Primary Non Hodgkin’s lymphoma arising in the parotid glands are very uncommon, although 80% of all salivary gland lymphomas, appear in parotid and are classified as extranodal Non Hodgkin’s lymphoma. The ages of the patients ranged from 25 to 80 years (average 55.0 years) and the male to female ratio was 1.9:1. The 5-year-survival rate was 54%. Presenting symptoms were painless or painful mass in the parotid gland region. Some of the patients had facial nerve paralysis. It seems to be difficult to diagnose malignant lymphomas of the salivary glands preoperatively, because an open biopsy of the salivary glands is generally contraindicated. But the preoperative early diagnosis is essential in these cases to avoid an unnecessary radical procedure as well as to have a beneficial effect on the prognosis. We present one cases with a painless swelling of the cheek region. But failed to diagnose malignant lymphoma in the parotid gland preoperatively. So the tumors were treated surgically and an open biopsy of the parotid gland tumor was performed for the purpose of diagnosis. We describe one case of primary Non Hodgkin’s lymphoma of the parotid gland and review the literature of this condition. (J Clinical Otolaryngol 2005;16:136-139)