1823 The effect of central hypervolemia with water immersion on oxygen uptake(˙VO2) and heart rate (HR) responses to arm cranking was investigated. Seven male recreational swimmers performed 6-minute arm cranking exercise corresponding to 80% ventilatory threshold in air (C trial) and immersed in 30°C water (WI trial) up to the xiphoid process after six minutes of sitting. ˙VO2 and HR responses to exercise were obtained from a mono-exponential fitting. Response was evaluated by the mean response time(MRT; sum of time constant and delay). There was no significant difference in˙VO2 and HR gains between C and WI trials (˙VO2 0.78 ± 0.1 1·min-1, 0.80 ± 0.21·min-1; HR 36 ± 7 bpm, 37 ± 8 bpm, respectively). The HR MRT was not significantly different between C and WI trials (17 ± 3 s, 19 ± 8 s, respectively), while ˙VO2 MRT was slower in WI than C trial (45 ± 6 s, 40 ± 6 s, respectively; p < 0.05). Considering that there was no difference in the oxygen utilization of working muscles between the two trials, these results indicate that increased O2 store and/or altered blood redistribution response(s) delayed the ˙VO2 response to arm cranking exercise.