Since the development of relationships between the subjects of the international system (between states, between states and international organizations, between international organizations, etc.) is necessary and certain evaluation criteria (indicator indicators) should be determined. Researchers, who examine the between various states, often describe the as developing relations if there are no acute(sharp) crises in the chronological framework. However, in cases of serious crisis does not occur, such relationships can develop or weaken due to various factors. In this respect, it is imperative to determine indicators (evaluation indicators of international relations) to evaluate the periods of development and decline of with scientific methods between states, including participants (subjects) of the international system. It is possible to have up to an average of hundred indicators used to evaluate the movement of interstate relations. However, grouping these indicators is one of the important conditions for conducting a systematic analysis. In this sense, it is possible to divide the indicators used to determine the direction of action of interstate into three groups: Political indicators, Economic indicators and Social indicators. For the first time, it has been tried to determine main political indicators in the science of international and to apply them in the example of the between the Republic of Armenia and the Islamic Republic of Iran. For evaluation of the between the two countries an main indicators used the number of reciprocal visits at the level of heads of state and government, the number of meetings held by the senior representatives of the two countries in foreign countries and within the framework of the meetings of international organizations, number and rate of mutual expeditions of managers of institutions responsible for foreign policy and number of disscussing ideas, the number, scope and place of the documents signed between the two countries in the state administration syste and etc. others.