Due to the fact that it serves as both a pump and a compressor, the helico-axial multiphase pump is better suited for mixed-transport oil-gas two-phase flow and is frequently used for deep-sea oil extraction. The gas–liquid separation caused by the asynchrony of the gas–liquid two-phase medium is the primary cause of the damage or failure of the helico-axial multiphase pump in the project, resulting in the pump's damage or inability to operate. To investigate the variation of phase separation in the helico-axial multiphase pump under diverse operating conditions, a test system was designed and the theory of fluid flow mechanics was applied. The effects of different flow fields on the energy conversion characteristics of the pump were investigated. The results indicate that the gas–liquid separation position in the impeller occurs near the 2/3 of the airfoil bone line. After the gas–liquid separation, gas mass will be formed, pocket flow will be readily induced, and the gas block-up phenomenon will result in energy loss in the compression unit. Simulations indicate that the static pressure recovery and total pressure loss in a diffuser fluctuate over time. The static pressure recovery efficacy of the diffuser is highest when the imported gas volume fraction is 10% and lowest when the imported gas volume fraction is 60%. On the surface of the impeller blade, perpendicular to the flow direction, the separation phenomenon near the hub side is more severe than that near the rim. Along the flow direction, the pattern of phase separation is comparable.
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