964 The purpose of this study was to examine neuromuscular activation and ratings of perceived exertion (RPE) at 10% and 80% quadriceps MVC in healthy males. 17 college-aged volunteers (mean age = 22.6 years, mean height = 178.9 cms, mean weight = 78.8 kg) were assessed for isometric EMG activity of the vastus medialis (VM) and vastus lateralis (VL) at 10% and 80% MVC, and RPE at 80% MVC. Perceived exertion was measured with a modified category ratio scale(CR-10). 10% and 80% MVC's were performed with the knee at 60 deg of flexion for 5 s. Raw EMG signals were sampled via telemetry (rate = 1000 Hz) and integrated (IEMG, 3 s) for each contraction and muscle (bandpass = 16-500 Hz, CMRR = 130 dB). A one-sample t-test was performed for each variable and 95% confidence intervals (CI) were calculated. The mean and CI for each variable are as follows: 10% MVC VM IEMG (t16 = 5.05, p<0.001,.95 CI = 3.11± 1.3), 80% MVC VM IEMG (t16 = 22.51, p<0.001,.95 CI = 73.2± 6.89), 10% MVC VL IEMG (t16 = 8.10, p<0.001,.95 CI = 9.41± 2.47), 80% MVC VL IEMG (t16 = 39.56, p<0.001,.95 CI = 87.32± 4.68), and 80% MVC RPE (t16 = 11.85, p<0.001,.95 CI = 5.24± 0.93). The results demonstrated that at 10% and 80% MVC, VM activation is lower than torque output. VL activation appears to correspond with torque output at 10% MVC but is higher at 80% MVC. RPE appeared to be underestimated in the quadriceps at 80% MVC. Alterations in vastii muscle recruitment at various intensities may have a significant impact on RPE during isolated muscle contractions.