The COVID-19 pandemic had an impact on all spheres of public health. The multiplied load on medical organizations, forced use of unsuitable premises for treatment of people could not but affect disinfection activities. In addition, given the closed borders in 2020, there was a shortage of both raw materials and ready disinfectants on the market. On the one hand, this situation has led to an explosive interest of the business community in the disinfectants market. This is evidenced by the increased number of disinfectants registered in the Russian Federation from 164 in 2019 to 467 and 471 in 2020 and 2021, respectively. In this study, we analyzed technical specifications for the procurement of disinfectants by medical organizations posted on www.zakupki.gov.ru. Despite the fact that during the period there were relaxations in the procurement legislation that allowed medical organizations to directly purchase disinfectants from suppliers, the analysis revealed significant deviations in 2020 and 2021 in the consumption of disinfectants compared to 2017–2019 and 2022. For example, the consumption of disinfectants based on sodium hypochlorite increased significantly. Also, with the shortage and increased cost of alcohol-based skin antiseptics, purchases of soaps with antibacterial properties have increased, which is especially noticeable in 2021. However, the 2022 purchases indicate that healthcare organizations are returning to normal operations and their consumption of disinfectants is becoming similar to that seen in 2017–2019. Keywords: disinfectants, auctions, hospital-acquired infection.