The Spatial Governance and Planning System (SGPS) analysis was born in European studies, has reached a certain stage of maturity in Europe and can be adopted by researchers in other continents. Latin American and Caribbean (LAC) countries currently represent an interesting field to experiment with this analytical approach for several reasons. One of them is the ascertainment that LAC national SGPSs are deeply influenced by the ongoing national democratization which started after the demise of conservative right-wing authoritarian regimes, somehow belonging to the postcolonial political stream and pushed by imperialist and neocolonial pressures. By its own nature, democratization as a whole is an extremely complex, articulated, and multidimensional process that deserves to be treated ad hoc. Within democratization, this work merely considers the institutionalization of spatial governance and planning activities and processes and so, the Structure of SGPSs. Supposedly, the formation and functioning of institutions are central in the process of consolidation of a democratic state which ensures rights and redistributes resources to citizens. To do this, based on the reconstruction of the overall SGPSs of three different countries included in the doctoral thesis of the author, this article presents the analysis of the so-called “Structure” of the Brazilian, Bolivian and Cuban SGPSs. Arguably, the set of Structures of the SGPSs of these countries is especially representative of the wide range of the LAC national cases. In fact, Brazil, Bolivia, and Cuba are iconic cases of distinguished spatial configurations. Brazil, which has experienced industrialization, tertiarization and metropolisation, has become an emergent economy characterized by structured democratic public institutions. Despite a range of well-known redistributive policies, however, Brazilian society remains extremely unequal and stratified. Bolivia has experimented with the promotion of plurinationalism in political and social terms, potentially improving the reciprocal integration of different ethnic groups and cultures. Nevertheless, a great developmental delay is shown by social and economic indicators, if compared to other LAC countries. Cuba, which has experimented with its own form of socialism for decades, is still a socialist republic with tragic problems of widespread poverty in a flattened society. To analytically present the Structure of the three selected national cases, four main scopes of investigation were adopted: (i) National spatial configuration, (ii) Postcolonial legacy in spatial governance and planning, (iii) Spatial governance and planning as redistributive practices, (iv) Metropolitan governance. The identification of these scopes represented the first result of the field research carried out in 2018–2019 in those countries. Assumably, those four scopes are sufficiently comprehensive to describe the Structure of SGPS of a LAC national system and they help systematize at least the main “Structural” factors – which are described one-by-one in this article – and characterize the LAC SGPSs. The article presents the four scopes for each country, according to a case-by-case logic. After that, it analyses the four scopes simultaneously comparing the three cases. Based on the analytical comparison of the main factors from the four scopes, the article discusses a range of issues that emerged, to problematize and operate convenient generalizations on the quality and characterization of the Structure of national SGPSs.