This study explores the effectiveness of reading promotion activities in university libraries with the help of new media. Taking Chongqing C Vocational College as an example, through the study of the relationship between College Students' reading motivation and reading self-efficacy, we can understand the real reading needs and help carry out reading activities. 311 students were selected by purposive sampling for formal questionnaire distribution. 272 valid questionnaires were obtained, and the effective recovery rate was 88%. The SPSS26.0 statistical software was used for item analysis, confirmatory factor analysis, reliability and validity analysis, linear regression analysis and other methods to analyze and verify the data of the effective questionnaire. The research results are as follows: The personal cultivation motivation of Chongqing C College students has a significant positive impact on their reading self-efficacy. The emotional expression engine and reading self-efficacy of Chongqing C College students have a significant positive impact. The motivation for information acquisition and reading self-efficacy of Chongqing C College students have a significant positive impact. The social interaction motivation and reading self-efficacy of Chongqing C College students have a significant positive impact. The motivation for reading interest and self-efficacy of college students at Chongqing C College have a significant positive impact.