The purpose of this study was to estimate the economic impacts of Chinese incentive cruise tourists on three ports of call(Busan, Jeju, and Yeosu) using regional Input-Output (I-O) model. An onsite survey was conducted for 1,000 Chinese incentive cruise tourists to estimate per capita expenditure. Also, tourism sectoral multipliers were derived from the regional I-O tables for three ports of call in terms of output, income, value added, indirect tax, and employment. The survey results indicate that per capita expenditure for Chinese cruise tourists was estimated to be 1.15 million Won and spending on shopping represented the largest amount with 82.7% of per capita expenditure. The results of regional I-O models reveal that Chinese cruise tourism generated 21.7 billion Won of output impact, 5.6 billion Won of income impact, 12.7 billion Won of value-added impact, 0.6 billion Won of tax impact, and 564 jobs of employment impact, respectively. Busan generated the largest economic impact, followed by Jeju and Yeosu(Jeonnam).