ABSTRACT Due to climatic changes, the probability of occurrence and the intensity of extreme weather events increase day by day which leads to power outages. The probability of failure events is calculated using Monte Carlo simulation technique which is used to identify the most frequent failure events. The least eigenvalues of the inverse reduced Jacobian matrix decide the sensitive buses for load shedding using V-Q sensitivity analysis. This work presents the multi-objective differential evolution (MODE) algorithm for solving resilient constrained optimal power flow (RCOPF) in a deregulated power system. The control variables namely the real power of generators in a base case and under event, generator bus voltage magnitude, the real and reactive power demand of the selected load buses, tap settings and capacitor bank ratings. This algorithm is validated in IEEE 30 bus test system and the Indian 62 bus utility test system to show the effectiveness in four different cases including tie lines and distributed generation.