Lattice structures, characterized by their repetitive, interlocking patterns, provide an efficient balance of strength, flexibility, and reduced weight, making them essential in fields such as aerospace and automotive engineering. These structures use minimal material while effectively distributing stress, providing high resilience, energy absorption, and impact resistance. Composed of unit cells, lattice structures are highly customizable, from simple 2D honeycomb designs to complex 3D TPMS forms, and they adapt well to additive manufacturing, which minimizes material waste and production costs. In compression tests, lattice structures maintain stiffness even when filled with powder, suggesting minimal effect from the filler material. This paper shows the principles of creating finite element simulations with 3D-printed specimens and with usage of the lattice structure. The comparing of simulation and real testing is also shown in this research. The efficiency in material and energy use underscores the ecological and economic benefits of lattice-based designs, positioning them as a sustainable choice across multiple industries. This research analyzes three selected structures—solid material, pure latices structure, and boxed lattice structure with internal powder. The experimental findings reveal that the simulation error is less than 8% compared to the real measurement. This error is caused by the simplified material model, which is considering the isotropic behavior of the used material PA12GB (not the anisotropic model). The used and analyzed production method was multi jet fusion.