Reasons For Acceptance Research Articles

COVID-19 vaccine acceptance and hesitancy among primary healthcare workers in Singapore

BackgroundFactors affecting COVID-19 vaccine acceptance and hesitancy among primary healthcare workers (HCW) remain poorly understood. This study aims to identify factors associated with vaccine acceptance and hesitancy among HCW.MethodsA multi-centre online cross-sectional survey was performed across 6 primary care clinics from May to June 2021, after completion of staff vaccination exercise. Demographics, profession, years working in healthcare, residential status, presence of chronic medical conditions, self-perceived risk of acquiring COVID-19 and previous influenza vaccination were collected. HCW who accepted vaccine were then asked to rank their top 5 reasons for vaccine acceptance; HCW who were vaccine hesitant had to complete the 15-item 5C scale on psychological antecedents of vaccination.ResultsFive hundred fifty seven out of 1182 eligible HCW responded (47.1%). Twenty nine were excluded due to contraindications. Among 528 respondents, vaccine acceptance rate was 94.9% (n = 501). There were no statistically significant differences in COVID-19 vaccine acceptance between sex, age, ethnicity, profession, number of years in healthcare, living alone, presence of chronic diseases, self-perceived risk or previous influenza vaccination. The top 3 reasons for COVID-19 vaccine acceptance ranked by 501 HCW were to protect their family and friends, protect themselves from COVID-19 and due to high risk of acquiring COVID-19 because of their jobs. HCW with suspected or confirmed COVID-19 exposure were 3.4 times more likely to rank ‘high risk at work’ as one of the top reasons for vaccine acceptance (χ2 = 41.9, p < 0.001, OR = 3.38, 95%C.I. 2.32–4.93). High mean scores of ‘Calculation’ (5.79) and low scores for ‘Constraint’ (2.85) for 5C components among vaccine hesitant HCW (n = 27) highlighted that accessibility was not a concern; HCW took time to weigh vaccine benefits and consequences.ConclusionCOVID-19 vaccine hesitancy is a minute issue among Singapore primary HCW, having achieved close to 95% acceptance rate. COVID-19 exposure risk influences vaccine acceptance; time is required for HCW to weigh benefits against the risks. Future studies can focus on settings with higher hesitancy rates, and acceptance of booster vaccinations with the emergence of delta and omicron variants.

COVID-19 Vaccine Booster Hesitancy (VBH) and Its Drivers in Algeria: National Cross-Sectional Survey-Based Study.

Due to the emergence of various highly contagious variants of SARS-CoV-2, vaccine boosters were adopted as a complementary strategy in different countries. This strategy has, however, posed another challenge for the national authorities to convince their population to receive the booster after the first challenge of COVID-19 primer dose vaccines. This study was conducted to determine COVID-19 vaccine booster acceptance and its associated factors in the general population in Algeria. Using social media platforms, an online self-administered questionnaire was distributed between 28 January and 5 March 2022 for all Algerian citizens who received COVID-19 vaccines. Overall, 787 respondents were included in this study. Among them, 51.6%, 25%, and 23.8% accepted, rejected, or were hesitant about the COVID-19 vaccine booster, respectively. However, only 13.2% declared receiving the booster dose. Additionally, while 58.2% of the respondents declared being relieved after primer vaccination, 11.4% among them declared that they regretted being vaccinated. The most common reasons for acceptance were experts’ recommendations (24.6%) and the belief that COVID-19 vaccine boosters were necessary and efficient, while rejection was mainly due to the belief that primer doses are sufficient (15.5%), or that vaccination in general is inefficient (8%). Males, older individuals, those with chronic comorbidities or a history of COVID-19 infection, non-healthcare workers, and those with low educational levels were associated with significantly higher odds for booster acceptance. Moreover, belief that booster doses were necessary and efficient, disagreeing with the notion that primer doses were not sufficient, experts’ recommendations, and the desire to travel abroad were significantly associated with higher odds of COVID-19 vaccine booster acceptance.

Knowledge, Attitude and Practices of Family Planning in Antenatal Women in a Tertiary Care Hospital during COVID-19 Pandemic: Indian Perspective

Introduction: Family Planning is an essential element of the reproductive lifespan of a woman. It modifies and has an important impact on the life of a woman because it leads to increased morbidity and mortality following unwanted pregnancies, increased rates of abortions and further maternal complications. Hence awareness and a proper knowledge of the various available contraceptive choices to the women is important to modify the current scenario. Hence this study aims at studying the knowledge of Antenatal women, their attitude and practices being followed by them with respect to contraception. Methods: A self-administered questionnaire was given to the 100 Antenatal women attending the Outpatient Department of Obstetrics and Gynecology at Grant Government Hospital, Mumbai. Results: The results of this study depicted the importance of education, residential area and effect of COVID pandemic on the further reduction in the use of contraceptive measures available. The main reasons for low acceptance of contraception included Desire of early contraception in 24%, Lack of knowledge of contraceptive methods in 23% and apprehension for side effects of the contraception in 13% of the cases. Among the 15% of the women who were unaware of the available contraceptive methods, were willing to use the barrier contraceptives and IUCD and female sterilization. Conclusion: The results highlight the importance of social awareness and education and women employment in order to increase the use of contraceptive methods available.

The Lost Social Context of Recovery Psychiatrization of a Social Process.

From being a concept questioning the core of psychiatric knowledge and practice, recovery has been adopted as a guiding vison for mental health policy and practice by different local, national, and international organizations. The aim of this article is to contextualize the different understandings of recovery and its psychiatrization through the emergence of an individualizing and de-contextualized definition which have gained a dominant position. It ends with an attempt to formulate a new definition of recovery which integrates people in their social context. Research results from various follow-up studies showing the possibility of recovery from severe mental distress have stressed the importance of societal, social and relational factors as well of the person's own agency when facing their distress and reactions from their environment. These researches were published in the 1970s and 80s; a period of struggle for liberation from colonialism, of struggle by women and black people for their civil rights, and a time of de-institutionalization of services directed toward the poor, elderly, handicapped, prisoners, and people with mental health problems. Recovery research pointed at the central role of individuals in their recovery journey and it was understood as a personal process in a social context. However, with neo-liberal political agenda, the personal role of individuals and their own responsibility for their well-being was stressed, and contextual understandings and the role of social, material and cultural changes to promote recovery faded away. Thus, during recent decades recovery has been mostly defined as an individualistic journey of changing the persons and their perception of their situation, but not of changing this situation. Contextual aspects are almost absent. The most quoted definition accepts the limits posed by an illness-based model. This kind of definition might be a reason for the wide acceptance of a phenomenon that was initially experienced as a break with the bio-medical paradigm. Recently, this dominant individualized understanding of recovery has been criticized by service users, clinicians and researchers, making possible a redefinition of recovery as a social process in material and cultural contexts.

Reasons for acceptance and refusal of early palliative care in patients included in early-phase clinical trials in a regional comprehensive cancer centre in France: protocol for a qualitative study

IntroductionA few studies have highlighted the potential synergy between early palliative care and inclusion in an early-phase clinical trial that may improve quality of life, reduce symptoms of exhaustion related...

COVID-19 vaccine hesitancy and related factors among primary healthcare workers in a district of Istanbul: a cross-sectional study from Turkey

ObjectivesThis study aimed to determine the COVID-19 risk perceptions, vaccination intentions and predictive factors of family physicians and family healthcare staff working in primary care in Üsküdar.DesignA cross-sectional study was...

From scarcity problem diagnosis to recycled water acceptance: A perceptive-axiological model (PAM) of low and high contact uses

Water scarcity is a major problem that affects a greater number of countries every year. A possible solution is using recycled water systems. However, to implement the use of recycled water, public acceptance is needed. In this study, we propose a perceptive-axiological model (PAM) to understand the reasons for public acceptance or rejection of recycled water. This is the first model to jointly consider three conceptual dimensions: the diagnosis of the environmental situation, the axiological influence and the public perceptions regarding recycled water. The sample in this study consisted of 726 randomly selected participants who completed an online questionnaire. A key factor considered was the type of water use (low- or high-contact). Additionally, the model's ability to predict acceptance in regions of high and low water stress was tested. The model showed good fit and predictive capacity for both low (R2 = .272) and high (R2 = .501) contact uses and partial equivalence between regions. Threat perception was the most distal variable in the model which, together with identity, affected the attribution of responsibility. These variables, along with trust in scientists, affected the three direct predictors of acceptance: perceived health risks, moral obligation, and cost-benefit analysis. Perceived health risk was the most important predictor in both types of contact (β = -.642 in high-contact, β = -.388 in low-contact uses). Moral obligation had a greater impact in high-contact (β = .170) than in low-contact (β = .099) uses; the opposite outcome occurred with respect to costs-benefit analysis (β = .067 in high-contact, β = .219 in low-contact uses). The PAM offers a general framework that identifies the importance of the three dimensions and how they interact with each other, which facilitates the development of strategies to increase acceptance. On the one hand, the PAM works as a tool to assess the profile of a specific population and, on the other hand, it highlights the specific factors which are the best suited for interventions to increase public acceptance.

Feasibility study on collecting patient-reported outcomes from breast cancer patients using the LINE-ePRO system.

Due to the increasing complexity of cancer treatment, ensuring safety and maintaining the quality of life during treatment are important issues. Patient‐reported outcomes (PROs) in oncology are essential for assessing patient symptoms. A feasibility study was undertaken on breast cancer patients by building a PRO data collection system based on LINE, one of the most popular social network service applications in Japan. In this study, one or more predefined PRO questions for each breast cancer patient's clinical situation were sent to the patient’s LINE application daily. The patient selected a predefined answer by tapping the screen, but no free‐text answers were allowed. Seventy‐three patients were enrolled. The median observation period was 435 days (84‐656 days), and the total number of PROs collected was 16,417, with a mean of 224.9 reports per patient. Patients on adjuvant endocrine therapy were notified of 2.5 questions per week, and the median number of responses per week and response rate were 2.387 (1.687‐11.627) and 95.5%, respectively. Analyzing the results by age group, the number of responses from those aged 60 and above was equal to or higher than that of the younger age group. It was also possible to track each patient’s PROs accurately. These results suggested that the design of the system, based on an application used daily, instead of using specifically prepared applications for collecting electronic PROs, was the reason for the favorable acceptance from patients and the satisfactory response rate from all age groups, including the elderly.

Knowledge attitudes and practices toward seasonal influenza vaccine among pregnant women during the 2018/2019 influenza season in Tunisia.

The uptake and acceptance of the influenza vaccine (IV) among pregnant women remain unknown in Tunisia despite the increased influenza-related complications and death. The present study aimed to assess the IV uptake and acceptability and to describe related knowledge and attitudes among pregnant women in Tunisia. A cross-sectional study was conducted in 84 Tunisian healthcare facilities over a period of three months (from March to May 2019). All pregnant women aged ≥18 years who sought antenatal care in related health structures were included in this study based on a multistage self-weighted sampling. We measured knowledge and attitudes towards the IV and assessed factors related to willingness for its uptake. The questionnaire was completed by 1157 pregnant women. More than half of the participants (60.2%; 95% confidence interval [CI] [57.3%-63.0%]) reported awareness about the IV. Among included PW, only 4.6%; 95% CI [3.5%-6.1%] received it during their current pregnancy. However, (36.8%; 95% CI [34.0%-39.6%]) declared their willingness to receive the vaccine in the next pregnancy. Recommendation by healthcare providers, identified to be the most trustful source of information, was the main reason for acceptance. However, the intention to accept the IV by pregnant women was significantly associated with such recommendation and perceived safety and effectiveness of this vaccine. Antenatal care visits are a precious opportunity that should not be missed by health care providers and especially gynecologists to promote the IV uptake by pregnant women in Tunisia.

Feasibility, acceptability and needs in telemedicine for palliative care.

Telemedicine in palliative care was initially developed in countries where geography or resources limit access to care services. Recently, largely owing to the COVID-19 pandemic, this technology is being increasingly used in highly urbanised countries such as Switzerland. However, there is still scepticism regarding whether these tools can be used effectively in palliative care, a relationship-based speciality that is generally highly dependent on compassion, communication and direct human interaction. The objective of this review was to analyse the needs, elements of feasibility, and reasons for acceptance or possible barriers before the implementation of a telemedicine intervention in Switzerland. The method used was a scoping review, following the PRISMA-ScR reporting guidelines. We searched the PubMed, Ovid SP, Medline, Cochrane and Scopus databases for relevant reports. Charting and analyses of the data were done by a single researcher. A total of 520 records were screened and assessed for eligibility. Finally, 27 studies and 4 registry entries were included. Main reasons for exclusion were wrong population and intervention. The prevailing study type was the single-arm intervention study. Most studies originated from countries with geographic barriers to access. Feasibility was good in 69% of all studies. Good acceptability (84.1-100%) was confirmed in the majority of the studies. The needs of the patients or the healthcare professionals were directly addressed in only five (16%) studies. Three needs were consistently reported: communication, coordination and technical reliability. Despite a broad range of studies on telemedicine in palliative care, patients' needs are rarely addressed. Therefore, especially in countries such as Switzerland, a needs assessment is recommended before the implementation of a new telemedicine intervention, to guarantee high feasibility and acceptability.

Reasons for participation and non-participation in colorectal cancer screening

ObjectivesThe aim of the present analysis is to identify the reasons for accepting or rejecting the invitation to be screened by the Faecal Immunochemical Test as part of the free Danish screening programme for colorectal cancer (CRC). Study designA cross-sectional representative survey of 15,072 Danish citizens aged 50–80 years was collected in 2019 via a Web-based questionnaire administered by Statistics Denmark. Among the net sample of 6807 respondents (45%), 177 were excluded because of current treatment for colorectal disease. MethodsTo determine the reasons for accepting or refusing the invitation to be screened for CRC, a latent class analysis was conducted, which allowed participants to provide several reasons for acceptance or rejection of screening. ResultsThe most important reason for participating in CRC screening was the active public programme. A further reason for participation was the perceived risk for CRC, mainly in combination with the public programme. The reasons for participation did not differ between individuals who had participated and those who intended to participate when offered. Among participants who declined screening, the most frequent reasons were that they forgot to participate or that they were concerned about the unpleasant test procedure. Among individuals who intended to decline screening, a perceived low risk for CRC was the most frequently cited reason. ConclusionsRecommendation from a general practitioner (GP) was not given as a frequent reason for CRC screening participation which is discussed as a challenge to participation rates in population based screening program The main reasons reported for non-participation in CRC screening (i.e. forgot to participate or the unpleasant test procedure) might be addressed by a stronger endorsement from GPs.

Polyps seen but not removed during index colonoscopy: an underestimated inefficiency in endoscopy practice

In the United Kingdom endoscopists are certified for independent practice once competent in the removal of polyps up to 20mm in size. Where polyps are detected but not removed during the index colonoscopy, a repeat procedure is required. The aim of this study was to identify the proportion of polyps<20mm that were not removed at the time of diagnosis. Polyps identified at colonoscopy during a 12-month period in a single institution were included in this study. All polyps were categorized according to the reported size and complexity per the size, morphology, site, access (SMSA) classification. In cases where polyps≤20mm were not removed, patient records and endoscopy reports were interrogated to ascertain the reasons for this. Across 1444 patients, 2442 polyps<20mm in size were diagnosed. Removal at the time of the index procedure occurred in 1158 patients (80.2%). Nonremoval for a predefined acceptable reason, such as concomitant anticoagulation therapy, accounted for 174 cases (12.0%). Nonremoval without contraindication was noted in 112 cases (7.8%). The mean polypectomy complexity as determined by the SMSA score of these polyps was lower than level 2, denoting low complexity. The requirement for unnecessary repeat procedures equated to 9.3 days of endoscopy capacity per year. This study demonstrates that a small but significant proportion of small colorectal polyps are not removed at the time of diagnosis. This practice has implications for both patients and service provision.

Sodium Valproate versus Amitriptyline in the Prophylactic Treatment of Migraine

Background: Drug prophylaxis of migraine is a safe and effective way of reducing the attack of headache frequency and the economic burden of migraine. Several drugs have been shown to be efficacious in double-blind placebo-controlled trials. Many patients avoid the regular intake of prophylactic drugs because of fear about the side effects, tolerance and addiction. Another reason for the low acceptance of migraine prophylaxis is that the efficacy of most drugs is limited and the burden of treatment cost. In this study two effective drugs, Amitriptyline and Sodium valproate are evaluated regarding their safety and efficacy. This study shows the comparative effectiveness, safety of both drugs and withdraw all the misconception about the prophylactic treatment of migraine among the patients and improve their life style adjustment and reduce the economic burden of the society.&#x0D; Objective: The purpose of the present study was to observe and compare the efficacy of Sodium Valproate and Amitriptyline in the prophylactic management of migraine patients.&#x0D; Methodology: This experimental study was carried out in the Department of Neurology at Sir Salimullah Medical College &amp; Mitford Hospital, Dhaka, Bangladesh during the period from January 2013 to December 2013. A total of 120 patients with migraine were selected of which 60 were treated with Amitriptyline (Group-A) and another 60 were treated with Sodium Volproate (Group-B). Both groups were observed for 6 months and the improvement of headache regarding frequency, severity and duration of episodes of headache was recorded in every 2 months follow up. Adverse effect of the drugs also monitored in both group.&#x0D; Result: Out of 120 patients the mean age was 32±8.64years and 34.23±8.09 in group-A and group-B respectively (p=0.147). There were 23 (38.3%) male and 37 (61.7%) female in group-A; whereas 17 (28.3%) male and 43 (71.7%) female in group-B (p=0.245). Thus the study was an age and sex matched study. It was observed that one third 20(33.3%) patients were house wife’s in group-A and 24(40.0%) in group-B. The difference was not statistically significant (p&gt;0.05) between two groups. Frequency of attack per month before treatment was 6.25±5.21 in group-A and 7.80±4.1 in group-B. Frequency of attack per month after 2 months treatment was 4.30±4.14 and 6.19±4.10 in group-A and group-B respectively. Frequency of attack per month after 4 months treatment was 3.78±2.53 in group-A and 4.89±2.83 in group-B. Frequency of attack per month after 6 months treatment was 1.70±1.42 in group-A and 3.1±1.98 in group-B. Frequency of attack per month after 2, 4 and 6 months treatment was statistically significant (p&lt;0.05) between two groups. It was observed that majority (88.3%) patients were improved headache in group-A and 23(38.3%) in group-B. The difference was statistically significant (p&lt;0.05) between two groups.&#x0D; Conclusion: The pain intensity score is significantly decline in patients who received amitriptyline after treatment and almost similar in patients who received sodium valproate. Improved headache most of the patients who received Amitriptyline and less adverse effects developed in this group. Amitriptyline is more effective, seems to be safer than Sodium Valproate.&#x0D; Journal of National Institute of Neurosciences Bangladesh, July 2021, Vol. 7, No. 2, pp. 126-131

POS-986 TWITTER AS EDUCATIONAL TOOL IN NEPHROLOGY: A GLOBAL WEB BASED CROSS-SECTIONAL STUDY ON SOCIAL MEDIA BEHAVIOUR OF NEPHROLOGISTS

Twitter is most popular social media platform among medical community. NephTwitter allows discussions on new research, exchange experiences and indulge in scientific debates with experts in respective medical fields. It helps in building professional and educational environment. With such impact of social media, expected participation in the nephrology community is less than ideal. We designed this study to determine the acceptance of Twitter among nephrologists globally to determine its impact on their clinical practice and ascertain reasons for low acceptance by nephrologists

Vaccine hesitancy among Veterans Affairs Health Care System employees

Vaccine hesitancy undermines the control of the COVID-19 pandemic and has been observed in health care workers. As part of a quality improvement effort, we aimed to describe reasons for vaccine acceptance and hesitancy among employees in the Veteran Affairs Portland Health Care System (VAPORHCS). We administered an open-ended and web-based survey to all VAPORHCS employees in July 2021. Data were analyzed using a rapid usability framework, whereby qualitative data were synthesized into thematic categories to inform decision making. Among the 1157 employees who completed the survey, 88% reported that they had received the vaccine and 12% reported that they did not receive the vaccine. Over half (54%) of vaccinated respondents reported having initial hesitancy to the COVID-19 vaccine but overcame their hesitancy by deciding that the vaccine’s benefits outweighed its risks. Reasons for COVID-19 vaccine acceptance were: 1) individual and community health; 2) protect vulnerable and unvaccinated family members; 3) promote patient and workplace safety; 4) scientific evidence. Reasons for COVID-19 vaccine hesitancy among unvaccinated employees were: 1) concerns with safety and risk profile of vaccine; 2) mistrust in vaccine development; 3) personal choice; 4) openness to future vaccination. These results provide information for tailored vaccine messaging efforts as well as emphasizes the need for trust-building between employees and health care organizations.

COVID-19 Vaccine Hesitancy in Pregnancy: A Cross-Sectional Study

Objective: As approval of one of many coronavirus disease-2019 (COVID-19) vaccines' use for pregnancy is getting closer, vaccine hesitancy may take place in pregnant individuals for this new vaccine. Our study aimed to evaluate vaccine acceptance and factors affecting vaccine acceptance in case of an approved COVID-19 vaccine for pregnant individuals. Material and Methods: Our study was designed as one group, cross-sectional, prospective study. Sample consisted of pregnant individuals who didn't have any chronic illnesses and didn't contract COVID-19 in the last 6 months. In-person style survey was used to collect data about demographics, knowledge about COVID19 disease and it's effects on pregnant individuals, vaccine acceptance and reasons for acceptance or refusal. Results were analyzed with descriptive statistics, chi-square test and Shapiro-Wilk test of normality using Number Cruncher Statistical System. Results: Among 250 participants, 183 (73.2%) reported they wouldn't accept COVID-19 vaccination if there was a safe and effective vaccine approved for use in pregnancy. Main reasons of refusal were the belief that vaccine hadn't been studied on humans enough or that it might have adverse effectes on baby and/or pregnant individual. Only factor associated with vaccine acceptance was found to be knowing someone who had severe COVID-19 disease (p=0.022). Conclusion: Our study shows that vaccine hesitancy rates may be high among pregnant individuals when a COVID-19 vaccine is approved for use in pregnancy. The main reason for vaccine hesitancy is safety concerns.

Acceptability of Micro-Insurance Scheme among Teachers in Public Secondary Schools in Lagos State, Nigeria

Low income earning workers such as the teachers in the public secondary schools, are faced with varying categories of financial risk which cannot e alleviated without the help of some other social arrangement such as micro-insurance schemes. However, these scheme has not been well accepted among the teachers. The study however, looked at the reasons for the low acceptability. A stratified simple random sampling technique was used to collect data from a sample of 384 secondary school teachers in Lagos state, using regression analysis techniques. Adequate knowledge and well structured products designs of the micro-insurance products does not influence the acceptability of the products among the teachers. The study result however, shows that not making the products compulsory is the major factor that influence the acceptability among the teachers.

Kidney Transplants from Elderly Donors: The Experience of a Reference Center in Croatia.

Our country Croatia is among the global leaders regarding deceased donation rates, yet we are facing organ shortage and concurrently a sharp decline in our acceptance rates for kidney offers. To reevaluate our organ acceptance policy, we retrospectively analyzed the factors that influenced the posttransplant outcomes of kidneys from elderly deceased donors at our center during a 20-year period and the changes to our organ acceptance criteria during Eurotransplant membership. We studied all kidney transplants from donors ≥60 years old during the two 5-year episodes of Eurotransplant membership from 2007 to 2017 (period II and period III) and compared those data to data from the decade before Eurotransplant membership (period I, 1997-2007). Differences in acceptance rates and reasons for the decline of kidney offers between the two 5-year periods of Eurotransplant membership were analyzed. In period I, 14.1% of all kidney allografts were obtained from donors ≥60 years old; in period II and period III the rates were nearly 2-fold higher (27.0% and 25.7%, respectively; P = .007 and P = .008). During the first 5-year period of Eurotransplant membership (period II), we accepted significantly more grafts from marginal donors with a higher number of human leukocyte antigen mismatches compared with period I. Consequently, the 3-month survival rate of kidneys from donors ≥60 years old dropped from 91.1% to as low as 74.2% (P = .034). After application of morestringent human leukocyte antigen matching, especially in human leukocyte antigen DR, and morestringent donor acceptance criteria in period III, graft survival improved to 91.1%. Our experience indicates that careful selection of kidneys from elderly deceased donors and allocation to human leukocyte antigen-matched recipients is important to improve transplant outcomes.

COVID-19 Vaccine-Acceptancy among Health Care Workers and General Community in a Southern City of India: Pre- and Post-arrival of Vaccines

Context: By December of 2021, 80% of the eligible Indian population had received at least one shot of COVID-19 vaccine. However, this phase of vaccination was hindered with the very prevalent vaccine hesitancy and, in its absence, India would have reached this mark of coverage much earlier. Vaccine skepticism is still present, especially around vaccination of children and it may further delay coverage in our next phase of vaccination. Methods and Material: A total of 680 healthcare workers (HCWs) and 1,308 General public (the community) were interacted with in a South Indian city between the months of December 2020 and February 2021. An online-platform based survey was conducted where vaccine acceptancy levels were studied among them before and after vaccine roll out in the country. The reasons for acceptance as well as hesitancy were surveyed. Simultaneously, vaccine awareness activity was conducted. Results: The overall vaccine acceptance among the HCWs was reflected to be 68.5% &amp; in the community it was found to be 60.4% at the time of vaccine rollout. Nearly half, i.e., 51.6% of the HCWs and 50.58% in the community, expressed the reason for hesitancy as the fear of side effects. Conclusions: Carrying out Mass-vaccination activities without adequately assessing the acceptancy levels among its beneficiaries and taking measures to allay the reasons for hesitancy will lead to delayed coverage and an ineffective vaccination drive which is an ultimate failure of purpose. Need of the hour is an effective communication &amp; health education measure that would address all the concerns related to COVID-19 vaccine

COVID-19 Vaccination Compliance and Associated Factors among Medical Students during an Early Phase of Vaccination Rollout-A Survey from Israel.

COVID-19 is “a once-in-a-century” pandemic, bringing with it unparalleled health, social, and economic ramifications. As part of the world’s efforts to restrain the pandemic, vaccine development has been expedited. This population-representative survey in Israel aimed to investigate whether the knowledge, attitudes, and vaccination status of medical students affect their intention to recommend COVID-19 vaccination (as well as reasons for refusal and acceptance of the vaccine). The questionnaire was anonymous, via Google Forms app in December 2021. One-hundred and four medical students completed the survey. Overwhelmingly, (91.3%) COVID-19 vaccination status and intention to receive the vaccine were positively associated with intention to recommend. Twenty-five percent of the students replied that they lacked knowledge regarding the vaccine. A statistically significant association was found between experiencing quarantine and the intention to be vaccinated (p = 0.034). There was a significant positive relationship between the number of symptoms from previous vaccines and the fear of COVID-19 (rs = 0.272, p < 0.01). Prior vaccination did not have an effect on COVID-19 vaccine hesitancy. This first study evaluating COVID-19 vaccine hesitancy among Israeli medical students highlighted the need for medical programs to emphasize the benefits of COVID-19 vaccination in the protection of healthcare workers and patient safety. Education, awareness campaigns, and regulation of vaccine trials could further decrease COVID-19 vaccine hesitancy and increase vaccine rates among medical students.