This study explores the socio-economic determinants of infant mortality in China through two empirical models, employing linear regression analysis on data from 2010 to 2020. The first model examines the impact of female labor force participation, GDP per capita, health expenditure, and fertility rates on infant mortality. Findings indicate significant negative associations between infant mortality and both female labor force participation and GDP per capita, while health expenditure did not show a significant impact. The second model introduces an interaction term between female labor force participation and GDP, highlighting the nuanced relationship between economic growth and gender dynamics in influencing infant mortality. Results from this model suggest that the beneficial impact of female labor force participation on reducing infant mortality is more pronounced with higher GDP growth. Despite facing limitations such as small sample size and multicollinearity, this research underscores the importance of economic and gender factors in improving infant health outcomes in China, suggesting avenues for further study with more comprehensive models and variables.