Recent Version Research Articles

Evaluation of Sentinel-5P TROPOMI Methane Observations at Northern High Latitudes

The Arctic and boreal regions are experiencing a rapid increase in temperature, resulting in a changing cryosphere, increasing human activity, and potentially increasing high-latitude methane emissions. Satellite observations from Sentinel-5P TROPOMI provide an unprecedented coverage of a column-averaged dry-air mole fraction of methane (XCH4) in the Arctic, compared to previous missions or in situ measurements. The purpose of this study is to support and enhance the data used for high-latitude research through presenting a systematic evaluation of TROPOMI methane products derived from two different processing algorithms: the operational product (OPER) and the scientific product (WFMD), including the comparison of recent version changes of the products (OPER, OPER rpro, WFMD v1.2, and WFMD v1.8). One finding is that OPER rpro yields lower XCH4 than WFMD v1.8, the difference increasing towards the highest latitudes. TROPOMI product differences were evaluated with respect to ground-based high-latitude references, including four Fourier Transform Spectrometer in the Total Carbon Column Observing Network (TCCON) and five EM27/SUN instruments in the Collaborative Carbon Column Observing Network (COCCON). The mean TROPOMI–TCCON GGG2020 daily median XCH4 difference was site-dependent and varied for OPER rpro from −0.47 ppb to 22.4 ppb, and for WFMD v1.8 from 1.2 ppb to 19.4 ppb with standard deviations between 13.0 and 20.4 ppb and 12.5–15.0 ppb, respectively. The TROPOMI–COCCON daily median XCH4 difference varied from −26.5 ppb to 5.6 ppb for OPER rpro, with a standard deviation of 14.0–28.7 ppb, and from −5.0 ppb to 17.2 ppb for WFMD v1.8, with a standard deviation of 11.5–13.0 ppb. Although the accuracy and precision of both TROPOMI products are, on average, good compared to the TCCON and COCCON, a persistent seasonal bias in TROPOMI XCH4 (high values in spring; low values in autumn) is found for OPER rpro and is reflected in the higher standard deviation values. A systematic decrease of about 7 ppb was found between TCCON GGG2014 and GGG2020 product update highlighting the importance of also ensuring the reliability of ground-based retrievals. Comparisons to atmospheric profile measurements with AirCore carried out in Sodankylä, Northern Finland, resulted in XCH4 differences comparable to or smaller than those from ground-based remote sensing.

Applicability of STOPP/START prescribing criteria in integrated Swedish administrative health registries and a Swedish population-based cohort.

The STOPP/START criteria are frequently applied in observational studies to assess potentially inappropriate prescribing in older adults. This study aimed to assess the applicability of the three available STOPP/START versions in two distinct data sources. To evaluate the applicability of the three versions of STOPP/START criteria, we used two observational data sources: (i) Integrated Swedish administrative health registries (ISHR) encompassing routinely collected health data and (ii) the population-based Swedish National study on Aging and Care in Kungsholmen (SNAC-K), based on health professional-led clinical assessments. The Anatomical Therapeutic Classification code (ATC) was used to categorise medications. Diseases were categorised using the international classification of diseases version 10 (ICD10). The first STOPP/START version demonstrated an applicability rate of 80% in ISHR and 84% in SNAC-K. The second version demonstrated an applicability of 64% in ISHR and 74% in SNAC-K. The third version showed an applicability of 66% in ISHR and 77% in SNAC-K. Challenges in applicability included broad definitions, vague terminology, and the lack of information on disease severity, symptomatic traits, and stability of certain conditions. The applicability of the STOPP/START criteria in observational studies seems to have decreased in more recent versions of the tool. Population-based studies with comprehensive clinical assessments may offer higher applicability compared to studies based on administrative data. Future versions of the STOPP/START criteria should prioritise clear and unambiguous definitions to improve their applicability in research and promote result generalisability and comparability.

Complete-arch accuracy of seven intraoral scanners measured by the virtual-fit method

ObjectivesThis study compared the accuracy of seven intraoral scanners (IOS) by the virtual-fit method. MethodsFour maxillary arches with tooth abutments were scanned with an industrial reference scanner (n=1) and by Aoralscan3, EmeraldS, Helios600, Lumina, Mediti700, Primescan, and Trios5 IOSs (each n=12). Two complete-arch fixed frameworks were designed on each IOS scan with a 70 µm (group 70) and a 90 µm internal cement space (group 70+20, additional 20 µm at the margin). The virtual-fit method was comprised of superimposing the framework designs onto the reference scan using a non-penetrating algorithm simulating the clinical try-in. Internal and marginal gaps were measured. Precision was estimated by the mean absolute errors (MAE). ResultsIn group 70, Mediti700 (43 µm), Primescan (42 µm), and EmeraldS were in the best homogenous subset for the marginal gap, followed by the Lumina (67 µm), Aoralscan3 (70 µm), and Trios5 (70 µm), whereas Helios600 (118 µm) was in the third subset. Based on the MAE at the margin, Mediti700, Trios5, and EmeraldS were in the first-best homogenous subset, followed by Primescan. Lumina and Helios600 were in the third subset, and Aoralscan3 was in the fourth subset. In group 70+20, the marginal gap was significantly decreased for Lumina and Aoralscan3, whereas MAE significantly decreased for EmeraldS and Aoralscan3. The rank of IOSs was similar for the internal gap. ConclusionEmeraldS, Mediti700, Primescan, and Trios5 meet the marginal and internal fit criteria for fixed tooth-borne complete arch restorations. Increasing the cement space during design could enhance restoration fit. Clinical significanceThe virtual-fit alignment method can effectively evaluate the accuracy of different intraoral scanners, offering valuable clinical guidance for distinguishing among them. Recent software and hardware versions of long-standing IOS manufacturers are suitable for fabricating complete arch restoration.

Focused deterrence, strategic management, and effective gun violence prevention

AbstractResearch SummaryThe evaluation literature suggests that focused deterrence strategies are effective in reducing gun violence. However, focused deterrence is notoriously difficult to implement and sustain. The history of focused deterrence implementation failure raises questions about its viability as a gun violence prevention strategy. Stockton, California, implemented focused deterrence three times during the past 25 years. In its most recent version, Stockton officials explicitly designed the strategy to be a permanent feature of the city's violence prevention portfolio. Although program caseloads diminished over the course of the COVID‐19 pandemic and the strategy faced leadership and resource challenges, Stockton's efforts prevented the program from being discontinued and, for those gang members who did receive treatment, delivered a robust gun violence prevention strategy. A quasi‐experimental evaluation shows that treated gang members were less likely to be shot and reduced their violent offending relative to similar untreated gang members. The focused deterrence impacts also appear to spill over to gang members who were socially connected to treated gang members. Although Stockton experienced an increase in homicides over the course of the COVID‐19 pandemic, the increase was not as steep as other comparable California cities.Policy ImplicationsFocused deterrence strategies can be effective responses to gun violence problems when implemented properly. A priori planning is essential when jurisdictions prepare to adopt focused deterrence. Strategic management actions, such as maintaining a robust network of partnering agencies, developing accountability structures and sustainability plans, and conducting upfront and ongoing problem analysis, are critical elements that must be in place for focused deterrence to be effective and sustainable.

The clinical utility of handgrip strength as a malnutrition screening tool in hospitalized older adults: a cross-sectional study in Saudi Arabia.

Malnutrition is prevalent among hospitalized older patients. Early identification is therefore essential to implementing appropriate therapeutic interventions. This study aimed to explore the correlation between handgrip strength (HGS) and nutritional status in hospitalized older adults. This observational cross-sectional study was conducted at King Abdulaziz University Hospital, where a consecutive cohort of older adult inpatients was enrolled for participation. Shortly after admission, HGS and nutritional status were assessed using a dynamometer and the most recent version of the Mini-Nutritional Assessment Short Form (MNA-SF) test, respectively. Key anthropometric and biochemical indicators were also collected. A total of 135 consecutive patients were evaluated. Among participants with low HGS, 18 (16.22%) were malnourished, 43 (38.74%) were at risk of malnutrition, and 50 (45.05%) had normal nutrition status. The participants with low HGS had low hemoglobin, low lymphocyte levels, high creatinine levels, high BUN levels, high CRP levels, high HbA1c levels, and high vitamin B12 levels. Multiple logistic regression analysis showed that age, hemoglobin, and HbA1C were independently associated with low HGS. Based on the cut-off values for the HGS by the European Working Group on Sarcopenia in Older People-2 (EWGSOP2), low HGS showed high sensitivity to detect "malnourished and at risk of malnutrition" as well as "malnourished alone;" however, the specificity was low to exclude "malnourished and at risk of malnutrition" as well as "malnutrition alone." Age over 75 years, low hemoglobin, and elevated HbA1C levels were independent risk factors for low HGS. While HGS was sensitive in detecting malnutrition or risk, its specificity was low. Therefore, HGS may not be adequate as a standalone tool to assess nutritional status in hospitalized older adults. Replication of this study using locally reliable and validated HGS cut-off values is warranted to confirm these findings.

Early treatment for children with mental health problems and genetic conditions through a parenting intervention (The GAP): study protocol for a pragmatic randomized controlled trial

BackgroundChildren with genetic conditions are at increased risk for mental health and neurodevelopmental problems, often accompanied by significant parental distress. Genetic and family factors can impact children and parents’ mental health. Early parenting interventions, like the Incredible Years® programs, have demonstrated to improve parental distress and children’s mental health. The recent version for young children with language delays or autism spectrum disorder (IY-ASLD®) has shown to be feasible and effective to support parents in their children’s developmental trajectories. The effectiveness of treatments for children with genetic conditions and neurodevelopmental problems is largely unexplored, leaving significant gaps in evidence-based options. Clinicians lack guidance, especially when patients exhibit language or social communication impairments but do not meet diagnostic criteria for a full-blown autism spectrum disorder (ASD). We aim to fill this gap, providing evidence on the feasibility and effectiveness of the IY-ASLD® intervention for such patients.MethodsWe designed a prospective multicenter pragmatic randomized controlled trial including approximately 68 children aged 3 to 7 years, recruited from three tertiary care reference hospitals. Inclusion criteria will necessitate genetic confirmation of a neurodevelopmental disorder along with language, communication, or socialization difficulties. Individuals with an ASD diagnosis will be excluded. All subjects are included in a territorial register for rare conditions (ReMin, Registre de Malalties Minoritàries de Catalunya). Families will randomly be assigned to the intervention or the control group. The intervention will be held online by clinical psychologists and child and adolescent psychiatrists.DiscussionOur group has recently piloted the online implementation of the IY-ASLD® intervention for the first time in Spain, for parents of children with language delays, socialization difficulties, or ASD, but not genetically determined. Our multicenter research consortium is well-positioned to recruit patients with rare conditions and implement efficient treatment pathways within the National Health System. Given the geographical dispersion of families affected by rare conditions, the online format offers logistical advantages and improved therapy access, enhancing homogeneity across all patients. The results of this study will inform clinicians and policymakers about evidence-based treatment options for this vulnerable and overlooked group of young children.Trial registrationClinicalTrials.gov NCT06125093. Date of registration: first submitted 2023–10-23; first posted 2023–11-09. URL of trial registry record.

EQ-5D-5L Population Scores in Mainland China: Results From a Nationally Representative Survey 2021

ObjectivesThere is a lack of monitoring changes in the population scores of the most recent version, EQ-5D-5L, in mainland China. This study aimed to address this knowledge gap by assessing the EQ-5D-5L scores in mainland China using a nationally representative sample. MethodsData were extracted from the 2021 Survey of Health Index of Chinese Families, which covered 31 provinces/autonomous regions/municipalities in mainland China. The survey used a multistage quota sampling strategy encompassing 120 prefecture-level cities. Quotas were allocated to each prefecture-level city in accordance with the 2020 China Population Census. This approach resulted in a final sample of 11 030 eligible questionnaires. The utility index (UI) and EuroQol Visual Analog Scale (EQ VAS) scores were reported for the entire sample (age-gender-urban/rural weighted) and by the characteristics of the study participants. ResultsThe study participants had a weighted mean UI of 0.939 (SD 0.135) and EQ VAS score of 80.19 (SD 18.39). The most commonly reported problem was anxiety/depression (26.37%), whereas self-care was the least reported problem (6.18%). Those who were male, were younger, lived without chronic conditions and disabilities, had higher levels of education, earned higher monthly household income, and were covered by basic medical insurance for urban employees had higher scores in both the UI and EQ VAS. ConclusionThis study revealed slightly lower UI scores despite a much higher drop in EQ VAS scores whereas China maintained minimum cases of COVID-19 in 2021 compared with the population norms recorded in 2019. Further studies are warranted to unveil the full impacts of COVID-19 outbreaks.

Accretion of Meteoric Organic Matter at the Surface of Mars and Potential Production of Methane by Ultraviolet Radiation

In this study, a comprehensive model of the meteoric organic cycle on Mars for the current geological period is developed, which characterizes the ablation of exogenous organic matter in the upper atmosphere, the accretion of intact carbon at the surface, and the potential production of methane by UV photolysis from the surface reservoir. The model accounts for both the latitudinal and seasonal variation of the meteoroids’ input from the most relevant populations in the inner solar system. A recent version of the University of Leeds Chemical Ablation Model, which includes a semiempirical model to describe the pyrolysis kinetics of the meteoric organic matter, is then combined with this meteoroid input function and a semiempirical model that quantifies the UV production of methane. The minimum and maximum accretion rates of organics are between 18 and 90 kg sol−1 at aphelion and 45–134 kg sol−1 at the first crossing of the ecliptic plane. The resulting mixing ratios of carbon, in the top 200 μm of the surface layer, range from 0.09–0.43 ppm at 20°N to 4.8–8.9 ppm around the south pole. To be consistent with the methane upper limit of 0.02 ppbv measured by the NOMAD instrument on the ExoMars Trace Gas Orbiter, the UV photolysis yields for methane production need to be around 3% assuming a meteoric carbon content in comets of 25.6 wt% and an atmospheric lifetime of methane of 329 Earth yr. Alternatively, a laboratory estimate of 20% for the methane production yield would require a lifetime of 60 Earth yr.

Development of the assessment scale for preterm oral feeding readiness (ASPOFR)

ObjectiveThe study was planned to develop measurement tool for assessing the readiness of preterm infants to transition to oral feeding. MethodsA literature review and a panel of experts were used to develop the questionnaire to analyze the Assessment Scale for Preterm Oral Feeding Readiness (ASPOFR). The recent version of the questionnaire was composed of 16 items and applied to a sample of 153 infants. ResultThe content validity ratio of the scale items ranged from 0.85 to 1.00 and the content validity index was 0.98. The Cronbach's alpha for the ASPOFR scores was 0.938. ROC was 95.5%, and an optimal cut-off value of ASPOFR was 20. ConclusionASPOFR has been verified to be an effective and accurate instrument to determine the initiation of oral feeding in preterm infants.

Prevalence of Internet Gaming Disorder and Its Impact on Routine Activities Among Dental Students in Belagavi, India: A Cross-Sectional Study.

Internet gaming has gained popularity since the millennium, greatly expanding both the game industry and the player base. Moreover, internet gaming disorder (IGD)is a condition included in the most recent version of the Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5) for further study. To assess the prevalence of IGD and its association with physical symptoms among dental students in Belagavi, India. A cross-sectional study was conducted among 385 dental students, chosen through simple random sampling. Data were gathered using a pre-validated, closed-ended questionnaire, incorporating the 9-item DSM-5 short version. The questionnaire was administered to undergraduate students during theory classes and collected after 10 minutes, while postgraduate students received it in their respective departments. To identify significant differences, Chi-square and analysis of variance(ANOVA) tests were applied, with statistical significance established at p ≤ 0.05. A total of 385 responses were collected, comprising 86 males (22.3%) and 299 females (77.7%). Among the respondents, 28 (7.2%) were diagnosed with IGD, while 123 (31.8%) were identified as risky gamers. Significant differences were found between disordered, risky, and normal gamers concerning sleep-related problems (p ≤ 0.05). The prevalence of IGD and risky gamers was 7.2% and 31.8% respectively. There was a significant association between disordered, risky, and normal gamers with daily routine activities.

What Are the Economic Impacts of Indonesia’s Export Ban? A Computable General Equilibrium Analysis

This study aims to assess the economic impact of the mineral export ban on Indonesia and other countries. The comparative-static version of the computable general equilibrium model (Global Tarde Analysis Project (GTAP)) is used to analyse the economic impact of the export ban, with a particular focus on GDP, welfare, terms of trade and external trade. The most recent GTAP version 9 database was used for the modelling simulations of the Indonesian export ban. The GTAP version 9 database has three reference years: 2004, 2007 and 2011. It already aggregates 140 regions and 57 sectors. The modelling simulation results show that the policy of bauxite, copper and tin export tyres benefits the Indonesian economy. Meanwhile, Indonesia’s export ban policy harmed the economies of other countries, particularly China, Japan, India, Korea and the EU-28.

Uncertainty in simulated brightness temperature due to sensitivity to atmospheric gas spectroscopic parameters from the centimeter- to submillimeter-wave range

Abstract. Atmospheric radiative transfer models are extensively used in Earth observation to simulate radiative processes occurring in the atmosphere and to provide both upwelling and downwelling synthetic brightness temperatures for ground-based, airborne, and satellite radiometric sensors. For a meaningful comparison between simulated and observed radiances, it is crucial to characterize the uncertainty in such models. The purpose of this work is to quantify the uncertainty in radiative transfer models due to uncertainty in the associated spectroscopic parameters and to compute simulated brightness temperature uncertainties for millimeter- and submillimeter-wave channels of downward-looking satellite radiometric sensors (MicroWave Imager, MWI; Ice Cloud Imager, ICI; MicroWave Sounder, MWS; and Advanced Technology Microwave Sounder, ATMS) as well as upward-looking airborne radiometers (International Submillimetre Airborne Radiometer, ISMAR, and Microwave Airborne Radiometer Scanning System, MARSS). The approach adopted here is firstly to study the sensitivity of brightness temperature calculations to each spectroscopic parameter separately, then to identify the dominant parameters and investigate their uncertainty covariance, and finally to compute the total brightness temperature uncertainty due to the full uncertainty covariance matrix for the identified set of relevant spectroscopic parameters. The approach is applied to a recent version of the Millimeter-wave Propagation Model, taking into account water vapor, oxygen, and ozone spectroscopic parameters, though the approach is general and can be applied to any radiative transfer code. A set of 135 spectroscopic parameters were identified as dominant for the uncertainty in simulated brightness temperatures (26 for water vapor, 109 for oxygen, none for ozone). The uncertainty in simulated brightness temperatures is computed for six climatology conditions (ranging from sub-Arctic winter to tropical) and all instrument channels. Uncertainty is found to be up to few kelvins [K] in the millimeter-wave range, whereas it is considerably lower in the submillimeter-wave range (less than 1 K).

The Looping Effects of Medicalizing Grief

The most recent versions of official psychiatric diagnostic guidelines include a new addition: Prolonged Grief Disorder (PGD). PGD is controversial due to concerns about harmful looping effects. Some opponents of PGD’s inclusion in the DSM worry that the diagnosis may pathologize normal human experiences and alienate grievers from their grief. This paper argues that these concerns are less troubling than they initially appear (in part because they assume an unhelpful, and conceptually optional, background understanding of health conditions as pathologies) and calls attention to overlooked beneficial looping effects that might be achieved by medicalizing (some) experiences of grief.

Using machine learning to improve the diagnostic accuracy of the modified Duke/ESC 2015 criteria in patients with suspected prosthetic valve endocarditis – a proof of concept study

IntroductionProsthetic valve endocarditis (PVE) is a serious complication of prosthetic valve implantation, with an estimated yearly incidence of at least 0.4-1.0%. The Duke criteria and subsequent modifications have been developed as a diagnostic framework for infective endocarditis (IE) in clinical studies. However, their sensitivity and specificity are limited, especially for PVE. Furthermore, their most recent versions (ESC2015 and ESC2023) include advanced imaging modalities, e.g., cardiac CTA and [18F]FDG PET/CT as major criteria. However, despite these significant changes, the weighing system using major and minor criteria has remained unchanged. This may have introduced bias to the diagnostic set of criteria. Here, we aimed to evaluate and improve the predictive value of the modified Duke/ESC 2015 (MDE2015) criteria by using machine learning algorithms.MethodsIn this proof-of-concept study, we used data of a well-defined retrospective multicentre cohort of 160 patients evaluated for suspected PVE. Four machine learning algorithms were compared to the prediction of the diagnosis according to the MDE2015 criteria: Lasso logistic regression, decision tree with gradient boosting (XGBoost), decision tree without gradient boosting, and a model combining predictions of these (ensemble learning). All models used the same features that also constitute the MDE2015 criteria. The final diagnosis of PVE, based on endocarditis team consensus using all available clinical information, including surgical findings whenever performed, and with at least 1 year follow up, was used as the composite gold standard.ResultsThe diagnostic performance of the MDE2015 criteria varied depending on how the category of ‘possible’ PVE cases were handled. Considering these cases as positive for PVE, sensitivity and specificity were 0.96 and 0.60, respectively. Whereas treating these cases as negative, sensitivity and specificity were 0.74 and 0.98, respectively. Combining the approaches of considering possible endocarditis as positive and as negative for ROC-analysis resulted in an excellent AUC of 0.917. For the machine learning models, the sensitivity and specificity were as follows: logistic regression, 0.92 and 0.85; XGBoost, 0.90 and 0.85; decision trees, 0.88 and 0.86; and ensemble learning, 0.91 and 0.85, respectively. The resulting AUCs were, in the same order: 0.938, 0.937, 0.930, and 0.941, respectively.DiscussionIn this proof-of-concept study, machine learning algorithms achieved improved diagnostic performance compared to the major/minor weighing system as used in the MDE2015 criteria. Moreover, these models provide quantifiable certainty levels of the diagnosis, potentially enhancing interpretability for clinicians. Additionally, they allow for easy incorporation of new and/or refined criteria, such as the individual weight of advanced imaging modalities such as CTA or [18F]FDG PET/CT. These promising preliminary findings warrant further studies for validation, ideally in a prospective cohort encompassing the full spectrum of patients with suspected IE.

A sufficient descent hybrid conjugate gradient method without line search consideration and application

PurposePrevious RMIL versions of the conjugate gradient method proposed in literature exhibit sufficient descent with Wolfe line search conditions, yet their global convergence depends on certain restrictions. To alleviate these assumptions, a hybrid conjugate gradient method is proposed based on the conjugacy condition.Design/methodology/approachThe conjugate gradient (CG) method strategically alternates between RMIL and KMD CG methods by using a convex combination of the two schemes, mitigating their respective weaknesses. The theoretical analysis of the hybrid method, conducted without line search consideration, demonstrates its sufficient descent property. This theoretical understanding of sufficient descent enables the removal of restrictions previously imposed on versions of the RMIL CG method for global convergence result.FindingsNumerical experiments conducted using a hybrid strategy that combines the RMIL and KMD CG methods demonstrate superior performance compared to each method used individually and even outperform some recent versions of the RMIL method. Furthermore, when applied to solve an image reconstruction model, the method exhibits reliable results.Originality/valueThe strategy used to demonstrate the sufficient descent property and convergence result of RMIL CG without line search consideration through hybrid techniques has not been previously explored in literature. Additionally, the two CG schemes involved in the combination exhibit similar sufficient descent structures based on the assumption regarding the norm of the search direction.

A Study On Knowledge Base and Skill Development in Financial Accounting Using The SPSS Method

The topics of growth and learning, practical proficiency in theory, supervision and leadership, awareness of policies and procedures, and organizational awareness are all included under the heading of knowledge and skill development. It is helpful to have a solid skill set to develop personally, establish a network, and learn managerial and interpersonal skills. Neither schooling nor formal instruction is required for the development of these abilities. Knowledge is information stored in long-term memory and accessed when necessary. Knowledge and comprehension are expressed through action, conduct, behavior, and the ability to understand how well something is done. The practice Financial accounting is the process of documenting, gathering, and summarizing multiple transactions occurring from company activities throughout time. The three types of accounting that a corporation might use to track its revenue are administrative accounting, financial accounting, and cost accounting. An ongoing feedback and practice cycle is necessary for learning new abilities. Self-regulation, functional, and specialized knowledge are the three types of skills. Functional talents are intrinsic aptitudes or abilities that develop with instruction and practice. Strong work ethic, self-motivation, adaptability, perseverance, and critical thinking in a team are all desirable qualities. A knowledgeable and effective time manager is also essential. This essay presents the findings of an examination of the fundamental knowledge, skills, and technique for accounting practice as seen by students. Notwithstanding some differences in opinion among the respondent businesses about the significance of these knowledge and skills, respondents generally agreed on a range of information and abilities essential to the practice of accounting students. The results also show that respondents are disappointed with the state-of-the-art delivery of necessary knowledge and skills. One of the main benefits of education and improvement is productivity. Personnel can perform their duties successfully and effectively when they possess the required expertise and understanding. Efficiency gains free up more time to enhance operations and increase income. SPSS statistics is a data management, advanced analytics, multivariate analytics, business intelligence, and criminal investigation developed by IBM for a statistical software package. A long time, spa inc. Was created by, IBM purchased it in 2009. The brand name for the most recent versions is IBM SPSS statistics. Evaluation parameters taken as Financial Accounting Knowledge, Financial Development Knowledge, Management in accounting, Taxes management and Business Law Knowledge. The Cronbach's Alpha Reliability result. The overall Cronbach's Alpha value for the model is .541 which indicates 54% reliability. From the literature review, the above 46% Cronbach's Alpha value model can be considered for analysis. The overall Cronbach’s alpha value for the model was .490, indicating 50% reliability. From the literature review, the above Cronbach’s alpha value of 46% can be considered to analyze the model.

Questioning the Emergence of Time

AbstractThe Evolving Block Universe is a model where spacetime continuously emerges leading to a ‘growth’ of spacetime by which there is a passage of time. Its most recent version extends ideas on the passage of time and the various arrows of time (determined by the cosmological evolution of the whole universe). Attention is drawn to some principal problems with this model, especially how the present moment and the passage of time are defined.

Non-degenerate necessary conditions for non-convex differential inclusions

This paper concerns dynamic optimization problems with pathwise state constraints, in which the dynamics are formulated as a differential inclusion. First order necessary conditions of optimality are available for these problems. Foremost among these conditions is the Euler Lagrange inclusion (combined with a transversality and Weierstrass conditions), which improves on earlier conditions such as Clarke's Hamiltonian inclusion. The most recent version of the Euler Lagrange inclusion (which we call the standard Euler Lagrange condition) has been validated under unrestrictive conditions, which allow the velocity sets of the differential inclusion to be non-convex. If the initial state is fixed and located in the boundary of the state constraint set then the Euler Lagrange inclusion conveys no information about minimizers. This is the degeneracy phenomenon for state constrained dynamic optimization. The non-degenerate necessary conditions literature provides additional conditions, to supplement the standard necessary conditions. These typically identify some properties of the boundary values of the maximized Hamiltonian which ensure non-triviality of the necessary conditions, under a simple controllability hypothesis. Non-degenerate conditions, incorporating the Euler Lagrange inclusion are currently available only under the hypothesis that the velocity sets are convex. Using new perturbation techniques, we derive a non-degenerate Euler Lagrange condition that is valid for non-convex velocity sets. These conditions bring into line non-degenerate optimality conditions for differential inclusion problems with those for problems involving controlled differential equations which have previously been validated for non-convex velocity sets.

What secondary research evidence exists on the effects of forest management after disturbances: a systematic map protocol

BackgroundForest disturbances are projected to increase in intensity and frequency in the upcoming decades. The projected change in disturbance regimes is expected to alter the provision of ecosystem services and affect biodiversity. Both are critical for forest ecosystems to provide livelihoods for human societies. Forest management after natural disturbances shapes successional pathways of forest ecosystems. Therefore, the management of post-disturbance sites deserves critical attention to avoid negative effects of management interventions on ecosystem services and biodiversity. The two most common management interventions after natural disturbances are salvage logging (comparator: no salvage logging) and tree planting (comparator: natural regeneration). This planned systematic map of reviews aims to aggregate the existing evidence syntheses on the implications of common forest management interventions after natural disturbances on successional trajectories with regard to selected ecosystem services and biodiversity. Evidence-based post-disturbance management is highly relevant for protected area management as well as for the management of commercial forests.MethodsWe will systematically search the databases Scopus, Web of Science Core Collection and the Forest Science Collection of the CABI Digital Library for reviews and meta-analyses (after 2003). We will apply eligibility criteria for review selection and assess the evidence synthesis validity of selected reviews using the most recent version of CEESAT (Collaboration for Environmental Evidence Synthesis Assessment Tool). The results will be displayed in topic subgroups in summary of scope and summary of findings tables.

A Targeted Review of Worldwide Indirect Treatment Comparison Guidelines and Best Practices

ObjectivesControls and governance over the methodology and reporting of indirect treatment comparisons (ITCs) have been introduced to minimize bias and ensure scientific credibility and transparency in healthcare decision making. The objective of this study was to highlight ITC techniques that are key to conducting objective and analytically sound analyses and to ascertain circumstantial suitability of ITCs as a source of comparative evidence for healthcare interventions. MethodsOvid MEDLINE was searched from January 2010 through August 2023 to identify publicly available ITC-related documents (ie, guidelines and best practices) in the English language. This was supplemented with hand searches of websites of various international organizations, regulatory agencies, and reimbursement agencies of Europe, North America, and Asia-Pacific. The jurisdiction-specific ITC methodology and reporting recommendations were reviewed. ResultsSixty-eight guidelines from 10 authorities worldwide were included for synthesis. Many of the included guidelines were updated within the last 5 years and commonly cited the absence of direct comparative studies as primary justification for using ITCs. Most jurisdictions favored population-adjusted or anchored ITC techniques opposed to naive comparisons. Recommendations on the reporting and presentation of these ITCs varied across authorities; however, there was some overlap among the key elements. ConclusionsGiven the challenges of conducting head-to-head randomized controlled trials, comparative data from ITCs offer valuable insights into clinical-effectiveness. As such, multiple ITC guidelines have emerged worldwide. According to the most recent versions of the guidelines, the suitability and subsequent acceptability of the ITC technique used depends on the data sources, available evidence, and magnitude of benefit/uncertainty.