I WOULD like to suggest an alternative to the mechanism suggested by Gally and Edelman1 for the joining of the V gene to the C gene. This mechanism has three principal features: (1) no “cross-over” event (for excision and integration) is required; (2) the joined product, the coupled VC into one gene, could either be an RNA or a DNA molecule; and (3) the C gene in its joining end must have a few redundant bases which are almost identical to the joining end of the V gene.