Abstract This study investigates the impact of energy renovation on the indoor air quality of an apartment building during the heating season. The study was performed in one residential building before and after its renovation. An evaluation of the indoor air quality was performed using objective measurements and a subjective survey. The concentration of CO2 was measured in the bedrooms, and a sampling of the total volatile compounds (TVOC) was performed in the living rooms of the selected apartments. Higher concentrations of CO2 and TVOC were observed in the residential building after its renovation. The concentrations of CO2, and TVOC in some of the cases exceeded the recommended maximum limits, especially after implementing energy-saving measures on the building. The average air exchange rate was visibly higher before the renovation of the building. The current study indicates that large-scale renovations may reduce the quality of an indoor environment in many apartments, especially in the winter season.