Mixed-refrigerant Joule-Thomson refrigeration (MJTR) is the dominant technology for cooling distributed-temperature heat loads, such as natural gas liquefaction. The mixed refrigerant determines the refrigeration cycle's performance (cooling temperature and efficiency, etc.). However, the current mathematical methods for mixed refrigerants’ optimization are time-consuming. In this paper, a mixed refrigerant optimization method based on the effective refrigeration effect is proposed. The equivalent enthalpy (EH˙) of temperature difference is proposed to predict the temperature difference distribution in the recuperator without cycle simulation. The optimization objective is to optimizeEH˙much closer to zero. In each step, only one component is adjusted, which is determined through its’ effective refrigeration effect, i.e., the partial molar enthalpy difference, in the optimization process. This method is applied to natural gas liquefaction (LNG), nitrogen liquefaction (LN2) and Cryo-compressed hydrogen storage (CcH2) systems. The exergy efficiencies in LNG, LN2 and CcH2 systems are 0.462, 0.390 and 0.421, which increase about 23.9%, 22.4% and 23.5% compared to references, respectively. The optimization time is less than 10 min per case in this study. This method can optimize mixed refrigerants in MJTR cooling various distributed-temperature heat loads.
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