Reduction Strategies Research Articles

The Züri Can study: Can regulated cannabis sales promote lower-risk cannabis use? Mini-review and study protocol

Background and AimsRecreational use of cannabis is illegal in most countries. Despite this, it is the third most commonly used psychoactive substance worldwide. As a result of this discrepancy, a growing number of countries have begun to reassess their legal approach to cannabis in recent years. While the health risks of cannabis and potential harm reduction measures are increasingly well understood, there are still significant gaps in knowledge about which regulatory and supply models are effective in promoting lower-risk cannabis use.In this paper, we outline the Züri Can study, which implements and evaluates a regulatory framework for cannabis sales in the city of Zurich, Switzerland, between 2023 and 2026. In addition, we illustrate how the study addresses current knowledge gaps to provide further insight into the potential future regulation of cannabis in Switzerland.To embed the study in the present scientific and political context, we first provide a brief overview of the state of knowledge on cannabis-related health risks and means of reducing them, along with lessons learned from other countries that have implemented varying regulatory systems. Design and Measurements2,100 participants will be able to legally purchase cannabis either at a pharmacy, a cannabis social club, or the municipal drug information center over a three-year period. As part of this observational study, participants will be evaluated regarding their cannabis use habits and motives, their knowledge of lower-risk use, and their mental and physical health, among other parameters.Established harm reduction strategies are implemented as an integral part of the study design. CommentsThe study will contribute to a better understanding of the impact of different cannabis distribution models on cannabis use patterns and related health outcomes. The results are expected to assist Swiss and international policy makers in developing evidence-based and public health-oriented regulatory frameworks for cannabis.

Unraveling the nexus: Exploring Malaysia's research trends in advancing UN SDG 1

This study examines Malaysia's poverty rate with respect to SDG poverty reduction targets, the specific policies and programmes implemented to address poverty within the SDGs' framework, and the challenges and obstacles faced by Malaysia in achieving SDG poverty reduction targets. Despite Malaysia's significant achievements in reducing the aggregate poverty rate from 8.9% in 1995 to 1.7% in 2012, the country still faces poverty pockets in rural areas, specific states or regions, ethnic groups, and urban areas. These figures underscore the importance of targeted spatial planning and policy implementation to eradicate poverty effectively. Utilising a bibliometric analysis of the SCOPUS database, this study identifies key indicators of poverty in Malaysia based on Sustainable Development Goals (SDGs). Furthermore, Malaysia's alignment with SDG Poverty Reduction Targets comprises its poverty eradication programme, which has successfully reduced the incidence of poverty from 49.3% in 1970 to 8.7% in 1995 and then to 0.4% in 2016. Despite this overall reduction in poverty, the reality of relative poverty and the poverty gap is increasing, indicating the need for a more comprehensive approach to address poverty and inequality. The Malaysian government has prioritised the provision of employment opportunities, household income, infrastructure, and facilities. However, challenges remain in identifying the infrastructure and facilities capable of providing maximum services for all levels of society, particularly in rural areas. The bibliometric analysis highlights the expanding sphere of SDG poverty reduction research in Malaysia, which reflects the country's intricate socio-economic landscape, particularly after the COVID-19 pandemic. Increasing academic output and impressive citation metrics indicate a strong scholarly interest in addressing poverty through various approaches. However, the emerging nature of this field warrants further exploration of the socio-legal and political factors that impact poverty alleviation. By focusing on the local context and incorporating grey literature into research, discussions can be enhanced, enriching the applicability of poverty reduction strategies and contributing to global sustainable development discourses.

Innovative strategy for corrosion protection and drag reduction in coiled tubing: Design, fabrication, and performance evaluation

To improve the anti-corrosive and drag-reducing properties of 70 carbon steel coiled tubing and extend its service life, we presented an innovative approach involving composite electroplating. This method allows for the deposition of high-performance, anti-corrosive, and drag-reducing coatings on the inner walls of coiled tubing. And a continuous, uniform, and dense Ni-Co-Al2O3 coating was successfully prepared on the inner wall of coiled tubing. This economically viable technique was systematically applicable in industrial settings for enhancing drag reduction and corrosion resistance in continuous petroleum pipelines, offering a practical solution for manufacturing functional coatings with desirable properties. Furthermore, considering the inhibitory effect of Co(OH)2 on Ni deposition, we developed a novel anomalous co-deposition model for Ni-Co binary alloys. The simulation results using the COMSOL® demonstrated a high correlation with the experimental data, underscoring the model as effective for controlling and predicting the composition and structure of Ni-Co coatings.

Dynamic Multi-Factor Correlation Analysis for Prediction of Provincial Carbon Emissions in China’s Bohai Rim Region

This study presents a dynamic multi-factor correlation analysis method designed to predict provincial carbon dioxide emissions (CDE) within China’s Bohai Rim region, including Tianjin, Hebei, Shandong, and Liaoning. By employing the sliding window technique, dynamic correlation curves are computed between various influencing factors and CDE at different time intervals, thereby facilitating the identification of key feature attributes. A novel metric, the Consistency Index of Influencing Factors (CIIF), is introduced to evaluate the consistency of these factors across regions. Furthermore, the Accurate Predictive Capability Indicator (APCI) is defined to measure the impact of different feature categories on the prediction accuracy. The findings reveal that models relying on a single influencing factor exhibit limited accuracy, whereas combining multiple factors with diverse correlation features significantly improves the prediction accuracy. This study introduces a refined analytical framework and a comprehensive indicator system for CDE prediction. It enhances the understanding of the complex factors that influence CDE and provides a scientific rationale for implementing effective emission reduction strategies.

"A way to liberate myself": A qualitative study of perceived benefits and risks of chemsex among gay, bisexual, and other men who have sex with men in Almaty, Kazakhstan

BackgroundIn Kazakhstan, the HIV epidemic has a significant impact on marginalized groups such as gay, bisexual and other men who have sex with men (GBMSM), exacerbated by homophobic attitudes (in society) and (resulting) minority stress. This stress often leads to coping behaviors such as chemsex - the use of synthetic stimulants to enhance sexual experiences. Our study explores the motivations and perceived risks associated with chemsex among GBMSM in Almaty. MethodsWe conducted semi-structured in-depth interviews with 21 chemsex participants self-identified as GBMSM in Almaty, Kazakhstan. Participants were recruited through community-based organizations to ensure a diverse sample in terms of age and ethnicity. Thematic analysis was used to identify key themes related to motivations and risks. ResultsParticipants practiced chemsex to seek liberation from societal norms and personal inhibitions, increase sexual pleasure, and escape daily stressors. Chemsex sessions provided intensified sexual experiences, emotional comfort, and social connections, challenging constraints on sexual behavior. Participants recognized significant risks, including mental and physical health issues, social stigma, and violence victimisation. Despite these risks, the desire for the perceived benefits of chemsex, particularly feelings of freedom and happiness, underscored its appeal. ConclusionsThe study reveals a complex dynamic in which chemsex serves as a coping mechanism for minority stress, a source of sexual liberation, and a social connector for GBMSM in Kazakhstan, while also posing significant health risks. These findings emphasize the need for targeted harm reduction strategies, mental health support, and community-building efforts that are responsive to the experiences and needs of GBMSM who engage in chemsex.

Waste to wealth: Polyhydroxyalkanoates (PHA) production from food waste for a sustainable packaging paradigm

The growing demand for sustainable food packaging and the increasing concerns regarding environmental pollution have driven interest in biodegradable materials. This paper presents an in-depth review of the production of Polyhydroxyalkanoates (PHA), a biodegradable polymer, from food waste. PHA-based bioplastics, particularly when derived from low-cost carbon sources such as volatile fatty acids (VFAs) and waste oils, offer a promising solution for reducing plastic waste and enhancing food packaging sustainability. Through optimization of microbial fermentation processes, PHA production can achieve significant efficiency improvements, with yields reaching up to 87 % PHA content under ideal conditions. This review highlights the technical advancements in using PHA for food packaging, emphasizing its biodegradability, biocompatibility, and potential to serve as a biodegradable alternative to petroleum-based plastics. However, challenges such as high production costs, mechanical limitations, and the need for scalability remain barriers to industrial adoption. The future of PHA in food packaging hinges on overcoming these challenges through further research and innovation in production techniques, material properties, and cost reduction strategies, along with necessary legislative support to promote widespread use.

Development, Evaluation, and Initial Findings of New York State Department of Health Community Drug Checking Pilot Programs.

The illicit drug landscape in the United States is dynamic, featuring a risky and erratic drug supply. Drug checking programs (DCP) have been successfully implemented and studied extensively in Canada and Europe but are scarce in the United States. Integrating DCP at harm reduction programs provides an opportunity to engage people at the point-of-care and deliver a combination of harm reduction services, access to healthcare services, and linkages to treatment. The New York State Department of Health (NYSDOH) developed and supports operation of 8 pilot community DCP sites throughout the state. The DCP were trained to utilize Fourier-transform infrared spectroscopy (FTIR) technology to deliver real-time results to participants. The NYSDOH community DCP pilot began development in 2022. Partnerships were formed across multiple domains including other DCP, universities, forensic laboratories, syringe service and harm reduction programs, and legal and regulatory offices within the NYSDOH. The first pilot sites began operating in mid-2023 and program expansion is on-going. Evaluation staff were extensively engaged in development and implementation phases. Qualitative evaluation focused on barriers, facilitators, and lessons learned from program staff and technicians. Quantitative evidence was gathered to assess the reach of the DCP and accuracy of results attained by drug checking technicians during their training periods. Drug checking results helped characterize the illicit drug supply. Development and implementation of DCP in NYS was facilitated by strong partnerships across sectors including public health and harm reduction. DCP may involve diverse partners who do not regularly collaborate, and health departments are positioned to build relationships and convene partners for program implementation. Evaluation findings highlight the importance of facilitating on-going training and technical assistance to DCP for quality assurance. The initial successes and lessons learned from the NYSDOH DCP demonstrate state public health departments' ability to successfully deploy this innovative harm reduction strategy.

Less is More: Selective reduction of CT data for self-supervised pre-training of deep learning models with contrastive learning improves downstream classification performance

Background:Self-supervised pre-training of deep learning models with contrastive learning is a widely used technique in image analysis. Current findings indicate a strong potential for contrastive pre-training on medical images. However, further research is necessary to incorporate the particular characteristics of these images. Method:We hypothesize that the similarity of medical images hinders the success of contrastive learning in the medical imaging domain. To this end, we investigate different strategies based on deep embedding, information theory, and hashing in order to identify and reduce redundancy in medical pre-training datasets. The effect of these different reduction strategies on contrastive learning is evaluated on two pre-training datasets and several downstream classification tasks. Results:In all of our experiments, dataset reduction leads to a considerable performance gain in downstream tasks, e.g., an AUC score improvement from 0.78 to 0.83 for the COVID CT Classification Grand Challenge, 0.97 to 0.98 for the OrganSMNIST Classification Challenge and 0.73 to 0.83 for a brain hemorrhage classification task. Furthermore, pre-training is up to nine times faster due to the dataset reduction. Conclusions:In conclusion, the proposed approach highlights the importance of dataset quality and provides a transferable approach to improve contrastive pre-training for classification downstream tasks on medical images.

Preparation of a branched hierarchical Co3O4@Fe2O3 core–shell structure with high-density catalytic sites for efficient catalytic conversion of nitrate in wastewater to ammonia

This work employs a high-efficiency, low cost and environmentally friendly electrochemical nitrate reduction (NO3RR) strategy to realize the highly selective conversion of a typical environmental pollutant-nitrate to an extremely important chemical product-ammonia. To ensure high ammonia selectivity and Faradaic efficiency, a branched hierarchical Co3O4@Fe2O3 core–shell structure was synthesized on carbon cloth (CC) using a simple two-step hydrothermal method. After material characterization and parameter optimization, a nitrate conversion rate of 88.4 %, ammonia selectivity of 89.4 %, Faradaic efficiency of 87.2 % and NH3-N yield rate of 3810 μg h−1 cm−2 were obtained at Co3O4@Fe2O3|CC, which also displayed durability by retaining a high Faradaic efficiency of 79.3 % after six consecutive NO3RR cycles. Investigation of the mechanism reveals that active atomic *H plays a key role in the NO3RR. The excellent NO3RR performance of Co3O4@Fe2O3|CC is attributed to its branched hierarchical core–shell structure with large electrochemical surface area and fully exposed catalytic sites. In addition, both experimental and density functional theory (DFT) calculations indicate that the Co3O4@Fe2O3 core–shell structure is superior to Co3O4|CC and Fe2O3|CC in catalyzing NO3RR due to the synergistic effect between Co3O4 and Fe2O3. This synergistic effect can promote the adsorption of NO3–, release of NH3 and inhibition of hydrogen evolution, ensuring the highly selective and efficient conversion of NO3– to NH3. This work demonstrates that the morphology of an electrocatalyst can significantly affect its performance for the NO3RR, and has potential for practical application purposes.

Granular insights into occupant behaviours and CO2 emissions in the UK

Addressing global climate change necessitates a deep understanding of the sources of CO2 emissions, particularly at the individual level. While existing research has explored in depth the behavioural awareness of individual/household carbon emissions and its overall impacts, there remain significant research gaps in the understanding of how behavioural adjustments, influenced by individual factors, can be made to achieve carbon emission reductions under the current market mechanisms. This study aims to fill this gap by providing a detailed analysis of the carbon emissions associated with various activities of residents. Utilising the UK Time Use Survey, we applied path analysis and t-statistics to dissect how distinct occupant behaviours and their characteristics impact CO2 emissions. Our findings reveal age is a predominant driving factor in employment, studying, and media consumption, while gender significantly impacts household and care-related activities, and income levels influence emissions from hobbies and transportation. These insights highlight the importance of developing carbon reduction strategies that are developed on an individual behavioural basis to reach behavioural adjustments. Our analysis provides quartile results for different behaviours, aiding policymakers in devising carbon reduction strategies tailored to occupants' emissions profiles. Meanwhile, using scenario analysis, the policy has a carbon reduction potential ranging from 29.59% to 75.36%. Overall, our study offers empirical data and granular insights that can inform targeted interventions and policy formulations aimed at promoting carbon neutrality by focusing on the specific behaviours of individual occupants.

Reducing the cost of home energy upgrades in the US: An industry survey

Decarbonizing the US residential building stock requires a substantial acceleration in home energy upgrades. Numerous barriers exist to accelerating adoption of efficient and electric building technologies, but foremost among these is high upfront costs. This study uses an industry survey delivered to a sample of home energy professionals to examine promising cost reduction strategies across a range of project types, including HVAC, water heating, and envelope/insulation projects. The survey included quantitative and qualitative questions to collect evidence on the estimated cost reduction potential of these strategies and their likelihood of use in the construction industry. The 167 survey respondents included contractors, energy consultants, architects, manufacturers, and others with experience in delivering energy upgrades in single-family and multifamily buildings in the US. Results show that significant cost reductions are achievable by minimizing additional infrastructure costs (such as replacing electric panels), streamlining project planning/management, and deploying innovations that simplify installation. We find that for a typical deep retrofit project, including heat pumps for space and water heating in addition to envelope upgrades, the strategies could result in a total installed cost reduction of nearly 50 %, dramatically improving the customer economics of such a project. This research makes a novel contribution to the literature on strategies to reduce the costs of residential retrofits. We discuss how our study's insights on the highest-value cost reduction strategies for home energy upgrades can further accelerate their uptake in the US housing stock.

Application of propionate-producing bacterial consortium in ruminal methanogenesis inhibited environment with bromoethanesulfonate as a methanogen direct inhibitor.

Methane production in ruminants is primarily due to the conversion of metabolic hydrogen (H2), produced during anaerobic microbial fermentation, into methane by ruminal methanogens. While this process plays a crucial role in efficiently disposes of H2, it also contributes to environmental pollution and eliminating methane production in the rumen has proven to be challenging. This study investigates the use of probiotics, specifically propionate-producing bacteria, to redirect accumulated H2 in a methane-mitigated environment. For this objective, we supplemented experimental groups with Lactiplantibacillus plantarum and Megasphaera elsdenii for the reinforced acrylate pathway (RA) and Selenomonas ruminantium and Acidipropionibacterium thoenii for the reinforced succinate pathway (RS), as well as a consortium of all four strains (CB), with the total microbial concentration at 1.0 × 1010 cells/mL. To create a methane-mitigated environment, 2-bromoethanesulfonate (BES) was added to all experimental groups at a dose of 15 mg/0.5 g of feed. BES reduced methane production by 85% in vitro, and the addition of propionate-producing bacteria with BES further decreased methane emission by up to 94% compared with the control (CON) group. Although BES did not affect the alpha diversity of the ruminal bacteriome, it reduced total volatile fatty acid production and altered beta diversity of ruminal bacteriota, indicating microbial metabolic adaptations to H2 accumulation. Despite using different bacterial strains targeting divergent metabolic pathways (RA and RS), a decrease in the dominance of the [Eubacterium] ruminantium group suggesting that both approaches may have a similar modulatory effect. An increase in the relative abundance of Succiniclasticum in the CB group suggests that propionate metabolism is enhanced by the addition of a propionate-producing bacterial consortium. These findings recommend using a consortium of propionate-producing bacteria to manage H2 accumulation by altering the rumen bacteriome, thus mitigating the negative effects of methane reduction strategies.

Stochastic Differential Games of Carbon Emission Reduction in the Four-Tier Supply Chain System Based on Reference Low-Carbon Level

This paper takes corporate social responsibility goodwill and consumers’ reference low-carbon level as endogenous variables of joint carbon emission reduction in the “supplier–manufacturer–retailer–consumer” supply chain system. The joint carbon emission reduction strategies of this four-tier system are analyzed from a dynamic perspective by considering random factors that affect the endogenous variables. Three stochastic differential games are proposed to examine the mechanism between each player, namely the cooperative model, Nash non-cooperative model, and Stackelberg master–slave model. Compared to the Nash non-cooperative game, the manufacturer/supplier-led Stackelberg master–slave game leads to Pareto improvement in the profits of the entire supply chain system and each player. The cooperative game demonstrates the highest expected emission reduction and corporate social responsibility goodwill, but also the highest variance. More importantly, the reference low-carbon level embraces consumers’ subjective initiative in the dynamic of carbon emission reduction. This level is an internal benchmark used to compare against the observed low-carbon level. This paper provides a theoretical foundation for strategic decision-making in emission reduction, contributing to sustainable development. By addressing environmental, economic, and social sustainability, it promotes climate action through carbon reduction strategies and offers policy recommendations aligned with the Sustainable Development Goals.

First Law a gift to healing and transforming climate and just us!

PurposeThese words of introduction locate me on my tribal ancestral lands, and centres me as belonging to the Martuwarra, Fitzroy River in the Kimberley region of Western Australia. My family and community’s inter-generational lived experiences of colonisation are grounded in the characteristics and learnings of “conflict, manipulation, dived and rule” as invasive unjust strategies of oppression and anti-dialogic action. These characteristics of oppression reflect invasive and unjust developments, colonialism continues to impact on our daily lives and threaten our cultural heritage, lifeways and livelihoods (Freire, 2005).Design/methodology/approachI understand the Net Zero: Heritage for Climate Action is a first of its kind, a capacity development project that aims to use Indigenous knowledge to develop integrated strategies for disaster risk reduction, climate action and peacebuilding (Jarillo and Crivelli, 2024). Importantly, one of the aims of the Net Zero Project is to enhance risk reduction and coping capacities of vulnerable heritage communities. In this way, my video story speaking directly to the International Union for the Conservation of Nature (IUCN) highlights the interconnected issue of heritage safeguard, upholding cultural rights and sustainable development of our people who are vulnerable cultural bearers, importantly, how we are working to effect change locally, while strengthening efforts globally, as we see ourselves as planetary citizens with a duty of care to Mother Earth and humanity (Redvers et al., 2020).FindingsThe opportunity for freedom is being created through the growing coalitions of hope (Poelina, 2020). Organisations with a regenerative focus are connecting, networking, collectively thinking and transforming our world by being brave and challenging legal systems to recognise “rivers” as the lifeblood of our planet and our survival co-dependent on “a declaration of peace with Indigenous Australians with natures laws and first law” (RiverOfLife et al., 2024). Together we are decolonising our thinking; uniting and bringing together a pluriverse of ideas and actions to right size our planet and give humanity and Mother Earth a climate chance (RiverOfLife et al., 2024).Research limitations/implicationsThe final question, I ask my country and the world to sustain my culture, my home, my lifeways and my livelihood “can we achieve peace, harmony and balance”? Can we shift from business as usual, to the new economies, through intentional communities, through bicultural and bioregional planning and development? If the answer is yes, then there is hope for humanity, and the young ones yet to be born. Let us adopt the values, ethics and virtues found in First Law as a gift to healing our lands, our people and climate.Practical implicationsIt is clear from the voices of Yi-Martuwarra people, “If [our] River Dies, We Die” (Moore et al., 2023). When we stand united, we hold the dreaming time, from past, present and future, and we sing together a new “Martuwarra River Time” song. Through this moral and ethical partnership of hope the Net Zero Project Heritage for Climate Action ignites the opportunity to transform climate change, climate chaos and provide the climate chance through just us!Social implicationsYi-Martuwarra people highlight the need for dialogue, unity, cooperation and multiple forms of evidence, to understand the cumulative impacts of development. It is clear from the voices of Yi-Martuwarra people, “If [our] River Dies, We Die” (Moore et al., 2023). When we stand united, we hold the dreaming time, from past, present, and future, and we sing together a new “Martuwarra River Time” song. Through this moral and ethical partnership of hope the Net Zero Project Heritage for Climate Action ignites the opportunity to transform climate change, climate chaos and provide the climate chance through just us!Originality/valueAs the impacts of climate change continue to intensify, it is imperative to centre Indigenous well-being in adaptation efforts by enabling bottom-up approaches via community-led solutions, promoting land rights, protecting traditional heritage and cultural practices and cultivating social connections. Given the increasing recognition of well-being as a fundamental marker of successful adaptation, it should be central to climate change research and policymaking, but for this to be of benefit to Indigenous Peoples and local communities context-specific understandings of health and well-being are necessary (Jarillo and Crivelli, 2024).

LEAP! Rx: A randomized trial of a pragmatic approach to lifestyle medicine.

Clinicians lack the tools to incorporate physical activity into clinical care for Alzheimer's disease prevention. We tested a 52-week exercise and health education program (Lifestyle Empowerment for Alzheimer's Prevention [LEAP! Rx]) that integrates clinician referrals and community-based fitness resources. We randomized 219 participants to the LEAP! Rx (ie, exercise and monthly brain health education) or a standard-of-care control group and tested the effects on cardiorespiratory fitness, insulin resistance, body composition, lipids, and cognitive performance. Physicians were able to connect their patients to a community lifestyle intervention. The intervention group increased in cardiorespiratory fitness at 12 and 52 weeks (p=0.005). We observed no effects on secondary measures. Participants meeting 80% of weekly goals (150 min, moderate to vigorous activity) saw greater fitness improvements than those with less than 80% (p<0.001). These results hold promise for broad implementation of exercise interventions into larger healthcare systems and have implications for improved research recruitment strategies. NCT No. NCT03253341. Our community-based exercise program increased cardiorespiratory fitness. Our digital physician referral method increased the diversity of the participant sample. Our findings have implications for personalized dementia risk reduction strategies.

Characteristics of Ozone Photochemical Reaction and Emission Reduction Strategies in Summer and Autumn in Shangqiu

Recently, ozone （O3） pollution in Shangqiu has become increasingly prominent, especially in summer and autumn, crucially affecting the local environmental air quality. Based on the monitoring data of O3 pollution days from the Environmental Monitoring Station in June and September 2022 （representing summer and autumn） in Shangqiu, an observation-based model （OBM） was used to study the causes and photochemical reaction characteristics of O3 pollution in the city and precursor emission reduction strategies were studied. The observation results indicated that during summer in Shangqiu, the ρ（O3） and O3 daily maximum 8 h moving concentrations [ρ（MDA8-O3）] were 149.7 μg·m-3 and 195.4 μg·m-3, whereas in autumn, ρ（O3） and ρ（MDA8-O3） were 119.8 μg·m-3 and 173.9 μg·m-3, respectively； the O3 concentration in summer was significantly higher than that in autumn. Ozone sensitivity research showed that the generation of O3 in summer and autumn in Shangqiu was controlled by volatile organic compounds （VOCs）. Among them, oxygen-containing volatile organic compounds （OVOCs）, aromatic hydrocarbons, and alkenes contributed the most to the ozone generation potential （OFP） and ·OH reactivity （L·OH）, and the control must have been strengthened. The OBM simulation results indicated that the maximum O3 generation rates in summer and autumn were 23.0×10-9 h-1 and 13.6×10-9 h-1, with maximum net generation rates of 17.4×10-9 h-1 and 10.4×10-9 h-1 and the maximum and maximum net generation rates of O3 in summer were 1.68 times higher than those in autumn, indicating that the photochemical reactions in summer were significantly stronger than those in autumn. Compared with that in summer, the generation of O3 in autumn was greatly influenced by regional inputs from other regions or cities, with a maximum input of 14.2×10-9 h-1. The prevention and control of O3 pollution in the summer and autumn seasons in Shangqiu should mainly focus on controlling VOCs. The reduction ratio of VOCs/nitrogen oxides （NOx） in autumn should be greater than that in summer and the reduction ratios of 3∶1 in summer and 4∶1 in autumn could be adopted for control.

Perioperative anaphylaxis: Management and risk reduction strategies in 2024

Perioperative anaphylaxis: Management and risk reduction strategies in 2024

Estimation of carbon emissions in various clustered regions of China based on OCO-2 satellite XCO2 data and random forest modelling

Atmospheric carbon dioxide (CO2) stands as one of the most important greenhouse gasses, with steadily increasing concentrations attributable to human activities. In the pursuit of reaching peak carbon and carbon neutrality goals, it is essential to quantify carbon emissions and evaluate carbon reduction strategies. To establish a high-precision observation with full time series and spatial coverage, a spatio-temporal interpolation method was developed to obtain XCO2 data over mainland China at a resolution of 0.5° × 0.5° for the years 2015–2021. An east-west gradient, higher levels in the east and lower levels in the west, was observed, exhibiting a seasonal pattern of elevation in spring and reduction in summer. Subsequently, the research area is classified into seven clusters based on time-series XCO2 anomalies (ΔXCO2) and ODIAC (Open Source Data Inventory of Anthropogenic Carbon Dioxide) carbon emission data. This classification aims to emphasize the differentiation of spatial heterogeneity in carbon emissions and the results highlight that regions with high ΔXCO2 reflect higher carbon emission. Finally, the carbon emissions of each cluster were estimated by using a random forest model individually yielding an R2 of approximately 0.6. For assessing the variables influencing carbon emission predictions, the importance of each variable was calculated. Specifically, NightTime Lighting data (NTL), representing human production activities, emerged as a crucial variable influencing carbon emission predictions in most clusters. In comparison, Gross Primary Productivity (GPP) is considered a more critical variable in Southwest China (SWC), primarily owing to the intricate vegetation carbon sink system in this region. Temperature (T) emerges as a key variable influencing the estimation of carbon emissions in certain developed cities in Eastern China (EC), driven by the urban heat island effect which amplifies energy consumption, modifies land use, and impacts urban systems, influencing the spatial patterns of carbon emissions. Carbon emissions in different characteristic regions was quantified by establishing machine learning models with remote sensing data, which can provide new insights and support for refined carbon monitoring and management strategy.

Legal Barriers in Sustainable Agriculture: Valorization of Agri-Food Waste and Pesticide Use Reduction

The transition to sustainability in agriculture faces significant challenges, especially to balance environmental goals with the practical demands of food production. This paper examines two different case studies that reveal the complexities of agricultural regulation. The first case focuses on the valorization of agri-food residual biomasses, highlighting the potential to transform food waste into valuable bioproducts such as bioenergy and biofertilizers. Despite the clear environmental and economic benefits, the absence of specific European regulations hinders the widespread adoption of these practices. Without clear rules for achieving “end-of-waste” status, the development and marketing of bio-based products remain restricted. The second case study examines the European Union’s unsuccessful effort to implement the Sustainable Use of Pesticides Regulation (SUR), which aimed to reduce pesticide use by 50% by 2030. Although the regulation sought to align agricultural practices with the EU’s Green Deal, it triggered widespread protests from farmers concerned about the potential economic losses and decreased productivity. These two cases, one showing under-regulation and the other over-regulation, highlight the need for balanced and practical regulatory frameworks that promote sustainability without imposing unrealistic demands on stakeholders. This paper ends with recommendations to harmonize regulations across Europe, ensuring that both innovation in agricultural waste management and practical pesticide reduction strategies are implemented in a way that supports farmers and producers, minimizing economic disruptions and encouraging sustainable agricultural practices.

"I drink less and that's no small matter": a qualitative descriptive study of a managed alcohol program evaluation in Barcelona.

Background: The concurrence of homelessness and alcohol use disorder (AUD) has negative consequences in affected individuals. Managed alcohol programs (MAPs), a harm reduction strategy based on providing regular doses of alcohol to individuals with AUD, have emerged as a potential solution to reduce alcohol-related harms.Objectives: This study examined the impact of a MAP implemented in Barcelona on patterns of alcohol and other psychoactive substance use, health, and quality of life among people who use drugs and were experiencing homelessness. The research also incorporated a gender perspective and focused on individuals who had accessed a residential center.Methods: A descriptive qualitative design was used, employing semi-structured interviews with eight participants who were enrolled in the MAP (three women, five men) and four program professionals. Thematic analysis was used to analyze the resulting data.Results: The domains guiding the study appeared as outcome themes: patterns of use of alcohol and other substances, health, quality of life and impact on female-identified participants. Participants reported improved health due to reduced consumption of alcohol and other substances, better anxiety management, and reconnection to health services. The participants reported enhanced quality of life, including feeling safer, and better use of time, which had been spent on meeting their basic needs. Women reported that a key benefit of the program was living in a sexism-free environment.Conclusion: These results appear to demonstrate that harm reduction strategies prioritizing basic needs and adopting a gender-sensitive perspective can positively impact the health and quality of life of people experiencing homelessness with AUD.