Background: Chronic total occlusion (CTO) intervention requires specialised skill. While the risks of the retrograde approach require the procedure to be performed with onsite surgical backup, the antegrade approach is considered lower risk. In 2015 an “antegrade only” CTO program was established at Mackay Base Hospital (MBH). Methods: Specific guidelines have been implemented and are sub-divided into “Case Selection”, “Technical Considerations” and “Emergency Management”. Suitable case selection stipulates that only CTOs with a J-CTO score ≤ 3 are considered for intervention. A policy of “antegrade approach only” has been established. A time constraint of sixty minutes for wiring is allowed. Bilateral access is compulsory. The catheterisation laboratory must maintain stock of correct equipment including embolization devices and a pericardiocentesis kit. Results: Procedural success occurred in 15 of the 20 cases (75%). Mean age was 66.95 years (range 50 – 96 years). Mean J-CTO score was 1.73(range 0-3) for the successful cases and J-CTO score 3 for the rest. Mean procedure time was 133.85 ± 30.00 minutes. All cases required wire escalation. The complications were a branch dissection and a wire perforation, neither with consequences. There were no adverse events at one to six month follow-up. Of the five unsuccessful cases one required coronary bypass graft surgery, one underwent CTO intervention via a retrograde approach, one waiting for reattempt-CTO under general anaesthesia and two are for medical therapy. Conclusion: The CTO program established at MBH is feasible and safe without onsite surgical backup amid a success rate meeting the international standard.