In this article, a convolutional neural network (CNN)-based electronic nose system is proposed, which utilizes time series features to classify the freshness of food. The electronic nose is composed of three elements: a highly sensitive miniaturized micro-electromechanical systems (MEMS) metal–oxide (MOX)–semiconductor gas sensor array, a complementary metal–oxide–semiconductor (CMOS) integrated circuit, and a CNN-based classification unit. The gas sensors exhibit exceptional sensitivity, low power consumption, and a small size. The interface circuit for sensor readout is fabricated using a standard 180-nm CMOS process, with an area of <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$1.5\times1.5$ </tex-math></inline-formula> mm. The interface chip mainly consists of an analog-to-digital converter (ADC), an electrically erasable programmable read-only memory (EEPROM), an oscillator (OSC), power management, a heater driver, and a digital control circuit. Fixed <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${R}{(}{t}{)}$ </tex-math></inline-formula> exposures are taken at specific intervals under gas input and output conditions. Time series features are extracted from a diverse set of sensor signals, which allows the subtle differences in various food odors at different freshness levels to be identified. The incorporation of time series feature extraction extends the data features, resulting in enhanced classification accuracy with a limited number of sensors. An abstract odor map input to the CNN is formed by combining the steady-state and transient information of the gas sensor response. The final freshness classification accuracy of 20 types of foods is 97.3%. The accuracy is improved by 6.5% after the implementation of time series feature extraction, demonstrating the significance of instantaneous fluctuation information for classification accuracy.