Background: Oral mucositis is the commonplace problem of mass cancers’ chemotherapy. It begins five-10 days after the initiation of chemotherapy and lasts 7-14 days. Chemotherapy precipitated oral mucositis reasons the mucosal lining of the oral to atrophy and break down, forming ulcers. The take a look at is to evaluate the effectiveness of turmeric oral rinse and saline oral rinse on patents with chemotherapy precipitated oral mucositis in determined on sanatorium. Design: Casual research design was selected for the study; inclusion criteria were selected by non-probability sampling technique. Selection criteria: the inclusion criteria included Patients under chemo therapy with the age class above age class of 20-65 years and both the gender. Methods: A study was conducted patients with oral mucositis among patients receiving chemotherapy. The assessment tools were used national cancer institute oral mucositis grading scale. Results: From the findings of the have a look at, it can be concluded that the overall vicinity smart comparison among intervention class I and II imply percent score for pretest became 88%, revealing the difference of 59% in intervention class 47 % for numerical pain assessment scale. tremendously full-size variations had been discovered in experimental organization I. but, in treatment group II pretest rating become 25% while in submit-test it was sixty-one% revealing the difference of 36%. It depicts that the turmeric oral rinse was greater effective than saline oral rinse in lowering the extent of oral mucositis among affected person receiving chemo remedy. Paired t check score become 14.43 and 8.52 in intervention class I and II, when as compared to desk value (2.15) each are elevated. This suggests that there has been an effectiveness between submit test score of degree of oral mucositis among affected person receiving chemo therapy in intervention class I and II. paired and unpaired “t” check confirmed, there was a huge effectiveness of turmeric oral rinse is greater powerful than saline oral rinse on oral mucositis among patient receiving chemotherapy. Chi rectangular test confirmed handiest length of cancer (p>0.05) in both the class up and the boxcar variable haven't any good-sized association with the submit-check score of stage of oral mucositis in both intervention class I and II. Conclusion: The findings found out that imply publish check scores was 34.24±1.28 in intervention class I, in intervention class II publish- check rating changed into 24.07± 1.27 revealing the distinction of 36%. It depicts that the turmeric oral rinse became greater powerful than saline m oral outh rinse in lowering the extent of oral mucositis among patient taking chemotherapy.