To protect the beauty and diversity of Quirino from the impacts of natural and human-made disasters, the call for sustainable and regenerative developments strengthens. With the introduction of permaculture in the province, it can serve as a framework for these developments. As such, the study seeks to showcase the potentials of permaculture by integrating its principles in the landscape design of Faraon Integrated Farm, as it aims to be a sustainable and regenerative agricultural eco-park. To achieve its goal, a series of literature studies, analyses, and conceptualization was conducted to identify the areas where permaculture can be incorporated. As a result, a permaculture-based landscape design of a sustainable and regenerative agricultural eco-park with a closed-loop system is developed. The eco-park was divided into six (6) permaculture zones, arranged according to the amount of attention it needs, consisting of areas chosen and designed based on the twelve (12) permaculture principles. To improve its sustainability and regenerative capacity, various technologies, practices, and techniques were also incorporated into the design, such as intercropping, use of natural farming inputs, vermicomposting, rainwater harvester & catchment, and utilization of renewable sources of energy. By imitating the Earth’s natural processes and relationships, permaculture can create sustainable and regenerative developments that could preserve and enhance the natural environment.