Abstract The aim of this paper regards the laboratory validation of an energy management system (EMS) for an industrial site on the Eigerøy island (Norway). It will be the demonstration district in the ROBINSON project for a consequent concept replication. This activity in cyber-physical mode is an innovative approach to finalize the EMS tool with real measurement data with prime movers available at laboratory level, considering the necessary EMS robustness and flexibility for replication on other industrial islands. This EMS was designed and developed to minimize variable costs, producing on/off and set-point signals that, through a model predictive control (MPC) software, establish the system status. This smart grid includes renewable sources (e.g., solar panels, a wind turbine, and syngas) and traditional prime movers, such as a steam boiler for the industry needs. Moreover, an energy storage device is installed composed of an electrolyzer with a hydrogen pressure vessel. The main results reported in this work regard 26-h tests performed in cyber-physical mode thanks to the real-time interaction of hardware and software. So, a real microturbine and real photovoltaic (PV) panels were managed by the EMS in conjunction with software models for components not physically present in the laboratory. Although the optimization target was cost minimization, significant improvement was also obtained in terms of efficiency increase and CO2 emission decrease.