Event Abstract Back to Event Broca's area is not necessary for articulation per se – Evidence from intracranial recordings N. M. Barbaro1, E. Chang1, N.E Crone2, A. Flinker3*, H. E. Kirsch4 and R.T Knight3, 5 1 University of California, Department of Neurosurgery, United States 2 Johns Hopkins University School of Medicine, Department of Neurology, Epilepsy center, United States 3 University of California, Helen Wills Neuroscience Institute, United States 4 University of California, Department of Neurology, Epilepsy center, United States 5 University of California, Department of Psychology, United States Paul Broca’s seminal work over 100 years ago still serves as the basis for the classical neuropsychological model of language processing. The advent of neuroimaging techniques has led to numerous studies revisiting this classical model. While Broca’s area has been implicated in both expressive and receptive function it is viewed as central to speech production. However, the temporal pattern of neural activation in Broca’s area during articulation remains unknown. We addressed this issue by recording electrocorticographic (ECoG) activity directly from the surface of Broca’s area in neurosurgical patients undergoing treatment for refractory epilepsy. We employed an auditory repetition task consisting of phonemes and words. Activity in Broca’s area commenced as early as 200 ms post-stimulus onset and continued for approximately 300 ms. Surprisingly, activity in Broca’s area was completely extinguished prior to articulation and remained inactive during articulation with neural activation seen only in mouth motor regions. Our results suggest that Broca’s area is not involved in the process of articulation per se but rather supports fine-tuned articulary motor planning prior to speaking. Conference: The 20th Annual Rotman Research Institute Conference, The frontal lobes, Toronto, Canada, 22 Mar - 26 Mar, 2010. Presentation Type: Poster Presentation Topic: Abstracts Citation: Barbaro NM, Chang E, Crone N, Flinker A, Kirsch HE and Knight R (2010). Broca's area is not necessary for articulation per se – Evidence from intracranial recordings. Conference Abstract: The 20th Annual Rotman Research Institute Conference, The frontal lobes. doi: 10.3389/conf.fnins.2010.14.00070 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 29 Jun 2010; Published Online: 29 Jun 2010. * Correspondence: A. Flinker, University of California, Helen Wills Neuroscience Institute, Berkeley, United States, adeen@berkeley.edu Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers N. M Barbaro E. Chang N.E Crone A. Flinker H. E Kirsch R.T Knight Google N. M Barbaro E. Chang N.E Crone A. Flinker H. E Kirsch R.T Knight Google Scholar N. M Barbaro E. Chang N.E Crone A. Flinker H. E Kirsch R.T Knight PubMed N. M Barbaro E. Chang N.E Crone A. Flinker H. E Kirsch R.T Knight Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.