Reaction Of Hydroxide Ion Research Articles

Hydrolysis of acylchymotrypsins

The hydrolysis rate constant for acylchymotrypsins correlates with the rate constant for reaction of hydroxide ion with the ethyl esters (slope = 0·64, r= 0·867) over a wide range of structure variation in the acyl group. The low sensitivity to change of acyl group and to change in σ for benzoylchymotrypsins (ρ= 1·55, r= 0·952) is suggested to be due to electrophilic participation at the carbonyl oxygen of the acyl group. Tosylchymotrypsin is suggested as a model for the tetrahedral adduct of 4-methylbenzoylchymotrypsin with water and the electrophiles are identified as the NH groups of gly-193, asp-194, and ser-195 peptide bonds.

The H− acidity function for dimethylformamide–water

The H− acidity function has been determined for N,N-dimethylformamide–water mixtures containing tetramethylammonium hydroxide by the Hammett indicator method. Basicity in the aqueous dimethylformamide system exceeds that in aqueous tetramethylenesulfone but is slightly less than in aqueous dimethylsulfoxide, at equivalent molar compositions of solvent and base. However, the basic aqueous dimethylformamide solvent system is only of limited utility as a result of reaction of hydroxide ion with the dimethylformamide.

Arrhenius parameters for the alkaline hydrolysis of glycine ethyl ester, in aqueous solution, and thermodynamic functions for its ionisation as an acid

The kinetics of the alkaline hydrolysis of glycine ethyl ester have been studied in aqueous solution over a wide range of pH at 0, 25, 35·5, 41·95, and 49·45°. Corrections have been made to account for protonation of the reactant ester and the product, glycine. The effect of ionic strength on the reaction rate is discussed. The results are consistent with a reaction scheme which involves two simultaneous second-order reactions of hydroxide ion with the non-protonated and protonated forms of the ester. Rate constants describing these two reactions have been found from the composite observed rate constant at all temperatures, and corresponding Arrhenius parameters are reported. Surprisingly, the reaction of the protonated ester seems to have the lower activation energy. The equilibrium constant for the ionisation of the ester as an acid has been studied as a function of ionic strength, and of temperature. Values of ΔG°, ΔH°, and ΔS° for this ionisation are reported.

Nucleophilic Reactivity. Part 9. Kinetics of the Reactions of Hydroxide Ion and Water with Picrylic Compounds.

Nucleophilic Reactivity. Part 9. Kinetics of the Reactions of Hydroxide Ion and Water with Picrylic Compounds.

Nucleophilic Reactivity. Part 7. Kinetics of the Reactions of Hydroxide Ion with 1-Substituted 2,4-Dinitrobenzenes in Water.

Nucleophilic Reactivity. Part 7. Kinetics of the Reactions of Hydroxide Ion with 1-Substituted 2,4-Dinitrobenzenes in Water.

A Study of the Reaction of Hydroxide Ion with B20H18-2

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Study of the Reaction of Hydroxide Ion with B20H18-2M. Frederick Hawthorne, Richard L. Philling, and Philip M. GarrettCite this: J. Am. Chem. Soc. 1965, 87, 21, 4740–4746Publication Date (Print):November 1, 1965Publication History Published online1 May 2002Published inissue 1 November 1965https://doi.org/10.1021/ja00949a013RIGHTS & PERMISSIONSArticle Views86Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (807 KB) Get e-Alerts Get e-Alerts

THE MECHANISM OF BASE HYDROLYSIS AND BASE CATALYZED REACTIONS OF SOME COBALT(III) AMMINE COMPLEXES

S>Two mechanisms, direct displacement and conjugate base dissociation, were previously proposed for the reaction of hydroxide ions with complexes of cobalt (III) containing a replaceable liquid. S ome results were obtained which were easily explained by the second or conjugate base dissociation mechanism which could not be explained by the first. (M.C.G.)

The Diacetone Alcohol—Hydroxide Ion Reaction from the Standpoint of Ion-Dipole Theory

The Diacetone Alcohol—Hydroxide Ion Reaction from the Standpoint of Ion-Dipole Theory