual estimates generated by our study are considerably lower than previously published abundance estimates. Apparent survival rates were generally low, estimated at 0.943 (SE = 0.008, 95% CI = 0.929-0.958) and 0.815 (SE = 0.025, 95% CI = 0.766-0.866) for adults and juveniles, respectively. In conjunction with limited recruitment, they may have led to a substantial decline in population numbers over the past two decades. Notably, dolphins exhibited heterogeneous apparent survival rates across the complex anthropogenic seascape of LB. Adult individuals that use Hong Kong waters as their primary habitat exhibited 6.2% higher survival rates than those in other parts of LB. This difference tripled (19.2%) for juveniles, a likely expression of their susceptibility to environmental and/or anthropogenic stresses. We suggest that the difference in survival is largely due to heterogeneous anthropogenic stressors that vary spatially across the estuary, among which habitat loss, pollution, and declining prey resources appear to be the primary threats. Based on our latest findings, we call for a strategic conservation planning with the highest priority given to preserve the remaining key dolphin habitats in Hong Kong waters, and to quantify and mitigate the impacts of major stressor(s) in Guangdong (mainland China) waters. Given the encroachment of ever-more-intense human activities on the coastal habitats of humpback dolphins, understanding their demographic response and the underlying mechanisms of the population processes may prove instrumental in the formulation of a conservation management strategy that can secure their continuous survival.

The Brazilian diaspora: Intra‐community dynamics and differentiating factors among Brazilian migrants worldwide

AbstractWhile the Brazilian diaspora scholarship is a vibrant literature that emerged in the 1980s and has gained prominence over the years, it remains geographically dispersed. Most studies focus on Brazilian migrants' experiences in a specific country or region of destination, and less attention has been paid to issues that influence the Brazilian diaspora transnationally. While the experiences of Brazilian migrants in different regions are varied and dependent on exogenous factors in the host society, this article reviews and discusses common markers of identity and positioning that shape intra‐community social dynamics between Brazilians who reside in different regions of the world. These ‘endogenous differentiating factors’ often produce tensions and intra‐community stratification, and may be carried from Brazil to the host community or produced in the host society. This article aims to integrate the geographically dispersed literature and emphasise commonalities experienced by Brazilians worldwide. It also argues that the focus on endogenous differentiating factors relates to a scholarly trend to frame the ‘Brazilian community’ as a heterogeneous entity with its own social dynamics rather than a homogenous ethnic group.

Targeting human inosine 5’ monophosphate dehydrogenase type 2 for anti-dengue lead identification – a computational approach

Dengue is a rapidly evolving arboviral disease that mainly affects tropical and subtropical regions of the world. The lack of therapeutic drugs and effective vaccines suggests that further resources need to be investigated. The effectiveness of the existing dengue vaccine is improbable as its efficacy depends on prior exposure to the dengue virus(DENV). Although the mechanism underlying the action of bioactive compounds to limit viral replication is less studied and still needs to be further explored, medicinal plants are excellent alternatives to combat DENV infection. In the current study, an in silico screening of phytochemicals from Annona reticulata Linn. against human Impdh2 was performed using Autodock Vina. Daucosterol (−9.0 kcal/mol) and Kaurenoic acid (−8.5 kcal/mol) were chosen as the top hits based on molecular interaction analysis. The hits were further exposed to pharmacokinetics and toxicity properties to determine their drug-like parameters. Molecular dynamics simulation studies of the Impdh2-top hits were carried out to investigate their kinetic behaviour and structural stabilities. The binding free energies of the Impdh2-hit complexes were determined using MM-PBSA analysis. According to the overall conclusions of the study, Daucosterol showed good binding affinity and high structural stability to the binding site residues of the target, therefore it is recommended as a lead compound against dengue. Communicated by Ramaswamy H. Sarma

A Remote Sensing Approach to Estimating Cropland Sustainability in the Lateritic Red Soil Region of China

Spatiotemporal assessment and a comprehensive understanding of cropland sustainability are prerequisites for ensuring food security and promoting sustainable development. However, a remote sensing-based approach framework that is suitable for large-scale and high-precision assessment and can reflect the overall sustainability of cropland has not yet been developed. This study considered a typical lateritic red soil region of Guangdong Province, China, as an example. Cropland sustainability was examined from three aspects: natural capacity, management level, and food productivity. Ten typical indicators, including soil organic matter, pH, irrigation guarantee capability, multiple cropping index, and food productivity, among others, were constructed using remote sensing technology and selected to represent these three aspects. Based on the indicator system, we assessed the spatiotemporal patterns of cropland sustainability from 2010 to 2020. The results showed that the natural capacity, management level, and food productivity of cropland had improved over the 10 years. The cropland sustainability score increased from 67.95 to 69.08 over this period. The sustainability scores for 68.64% of cropland were increased and were largely distributed in the eastern and western region of the study area. The croplands with declining sustainability scores were mostly distributed in the central region. The prefecture-level regions differed in cropland sustainability, with Zhongshan, Zhuhai, and Qingyuan cities exhibiting the highest values, and Zhanjiang the lowest. Exploring the underlying mechanisms of cropland sustainability and proposing improvement measures can guide decision-making, cropland protection, and efficient utilization, especially in similar lateritic red soil regions of the world.

Global, regional, and national temporal trends of diet-related ischemic stroke mortality and disability from 1990 to 2019.

Stroke is the second leading cause of death and the third leading cause of disability in the general population worldwide. However, the changing trend of ischemic stroke burden attributable to various dietary risk factors has not been fully revealed and may contribute to a better understanding of stroke epidemiology. Our article aimed to evaluate the temporal trend of diet-related ischemic stroke burden to inform future research and policy-making. This analysis was based on the data from the Global Burden of Disease (GBD) Study 2019 (spanning years 1990 to 2019), and we used the joinpoint regression to model temporal trends in diet-related ischemic stroke burden across countries and regions of the world during the study period. Six specific dietary factors known to influence stroke risk, including sodium, red meat, fiber, vegetables, whole grains, and fruits, were evaluated in the GBD study to determine their individual and joint impact on ischemic stroke. The changing trend was primarily measured by the average annual percent change (AAPC). Age-standardized rates (ASRs) of mortality and years lived with disability (YLD) per 100,000 population were used to evaluate disease burden. Finally, the socioeconomic background, which was quantified as sociodemographic index (SDI), and its association with diet-related ischemic stroke burden were also explored with the Pearson correlation coefficient. During the study period, the ischemic stroke ASR of mortality attributable to overall dietary risk decreased by an average of 1.6% per year, while the ASR of YLD decreased by an average of 0.2% per year. High sodium diet was still a key driver of diet-related ischemic stroke, accounting for 8.4% and 11.0% of deaths and disabilities, respectively, in 2019. In addition, we found a negative association between temporal evolution of stroke burden and socioeconomic background (r = -0.6603 for mortality and r = -0.4224 for disability, P < 0.001), which suggested that the developing countries with weak social and economic foundation faced greater challenges from the ongoing burden of diet-related strokes compared with developed countries. Our study found declining trends and revealed the current status of diet-related ischemic stroke mortality and disability. Interdisciplinary countermeasures involving the development of effective food policies, evidence-based guidelines, and public education are needed in the future to combat this global epidemic. The data used for analysis were open-access and can be obtained from https://vizhub.healthdata.org/gbd-results/.

Construction of prokaryotic system for expression of porcine circovirus type 2 ORF-2 gene fragment

Porcine circovirus-associated diseases (PCVDs) are among the most significant challenges for pig farming in developed countries. Porcine circovirus type 2 (PCV-2) is considered the main etiological agent of postweaning multisystemic wasting syndrome in piglets. Mass PCVD occurrence has been reported in most regions of the world, that results in serious economic consequences. Optimal PCVD prevention is known to be achieved through a set of veterinary and sanitary measures in combination with vaccination. High evolutionary virus variability facilitating new genotype and strain emergence requires development of new candidate recombinant vaccines against PCV-2 infection. The study was aimed at construction of prokaryotic system for PCV-2 ORF-2 gene fragment expression and its functionality assessment. A genetic insert constructed from the most immunogenic type-specific PCV-2 epitopes based on genotype 2a, 2b, 2d strain and isolate consensus sequence was cloned into the expression vector pET-22b(+) that was incorporated into the Escherichia coli strain Rosetta 2(DE3). The transformants were selected based on the marker gene of ampicillin resistance on a selective medium. Target gene expression was induced by adding of isopropyl-β-D-1-thiogalactopyranoside at different concentrations. As a result, Escherichia coli Rosetta 2(DE3)/pET-22b-ORF-2 strain, a producer of capsid protein fragment (92–233 amino acid residues), was constructed. It was found that in the presence of 1 mM isopropyl-β-D-1-thiogalactopyranoside, the expression level of soluble truncated rCap was 35–40 mg/L 6 hours after induction. The expression product was tested for its specificity with indirect ELISA using whole-virion PCV-2-hyperimmunized porcine serum. It was shown that the positivity coefficient of producer strain cell lysates averaged to 4.34 (p &lt; 0.005). The recombinant rCap protein is suitable for serological diagnosis and is also of interest as a vaccine component, which is the goal of our further studies.

Mass Emigration and the Erosion of Liberal Democracy

Abstracts In many regions of the world, liberal politics is on the retreat. This development is usually explained with reference to inherently political phenomena. We propose an alternative explanation, linking democratic backsliding to deep-reaching demographic change caused by mass emigration. We argue that because migrants tend to be more politically liberal, their departure, if quantitatively significant, can hurt liberal democracy. Empirically, we focus on Central and Eastern Europe (CEE). Since 2004, the region has lost about 9 percent of its population due to migration to Western Europe. Drawing on data from 430,000 individuals and a panel analysis, we show that CEE migrants systematically hold more liberal values than non-migrants and that their exit went along with a deterioration of democracy in their home countries. Further analyses show that the mechanism we describe generalizes to various other world regions. Mass emigration may pose a challenge to democratic development in migrant-sending countries around the globe.

Global patterns and determinants of multiple facets of plant diversity

AbstractAimCombining different biodiversity dimensions can reveal new diversity patterns disclosing the relative roles of historical, environmental and anthropogenic factors in shaping global seed plant diversity.LocationGlobal.Time periodPresent.Major taxa studiedVascular plants.MethodsWe collated a database encompassing taxonomic (249,000 species), functional and phylogenetic information (34,694 species) of seed plants across different regions of the world. Species richness in each region was weighted accounting for their phylogenetic and functional distinctiveness, obtaining a new metric—μ‐diversity—which was modelled to disentangle the relative roles of historical factors such as climate variability since the Last Glacial Maximum (LGM), environmental features (e.g. actual evapotranspiration—AET) and anthropogenic factors (past and current).ResultsHigher μ‐diversity was observed in Papuasia, South East Asia, Australia and Central America, whereas the lowest values were primarily located in the Northern Hemisphere. Climate variability and AET were the most important determinants of μ‐diversity and individual diversity facets, whereas the importance of past human impacts (i.e. the onset of pastoralism) equated or exceeded those of the present ones.Main conclusionsOur integrative approach proved more sensitive in describing species diversity patterns. Few areas on Earth host high and unique proportions of multiple diversity facets and individual diversity facets contribute differently to μ‐diversity across continents. Historical climate stability and water‐energy dynamics strongly affect species diversity, but we also observed that past land‐use legacy may have influenced current plant diversity, which is under intense anthropogenic pressure, especially in Asia as well as in Central and South America.

Revision of the plesiosaur Polycotylus sopozkoi from the Southern Urals (Russia) confirms the wide distribution of Polycotylus in the Late Cretaceous of the Northern Hemisphere

Polycotylids are among the most common plesiosaurians of the Late Cretaceous, however, in Eurasia their findings are rare and fragmentary. In 2016, a partial polycotylid skeleton from the Upper Cretaceous of the Izhberda quarry in the Southern Urals region was described by Efimov et al. as a new species, Polycotylus sopozkoi. Here we revise this holotype specimen and show that many features initially proposed to distinguish the species are the result of misinterpretations. However, P. sopozkoi is indeed referable to Polycotylus and is highly similar to its type species, P. latipinnis. Although only one distinctive trait of the species noted by Efimov et al., the protruding basioccipital tubera with deep carotid canals on their anterodorsal surface, is confirmed here, new observations revealed additional features that allow us to substantiate the validity of P. sopozkoi. The presence of Polycotylus in the Upper Cretaceous of North America and Eastern Europe highlights a wide distribution of some plesiosaurian genera and suggests caution in assumptions of ‘endemic’ plesiosaurian taxa in particular regions of the world.

Pediatric Subacute Sclerosing Panencephalitis: A Narrative Review on Measles and the Future of Vaccination.

Subacute sclerosing panencephalitis is a rare complication due to persistent measles infection, characterized by cognitive and motor deterioration. Because subacute sclerosing panencephalitis is considered a potentially fatal complication of measles and usually presents in young populations, particularly those with measles infection under the age of 2 years, new approaches to implement vaccination programs must be devised to help avoid the worsening of patient outcome. Until the disease is eradicated globally, children in all regions of the world remain at risk of measles infection and its respective complications, and therefore, the vaccine is considered the optimal preventative measure. The legacy of measles virus goes beyond the immediate complications. Our study, therefore, aims to provide a comprehensive review on the updated insights into subacute sclerosing panencephalitis as a complication, as well as the extent and future considerations pertaining to vaccination programs in the pediatric population.