Regeneration Of Areas Research Articles

Synthesis, characterisation and functionalization of Hercynite nanoparticles for improved antibacterial activity

Hercynite i.e.,FeAl2O4 is an earth-abundant spinel mineral with a cubic crystal structure and belongs to the normal spinel ferrites possessing optical absorption in the visible range as well as superior magnetic and thermal properties. Herein, we synthesized nanosized FeAl2O4 where the citric acid-mediated sol–gel auto-combustion method was employed to achieve its pure phase and studied its physicochemical properties. Furthermore, the superior colloidal dispersion stability of the FeAl2O4 nanoparticles was achieved required for antibacterial activity and standardised via post-synthesis surface functionalisation using amino-propyl-triethoxysilane (APTES). We further characterised the material using states of art characterisation techniques for their structural, morphological, optical and thermal properties. Finally, the antibacterial activity of pure and surface functionalised FeAl2O4 nanoparticles was investigated against the Escherichia coli (E. coli) strain. We observed good penetration of surface functionalised FeAl2O4 nanoparticles into the bacterial membranes due to the high degree of dispersion achieved via cationic surface charge. Conclusively, a key finding of this study is the enhanced antibacterial properties of surface functionalised FeAl2O4 nanoparticles for the concentration of 31 µg/mL compared to pure FeAl2O4 nanoparticles at 62 µg/mL. This study has great relevance in the area of wound healing and tissue regeneration in the future.

The Regulatory Role of miRNAs in Zebrafish Fin Regeneration

Since Teleostei fins have a strong regenerative capacity, further research was conducted on the regulation of gene expression during fin regeneration. This research focuses on miRNA, which is a key post-transcriptional regulatory molecule. In this study, a miRNA library for the fin regeneration of zebrafish was constructed to reveal the differential expression of miRNA during fin regeneration and to explore the regulatory pathway for fin regeneration. Following the injection of miRNA agomir into zebrafish, the proliferation of blastema cells and the overall fin regeneration area were significantly reduced. It was observed that the miRNAs impaired blastocyte formation by affecting fin regeneration through the inhibition of the expressions of genes and proteins associated with blastocyte formation (including yap1 and Smad1/5/9), which is an effect associated with the Hippo pathway. Furthermore, it has been demonstrated that miRNAs can impair the patterns and mineralization of newly formed fin rays. The miRNAs influenced fin regeneration by inhibiting the expression of a range of bone-related genes and proteins in osteoblast lineages, including sp7, runx2a, and runx2b. This study provides a valuable reference for the further exploration of morphological bone reconstruction in aquatic vertebrates.

Mangrove forest regeneration age map and drivers of restoration success in Gulf Cooperation Council countries from satellite imagery

Mangrove forests are found across the Gulf Cooperation Council (GCC) region despite challenging environmental extremes, including highly variable temperatures and hypersalinity. Understanding the biophysical and anthropogenic factors that influence mangrove forest growth is key to locate suitable areas for regeneration and afforestation activities. The main objectives of this study were to develop a mangrove forest regeneration age map that represents the age of all the existing secondary mangroves in the past 37 years (1986–2023). Long-term Landsat satellite imagery, the random forest classification algorithm, and logistic regression analyses were used to identify the existing secondary mangroves and determine the underlying drivers that contribute to the successful afforestation of mangroves in the region. Our results showed that only around 8.5% of secondary mangrove forests in the GCC region were older than 30 years, with mangroves younger than 5 years being the most abundant age class (41.3%). Saudi Arabia and Oman have the highest percentages of young mangroves, while relatively older secondary mangrove forests were most common in Bahrain, Qatar, and UAE. The current trends in overall mangrove area show that the UAE and Saudi Arabia have the largest total mangrove area among the GCC countries, followed by Qatar, Oman, Bahrain, and Kuwait. The results of the stepwise logistic regression show that the main drivers that influence mangrove regeneration are lower elevation, lower slope, higher available soil moisture, lower average temperatures, higher precipitation, greater proximity to freshwater sources, lower population density and greater distance from agricultural and urban areas. Our results aim to offer support to decision-making in selecting optimal areas for new planting initiatives in the region.

Soil fauna changing in after‐pine harvesting's areas along a temporal gradient of Atlantic Forest regeneration

AbstractMonoculture of pine alters the soil fauna community structure, but forest farms, mixed with natural areas, are restoring the original vegetation to protect, the diversity and ecosystem functions. In restoration initiatives it is necessary to consider the soil fauna. Thus, the aim of this study was to investigate how the process of restoration of the soil community occurs over time in areas after pine harvesting. Areas in natural regeneration with 4 and 10 years, pine plantations adjacent to these areas (representing previous use), and areas of natural forest (reference) were evaluated, it was evaluated three areas per treatment, with six sampling points spaced 30 m apart, totalling 18 sampling points for each treatment (n = 18). Soil mesofauna and macrofauna were collected through soil monoliths and pitfall traps. The comparison of the statistical analysis was to check for changes in the soil fauna over time (4 and 10 years) compared with that observed in secondary forest areas. The study showed that, along the natural regeneration time (4 and 10 years), it was observed increments in the diversity and evenness of the soil community and a reduction in the dominance of groups like Formicidae and increases in the community structure complexity with the resurgence of micropredators/regulators (Collembola and Acari), litter transformers (Oligochaeta, Diplopoda, Blattodea, Coleoptera (Larva), Diptera (Larva) and Coleoptera) and predators (Pseudoscorpiones, Opiliones, Symphyla and Coleoptera) after 10 years of natural regeneration, the areas have already recovered groups with important ecosystem functions, but are not yet at the level of abundance, functional diversity and community structure of native forest areas. The 4‐ and 10‐year regeneration areas present major number of soil fauna groups of native forest (20 groups in regeneration areas and 17 in the native forest areas). Even so, the forest showed a major complexity of soil fauna community structure, evidenced by the diversity. This study contributes to the understanding of natural regeneration for soil fauna along a temporal gradient and these findings can guide the conservation of regional soil fauna diversity.

Effect of soil management on carbon stock and soil aggregation in an area of natural regeneration and surrounding systems in the Atlantic Forest biome

This study aimed to quantify total organic carbon (TOC), carbon of humic substances (HS), and their stocks and evaluate the soil structural stability of areas with different uses under sandy loam soil texture. Soil samples were collected from managed areas and a reference area: Permanent Pasture (PP), No-Till (NT), Private Natural Heritage Reserve in the process of natural regeneration (PNHR) and Native Forest (FN). Dry mass analysis, carbon stock quantification, chemical fractionation of soil organic matter and soil aggregation were carried out. The NF area had the highest deposition of litter mass (ML). The PP and NT areas had the highest bulk density (Bd). TOC and Stock-C contents were higher in PNHR, followed by NF, and stratification index (STRATI) was also higher in the regeneration area. The NT, PNHR, and NF areas had a higher proportion of carbon fulvic acid fraction (C-FA) than carbon humic acid fraction (C-HA), but the fraction with the highest representation in all areas was carbon humin fraction (C-HUM). The PP, PNHR, and NF areas obtained the best aggregate stability indicators, as well as a higher proportion of macroaggregates, with the NT area having low aggregate stability. Recovery of C contents was observed in recent years in the area of PNHR, leading to a greater storage of C, which shows a quantitative recovery of C in the soil in this area after four years of natural regeneration. Furthermore, the PP and NT areas present a lower capacity for C sequestration, mainly due to the management conditions. Keywords: aggregate stability, climate change, crop production, soil quality.

Improvement of polycaprolactone and polyethylene glycol flexible polymeric film enhances bone volume and interconnectivity in bone lesions through transport of mesenchymal stem cells differentiated to osteoblasts

AbstractBone fractures are one of the most common types of human injury. This study aimed to create a synergistic action of polymeric films (PFs) based on polycaprolactone (PCL) and polyethylene glycol (PEG) (PCL‐PEG‐PFs) deposited by casting, combined with mesenchymal stem cells (MSCs) that differentiate into osteoblasts for bone regeneration. In vitro experiments indicated that the PCL‐PEG‐PFs (70:30) exhibited low cytotoxicity and enhanced cell adhesion capacity. In vivo studies were performed to evaluate the bone regeneration capacity of PFs with MSCs that adhered to and differentiated into osteoblasts. The cell differentiation process was carried out for 18 days in cell culture for subsequent implantation in the calvaria of male C57BL/6J mice, which remained in contact with the bone lesion for another 14 days. In vivo studies indicated that the application of PCL‐PEG‐PFs (70:30) increased the bone surface area to the total volume, with significant regeneration areas (levels greater than 25%) and interconnectivity compared to the control. In addition, the generated tissue presented cells with a morphology comparable to that of the peripheral tissue of the injured region, indicating a positive synergistic interaction between PCL‐PEG‐PFs (70:30) and MSCs differentiated into osteoblasts in contact with the bone lesion.

SOX9 functionalized scaffolds as a barrier to against cartilage fibrosis

Hyaline cartilage regeneration will bring evangel to millions of people suffered from cartilage diseases. However, uncontrollable cartilage fibrosis and matrix mineralization are the primary causes of cartilage regeneration failure in many tissue engineering scaffolds. This study presents a new attempt to avoid endochondral ossification or fibrosis in cartilage regeneration therapy by establishing biochemical regulatory area. Here, SOX9 expression plasmids are assembled in cellulose gels by chitosan gene vectors to fabricate SOX9+ functionalized scaffolds. RT-qPCR, western blot and biochemical analysis all show that the SOX9 reinforcement strategy can enhance chondrogenic specific proteins expression and promote GAG production. Notably, the interference from SOX9 has resisted osteogenic inducing significantly, showing an inhibition of COL1, OPN and OC production, and the inhibition efficiency was about 58.4 %, 22.8 % and 76.9 % respectively. In vivo study, implantation of these scaffolds with BMSCs can induce chondrogenic differentiation and resist endochondral ossification effectively. Moreover, specific SOX9+ functionalized area of the gel exhibited the resistance to matrix mineralization, indicating the special biochemical functional area for cartilage regeneration. These results indicate that this strategy is effective for promoting the hyaline cartilage regeneration and avoiding cartilage fibrosis, which provides a new insight to the future development of cartilage regeneration scaffolds.

Biomechanical Finite Element Analysis of Bone Tissues with Different Scales in the Bone Regeneration Area after Scoliosis Surgery

Biomechanical Finite Element Analysis of Bone Tissues with Different Scales in the Bone Regeneration Area after Scoliosis Surgery

Rainfall and soil properties driver the temporal dynamics of arbuscular mycorrhizal fungal assemblages in a seasonally dry tropical forest

The Seasonally Dry Tropical Forests (SDTF), distributed from Mexico to northern Argentina, are habitat to a unique biodiversity. Among these forests, the Caatinga stands out, occupying a large part of the Brazilian Northeast and is subject to cycles of anthropic disturbance and abandonment of exploited areas. Understanding how microbial communities respond to environmental changes is crucial, especially considering the various ecosystem services provided by microorganisms. Among soil microorganisms, arbuscular mycorrhizal fungi (AMF) play a significant role in the maintenance of terrestrial ecosystems. In this study, we aimed to evaluate the structure, composition, and distribution of AMF assemblages, as well as their main drivers, in regeneration areas of the Caatinga. Soil samples were collected in the Catimbau National Park (Pernambuco State), including an old-growth forest representing undisturbed areas, and in early, intermediate, and late regeneration areas. The composition of AMF assemblages differed among regenerating areas and old-growth forest, but their distribution is not related and conditioned to plant assemblages. Instead, soil properties and rainfall are the main factors structuring these assemblages in SDTF. A total of 83 taxa of AMF were identified. Glomus and Acaulospora, which exhibit respectively ruderal and stress-tolerant life strategies were the most abundant genera. The highest number of unique AMF species was recorded in the old-growth forest, contrasting with the late regeneration areas which had the lowest number. The results showed that deterministic processes (soil and rainfall) are structuring the AMF assemblages in areas under regeneration process in SDTF. Plants and AMF do not recover simultaneously over the evaluated regeneration times.

Vascular mimicry in zebrafish fin regeneration: how macrophages build new blood vessels

Vascular mimicry has been thoroughly investigated in tumor angiogenesis. In this study, we demonstrate for the first time that a process closely resembling tumor vascular mimicry is present during physiological blood vessel formation in tissue regeneration using the zebrafish fin regeneration assay. At the fin-regenerating front, vasculature is formed by mosaic blood vessels with endothelial-like cells possessing the morphological phenotype of a macrophage and co-expressing both endothelial and macrophage markers within single cells. Our data demonstrate that the vascular segments of the regenerating tissue expand, in part, through the transformation of adjacent macrophages into endothelial-like cells, forming functional, perfused channels and contributing to the de novo formation of microvasculature. Inhibiting the formation of tubular vascular-like structures by CVM-1118 prevents vascular mimicry and network formation resulting in a 70% shorter regeneration area with 60% reduced vessel growth and a complete absence of any signs of regeneration in half of the fin area. Additionally, this is associated with a significant reduction in macrophages. Furthermore, depleting macrophages using macrophage inhibitor PLX-3397, results in impaired tissue regeneration and blood vessel formation, namely a reduction in the regeneration area and vessel network by 75% in comparison to controls.

Energy Efficiency of Conifer Cones and Seed Extraction Residue Biomass

Sustainable forest management, which accounts for the multiple roles played by forests, includes seed collection from selected areas for forest renewal and regeneration. The process of harvesting conifer seeds generates considerable amounts of waste biomass that can be used as a source of energy to supplement the local solid fuel market. Therefore, their quality is an important consideration. The mass fraction of Scots pine seed extraction residues was determined in this study. The thermophysical properties and elemental composition of the residues and spent Norway spruce and European larch cones (after seed extraction) were evaluated. An analysis of Scots pine seed extraction residues revealed that only cones had practical application. They accounted for more than 99% of total residue biomass and were characterized by the lowest content of ash, sulfur, and chlorine. The calorific value of cones of the analyzed tree species ranged from 17.08 to 18.29 MJ kg−1, the chlorine content was 0.010–0.041% DM, and the sulfur content was 0.019–0.043% DM. Due to the specificity of the extraction process, the generated waste, including cones, had a very low moisture content of 6.86–10.02%, which significantly increased their value as solid fuel.

Refracture-related bone transport of tibia: technical notes and preliminary clinical results in nineteen cases.

Refracture is one of the main complications of bone transport, which brings additional physical and mental burden to surgeries and patients. We aimed to raise a new classification system of refracture-related bone transport based on the Simpson classification and to present our experience on treatment. This retrospective analysis included 19 patients with refracture-related bone transport (average age of 37.7years; 18 men). We developed a modified Simpson classification system to assist decision-making (conservative versus surgical). The ASAMI criteria were used to assess the outcomes at last follow-up. The mean follow-up was 12.3 ± 3.2months. Complete union was achieved in all patients, with no reinfection. Based on the modified Simpson classification, refracture was Ia type (within regeneration area) in three cases, Ib (collapsed fracture at the regeneration area) in one case, Ic (stress fracture) in three cases, II (at the junction between the regenerate and original bone) in one case, III (at the docking site) in nine cases, and V (at distant site) in two cases. Refracture was managed conservatively in six cases and surgically in 13 cases. Average time to bone union was 2.8 ± 1.2months in the conservative group versus 4.4 ± 1.4months in the surgery group. Assessment at the final follow-up using the ASAMI criteria revealed excellent bone result in all patients, excellent functional results in six patients (31.6%), and good functional results in 13 patients. The modified Simpson classification could include refracture at the docking site and stress fracture in the regeneration zone and provide some guidance in determining the appropriate treatment strategy.

Ligand-Selective Targeting of Macrophage Hydrogel Elicits Bone Immune-Stem Cell Endogenous Self-Healing Program to Promote Bone Regeneration.

Targeting macrophages can facilitate the site-specific repair of critical bone defects. Herein, a composite hydrogel, gelatin-Bletilla striata polysaccharide-mesoporous bioactive glass hydrogel (GBMgel), is constructed via the self-assembly of mesoporous bioactive glass on polysaccharide structures, through the Schiff base reaction. GBMgel can efficiently capture macrophages and drive the recruitment of seed stem cells and vascular budding required for regeneration in the early stages of bone injury, and the observed sustained release of inorganic silicon ions further enhances bone matrix deposition, mineralization, and vascular maturation. Moreover, the use of macrophage-depleted rat calvarial defect models further confirms that GBMgel, with ligand-selective macrophage targeting, increases the bone regeneration area and the proportion of mature bone. Mechanistic studies reveal that GBMgel upregulates the TLR4/NF-κB and MAPK macrophage pathways in the early stages and the JAK/STAT3 pathway in the later stages; thus initiating macrophage polarization at different time points. In conclusion, this study is based on the endogenous self-healing properties of bone macrophages, which enhances stem cell homing, and provides a research and theoretical basis upon which bone tissue can be reshaped and regenerated using the body's immune power, providing a new strategy for the treatment of critical bone defects.

Assessment of Edible Woody Plants’ Diversity, Their Threats, and Local People’s Perception in Borecha Woreda of Buno Bedele Zone, Southwestern Ethiopia

Edible woody plants play an essential role in ensuring the food and livelihood security of communities. However, the management practice and diversity of those plants are declined, particularly in an urbanizing world, due to a lack of traditional awareness among the people. This research identified edible woody plants’ diversity, their threats, and local people’s perception in Borecha woreda of Buno Bedele Zone, southwestern Ethiopia. Data on edible woody plants were gathered through interviews with 105 households (67 men and 38 women) between the ages of 21 and 90. Structured and semistructured questionnaires were used to obtain the data from informants. The collected data were analyzed using descriptive statistics in Statistical Package for the Social Sciences (SPSS) software. Results showed significant differences (P<0.05) between the number of edible woody plants reported by age and literacy level of respondents. Forty-three species of edible woody plants, belonging to 34 genera and 24 families, were identified. Fruits (79.1%), roots (14%), leaves (2.3%), stems (2.3%), and seeds (2.3%) were identified as the edible parts of these plants. Fruits are the most edible plant part usually consumed fresh without cooking in the study area. The identified plants have a variety of growth forms: shrubs (49%), trees (37%), and lianas (14%) respectively. The most common plant growth forms in the study site were shrubs. In the study area, agricultural expansion, overharvesting, and lack of natural regeneration were the major threats to edible woody plants. In the study area, cutting for constructions was the primary hazard to edible woody plants. In situ and ex situ conservation strategies and efforts of plantation practices in the agricultural landscape are needed for sustaining the edible woody plants in the study area.

도시재생사업의 성과측정에 관한 연구

The urban regeneration project started under the Park Geun-hye administration and was promoted more heavily as a New Deal project under the Moon Jae-in administration. However, as the urban regeneration project progressed, problems arose that residents could not feel due to poor implementation performance and low execution ability. Accordingly, in this study, in order to establish and achieve the goals of the urban regeneration revitalization plan, a management system and performance indicators for monitoring, evaluation, and feedback are presented to systematically and comprehensively manage everything from plan establishment to performance and effect derivation, and a resident satisfaction survey to measure performance. We conducted an investigation. In order to accurately measure performance, the ‘Comprehensive Performance Index’ presented by the central government was used as a common indicator, and the ‘Local Government Performance Index’ was comprehensively analyzed and used as an auxiliary indicator. In this study, research was conducted targeting the ‘Jeonju Station Area Urban Regeneration Area’, which is currently under construction, to select indicators for performance measurement, and practical data was presented in relation to the research method.

도시재생사업의 초기사업비 및 기반시설비용 조달을 위한 조세담보부금융(TIF) 규모 추정에 관한 연구

Tax Increment Financing (TIF) is the process of raising funds through the increase of taxes in future business areas. The local government treasury department finance is built by the increase of future tax revenue due to the real estate price rise in the urban regeneration area, TIF has been used in the US especially today. Because urban regeneration projects can be said to be achieved not only during the project period but also after the end of the project period, in order to finance the local taxation as a collateral, it is necessary to induce the interest of the local residents to be in charge of business management. In this study, We found the possibility of provision for urban regeneration total costs, which are essential for the sustainability and continuity of urban regeneration areas, through the financial simulation for the case region. As compared with urban regeneartion, in the extensive rebuilding apartment houses and residential area redevelopment process, it is difficult for the stakeholder to bear urban regeneration costs additionally, due to the huge land development land and financial donation. This research result will motivate the Tax Increment Financing to proceed smoothly during the urban regeneration project period longer than we expect.

Enhanced Fat Graft Viability and Remodeling Using a Helium-based Radiofrequency Device to Prepare the Recipient Site

BackgroundImprovements to autologous fat grafting for soft tissue augmentation are needed to overcome the unpredictable volume retention. Approaches such as fat harvesting and processing, injection technique, preparation of the recipient site, and supplemental biologics are topics of ongoing research. Here, an energy-based device was investigated as a stimulatory tool for recipient site preparation for improving fat graft retention.ObjectiveThe objective was to measure the stimulatory responses in fat grafts after 4 weeks when using a helium-based radiofrequency device to pretreat the recipient tissue.MethodsUsing an autologous fat grafting mouse model, the inguinal fat pad was grafted in a small cranial pocket after either a saline injection alone (control) or a saline injection followed by pretreatment (treated). The fat pad was resected after 4 weeks, sectioned and stained with immunofluorescence markers to investigate tissue remodeling.ResultsPretreatment resulted in higher viability of adipocytes, a higher concentration of viable ASCs in areas of adipose tissue regeneration, and localized macrophages in the areas of regeneration when compared to the control. There was no observable difference in vascularity or angiogenesis. The staining for ASCs was higher in the pretreated group in comparison with the control group (5.0% vs. 3.3%, p=0.36) when using a pixel classifier in QuPath in the viable adipose tissue regions.ConclusionsThe use of a helium-based radiofrequency device as a pretreatment tool appears to increase the viability of the adipose tissue likely due to higher concentration of ASCs. The apparent increase in viable ASCs may be due to enhanced proliferation or paracrine recruitment of these cells in response to the helium-based radiofrequency treatment.No Level AssignedThis journal requires that authors assign a level of evidence to each submission to which Evidence-Based Medicine rankings are applicable. This excludes Review Articles, Book Reviews, and manuscripts that concern Basic Science, Animal Studies, Cadaver Studies, and Experimental Studies. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.Bullet List of Important Points:Pretreatment of the fat graft recipient site increases the viability of the adipose tissue after 4 weeks in comparison with the control grafts.The increased viability is likely due to the observed increase in adipose-derived stem cells in the pretreated group.Pretreatment enhanced the adipose tissue remodeling as colocalization of adipose-derived stem cells and macrophages showed an active remodeling, whereas the control group exhibited more necrotic and fibrotic tissue.

Spatial and functional structure of the population area in plants – the need for differentiation

Considering the population as a homogeneous phenomenon in the process of studying its demography devalues the principle of systemic analysis. Therefore, there is a need to improve methods for identifying intra-population components and clari­fying their role in the functioning of the population. This article is devoted to detailing the spatial (and demographic) structure of the population. Within the area occupied by the population, it is necessary to differentiate components that differ significantly in terms of both environmental conditions and population characteristics. Structuring of the population area is proposed in accordance with localization of different functional groups. Namely, it is proposed to distinguish the potential, total, realized, effective and regeneration areas of the population. The potential area refers to the part of the territory with favorable ecological and phytocenotic conditions for the existence of the population. It includes the surrounding territory, which is potentially suitable for colonization. The total area of the population spans the territory within the boundaries of which its individuals of different age states are distributed. The realized area is the total area occupied by population loci and population individuals. It does not include significant unoccupied spaces between loci and individuals. The effective area is part of the territory where reproductive plants are located. The regenerative area refers to the part of the territory where seed sprouts exist and develop to the state of adult reproductive plants. Effective and regenerative areas are of particular importance for preserving rare perennial plant species in nature. They differ significantly in their conditions and volu­mes from the total and realized areas. Besides, they are mostly concentrated locally, not distributed over the entire population area. Differentiation of the structure of the population area into individual components is, in our opinion, a promising methodical approach to ecological research. It is important to differentiate the accounting of various structural components of the population area during population monitoring.

A Study on the Effects of Emotional and Cognitive Experiences through Urban Regeneration Area on the Regeneration Area of Attachment and Brand Equity: Focusing on Gungchon Village, Boryeong-si, Chung cheong nam-do

A Study on the Effects of Emotional and Cognitive Experiences through Urban Regeneration Area on the Regeneration Area of Attachment and Brand Equity: Focusing on Gungchon Village, Boryeong-si, Chung cheong nam-do

도시재생 지역 내 공동체 의식과 삶의 질의 관계에서 갈등대처의 조절효과

The purpose of this study was to explore the preferred parking solution model for residents of Yeonmu-dong, Suwon-si, Gyeonggi-do, in order to address conflicts arising from parking problems and to develop parking relief systems tailored to local characteristics. Yeonmu-dong is situated in an urban regeneration area within the old city center, characterized by low-rise residential density, a high percentage of elderly residents, and a significant number of long-term residents who have lived there for more than a decade. Our primary objective was to investigate whether conflict resolution strategies have a moderating impact on the relationship between residents' sense of community and their quality of life.
 To achieve our research objectives, we gathered academic literature related to urban regeneration, analyzed statistical data from public institutions, and conducted a survey of local residents. We then conducted statistical analysis, including descriptive statistics, group difference analysis, and hierarchical regression analysis, to analyze the survey data using SPSS 27 statistical techniques.
 The analysis revealed several key findings. Firstly, residents expressed a preference for parking solutions falling under the categories of 'citizen participation type' and 'existing facility utilization type' to alleviate parking space shortages. Some of the suggested alternatives included 'developing parking lots by purchasing old houses,' 'having parking facilities at home,' 'utilizing public facilities such as school playgrounds,' and 'making use of vacant land.' Secondly, although local residents exhibited a relatively high sense of community and employed positive conflict resolution methods, their overall quality of life was somewhat low. Lastly, the relationship between a positive sense of community and a negative quality of life was found to be influenced by the type of conflict resolution strategies employed.
 In conclusion, while the presence of a significant elderly population in the region can be advantageous, it is important to address the declining number of young residents, which can hinder regional development. Therefore, policies aimed at attracting younger individuals should be considered, along with initiatives to promote privately-led community councils. Furthermore, it was observed that a higher sense of community among local residents positively affects their quality of life. To enhance this effect, policy efforts should include providing conflict management education for local residents.