Receptive Phase Research Articles

From rejection to historicisation: the reception of Robert Owen’s ideas in the nineteenth-century Polish context

ABSTRACT The main aim of this article is to investigate the reception of Owen’s ideas in the nineteenth-century Polish context. I argue that Owen’s ideas did not attract as much attention as those of, amongst others, Charles Fourier, Félicité de Lamennais, or – in the second half of the century – Karl Marx. Despite being overshadowed by other Romantic socialists, Owen’s reception in Poland can be described as having been marked by three phases. Though we can determine the general direction of this reception, we can only demarcate the rough time frames of it. The first phase may be traced from 1830 until around 1860. It was marked by Polish radicals’ rejection of Owen’s ideas. The phase, which may be dated from roughly 1848, saw the reception of and critical engagement with Owen’s ideas by Polish conservatives. Ironically, conservatives represented the first political current in the Polish context, which made a real effort to analyse and engage with his ideas seriously. Finally, the third phase of reception was constituted by Marxist and modern socialists, who, in seeing themselves at the end of an historical teleology, read Owen, and other early socialists, as their ideological forefathers.

Pollination of cycads in an urban environment

Research on urban systems has documented the contributions of cities as sites where insect pollinators undergo their life cycles, contributing to the reproduction of many groups of plants. However, reports of plants whose reproduction is assisted by specialist pollinators under conditions prevalent in cities are scarce. Cycads and insect pollinators are threatened mainly by loss and modification of their habitats. Here, we describe two cases in which cycad species from two genera distributed in Mexico (Ceratozamia tenuis (Dyer) D.W. Stev. & Vovides and Dioon edule Lindl.) reproduce and germinate successfully in urban areas, aided by insects, near their natural distribution areas. The plants examined were artificially planted in different gardens within the city of Xalapa-Enríquez. We found that specimens two genera of insect pollinators, Pharaxonotha sp. (Erotylidae: Pharaxonothinae) on C. tenuis, and Parallocorynus sp., (Belidae: Oxycoryninae) on D. edule, can survive in cycad pollen strobili, maintaining ecological interactions as they would occur in wild, conserved environments. In addition, we found beetles in ovulate strobili during the pollen receptivity phase, which suggests that they effectively reach ovulate strobili with pollen from pollen strobili. Characterization of this gymnosperm–beetle pollination system, which is unexpected in urban areas due the effects of human disturbance on insect communities, could promote new conservation biology research on flagship species in environments and landscapes shaped by anthropogenic impacts.

Autistic Traits Affect Reward Anticipation but not Reception

Autism spectrum conditions (ASC) have been linked to aberrant reward processing, but it remains unclear whether it is a general dysfunction or limited to social stimuli, and whether it affects both phases of reward processing, namely anticipation and reception. We used event-related brain potentials and a population-based approach to investigate reward anticipation and reception to socially relevant (i.e., picture of experimenter’s face showing approval/disapproval) and monetary rewards in 51 neurotypical individuals with varying levels of autistic traits. Higher autistic traits were associated with enhanced reward anticipation across reward types in the early anticipation phase (triggered by incentive cues), but not in the late anticipation phase (directly before reward reception), as reflected by the CNV component. The P3 component in response to reward reception showed a general increase for monetary outcomes, which was not modulated by autistic traits. These results suggest that higher autistic traits are related to enhanced reward anticipation, but do not modulate reward reception. No interaction between reward types and autistic traits was observed. We propose that the relevance of social rewards had higher reward value than commonly used pictures of strangers, which specifically normalised responses for individuals with high autistic traits.

Human embryonic stem cell–derived blastocyst-like spheroids resemble human trophectoderm during early implantation process

To study the use of human embryonic stem cell-derived trophoblastic spheroids (BAP-EB) as human blastocyst surrogates for studying early implantation and trophoblast development. Laboratory study. University research laboratory. Infertile invitro fertilization patients donating endometrial aspirates and human embryonic stem cells (hESCs: VAL3 and H9/WA09). In BAP-EB derived from hESC, transcriptomes analyzed by next-generation RNA sequencing, effects of Hippo signaling pathway studied by a YAP inhibitor, comparison of attachment of BAP-EB onto primary endometrial epithelial cells (EEC) collected at prereceptive and receptive phases, and antibody blocking assay used to study the molecule(s) involved in BAP-EB attachment. Gene expression profiles and endometrial cell attachment rates. The BAP-EB differentiation protocol for VAL3 could be used to induce trophoblast differentiation in another hESC line, H9. Transcriptomic analysis showed that the epiblast signature gene expression was reduced while that of the trophoblast was induced during BAP-EB differentiation. Specifically, trophectoderm signature genes were induced in BAP-EB at 48 hours and 72 hours after induction of differentiation. The Hippo signaling pathway was one of the pathways induced during BAP-EB differentiation, and YAP1 inhibitor statistically significantly reduced attachment, outgrowth, and trophoblast gene expressions of BAP-EB. A statistically significantly higher number of BAP-EB derived from both VAL3 and H9 attached onto receptive EEC than prereceptive EEC. The antibody blocking assay demonstrated that endometrial E-cadherin might be critical in early implantation. The data suggest that BAP-EB possesses a trophectoderm-like signature, which supports the use of BAP-EB as a blastocyst surrogate for the study of trophoblast development and endometrial receptivity.

MicroRNAs in Small Extracellular Vesicles Indicate Successful Embryo Implantation during Early Pregnancy.

Synchronous communication between the developing embryo and the receptive endometrium is crucial for embryo implantation. Thus, uterine receptivity evaluation is vital in managing recurrent implantation failure (RIF). The potential roles of small extracellular vesicle (sEV) miRNAs in pregnancy have been widely studied. However, the systematic study of sEVs derived from endometrium and its cargos during the implantation stage have not yet been reported. In this study, we isolated endometrium-derived sEVs from the mouse endometrium on D2 (pre-receptive phase), D4 (receptive phase), and D5 (implantation) of pregnancy. Herein, we reveal that multivesicular bodies (MVBs) in the endometrium increase in number during the window of implantation (WOI). Moreover, our findings indicate that CD63, a well-known sEV marker, is expressed in the luminal and glandular epithelium of mouse endometrium. The sEV miRNA expression profiles indicated that miR-34c-5p, miR-210, miR-369-5p, miR-30b, and miR-582-5p are enriched during WOI. Further, we integrated the RIF’s database analysis results and found out that miR-34c-5p regulates growth arrest specific 1 (GAS1) for normal embryo implantation. Notably, miR-34c-5p is downregulated during implantation but upregulated in sEVs. An implication of this is the possibility that sEVs miR-34c-5p could be used to evaluate uterine states. In conclusion, these findings suggest that the endometrium derived-sEV miRNAs are potential biomarkers in determining the appropriate period for embryo implantation. This study also has several important implications for future practice, including therapy of infertility.

Decision-Making While Passing and Visual Search Strategy During Ball Receiving in Team Sport Play

In many team sports, in which environmental change is constant, athletes selectively allocate attention between the approaching ball and other players, and constantly consistently making decisions regarding whom to pass the ball to. Few previous studies on decision-making in team sports such as soccer have included the ball reception phase. This study examined players’ visual search strategies during pass decisions. Using five-on-four soccer-specific film simulations from previously recorded real scenes, high-level players (HLPs) and middle-level players (MLPs) reacted to life-sized soccer scenes. We measured their visual search strategies in decision-making tasks involving ball reception and pass execution and collected their verbal reports. We employed a novel system wherein the ball is ejected toward participants according to the video clips in order to maintain perception–action coupling during the task. We found skill-based differences in decision-making accuracy, eye movement data, and verbal reports. HLPs demonstrated better decision-making than MLPs, and, in eye movement data, HLPs allocated more attention to nonmarked attackers ([ M] = 14.1, [ SD] = 4.8%, p < .001, η2 = 0.39), the teammate receiving the pass ( M = 18.4, SD = 4.3%, p < .05, η2 = 0.15), and opponents ( M = 14.6, SD = 6.3%, p < .05, η2 = 0.17) than did MLPs. Furthermore, according to verbal reports, HLPs tended to attend to information on opponent players. Thus, visual search strategies during ball reception suggest that the position and situation of teammates and opponents are the most important information sources for accurate and consistent pass decisions.

Proteomic Insights into Endometrial Receptivity and Embryo-Endometrial Epithelium Interaction for Implantation Reveal Critical Determinants of Fertility.

In vitro fertilization has overcome infertility issues for many couples. However, achieving implantation of a viable embryo into the maternal endometrium remains a limiting step in optimizing pregnancy success. The molecular mechanisms which characterize the transient state of endometrial receptivity, critical in enabling embryo-endometrial interactions, and proteins which underpin adhesion at the implantation interface, are limited in humans despite these temporally regulated processes fundamental to life. Hence, failure of implantation remains the "final frontier" in infertility. A human coculture model is utilized utilizing spheroids of a trophectoderm (trophoblast stem) cell line, derived from pre-implantation human embryos, and primary human endometrial epithelial cells, to functionally identify "fertile" versus "infertile" endometrial epithelium based on adhesion between these cell types. Quantitative proteomics identified proteins associated with human endometrial epithelial receptivity ("epithelial receptome") and trophectoderm adhesion ("adhesome"). As validation, key "epithelial receptome" proteins (MAGT-1/CDA/LGMN/KYNU/PC4) localized to the epithelium of receptive phase (mid-secretory) endometrium obtained from fertile, normally cycling women but is largely absent from non-receptive (proliferative) phase tissues. Factors involved in embryo-epithelium interaction in successive temporal stages of endometrial receptivity and implantation are demonstrated and potential targets for improving fertility are provided, enhancing potential to become pregnant either naturally or in a clinical setting.

ГЕНДЕРНАЯ ЛИНГВИСТИКА В ЛИНГВОЛИМОЛОГИЧЕСКОМ АСПЕКТЕ (НА МАТЕРИАЛЕ АНГЛОЯЗЫЧНОГО ДИСКУРСА)

The article shows that the gender-marked English-language network discourse can be represented as the Internet memes (textual units with indefinite subjectivity and short receptive phase addressed to universal audience). It is shown that gender nature of the Internet meme can manifest itself in different ways. The gender Internet meme is characterized by diffusion of its formal and (or) ontological boundaries. Such a feature of gender Internet memes is actualized only within the analysed subset while unveiling gender discourse, which in its turn is determined by limological parameters.

Transcriptome sequencing of endometrium revealed alterations in mRNAs and lncRNAs after ovarian stimulation.

Using RNA-sequencing analysis, we investigated the relationship between ovarian stimulation and endometrial transcriptome profiles during the window of implantation (WOI) to identify candidate predictive factors for the WOI and to optimize timing for embryo transfer. Twelve women with normal basal hormone levels and regular ovulation were randomly assigned into three groups based on sampling time: late-proliferate phase (P group), and receptive phase in natural cycles (LH+7, N group) and stimulated cycles (hCG+7, S group). Transcriptome profiles of mRNAs and long non-coding RNAs (lncRNAs) were then compared among the three groups. Validation was performed using real-time qPCR. Comparison of transcriptome profiles between the natural and stimulated endometrium revealed 173 differentially expressed genes (DEGs), with a > 2-fold change (FC) and p < 0.05, under the influence of supraphysiological estradiol (E2) induced by ovarian stimulation. By clustering and KEGG pathway analysis, molecules and pathways associated with endometrial receptivity were identified. Of the 39 DEGs common to the three groups, eight genes were validated using real-time PCR. ESR1, MMP10, and HPSE were previously reported to be associated with endometrial receptivity. In addition, three novel genes (IL13RA2, ZCCHC12, SRARP) and two lncRNAs (LINC01060, LINC01104) were new potential endometrial receptivity-related markers. Using mRNA and lncRNA sequencing, we found that supraphysiological E2 levels from ovarian stimulation had a marked impact upon endometrial transcriptome profiles and may result in a shift of the WOI. The precise mechanisms underlying the supraphysiological hormone-induced shift of the WOI require further research. ChiCTR180001453.

Nucleolar stress regulation of endometrial receptivity in mouse models and human cell lines

Embryo implantation is essential to the successful establishment of pregnancy. A previous study has demonstrated that actinomycin D (ActD) could initiate the activation of mouse delayed implantation. However, the mechanism underlying this activation remains to be elucidated. A low dose of ActD is an inducer of nucleolar stress. This study was to examine whether nucleolar stress is involved in embryo implantation. We showed that nucleolar stress occurred when delayed implantation was activated by ActD in mice. ActD treatment also stimulated the Lif-STAT3 pathway. During early pregnancy, nucleolar stress was detected in the luminal epithelial cells during the receptive phase. Blastocyst-derived lactate could induce nucleolar stress in cultured luminal epithelial cells. The inhibition of nucleophosmin1 (NPM1), which was a marker of nucleolar stress, compromised uterine receptivity and decreased the implantation rates in pregnant mice. To translate these mouse data into humans, we examined nucleolar stress in human endometrium. Our data demonstrated that ActD-induced nucleolar stress had positive effects on the embryo attachment by upregulating IL32 expression in non-receptive epithelial cells rather than receptive epithelial cells. Our data should be the first to demonstrate that nucleolar stress is present during early pregnancy and is able to induce embryo implantation in both mice and humans.

Sound in Literary Texts

This article defines the concept of auditivity in literary texts, both in the narrower sense of the term (the physically audible properties of a text) and in its wider sense (the potential ability of a text to create an auditive image in the mind of the recipient, thus conveying information in an aesthetic form, or contributing to this process). The article also investigates the possibilities of an intermedia typology of auditivity incorporating music and literature. This idea is built on the fact that both literature and music work with sound; they thus function as art forms which are close to their base material (Novak 2005: 26–34). I draw on a typology of literary/musical intermediality developed by Wolf (2011: 62–85), and I reach the conclusion that auditivity is a complex and complicated intermedia phenomenon which incorporates several intermedia types. The most explicit manifestation of the auditive properties of a text is on the level of structural plurimediality (sound poetry). Sound is also manifested implicitly in literary texts via intermedia imitations of acoustic structures (intermedia references in the form of imitations), which are very frequently accompanied by intermedia thematization. Auditivity in the process of literary communication has been investigated in the phases of auditivization (the deliberate creation of auditory properties in a literary work), reproduction and reception of literary texts. It has been determined that writers not only use traditional elements of poetic phonetics and phonology, but also engage in pure sonic experimentation. I reach the conclusion that the process of auditory emancipation of language is directly proportional to the loss of semantic properties by a text; literature thus comes close to the universality of musical communication.

O‑GlcNAc modification influences endometrial receptivity by promoting endometrial cell proliferation, migration and invasion.

O‑linked β‑N‑acetylglucosamine (O‑GlcNAc) modification is a dynamic post‑translational modification process that is involved in many crucial biological processes, including cell cycle regulation, nutrient metabolism and extracellular signaling. This dynamic modification is dependent on the ambient glucose concentration and is catalyzed and removed by O‑GlcNAc transferase(OGT) and O‑GlcNAcase (OGA), respectively. The present study aimed to determine the role of O‑GlcNAcylation during embryo implantation by inhibiting or enhancing its function and expression. The results revealed that the expression of O‑GlcNAc‑modified proteins in the human secretory endometrium was higher than that of the endometrium during the proliferative phase, as determined via western blotting and immunohistochemistry. Additionally, the level of endometrial O‑GlcNAc modification increased gradually from the pre‑receptive to the receptive phase, which was then decreased during the non‑receptive phase. In endometrial cells, RNA interference was utilized to reduce the expression of two key O‑GlcNAc synthesis and decomposition enzymes, OGT and OGA, to indirectly increase or decrease levels of O‑GlcNAc modification. The results revealed that increasing the level of O‑GlcNAc modification enhanced cellular proliferation, migration, invasion and adhesion, thereby promoting embryo implantation. It is hypothesized that O‑GlcNAc modification serves an important role in the regulation of endometrial receptivity and embryo implantation. The results of the present study may have important implications for the understanding of female fertility and may help improve infertility treatments.

Spacing and Mate Attraction: Sex-Specific Function of Advertisement Calls in the Northern Giant Mouse Lemur (Mirza zaza)

It has been proposed that primates use advertisement calls exclusively to negotiate spacing, but the function of female calls has rarely been studied. Here, we investigated the function of male and female advertisement calls in the northern giant mouse lemur (Mirza zaza),a non-gregarious nocturnal primate from north-western Madagascar. We recorded advertisement calls and associated behaviours of 35 M. zaza individuals at the Duke University Lemur Center. We found that females of M. zazaexclusively use their advertisement calls to advertise oestrus. In contrast, male advertisement calls appeared to be used in a spacing context. These findings show that primates can use their advertisement calls for both spacing and mate attraction, and that the sexes may differ in how they use these calls. The novel find of females of M. zazaattracting mates with loud advertisement calls contrasts with many non-primate taxa, where acoustic mate attraction is usually a function of male advertisement calls, and with other primates, where females use visual and olfactory cues to attract males. The loud female advertisement calls of M. zaza likely ensure mating success during the short receptive phase in this non-gregariously foraging, nocturnal primate.

Endometrial genome-wide DNA methylation patterns of Guanzhong dairy goats at days 5 and 15 of the gestation period

Uterine receptivity for the embryo is established and maintained through a series of precise cellular and molecular events, such as DNA methylation. There have been no studies to elucidate entire genome DNA methylation changes associated with embryo receptivity development of the endometrium (RE). In the present study, there was development of a complete genome-wide DNA methylome maps of the RE using whole-genome bisulphite sequencing and bioinformatics analysis. As many as 163.06 Gb of sequencing data averaging 81.53 Gb per sample were obtained for genome bisulphite sequencing of endometrium samples. There were distinct genome-wide DNA methylation patterns in pre-receptive endometrium (PE; Day 5 of gestation) and RE (Day 15 of gestation). There were as many as 16,467 differentially methylated regions (DMRs); 21,391 DMRs were less methylated in RE samples compared with PE samples (P-values ≤ 0.05 and |log2 (fold change)| ≥ 2). Compared with PE samples, methylation ratios of IGF2BP2, ACOX2, PTGDS, VEGFB and PTGDR2 genes were markedly less in RE samples (P-value ≤ 0.05 and |log2 (fold change)| ≥ 2). Conversely, in RE samples there was a markedly greater methylation ratio of IGFBP3 and IGF1R genes. The results of KEGG analysis indicated that these genes were involved in the signalling pathways for insulin, mitogen-activated protein kinase, gonadotropin-releasing hormone, vascular endothelial growth factor and progesterone-mediated oocyte maturation, which participated in differential regulation of goat endometrial development during receptive and prereceptive phases. The results of previous and the present study indicate resulting proteins of IGF2BP2, PTGDS, VEGFB, PGR, IGFBP3 and IGF1R gene expression may have important functions in regulating endometrial receptivity for the embryo.

MiR-29c overexpression and COL4A1 downregulation in infertile human endometrium reduces endometrial epithelial cell adhesive capacity in vitro implying roles in receptivity

The endometrium is a highly complex tissue that is vulnerable to subtle gene expression changes and is the first point of contact for an implanting blastocyst. Successful blastocyst implantation can only occur when the endometrium is receptive during a short window with each menstrual cycle. microRNAs are small, non-coding RNAs that negatively regulate their gene targets. miR-29c has previously been identified to be differentially regulated across the fertile menstrual cycle, however it has not been investigated in association with infertility. We hypothesised that miR-29c dysregulation in the infertile endometrium would negatively influence endometrial adhesion and blastocyst implantation outcomes during the mid-secretory, receptive phase. miR-29c expression was elevated in early and mid-secretory phase infertile endometrium and localised to the epithelial compartments of endometrial tissue. Overexpression of miR-29c in vitro impaired endometrial epithelial adhesion, and reduced collagen type IV alpha 1 (COL4A1) mRNA expression. COL4A1 was immunolocalised to the luminal and glandular epithelial basement membranes in early and mid-secretory phase fertile and infertile endometrium for the first time. Knockdown of COL4A1 impaired endometrial epithelial adhesion suggesting a role in endometrial receptivity and implantation. Our data suggests miR-29c overexpression with infertility may impair the adhesive capacity of the endometrium, potentially contributing to implantation failure and infertility.

MicroRNA Biogenesis Machinery Is Dysregulated in the Endometrium of Infertile Women Suggesting a Role in Receptivity and Infertility.

MicroRNAs (miRs) regulate endometrial function and their dysregulation could underlie unexplained infertility in women. Ribonucleases including DICER and DROSHA, and the proteins, ARGONAUTE 1 (AGO 1) and 2 (AGO 2) regulate the biogenesis/maturation of miRs. We aimed to elucidate the expression and localization of miR biogenesis machinery components during the human menstrual cycle and compare their levels in endometrium from women with normal fertility and primary unexplained infertility. miR biogenesis components were measured by quantitative-RT-PCR and immunohistochemistry. In the endometrium of women with normal fertility, DROSHA immunolocalized maximally to the epithelium during the early and mid-secretory phases compared with the proliferative and late-secretory phases. Stromal DICER immunostaining intensity was higher in the late-secretory phase compared with all other phases in fertile women. DROSHA mRNA was reduced in the mid-secretory-infertile whole endometrial tissue (has all cells of the tissue), and primary epithelial and stromal cells while no differences were found in DICER, AGO1, and AGO2 mRNA. In the luminal epithelium, DROSHA staining intensity was reduced in early and mid-secretory-infertile while DICER staining was reduced in the early secretory-infertile compared with their respective fertile groups. DICER and DROSHA were dynamically regulated across the menstrual cycle and reduced levels during receptivity phase could underlie implantation failure/infertility.

MUC20 expression marks the receptive phase of the human endometrium.

How does mucin MUC20 expression change during the menstrual cycle in different cell types of human endometrium? Study involved examination of MUC20 expression in two previously published RNA-seq datasets in whole endometrial tissue (n = 10), sorted endometrial epithelial (n = 44) or stromal (n = 42) cell samples. RNA-Seq results were validated by quantitative reverse transcription polymerase chain reaction (qRT-PCR) in whole tissue (n = 10), sorted epithelial (n = 17) and stromal (n = 17) cell samples. MUC20 protein localization and expression were analysed in human endometrium by immunohistochemical analysis of intact endometrial tissue (n = 6) and also Western blot of cultured stromal and epithelial cells (n = 2). MUC20 is differentially expressed in the endometrium between the pre-receptive and receptive phases. We show that MUC20 is predominantly expressed by epithelial cells of the receptive endometrium, both at the mRNA (RNA-Seq, P = 0.005; qRT-PCR, P = 0.039) and protein levels (Western blot; immunohistochemistry, P = 0.029). Our results indicate MUC20 as a novel marker of mid-secretory endometrial biology. We propose a model of MUC20 function in the hepatocyte growth factor (HGF)-activated mesenchymal-epithelial transition (MET) receptor signalling specifically in the receptive phase. Further investigations should reveal the precise function of MUC20 in human endometrium and the possible connection between MUC20 and HGF-activated MET receptor signalling. MUC20 could potentially be included in the list of endometrial receptivity markers after further clinical validation.

Analyses of circRNA profiling during the development from pre-receptive to receptive phases in the goat endometrium

BackgroundRecent studies have revealed that noncoding RNAs play important regulatory roles in the formation of endometrial receptivity. Circular RNAs (circRNAs) are a universally expressed noncoding RNA species that have been recently proposed to act as miRNA sponges that directly regulate expression of target genes or parental genes.ResultsWe used Illumina Solexa technology to analyze the expression profiles of circRNAs in the endometrium from three goats at gestational day 5 (pre-receptive endometrium, PE) and three goats at gestational day 15 (receptive endometrium, RE). Overall, 21,813 circRNAs were identified, of which 5,925 circRNAs were specific to the RE and 9,078 were specific to the PE, which suggested high stage-specificity. Further analysis found 334 differentially expressed circRNAs in the RE compared with PE (P < 0.05). The analysis of the circRNA-miRNA interaction network further supported the idea that circRNAs act as miRNA sponges to regulate gene expression. Moreover, some circRNAs were regulated by estrogen (E2)/progesterone (P4) in endometrial epithelium cell lines (EECs) and endometrial stromal cell line (ESCs), and each circRNA molecule exhibited unique regulation characteristics with respect to E2 and P4.ConclusionsThese data provide an endometrium circRNA expression atlas corresponding to the biology of the goat receptive endometrium during embryo implantation.

Joint Energy and SINR Coverage in Spatially Clustered RF-Powered IoT Network

Owing to the ubiquitous availability of radio-frequency (RF) signals, RF energy harvesting is emerging as an appealing solution for powering IoT devices. In this paper, we model and analyze an IoT network which harvests RF energy and receives information from the same wireless network. In order to enable this operation, each time slot is partitioned into charging and information reception phases. For this setup, we characterize two performance metrics: (i) energy coverage and (ii) joint signal-to-interference-plus-noise (SINR) and energy coverage. The analysis is performed using a realistic spatial model that captures the spatial coupling between the locations of the IoT devices and the nodes of the wireless network (referred henceforth as the IoT gateways), which is often ignored in the literature. In particular, we model the locations of the IoT devices using a Poisson cluster process (PCP) and assume that some of the clusters have IoT gateways (GWs) deployed at their centers while the other GWs are deployed independently of the IoT devices. The level of coupling can be controlled by tuning the fraction of total GWs that are deployed at the cluster centers. Due to the inherent intractability of computing the distribution of shot noise process for this setup, we propose two accurate approximations, using which the aforementioned metrics are characterized. Multiple system design insights are drawn from our results. For instance, we demonstrate the existence of optimal slot partitioning that maximizes the system throughput. In addition, we explore the effect of the level of coupling between the locations of the IoT devices and the GWs on this optimal slot partitioning. Particularly, our results reveal that the optimal value of time duration for the charging phase increases as the level of coupling decreases.

The specific character of code-switching in translation

The article addresses the question of the specific character of code-switching in translation. It is proposed that such switching be viewed as the switching of linguacultural codes. The following characteristics of linguacultural switching are identified: key role in the translation process, predictability, purposefulness, predetermined conditions, cyclical nature, additional mental load, and equal functioning of both translation directions. We attempt to provide a description of the underlying mechanisms and processes of linguacultural switching. The creation of the mental image of the source text and deverbalization are two interrelated processes that operate during the reception phase and determine the effectiveness of the switching of linguacultural codes. The moment of switching involves a series of purposeful mental operations aimed at orientation in the situation, anticipation of the switch, switching attention to the target culture, and the linguistic means it uses to describe a particular fragment of reality. These operations start the processes of probabilistic forecasting and radiant thinking which lead to the actualization of translator’s linguistic and cultural experience, its retrieval from longterm memory and the associative search for linguistic means in the target language. Operations that occur during the production phase include the habit of inhibiting hasty conclusions, the processes of reductive reasoning, dynamic interlingual and intercultural comparison, and checking the target text against the mental image of the source text. These operate in parallel with the continuous functioning of working memory and mechanisms of linguacultural and operational control. A model demonstrating the process of linguacultural switching is presented.