Afghanistan seems to be sliding into chaos notwithstanding the initial euphoria that followed the toppling of the Taliban regime. The long-term stability of Afghanistan is mainly contingent upon its integration in a regional cooperative framework. The Afghanistan Compact adopted at the London Conference in January-February 2006 identified regional cooperation as a main plank of the international community's reconstruction strategy. However, not all stakeholders in the region share similar perceptions or interests in promoting regional cooperation. This article seeks to examine whether regional cooperation in South Asia could be an effective mechanism to bring in long-term stability in Afghanistan. Will regional cooperation augment Afghanistan's capacity to deliver basic needs to the Afghan people? Would its entry into the South Asian fold contribute to peace in that country?