Saline soils with complex ecosystems limit biotic activities, and the reclamation of these soils can be favorable for soil health. A pot experiment was conducted in a completely randomized design with three replications to reclaim artificially induced salinity-related attributes in soil (7.0 dS m−1) using various cyanobacteria strains. For this purpose, six treatments were used, control, Oscillatory-MMF-1 (Oscillatoria princeps), Leptolyngbaya-MMF-2 (Lyngbya mucicola), Leptolyngbaya-MMF-3 (Lyngbya Phormidium), Gloeobacter-MMF-4 (Gloeocapsa) and Microcoleus-MMF-5 (Cryophilus). The salinity-induced soil was treated with the appropriate treatments before the transplantation of rice seedlings to each pot. The rice crop was grown for 100 days and monitored for growth attributes. Similarly, the soil was monitored for physicochemical properties. The experimental results revealed a significant reduction in soil pH from 8.32 to 7.20, EC from 7 to 5.2 dS m−1, Na+ from 2552 to 1146 mg kg−1, soil bulk density from 1.37 to 1.31 g cm−3 by the cyanobacterial strain MMF-4 Gloeobacter (Gloeocapsa), showing 13.5%, 25.7%, 55% and 4.38% decrease respectively. Whereas the cyanobacterial strain (Gloeobacter) significantly enhanced the concentration level of Ca++ (944 mg kg−1), Mg++ (358 mg kg−1) and increased the porosity up to 50.69% and saturation percentage (35.50) in the induced saline soils. It can be concluded from the findings that all the strains of cyanobacteria reclaimed soil salinity by reducing soil EC, pH, SAR, and soil bulk density and increased Ca++, Mg++, porosity, and saturation percentage (SP) in the saline soil. However, the best performance was recorded for MMF-4 (Gloeobacter) and MMF-5 (Microcoleus) strains and recommended for further research.