Reduce Joint Pain Research Articles

Pengaruh Serai (Cymbopogon Citratus) Terhadap Penurunan Nyeri Gout Athritis pada Masyarakat di Kelurahan Winenet Satu Kota Bitung

People with gout arthritis complain of pain in the joints, toes, hands, knees and have never used lemongrass water to reduce joint pain and choose analgesic drugs as pain relief. Lemongrass plant contains essential oil that has chemical properties and pharmacological effects, namely a spicy and warm taste as an anti- inflammatory and relieving analgesic pain.. The purpose of this research was to find out the effect of lemongrass (cymbopogon citratus) on the reduction of gout arthritis pain in The Community In The 1st Winenet Village, Bitung. This research used a pre experimental method with one group pretest-posttest design. The population were residents who suffered from gout arthritis and who experienced joint pain. Sampling using a purposive sampling technique with the number of samples were 12 respondents using the Lamesho formula. The instruments used in this research were observation sheets and pain intensity scale measurement sheets using the Numeric Rating Scale (NRS). The collected data was processed by running the computer program be analyzed by a Wilcoxon Signed Rank test with the significance level α = 0,05.The results of this research indicated that there are differences in pain intensity before and after giving lemongrass, with a ρ value (0,001) < (0,05), meaning that there is an effect of giving lemongrass on reducing gout arthritis pain.The conclusion of this research is that lemongrass can be used as a non- pharmacological therapy to reduce pain in gout arthritis. It is expected that the result of this research will be useful in reducing pain in patients with gout arthritis and can be used as an additional reference for further research.
 

Material full of promises: Hg1-xCdXTe - mercury cadmium telluride

In recent decades’ doctors and scientists have intensively researched the effect of infrared applications. The rays of infrared devices penetrate the body to a depth of about 5 cm and provide a pleasant warmth, stimulating blood circulation and reducing joint pain. Long-wave infrared light exerts a beneficial effect on nerve cells. These nerve cells are responsible for transmitting the sensation of pain to the brain. Infrared light treatment increases the release of endogenous analgesic substances from the brain and adrenal glands, such as enkephalins and endorphins. The infrared range of the electromagnetic spectrum extends from about 0.75 μm to 1000 μm. The article presents a review of HgCdTe infrared detectors, which have been intensively developed in the last forty years since the first synthesis of this compound semiconductor in 1958.

Efficacy and safety of Tuina (Chinese Therapeutic Massage) for knee osteoarthritis: A randomized, controlled, and crossover design clinical trial.

Knee osteoarthritis (KOA) is a highly prevalent joint disease among the middle-aged and elderly population that can lead to pain, functional impairment, decreased quality of life, and a large number of medical expenses. Physical therapy is one of the main treatment methods for KOA. In China, Tuina has been widely used in the treatment of KOA, but up to now, there is no high-quality medical evidence to support its effectiveness and safety. The purpose of this study was to objectively evaluate the efficacy and safety of Tuina in the treatment of KOA. A crossover design clinical trial was performed on 96 patients. The test group and the control group in the trial were allocated randomly in a ratio of 1:1. The test group received Tuina treatment for 4 weeks first and then received health education intervention for another 4 weeks. The control group received health education intervention for 4 weeks first and then received Tuina treatment for another 4 weeks. The Western Ontario and McMaster Universities Arthritis Index (WOMAC) total score was chosen as the primary outcome. The WOMAC pain score, WOMAC stiffness, WOMAC daily activity score, and visual analog scale (VAS) score were the secondary outcomes. Adverse events during the intervention were collected in both groups. Compared with the baseline, the WOMAC total score, WOMAC pain score, WOMAC stiffness, WOMAC daily activity, and VAS score of patients in both groups were improved significantly at weeks 4 and 8 (p < 0.001). All patients who received Tuina treatment were significantly superior to those who received health education intervention in the WOMAC total score (194.96, 95% CI = 164.94-224.97, P < 0.001), WOMAC pain score (45.96, 95% CI = 35.82-56.09, P < 0.001), WOMAC stiffness (31.42, 95% CI = 26.37-36.46, P < 0.001), WOMAC daily activity (117.58, 95% CI = 97.56-137.61, P < 0.001), and VAS score (1.07, 95% CI = 0.83-1.32, P < 0.001). Both groups had no serious adverse events during the treatment. This trial demonstrated that Tuina can reduce joint pain in patients with KOA and improve the physical functions of the knee joint effectively and safely. This trial was registered in the Chinese Clinical Trial Registry (No. ChiCTR-TTRCC-13003157). http://www.chictr.org.cn/showproj.aspx?proj=6402.

Development of a mobile application to monitor the effectiveness of a hydrolyzed cartilage matrix supplement on joint discomfort: a real-life study.

Joint discomfort is a widespread and growing problem in active adults. The rising interest in preventative nutrition has increased the demand for supplements reducing joint discomfort. Protocols assessing the effect of a nutritional intervention on health commonly involve a series of face-to-face meetings between participants and study staff that can weigh on resources, participant availabilities and even increase drop-out rates. Digital tools are increasingly added to protocols to facilitate study conduct but fully digitally run studies are still scarce. With the increasing interest in real-life studies, the development of health applications for mobile devices to monitor study outcomes could be of great importance. The purpose of the current real-life study was to develop a specific mobile application, Ingredients for LifeTM, to conduct a 100% digital study testing the effectiveness of a hydrolyzed cartilage matrix (HCM) supplement on joint discomfort in a heterogeneous group of healthy, active consumers. The 'Ingredients for LifeTM ' mobile app using Visual Analog Scale (VAS) was specifically developed to monitor the variation in joint pain after exercise by the study participants. A total of 201 healthy and physically active, adult women and men (18 to 72 years old) with joint pain completed the study over a period of 16 weeks. Participants were randomly allocated to the study groups and did not receive any dietary or lifestyle advice. Each participant indicated one area of joint pain and logged the type and duration of their weekly activities. They received blinded study supplements and took a daily regimen of 1 g of hydrolyzed cartilage matrix (HCM-G) or 1g of maltodextrin (placebo group; P-G) for 12 weeks while weekly logging joint pain scores in the app. This was followed by a 4-week wash out period during which participants continued reporting their joint pain scores (until the end of week 16). Joint pain was reduced within 3 weeks of taking a low dosage of HCM (1g/day), regardless of gender, age group and activity intensity when compared to the placebo-group. After stopping supplementation, joint pain scores gradually increased but still remained significantly lower than placebo after 4 weeks of washout. The low dropout rate (< 6% of participants, mainly in the P-G) demonstrates the digital study was well received by the study population. The digital tool allowed to measure a heterogeneous group of active adults in a real-life setting (without any lifestyle intervention), thus promoting inclusivity and diversity. With low dropout rates, it demonstrates that mobile applications can generate qualitative, quantifiable, real-world data showcasing supplement effectiveness. The study confirmed that the oral intake of a low dose (1g/day) of HCM led to a significant reduction of joint pain from 3 weeks after starting supplementation.

Nursing Intervention of Red Ginger Warm Compress To Reduce Pain Levels In The Elderly

Background: Gout arthritis or often known by the public as uric acid is a degenerative problem that attacks the joints and is most often found in society, especially in the elderly. Often found complaints of joint pain in gout sufferers, the way to deal with pain is by warm compresses of red ginger. The goal is to reduce pain and improve blood circulation. Methods: Case study by providing nursing care to Mrs.S who is 60 years old with complaints of joint pain. Results: Based on a case study conducted by the author for 7 days, joint pain due to increased uric acid was reduced from pain scale 5 to scale 1. Conclusion: Giving red ginger warm compresses regularly can inhibit prostaglandin synthesis so as to reduce joint pain or tension muscle because it contains olerasin, namely gingerol, zingeron and shogaol.

Pentosan Polysulfate Affords Pleotropic Protection to Multiple Cells and Tissues.

Pentosan polysulfate (PPS), a small semi-synthetic highly sulfated heparan sulfate (HS)-like molecule, shares many of the interactive properties of HS. The aim of this review was to outline the potential of PPS as an interventional therapeutic protective agent in physiological processes affecting pathological tissues. PPS is a multifunctional molecule with diverse therapeutic actions against many disease processes. PPS has been used for decades in the treatment of interstitial cystitis and painful bowel disease, it has tissue-protective properties as a protease inhibitor in cartilage, tendon and IVD, and it has been used as a cell-directive component in bioscaffolds in tissue engineering applications. PPS regulates complement activation, coagulation, fibrinolysis and thrombocytopenia, and it promotes the synthesis of hyaluronan. Nerve growth factor production in osteocytes is inhibited by PPS, reducing bone pain in osteoarthritis and rheumatoid arthritis (OA/RA). PPS also removes fatty compounds from lipid-engorged subchondral blood vessels in OA/RA cartilage, reducing joint pain. PPS regulates cytokine and inflammatory mediator production and is also an anti-tumor agent that promotes the proliferation and differentiation of mesenchymal stem cells and the development of progenitor cell lineages that have proven to be useful in strategies designed to effect repair of the degenerate intervertebral disc (IVD) and OA cartilage. PPS stimulates proteoglycan synthesis by chondrocytes in the presence or absence of interleukin (IL)-1, and stimulates hyaluronan production by synoviocytes. PPS is thus a multifunctional tissue-protective molecule of potential therapeutic application for a diverse range of disease processes.

Effects of Physical Therapy on Joint Pain, Joint Range of Motion, Joint Health, Strength, and Mobility in Patients With Hemophilia: A Systematic Review and Meta-analysis.

This study investigated the effects of physical therapy, including exercise, manual therapy, and physical agent modality, on joints, muscle strength, and mobility of patients with hemophilia. PubMed, Embase, MEDLINE, Cochrane Central Register of Controlled Trials, Web of Science, and Scopus were searched from inception to September 10, 2022. Randomized controlled trials comparing pain, range of motion, and health of joints, as well as muscle strength and mobility (timed up and go test) between physical therapy and control groups were included. Fifteen randomized controlled trials with 595 male patients with hemophilia were included. In comparisons between physical therapy and control groups, physical therapy significantly reduced joint pain (standardized mean difference = -0.87; 95% confidence interval, -1.14 to -0.60), increased joint range of motion (standardized mean difference = 0.24; 95% confidence interval, 0.14-0.35), enhanced joint health (standardized mean difference = -1.08; 95% confidence interval, -1.38 to -0.78), improved muscle strength (standardized mean difference = 1.42; 95% confidence interval, 1.16-1.69), and timed up and go test performance (standardized mean difference = -1.25; 95% confidence interval, -1.89 to -0.60). The comparisons demonstrate moderate to high evidentiary quality grades. Physical therapy is effective in reducing pain, increasing joint range of motion, enhancing joint health, as well as improving muscle strength and mobility in patients with hemophilia. Complete the self-assessment activity and evaluation online at http://www.physiatry.org/JournalCME. Upon completion of this article, the reader should be able to: (1) Recognize the overall effectiveness of physical therapy for patients with hemophilia; (2) Determine how therapeutic exercise can help improve various outcomes of major joints in these patients; and (3) Appraise that physical therapy is safe and can be implemented in clinical practice for these patients. Advanced. The Association of Academic Physiatrists is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.The Association of Academic Physiatrists designates this Journal-based CME activity for a maximum of 1.0 AMA PRA Category 1 Credit(s) ™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Surgical accuracy and clinical outcomes of image-free robotic-assisted total knee arthroplasty.

The development of total knee arthroplasty (TKA) for knee osteoarthritis (OA) has a good reputation for its effectiveness in reducing joint pain and improving range of motion. We aimed to review our early results using the image-free robotic-assisted technology in knee arthroplasty. A total of 71 patients suffering from end-stage OA knee receiving TKA operated by robotic-assisted surgery between the years 2018 and mid-2021 were recruited. Clinical and radiological outcomes were compared with age and sex-matched control group (conventional TKA). The radiological outcome showed significantly more postoperative lower limb alignment outliers in conventional side than robotic-assisted sides. Postoperative knee scores were similar among both groups. Robotic-assisted TKA required a longer implantation time but a shorter hospital stay. Robotic-assisted TKA achieved a lower rate of mechanical axis Outlier in the coronal and sagittal plane with a shorter hospital stay. Yet both methods achieve a similar functional outcome.

Efficacy of topical oleoresin of Pistacia atlantica L. subspecies kurdica for symptomatic relief of knee osteoarthritis: A randomized double-blinded controlled trial

IntroductionData suggest that topical use of the oleoresin of Pistacia atlantica subspecies could relieve joint pain. Therefore, the efficacy and safety of topical cream of oleoresin of P. atlantica subspecies kurdica (OPAK) were evaluated for the symptomatic treatment of the Kellgren-Lawrence grade 1 or 2 knee osteoarthritis. MethodsFifty patients applied topical OPAK and 50 other patients applied placebo on the knees every 8 h for 1 month. Outcome measures were WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index) pain, stiffness, function and total scores; 12-Item Short-Form Health Survey (SF-12) and Health Assessment Questionnaire-Disability Index (HAQ-DI) scores; number of 500 mg acetaminophen tablets taken per day during the trial; and hematological and kidney and liver function tests. ResultsDecrease of pain and stiffness and improvement of function in the OPAK group were statistically more than the placebo group (p < 0.001, p = 0.006, p < 0.001 respectively). The OPAK group used significantly fewer acetaminophen tablets during the trial compared with the placebo group (p < 0.001). The increase of SF-12 score and decrease of HAQ-DI score in the OPAK group were significantly more than in the placebo group (p < 0.001 for both parameters). OPAK had no significant effects on the other parameters compared with the placebo and no local and systemic side effects were observed in the patients. ConclusionsTopical OPAK is safe and reduces joint pain, stiffness and dysfunction and analgesic dose, and improves quality of life in the knee osteoarthritis patients.

The Role of Vitamin D in the Development and Progression of Osteoarthritis

"Low levels of vitamin D in patients with osteoarthritis (ΟΑ) rather adversely affect the structure and function of articular cartilage. Low levels of vitamin D are also associated with joint pain, limited physical activity, quality of life, as well as decreased muscle strength, primarily in the lower extremities with adverse OA progression. A high percentage of low vitamin D levels was found in patients with OA and joint arthroplasty as well as a less satisfactory postoperative follow-up in patients with low vitamin D levels. The administration of vitamin D supplementation in patients with knee osteoarthritis has been associated with improved articular cartilage architecture, and reduced joint pain, combined with improved functionality and quality of life in patients with OA. "

Exercise &amp; Sports Science Australia (ESSA) updated Position Statement on exercise and physical activity for people with hip/knee osteoarthritis

This Position Statement is an update to the existing statement. It is intended for all health practitioners who manage people with hip/knee osteoarthritis. It synthesises the most recent evidence (with a focus on clinical guidelines and systematic reviews) for exercise in people with hip/knee osteoarthritis, and provides guidance to practitioners about how best to implement exercise in clinical practice. Clinical practice guidelines for hip/knee osteoarthritis advocate physical activity and exercise as fundamental core components of evidence-based management. Research evidence indicates that exercise can reduce joint pain, increase physical function, and improve quality of life in hip/knee osteoarthritis, and that a range of exercise types (both supervised and unsupervised) may be beneficial. Exercise dosage should be guided by the principles of the American College of Sports Medicine. As people with osteoarthritis experience many barriers to exercise, practitioners should take an active role in monitoring and promoting adherence to exercise in order to optimise therapeutic benefits.

Targeting Vascular Endothelial Growth Factor Receptors as a Therapeutic Strategy for Osteoarthritis and Associated Pain.

Pain is the major reason that patients suffering from osteoarthritis (OA) seek medical care. We found that vascular endothelial growth factors (VEGFs) mediate signaling in OA pain pathways. To determine the specific contributions of VEGFs and their receptors (VEGFRs) to joint pathology and pain transmission during OA progression, we studied intra-articular (IA) injections of VEGF ligands into murine knee joints. Only VEGF ligands specific for the activation of VEGFR1, but not VEGFR2, induced allodynia within 30 min. Interventions in OA by inhibitors of VEGFRs were done in vivo using a preclinical murine OA model by IA injections of selective inhibitors of VEGFR1/VEGFR2 kinase (pazopanib) or VEGFR2 kinase (vandetanib). OA phenotypes were evaluated using pain-associated murine behavioral tests and histopathologic analyses. Alterations in VEGF/VEGFR signaling by drugs were determined in knee joints, dorsal root ganglia, and spinal cord by immunofluorescence microscopy. Pazopanib immediately relieved OA pain by interfering with pain transmission pathways. Pain reduction by vandetanib was mainly due to the inhibition of cartilage degeneration by suppressing VEGFR2 expression. In conclusion, IA administration of pazopanib, which simultaneously inhibits VEGFR1 and VEGFR2, can be developed as an ideal OA disease-modifying drug that rapidly reduces joint pain and simultaneously inhibits cartilage degeneration.

PENGARUH KOMPRES HANGAT JAHE MERAH TERHADAP SKALA NYERI LANSIA OSTEOARTHRITIS DI BALAI SOSIAL LANJUT USIA MANDALIKA MATARAM

Osteoarthritis is a disorder deseaseof the joint that cause the decrease of join motion. Pain is amajor problem in osteoarthritis patients, so the management of this disease focuses on efforts to resolve or recover from the pain. Giving a red ginger compress is an alternative to reduce joint pain in elderly who suspect of osteoarthritis. This research was conducted at BalaiSoaialLanjutUsia( BSLU )MandalikaMataram. The research design used in this research was experimental observational with one group pretest-posttest. The sampling technique used purposive sampling with a sample quantity of 14 respondents and the data collection tool in this study was the observation sheet.Data were analyzed by univariate and bivariate. The Wilcoxon test results obtained a value of 0.001 (p value &lt;0.05). It can be concluded that the warm red ginger compress has an effect on reducing the pain scale in the elderly with osteoarthritis. It is hoped that the results of this study can be disseminated by providing counseling to the community where warm red ginger compresses can be used as a non-pharmacological technique to reduce pain in elderly people with osteoarthritis so that it can improve health services

The Effectiveness of Progressive Muscle Relaxation on Reducing Joint Pain in the Elderly at Jember Nursing Home

Increasing age and the aging process can cause various problems, especially physical dissatisfaction, which results in impaired musculoskeletal function, namely joint pain which makes the elderly experience problems in carrying out daily activities. Pain management with non-pharmacological nursing actions that can be used to relieve joint pain in the elderly, namely progressive muscle relaxation therapy (ROP). This study aims to determine the impact of progressive muscle relaxation (ROP) on joint pain in the elderly at Wisma Melati UPT PSTW Jember. This research was conducted quantitatively with the type of quasi-experimental research using a research design approach (one group pre-test and post-test design). Samples were taken by purposive sampling. The sample population used in this study was elderly at Wisma Melati UPT PSTW Jember, with nine elderly people selected. The results showed that the respondents who took part were on average 77.11 years old (SD=5.732), the youngest was 70 years old and the oldest was 90 years old. The average value of the pain scale before performing progressive muscle relaxation (ROP) is 3.44 with a minimum value of 2 and a maximum value of 5. The mean value of the pain scale after administration of progressive muscle relaxation (ROP) is 2.67 with a minimum value of 0 (no pain) and the maximum value is 5. Based on the results of the analysis test using the t-test paired sample test the results of the joint pain scale before and after progressive muscle relaxation (ROP) was carried out, namely 0.0023 (p &lt;0.005). There was a change or difference in the decrease in pain scale before and after giving progressive muscle relaxation therapy (ROP) to the elderly.

Promising minimally invasive treatment modalities for symptomatic temporomandibular joint disc displacement with reduction: a randomized controlled clinical trial

BackgroundPain and clicking are the primary complaints in patients suffering from temporomandibular joint disc displacement with reduction (DDwR), negatively affecting the patients' quality of life, making the treatment essential. This prospective randomized controlled trial (RCT) was conducted to evaluate the effectiveness of botulinum toxin type-A (BTX-A) and low level laser therapy (LLLT) in comparison to anterior repositioning appliance (ARA) for the treatment of DDwR.MethodsA total of 27 patients were randomly allocated to 3 groups; ARA (control group), BTX-A, and LLLT; with 9 patients each. All patients were evaluated before and 3 months after the treatment using a visual analogue scale (VAS) and magnetic resonance imaging (MRI).ResultsAt 3 months follow-up, all groups showed a significant reduction in pain assessed by VAS (P = 0.007). Measured on MRI, there was a significant improvement in disc position and joint space index (JSI) in BTX-A group (P < 0.001, P = 0.011) and LLLT group (P = 0.002, P = 0.017) in comparison to the control group (P = 0.087, P = 0.066) respectively. As for time of recovery, a statistically significant difference was observed in BTX-A group (P < 0.001) and LLLT (P < 0.001) group in comparison to ARA group, which showed the most prolonged duration for reduction of DDwR symptoms.ConclusionWe concluded that BTX-A and LLLT could be considered effective alternative treatment modalities to ARA regarding reducing joint pain, clicking, and improving disc position in patients with symptomatic DDwR.Trial registrationThis prospective double-blinded RCT has been registered at ClinicalTrials.gov with identification number: NCT05194488, 18/1/2022.

Photobiomodulation Therapy Using Infrared (808 nm) Low Level Laser Therapy Associated with Strength Training in Knee Osteoarthritis: A Randomized placebo-controlled clinical trial

Mechanisms for significant clinical and statistical benefits of photobiomodulation (PBMT) in the treatment of knee osteoarthritis (KOA) include anti-inflammatory effects, optimization of tissue repair, improved muscle function and analgesia. The effectiveness of (PBMT) associated with strength training (ST), in the form of strength training, has been investigated in randomized clinical trials, but the results are not well clarified. The aim of this study was to evaluate the effects of ST associated with PBMT on joint pain intensity, range of motion, physical function and muscle strength of the quadriceps femoris and hamstrings in patients diagnosed with KOA. Twenty-eight adult patients of both genders with KOA were randomly distributed in 2 treatment groups, performed 3 times a week, for 6 weeks: ST Group (ST), submitted to stretching, self- mobilization, muscle strengthening and sensorimotor training and ST and STP Group (STP), submitted to the same program as the ST followed by infrared laser irradiation (Therapy XT, DMC, São Carlos, Brasil, l= 808 nm, P= 100mW, 5 points in the medial joint region and 4 points lateral, 3 J/point, 30 s/point). Blinded evaluators assessed pain at movent and no movement and range of motion using Analogic Visual Scale and goniometry, respectively. To assess physical function, the WOMAC questionnaire (Western Ontario and MacMaster University Osteoarthritis Index) and functional tests were used: Sit and stand test; 2 min-walk test. The muscular strength of the quadriceps and hamstrings were measured using an isometric dynamometer. The evaluations were performed in 4 moments: before (EV0), during (EV1: 3 weeks of treatment), at the end (EV2: after 6 weeks of treatment) and 30 days after the end of treatment (follow-up). The STP group showed a significant reduction in pain intensity at rest and at movement in EV1, as well as, significant improvement in relation to stiffness, total WOMAC and knee flexion amplitude, an improvement in physical function and an increase in muscle strength of quadriceps femoris when compared to ST group (p &lt;0.05). In the assessment of the strength of the hamstring muscles, there was no significant difference between the groups at any time evaluated (p&gt; 0.05). ST associated with PBMT had greater effects in reducing joint pain intensity, active knee flexion, physical function and muscle strength, especially in the quadriceps femoris, than strength training alone in patients with KOA.

Application of Red Ginger Decorative Compress to Reduce Joint Pain in Osteoarthritis Patients in the Work Area Perumnas Public Health Center Lubuklinggau

Osteoarthritis is one of the most common types of arthritis, this condition causes joints to feel sore and stiff. Swelling can also occur in these joints. To determine the application of red ginger boiled compresses to reduce joint pain in Osteoarthritis sufferers in the Work Area of ​​the Public Health Center of Lubuklinggau City in 2021. Case study subjects used in family nursing case studies namely 2 families who experience osteoarthritis with knee pain problems on a scale of 4-5, female, 45-70 years old, have members who are more than 15 years old, can communicate well, do not suffer from complications of other diseases and do not take medication. Before the action is taken. Research results: during the application of red ginger decoction compresses are able to provide a comfortable effect and help in overcoming joint inflammation that occurs. The application of red ginger boiled compresses can reduce joint pain in osteoarthritis sufferers.

PROVISION OF INFRARED THERAPY AND ACUPRESSURE THERAPY TO REDUCE JOINT PAIN IN GUE VILLAGE

Joint pain is a prevalent disease among the elderly, and treatment can be carried out through pharmacological and non-pharmacological methods. Infrared and acupressure therapies are two effective solutions to alleviate this problem. In this community service, we utilized infrared therapy and acupressure therapy to reduce joint pain. A quasi-experimental study with a control group pretest-posttest design was conducted, and the therapy was administered five times. The activity took place on June 29, 2022, in Gue Village, Kuta Baro District, Aceh Besar, and was facilitated by D3 Nursing lecturers with the assistance of students. The study's findings indicate a decrease in the pain scale from an average of 5.30% before therapy to 2.40% after therapy among 20 elderly patients. This therapy can be imparted to health cadres in the community and is a viable option for managing joint pain.

PENERAPAN KOMPRES SERAI HANGAT UNTUK MENGURANGI NYERI SENDI PADA LANSIA DI PACITAN

&#x0D; &#x0D; &#x0D; &#x0D; Introduction: The number of elderly people who experience joint pain in the Tanjungsari Pacitan Health Center work area in 2019 totaled 313 patients, 2020 totaled 620 patients, 2021 totaled 337 patients, from this data the elderly who experience joint pain are female and male. Joint pain disease usually attacks the joint area, and if not treated quickly it will interfere with daily activities and interfere with comfort. Objectives: Describe the results of implementing the application of warm lemongrass compresses to reduce joint pain in the elderly. Methods; The type of research used in this research is descriptive with a case study design. Results: The pain scale before being given the application of warm lemongrass compresses on the pain scale respondents showed a moderate pain scale. The pain scale after being given a warm lemongrass compress shows a mild pain scale. There are differences in the level of pain scale development in respondents with joint pain before and after the warm lemongrass compress intervention. Conclusions:; There are differences in development before and after being given warm lemongrass compresses in the elderly.&#x0D; &#x0D; &#x0D; &#x0D;

Combining mussel with fucoidan as a supplement for joint pain and prediabetes: Study protocol for a randomized, double-blinded, placebo-controlled trial.

IntroductionPharmaceutical drugs are beneficial to inflammatory conditions but with side effects, which led to the search for alternative therapies. Perna canaliculus, the New Zealand green-lipped mussel, have shown promise in placebo-controlled trials for inflammatory conditions. Fucoidan, an extract from seaweed Undaria pinnatifida, has been found to have beneficial effects on joint pain and insulin resistance. However, green-lipped mussel and fucoidan have never been combined.Methods and analysisA parallel, two-arm, double-blind, randomized, placebo-controlled trial will be conducted in New Zealand to determine whether a food product supplemented with green-lipped mussel and fucoidan improves joint pain and/or insulin resistance. Those who are ethnically Chinese, are aged over 30 years, have prediabetes and hip or knee joint pain will be eligible to participate. They will be randomized at 1:1 ratio to consume either dark chocolate supplemented with 1000 mg mussel powder and 1000 mg fucoidan or dark chocolate with no active substances daily for 100 days. The primary endpoints are change in insulin resistance and patient-reported joint pain. Secondary endpoints include anthropometry, fasting glucose and insulin, HbA1c, inflammatory markers, satiety, quality of life, physical function, pain intensity, and analgesic medication use. A sample size of 150 (75 per arm) will provide 90% power at an overall significance level of 5% (two-sided) to detect a standardized effect size of 0.625 on either of the two co-primary outcomes allowing for 10% loss.Ethics and disseminationThe study was approved by the Health and Disability Ethics Committee (number: 20/STH/153). Results will be made available to participants, funders, and other researchers.DiscussionThis trial will provide data on the potential utility of a mussel-fucoidan supplement in reducing joint pain and/or insulin resistance, to inform the development of a supplemented food product suitable for the Chinese market.Clinical trial registrationhttps://trialsearch.who.int/Trial2.aspx?TrialID=ACTRN12621000413820, ANZCTR Registration: ACTRN12621000413820, on 15 April 2021.