This study investigates the explosion limits of ammonia (NH3) and the effect of three different active fuels, hydrogen (H2), natural gas (NG), and diethyl ether (C2H5OC2H5, DEE), on the explosive characteristics of NH3 through comprehensive chemical kinetics analysis. The results reveal that the explosion limits of NH3 exhibit the narrowest explosive range and display comparatively weakest explosive reactivity among the four fuels, presenting a monotonic changing trend. Reaction pathway analysis unveils that with increasing temperature, NH2 tends to oxidize more predominantly through the NH-N2H2-NNH-N2 pathway, while the conversion of NH2 to H2NO pathway decreases. Therefore, the introduction of active fuels significantly enhances the explosive reactivity of NH3. However, their impact under various temperature-pressure conditions presents nuanced and diversified characteristics. When a 0.5 % mole fraction of active fuel is added to NH3, DEE exhibits the most significant enhancement in medium to high-pressure conditions, while H2 predominates at low pressure, with NG consistently demonstrating the least pronounced enhancement. Upon the active fuel proportion being increased to 20 %, the promoting effect of DEE remains the most significant in the medium to high-pressure region, while NG has surpassed H2 as the secondary dominant fuel. In the low-pressure region, NH3-H2 still demonstrates the highest reactivity, followed by NH3-DEE, while NH3-NG exhibits the least reactivity. These findings provide valuable insights into the widespread utilization and scientific exploration of ammonia as a fuel source.