Reasonable Limits Research Articles

Compressive behavior of CFDST columns: Effects of thin-walled inner steel tubes

Concrete-filled double skin steel tubular columns with large hollow ratios (LHR-CFDST), as quintessential elements within offshore wind turbine structures, have received significant attention in contemporary times. As the scale of this type of structure continues to expand, an effective strategy to reduce steel consumption involves elevating the diameter-to-thickness (D/t) ratios of the steel tubes. Presently, there is a dearth of studies that explore the performance of LHR-CFDST columns in the case of thin-walled inner steel tubes. Four LHR-CFDST columns with varying D/t ratios of the inner tubes and one double-skin hollow steel tubular column were produced and tested under axial compression. The study encompassed an investigation into failure modes, local buckling behaviors, and ductility characteristics. The local buckling performance index of specimens with varying D/t ratios differed by up to 16.9%. Furthermore, the verified finite element model was subsequently employed for mechanistic analyses pertaining to the sandwiched concrete's stress distributions, and so on. When the peak loads were attained, the maximum variation in the stress values of the concrete of the specimens with different D/t ratios reached 50.4%. Subsequently, a multi-parameter impact analysis was applied to give a reasonable limit on the D/t ratio (225) of the inner steel tube for engineering design. Finally, the prevailing ultimate strength formulas outlined in established specifications were adapted by integrating the characteristics uncovered through this investigation.

Establishment of a microspheres-based homogeneous fluorescence immunoassay for the rapid detection of cardiac troponin I.

Myocardial infarction occurs rapidly, and thus the rapid detection of cTnI levels is the key to its diagnosis. Most current assays take 10-30 min. In this study, we developed a method for accurately measuring cardiac troponin I (cTnI) levels in human sera with amplified luminescence neighborhood homogeneous assay (AlphaLISA). The method involves coupling two cTnI antibodies targeting different epitopes to the surface of carboxylated donor and acceptor beads. The final signal values were detected by the double-antibody sandwich method, and the best reaction conditions were obtained by optimizing the experimental conditions. The sensitivity, specificity, accuracy, and precision of the method were evaluated. Results showed that the method requires only 3 min to produce the results, the detection sensitivity is 27.06 ng L-1, and the measurement range is 34.56-62 500 ng L-1. cTnI-AlphaLISA has an intra-assay precision of 2.18-4.57% (<10%) and an inter-assay precision of 5.60-6.95% (<10%). The relative recovery rates are within reasonable limits. In addition, the serum assay results of the method were compared with chemiluminescence immunoassay, and the results are in agreement with one another (ρ = 0.8803; P < 0.0001). The method is expected to be developed as a routine method, but further studies and evaluations are needed.

Toxicity of Oils Extracted From the Arils of Blighia sapida (K.D. Koenig) in Wistar Rats.

Blighia sapida oil, a substance with a rich history of use for its nutritional, therapeutic, traditional, and cosmetic benefits, was the focus of our study. We investigated the impact of consuming edible oil from B. sapida arils on Wistar rats. The crude oil from unripe arils was extracted using cold pressing and then administered to the rats. The toxicity was evaluated according to the OECD method. Notably, there were no signs of food poisoning or adverse effects on the weight and behavior of the rats treated with B. sapida oils. The LD50 of the oil was more significant than 5000 mg/kg of body weight, and hematological and biochemical parameters did not differ significantly from the control group. Rats fed with an oil-supplemented diet showed an increase in weight compared to the negative control group. No fatty deposits were found in vital organs, and consuming the oil did not affect the immune system or biochemical biomarkers. However, excessive intake of fat may have harmful effects on tissues. Our findings strongly suggest that B. sapida oil is safe for consumption within reasonable limits. The data we present here reveal that the oil derived from B. sapida is suitable for moderate consumption and may offer various health advantages, a potential that warrants further exploration.

Enzyme-linked immunoassay for simultaneous detection of methyl parathion and sibutramine in apple cider vinegar.

Methyl parathion, a highly toxic, efficient, and persistent organophosphorus pesticide, is widely used in China. Sibutramine, a non-amphetamine central nervous system depressant, helps lose weight by disrupting hormone regulation, stimulating sympathetic nerves, and suppressing appetite. However, some unethical businesses fail to properly handle raw materials in foods like apple cider vinegar, leading to residual methyl parathion in apples or illegal excessive addition of sibutramine. Therefore, it is imperative to develop an immunoassay for the rapid detection of methyl parathion and sibutramine. The corresponding two haptens were prepared and coupled with the carrier proteins according to methyl parathion-sulfur-bovine serum protein (BSA)/chicken ovalbumin (OVA)-sibutramine (20 : 1 : excess, 15 : 1 : excess, 10 : 1 : excess, and 5 : 1 : excess), and sibutramine-BSA/OVA-methyl parathion (20 : 1 : excess, 10 : 1 : excess: 5 : 1 : excess, and 0 : 1 : excess). The result shows that the inhibition rate of the antibody obtained by methyl parathion-BSA/OVA-sibutramine (20 : 1 : excess) was higher than that of sibutramine-BSA/OVA-methyl parathion, which was 67.93%, and the concentration of methyl parathion was 8.65 ng mL-1 at this inhibition rate. Thus, methyl parathion-BSA/OVA-sibutramine (8.65 : 1 : excess) and the corresponding antibodies were selected for subsequent method establishment. By changing the concentration of the coating and antibody, the inhibition rate was found when the coating was 0.125 ng mL-1 and the antibody was diluted 4000 times. The antibody was used to develop a standard curve for the detection of sibutramine at the half-maximum inhibitory concentration (IC50) is 4.59 ng mL-1, the limit of detection (IC10) is 2.21 ng mL-1, the detection range is 2.89 to 7.28 ng mL-1, methyl p-phosphorus at the half-maximum inhibitory concentration (IC50) is 15.34 ng mL-1, the limit of detection (IC10) is 0.42 ng mL-1, the detection range is ng mL-1. Under these conditions, the recovery rate was between 88% and 102%, within reasonable limits, indicating the successful establishment of a rapid enzyme-linked ELISA assay.

Разумный срок судебного разбирательства по уголовному делу

The analysis of the concept of a reasonable timeframe for court proceedings is a pressing issue in the current stage of the development of criminal procedure in Russia. Several international mechanisms for protecting individual rights in the sphere of criminal proceedings, including those for contesting reasonable timeframes, have been lost. The study employed general and specific scientific methods, such as dialectical, axiological, and synergetic approaches, as well as the theory of social action and modeling. Moreover, the application of methods of analysis and synthesis of information, comparative legal analysis, and formal legal approaches allowed the author to reach reliable conclusions. The research established that failure to adhere to reasonable timeframes for judicial decision-making violates the rights of individuals involved in criminal proceedings. Ensuring the protection of individuals’ rights and legitimate interests is only possible when reasonable time limits in criminal procedure are observed. Based on the provisions related to compensation for violations of the principle of reasonable timeframes during court proceedings, a conclusion was drawn regarding the essence of these provisions, which allows for an evaluation of the criteria of reasonableness outlined by the legislator and the identification of methods for their assessment.

Phronesis (Practical Wisdom) and Philia (Friendship)

In Aristotle’s ethics, friendship is a complex and nuanced construct, which he termed philia. Aristotle’s philia is much broader than affinity­‑based peer relationships, as friendship is often conceived currently. He identified three types of friendship (utility, pleasure, and character), and he devoted approximately 20% of the Nicomachean Ethics to friendship. This is because close personal relationships and developing oneself as a character friend are extremely important to living well as a human. This centrality makes character or virtue friendship distinctive and highly valuable. We apply the construct of phronesis to philia to reveal important aspects of both. First, we argue that situations common to character friendships highlight the reasonable limits of the emotion regulation function of phronesis in resolving seemingly intractable ethical conflicts. Second, we suggest that these limits suggest, counterintuitively, that character friendships (even among the most virtuous actors) are still subject, under some conditions, to substantial feelings of conflict and emotional ambivalence.

Reconciliation in John Winthrop's History of New England

Abstract: The prominence of dissent and the reconciliation of dissent in John Winthrop's History of New England serves as a useful reminder that Massachusetts was not as monolithic as is often thought and that colony's ability to cope with differences of religious opinion was important to the way it represented itself. Instance of reconciliation in the History also have a face-saving effect in that they cast the colonial government as a reasonable and patient judge of permissible versus intolerable dissent while, at the same time, casting irreconcilable difference as unreasonable and self-interested, and therefore punishable. This essay studies how reconciliation events in the History work rhetorically to validate the colonial government's power both by displaying its capacity for tolerance and by defining the reasonable limits of what is tolerable.

ВЗЫСКАНИЕ УБЫТКОВ ЗА НАРУШЕНИЯ, ДОПУЩЕННЫЕ СУДЕБНЫМ ПРИСТАВОМ‐ИСПОЛНИТЕЛЕМ НА СТАДИИ ИСПОЛНИТЕЛЬНОГО ПРОИЗВОДСТВА

the author examines the issues of recovery of damages for violations committed by a bailiff at the stage of enforcement proceedings in courts of general jurisdiction. Based on the analysis of current judicial practice, the author concludes that a systematic interpretation of the norms of substantive law, explanations of the Supreme Court of the Russian Federation and judicial practice of cassation and appeal courts of general jurisdiction allows us to conclude that the claim for damages from the bailiff will be refused if the bailiff proves the absence of his guilt namely, that he has taken all necessary and sufficient measures within reasonable limits to ensure the legality of actions to execute the executive document, including to exclude the possibility of harm to third parties.

Transformation of the model of the design scheme of the power system in the problem of ensuring balance reliability

The paper deals with the issues reducing the number of territorial zones in the model calculation scheme UPS of Russia as applied to the problem of substantiating the required generating capacity (capacity reserve) under the conditions of ensuring normative indicators of balance reliability in accordance with the requirements of the new guidelines for design of power systems. On the example of the model UPS of Russia calculation scheme developed by SO UPS specialists, the possibilities of reducing the number of territorial zones to reasonable limits are shown.

Labor law and artificial intelligence: points of contact and differences

The advent of high-tech and self-learning AI algorithms is setting off an unprecedented transformation of social production processes that will fundamentally affect the entire world of labor. According to the author, the introduction of AI into the world of labor will undoubtedly lead to a temporary surge in technological unemployment, but in the long term, new technologies will create more jobs in new sectors of the economy. The impact of AI on unemployment is context-specific and should be subject to government regulation. The author points out that as a result of the introduction of AI algorithms in the world of labor, arise not only the traditional problems of strengthening the economic power of the employer, discrimination or unauthorized collection of personal data, but set a big complex of legal problems related to the responsibility of the employer for decisions that he himself cannot control. Therefore, for labor law, the most important task is to eliminate the discrepancies between the current model of legal regulation of labor relations and the risks of introducing AI into decision-making processes of hiring and controlling employees. The science of labor law should develop relevant approaches to a reasonable limitation of the use of AI, taking into account the peculiarities of modern algorithmic technologies, production prospects, legal and social risks. The author criticizes proposals for endowing AI with legal personality and the possibility of delegating responsibility for the implementation of employer functions to algorithms. According to the author, AI cannot have legal personality in labor relations (as well as in legal relations of any other type), since the functioning of AI is carried out through the datification of all their participants without the goal of achieving a socially significant result and establishing interaction between subjects of law regarding the satisfaction of their needs. AI is a means of automating labor processes, a digital interface for interaction between elements of the production system. The author states that AI in legal reality can exist only as an object of law. The author proposes to fix in the labor legislation the presumption of responsibility of the employer for the decisions made by AI, regardless of the originally programmed algorithms, even if they were changed by AI as a result of machine learning.

An Integrated Autonomous Dynamic Navigation Approach toward a Composite Air-Ground Risk Construction Scenario.

Unmanned transportation in construction scenarios presents a significant challenge due to the presence of complex dynamic on-ground obstacles and potential airborne falling objects. Consequently, the typical methodology for composite air-ground risk avoidance in construction scenarios holds enormous importance. In this paper, an integrated potential-field-based risk assessment approach is proposed to evaluate the threat severity of the environmental obstacles. Meanwhile, the self-adaptive dynamic window approach is suggested to manage the real-time motion planning solution for air-ground risks. By designing the multi-objective velocity sample window, we constrain the vehicle's speed planning instructions within reasonable limits. Combined with a hierarchical decision-making mechanism, this approach achieves effective obstacle avoidance with multiple drive modes. Simulation results demonstrate that, in comparison with the traditional dynamic window approach, the proposed method offers enhanced stability and efficiency in risk avoidance, underlining its notable safety and effectiveness.

Parameters optimum of multiple underframe suspended equipment on high-speed railway vehicle carbody vibration control by using an improved genetic algorithm

Carbody vibration control and ride comfort improvement are important research parts of high-speed railway vehicle dynamic. The effectiveness of utilizing carbody underframe suspended equipment as dynamic vibration absorbers for carbody vibration suppression has been validated. While previous research has focused mainly on a single suspended equipment without considering its vibration tolerance, a balance must be struck between reducing carbody vibration and maintaining equipment performance. To address the challenging, a multi-objective and multi-parameter optimization method is employed, integrating an improved niche genetic algorithm (INGA) into the numerical simulation process. Considering carbody flexible and multi-suspended equipment, a rigid-flexible dynamics model of a high-speed railway vehicle is established and validated on a vehicle dynamics test rig. Based on the numerical analysis, the optimal parameter combination of the stiffness and the longitudinal installation position is obtained from an evaluation function that comprehensively assesses the vibration performance of both the vehicle carbody and the equipment. Comparative analysis between the results obtained from the optimal and primitive parameters demonstrates that the optimization process not only achieves significant improvements in carbody vibration reduction but also effectively controls equipment vibration within reasonable limits. The multi-objective and multi-parameter optimization method applied on carbody underframe suspended system proves to be valuable in improving the dynamic performance of high-speed railway vehicles.

Analysis Of The Impact Of The Shopee Application On Students' Wasteous Behavior

Currently, many people are using e-commerce. As devout Muslims adhere to Islamic law, every individual should use e-commerce applications wisely and avoid extravagance. Extravagance is spending wealth excessively on unnecessary purposes or exceeding the limits of reasonableness in shopping. Islam always teaches its followers not to be excessive (extravagant) and advocates for simplicity. The purpose of this study is to determine whether students have avoided extravagance in shopping on e-commerce platforms. The method employed in this research is descriptive research and field study. The respondents in this study consist of 30 students from Muhammadiyah University of Yogyakarta. In this research, 86% of the respondents are still exhibiting extravagant behavior, primarily due to their inability to control their finances and their preference to shop according to their desires. There are 14% of respondents who have managed to avoid extravagance, mainly because they can manage their finances well and only shop for necessities by reducing their desires, thus restraining themselves in controlling their shopping behavior

Digital technologies and human rights: challenges and opportunities

Digitalization has revolutionized modern life, but it also presents complex challenges to human rights. The objective of this study is to consider digital technologies phenomenon in its complexity. In our research we mainly relied on dialectical method, systematic approach, comparative-historical method, axiological approach. Our research highlights both a range of benefits and a variety of risks associated with the deployment of digital technologies into life. Key concerns include data safety, human consciousness manipulations, cyber-security threats, the 'digital divide', algorithmic biases, and authoritarian technology misuse. But despite these challenges, digitalization offers opportunities for human rights advancement. We can also envision comprehensive social inclusion in cyberspace, digital literacy promotion, further technological innovation, and robust ethical and legal frameworks safeguarding digital rights. Mindful AI deployment can enhance living standards, improve education and healthcare, and even extend longevity. Contemporary political systems must comprehend and regulate digital technology's power, ensuring responsible governance, as without safety protocols and reasonable limitations for AI-powered tools and technologies, human rights and freedoms remain at risk.

Nested column generation for split pickup vehicle routing problem with time windows and time-dependent demand

This study attempts to solve a split pickup vehicle routing problem with time windows and time-dependent demand. This is a vehicle routing problem in which demand is generated at different constant rates for different customers, and vehicles are allowed to pick up demand during the demand generation process. In this problem, the pickup time determines the quantity of demand that can be picked up, and a partial pickup is permitted during a single visit. The problem is formulated into a mixed-integer nonlinear programming model, and a sequence-extended network is designed to represent the relationship between multiple pickups. Because of the interdependences of time, load, and cost in the pricing subproblem, the classic labelling algorithm with weak dominance rules is ineffective, therefore, a nested column generation-based branch-and-price-and-cut algorithm is proposed to tackle the problem. The nested structure allows these trade-offs to be resolved in a lower-level column generation, and it can be applied to other interdependent routing problems. The computational results show that the proposed algorithm is effective in obtaining optimal solutions for small- and medium-scale instances within a reasonable time limit.

The Renewed Christocentric Synthesis in Joseph Ratzinger’s Logos-centric Symphony

This article aims to present Joseph Razinger’s Christocentric approach to the question of the relation between faith and reason. Modernity introduces the separation between faith and reason, which results in the limitation of reason and the subordination of logos to ethos. This disunity, however, between faith and reason and the primacy of the ethos over logos affects the nature and mission of theology. In contrast to the loss of the integrative harmony between faith and reason, Joseph Ratzinger argues for the distinction and unity between faith and reason built upon the primacy of logos and a Christocentric approach. The author also intends to prove that although Ratzinger describes his theology as “fragmentary” and “incomplete,” he has gifted the Church with a renewed theological symphony that flourishes only in conjunction with the gift of faith working in concert with reason. In Ratzinger’s view only faith can enable reason to overcome the self-imposed limitation developed by modern thinkers such as Immanuel Kant. Finally, the article will demonstrate that the crowning achievement of Joseph Ratzinger/Benedict XVI’s theology is the recognition of the primacy of love as embodied by the saints who are witnesses of the transformative power of knowing and loving Jesus, the Incarnate Logos.

Enhanced sensitivity and selectivity of an electrochemical sensor for real-time propofol monitoring in anesthesia

In this study, an electrochemical sensor for the real-time monitoring of propofol (PPF) in anesthesia was developed using molecularly imprinted polymers and reduced graphene oxide-modified glassy carbon electrodes (MIPs/rGO/GCE). To make the electrode, GO was thermally reduced into rGO, which was then electrodeposited on GCE (rGO/GCE), followed by the electropolymerization of MIPs using LiClO4, pyrrole, and PPF (template) solution on rGO/GCE (MIPs/rGO/GCE). The PPF was then taken out of the pyrrole polymer. X-ray Diffraction (XRD), Scanning Electron Microscopy (SEM), and X-ray Photoelectron Spectroscopy (XPS) examinations of surface composition and morphology revealed that electropolymerization MIP on rGO/GCE and reduction and deposition of rGO on GCE were both successful processes. MIPs/rGO/GCE revealed significant sensitivity and selectivity towards PPF in electrochemical tests utilizing cyclic voltammetry (CV) and amperometry. Results demonstrated a linear range from 0.5 to 250 μM that was steady and wide, with a sensitivity of 1.0776 μA/μM and a detection limit value of 0.08 μM. MIPs/rGO/GCE demonstrated outstanding electrocatalytic activity over a broad linear range and a reasonable detection limit value for PPF concentrations. To assess the method's applicability for the analysis of PPF, it was applied to real biological samples of human plasma and urine.

Faith and reason in the unity of truth in the thought of st. Thomas Aquinas and John Paul II

Both St. Thomas Aquinas and St. John Paul II regarded man’s pursuit of truth as his vocation. He encouraged a bold trust in the use of reason in theology and a clear awareness of the limitations of reason. The fact that reason cannot prove faith does not render it powerless; on the contrary, Thomas provides evidence for unwavering confidence in the capacity of the believing reason. The call to seek faith and reason in unity with truth is not easy, as culture has seen deficiencies and errors regarding the truth about man, his faith, and the possibilities of knowledge that reach down to the very foundation. There is a continuous need to rediscover the meaning and purpose of human life and its values, through the belief in the possibility of truth attained through reason and through reasonable faith. Following in the footsteps of Thomas, John Paul II, in his encyclical Fides et Ratio, aims to inspire human love for the embrace of truth, which is not purely a theoretical goal but is essential for guiding one’s life. The purpose of this article is to highlight various difficulties and solutions in the search for coherence between faith and reason and briefly signal the necessity of prior knowledge and application of metaphysical and anthropological theology. To achieve this goal, the thoughts of Saint Thomas, whose work constitutes a fundamental part of the Church’s teaching, are presented, and for the reinforcement of Thomistic arguments, the content of Pope John Paul II’s contemporary encyclical Fides et Ratio is utilized, which points to the writings of Thomas as helpful in the maturation of human knowledge toward full human wisdom. Another important message of the article is a better understanding of the issues discussed, which, when reinterpreted and from the abundance of content, appropriately justified, can regain their lost power. The structure of the article facilitates the analysis of the presented issue in the context of understanding integral anthropology.

Overwhelming Complexities: Between Rome and Jerusalem

Abstract In the search for an understanding of the complexities that could have led such a “banal” man as Adolf Eichmann, to stand trial in Jerusalem for crimes against Humanity – in the humanity of the Jewish People – one ought to go beneath the surface of contemporary events into the roots of an overwhelming hatred that enslaved Europe for far too long and with consequences beyond what imagination could have conceived within the limits of reason alone. In the pursuit for the “black hole” that brought European nations to a virtual ethical collapse, seriously damaging the capacity to exercise judgment, this article approaches one of the background dimensions of anti-Semitism which enabled the actions of men to structure evil in all but a “banal” manner. The second part of this study seeks alternative ways to conceive a relation between Judaism and Christianity.

Is the Party Really Over? Parties, Partisanship and the Politics of Crime

Abstract Political parties occupy a contradictory position in the criminological literature: at once active participants in the political contestation of crime but virtually absent from contemporary debates concerning the relationship between crime and democratic theory. In this paper, I present a ‘rational reconstruction’ of party and partisanship as distinctive modes of political association that are vital to liberal democratic systems that take seriously (1) the value of political pluralism and (2) the limits of public reason to yield definitive answers to the crime question. Currently, political parties are failing to perform these mediating roles satisfactorily and I conclude that a stronger normative commitment to an ‘ethic of partisanship’ can help to revitalize our representative democracies and foster a better politics of crime.