Rational Therapy Research Articles

UNDERSTANDING THE AYURVEDIC CONCEPT OF CHITTODVEGA IN THE CONTEXT OF GENERALIZED ANXIETY DISORDER AND ITS MANAGEMENT THROUGH AYURVEDA

Generalised anxiety disorder is among the most common mental health conditions. Up to 20% of people are af-fected by anxiety problems each year. An ongoing feeling of overwhelm, fear, and concern are signs of general-ised anxiety disorder. Generalised anxiety disorder is characterised by excessive, irrational, and persistent worry about everyday issues. This worry may have several aspects, including financial, family, health, and future con-cerns. Most people with GAD also have additional mental diseases, such as panic disorder, social anxiety disor-der, significant depression, or particular phobia. Generalised anxiety disorder can affect both adults and children. The sickness often begins in infancy or adolescence but can begin at any age. GAD is twice as common in women and those assigned female at birth as it is in men and those assigned male at birth. Charaka stated the Manasavikara (mental disorder) Chittodvega (anxiety), which is said to be the ideal word to highlight the state of anxiety, namely generalised anxiety disorder. Both as a distinct illness and as a contributing component to other psychological and psychosomatic disorders, Chittodvega can occur. According to clinical investigations, anxiolytic medications by themselves have limited long-term effectiveness, and serious side effects such as se-dation, drug dependency, and resistance cannot be avoided. Ayurveda takes a psychosocial approach to medi-cine. Acharya Charaka describes three forms of treatment for mental and physical illnesses: Satwavajaya Chikitsa (Psychotherapy), Yuktivyapashraya (Rational therapy), and Daivavyapashraya (Spiritual therapy). Apart from these, we can also treat mental illness through counselling. Thus, the current study examines Chittodvega from the Ayurvedic classics and how to handle it.

Investigation and Treatment of Infertility in a Female Black Rhinoceros (Diceros bicornis).

A zoo-based, 11-year-old, uniparous southern black rhinoceros (Diceros bicornis minor) failed to conceive after weaning a calf. Behavioral observation and fecal progestagen monitoring confirmed irregular estrous cycles. Serial transrectal reproductive ultrasound examination revealed the cause to be recurrent anovulatory hemorrhagic follicles (AHFs). After four consecutive abnormal cycles dominated by AHFs, rational hormone therapy was implemented. Injectable prostaglandins, progesterone, estradiol, and a GnRH analog were given strategically to disrupt AHFs, boost normal estrus behavior, and promote ovulation. Oxytocin was added to the treatment regimen when transient accumulations of intraluminal uterine fluid consistent with endometritis were observed ultrasonographically. Oral diazepam was given judiciously for anxiolysis after the animal developed an aversion to injection. Treatment, which proceeded over eight cycles, was eventually associated with the restoration of normal behavioral estrus and ovulation. The rhinoceros conceived after natural mating and induced ovulation, delivering a healthy calf 490 days later, the longest reported gestation for the species.

Integrating Rational Emotive Behavior Therapy, Compassion-Focused Therapy with Cognitive Retraining in Traumatic Brain Injury: A Case Report

Integrating Rational Emotive Behavior Therapy, Compassion-Focused Therapy with Cognitive Retraining in Traumatic Brain Injury: A Case Report

IMPLEMENTATION RATIONAL EMOTIVE BEHAVIOR THERAPY (REBT) APPROACH IN IMPROVING PSYCHOLOGICAL RESILIENCE OF ADOLESCENTS: A Literature Review In Guidance And Counseling Education

The purpose of this study was to examine in more depth the effectiveness of the REBT approach in improving adolescent resilience through an analysis of relevant literature. The research method used was a literature review by analyzing articles, books, and journals that were relevant to the relationship between the Rational Emotive Behavior Therapy (REBT) approach and resilience skills. Based on the literature review, it was found that REBT is not only effective in improving adolescent resilience, but can also increase self-esteem and reduce anxiety, two factors that are closely related to resilience. Previous studies have shown that by intervening in irrational beliefs, REBT can strengthen adolescents' ability to deal with stress and difficulties, thereby improving their mental well-being.

Acute rhinosinusitis in children in outpatient practice: The possibilities of rational therapy and prevention of complications

Acute rhinosinusitis in children in outpatient practice: The possibilities of rational therapy and prevention of complications

Effectiveness of Rational Emotive Behavior Therapy on Level of Stress and Anxiety among Sober Alcohol Dependents Attending Self Help Groups in Selected Areas

ABSTRACT Introduction: Stress and anxiety are common, especially in challenging situations. Rational Emotive Behavior Therapy (REBT) helps manage these by addressing irrational thoughts. It is also effective in reducing emotional distress linked to alcohol addiction. Methodology: This study evaluates the levels of stress and anxiety among sober alcohol dependents attending self-help groups and assesses the effectiveness of Rational Emotive Behavior Therapy (REBT) in reducing these levels. A quantitative, quasi-experimental non-randomized control group design was used, with 60 participants (30 in the control group and 30 in the experimental group) selected through convenience sampling. Conducted over 28 days, the research setting included selected self-help groups. Reliability scores for the stress and anxiety assessment tools were high (0.99) based on the test-retest method, ensuring the study's credibility. A pilot study confirmed feasibility for larger-scale research. The findings provide key insights into REBT's role in improving mental health among sober alcohol dependents. Result: The study demonstrated that Rational Emotive Behavior Therapy (REBT) is significantly effective in reducing both stress and anxiety among sober alcohol dependents attending self-help groups. For stress, pretest results in the experimental group showed 43.3% of participants had moderate stress and 56.7% had high stress. Posttest results revealed substantial improvement, with 33.3% reporting low stress and 66.7% reporting moderate stress. The paired t-test showed a significant reduction in stress scores, with an average decrease from 26.8 to 16.6 (p-value < 0.05). Similarly, anxiety levels improved significantly. In the experimental group, pretest anxiety results showed 56.7% with moderate anxiety, which dropped to 13.3% posttest. The paired t-test revealed a significant decrease in anxiety scores from 26 to 15.3 (p-value < 0.05). Comparison between experimental and control groups also confirmed the significant impact of REBT on reducing both stress and anxiety levels. Conclusion: The findings suggest that REBT is a highly effective intervention for managing stress and anxiety in sober alcohol dependents.

The effects of continuous care utilizing rational emotive therapy on prostate cancer patients

AbstractThis study is to investigate the impact of rational emotive behaviour therapy in conjunction with continuity nursing on the negative emotions and quality of life of patients with radical prostatectomy (RPT). A total of 82 patients who underwent RPT for prostate cancer and were admitted to our department between November 2020 and October 2021 were randomly divided into two groups: the control group received conventional nursing interventions, while the observation group received rational emotion therapy combined with continuity of care interventions. The patients' negative emotions and quality of life in the two groups were compared. The Self‐rating Anxiety Scale (SAS) and Self‐assessment Scale of Depression (SDS) scores of the observation group after nursing care were significantly lower than those of the control group (p < 0.01). Furthermore, the scores of the observation group in the dimensions of vitality (VT), physiological functioning (PF), general health (GH), affective functioning (RE), mental health (MH), and social functioning (SF) were higher than those of the control group (p < 0.05). Finally, the differences in both scores were statistically significant (p < 0.05). The combination of rational emotion therapy and continuity nursing has been demonstrated to have a positive effect on prostate cancer patients. It has been shown to effectively relieve patients' negative emotions, such as depression and anxiety, and to improve the quality of survival. This approach is worthy of further promotion and application in clinical practice.

Pathogenetic relationship of microbiome and metabolic disorders on the background of hypertension and gout: Potential targets of pharmacotherapy

Cardiometabolic diseases are one of the urgent problems of modern medicine. Currently, much attention is being paid to the study of the common pathogenesis of diabetes mellitus, gout and hypertension. One of the pharmacological targets is the correction of the intestinal microbiome and dysbiosis, as an integral link in the development of systemic inflammation and endotoxinemia, leading to the development of these pathologies. The article presents the results of scientific research devoted to the study of the effect of the intestinal microbiome on the development of cardiometabolic diseases. The main goal of the research is to find a rational pharmacological therapy of intestinal dysbiosis for the treatment of comorbid patients. It has been proved that, together with standard drug therapy, taking into account the pathogenetic features of the development of cardiometabolic diseases, it is advisable to use drugs that affect the intestinal microbiome. The main classical approach is the use of probiotic drugs containing live bacteria. The use of probiotics in combination with probiotic drugs to support the growth of intestinal normoflora has become a promising direction. However, this approach requires a long period of correction of the microflora, which prompted the idea of using postbiotics – signaling molecules – products of the vital activity of the microflora for a more targeted and rapid effect on pathological processes, both in the intestine and on the organ system as a whole. This approach promotes the beginning of the development of synbiotics, a complex of microorganisms, growth factors and metabolites that made it possible to more effectively influence on dysbiotic processes in various pathologies, including dyslipidemia and cardiovascular diseases. Correction of intestinal barrier permeability disorders will help prevent the development of systemic complications associated with chronic pathologies. The article also presents the author’s scheme of the pathogenesis of cardiometabolic diseases, based on the study of current scientific research.

Evaluating the impact of rational emotive behavior therapy on post-traumatic stress in farmers with experiences of natural disaster.

This study was necessary due to the increasing number of cases of natural disasters such as flood, air pollution, erosion, etc in Nigeria, particularly in the Abia state, as well as the accompanying psychological and health issues affecting individuals within families and society as a whole. The study aimed to examine the impact of rational emotive behavior therapy on farmers' post-traumatic stress (PTS) in Abia State, Nigeria. A randomized control trial was conducted in Abia state, with a sample size of 118 farmers with experiences of natural disasters. Two assessments were conducted before the treatment, immediately after the treatment, and 2 months later to evaluate PTS and irrational beliefs among the farmers. The treatment involved a self-developed PTS-focused rational emotive behavior therapy manual, consisting of 12 sessions lasting 60 minutes each, delivered by counseling psychologists trained in rational emotive behavior and family therapies. Data from the pretest, posttest, and follow-up test were analyzed using chi-square, percentage, partial eta squared, and analysis of covariance statistical tools. The results showed no significant gender differences in the socioeconomic status, employment, and debt status of the participants. The rational emotive behavior therapy was effective in reducing PTS caused by the flood among farmers. Gender did not have a significant moderating effect on farmers' experiences with PTS. The study suggested that family health specialists and rational-emotive therapists collaborate with local authorities to provide career counseling services to farmers and establish community-based rational emotive institutes in each state of Nigeria.

Asthmatic status in pediatric practice in patients with mild bronchial asthma

The main principle of the treatment of bronchial asthma is rational basic therapy, with priority appointment of inhaled glucocorticosteroids. The basis of the effectiveness of treatment is determined by the correct choice of the form of drug delivery, training the patient in inhalation skills and constant monitoring of the correct use of the inhaler. The article demonstrates the clinical observation of the formation of asthmatic status in a child with mild bronchial asthma. The deterioration of the condition and severe exacerbation was caused by insufficient intake of basic therapy funds into the respiratory tract due to improper inhalation techniques due to the patient's lack of skills in using an inhaler. At the same time, the patient was not trained and the necessary control over the correctness of the inhalation technique was not carried out at the outpatient stage.

Exploration of drug therapy related problems in a general medicine ward of a tertiary care hospital of Eastern Nepal

BackgroundInpatients are at higher risk of Drug Therapy Related Problems (DTRPs), and early identification and management of these DTRPs is crucial for optimal treatment outcomes and ensuring rational drug therapy. ObjectiveThis study aims to assess DTRPs in a general medicine ward of a tertiary care hospital in eastern Nepal. MethodsA three-month prospective observational study was conducted on inpatients admitted to the general medicine ward of the hospital. Pharmacists routinely performed patient drug therapy reviews, by which suspected DTRPs were identified and recorded as per the Pharmaceutical Care Network Europe Association (PCNE) v.9.1 guidelines. Binary logistic regression analysis was used to determine the influence of predictor variables on the occurrence of DTRPs. ResultsA total of 301 inpatients were enrolled, out of which 233 (77.4%) had one or more DTRPs. Altogether, 528 DTRPs with an average of 2.27 ± 0.92 DTRPs per patient were identified. The primary causes of the DTRPs were drug selection (40.47%), treatment duration (16.71%), dispensing (15.75%), and dose selection (13.12%). Antimicrobials were involved in 55.18% of the DTRPs. DTRPs were more prevalent in elderly, comorbid patients, patients with longer hospital stay days, and polypharmacy, which was statistically significant (p<0.05). Furthermore, multivariate binary logistic regression analysis showed that geriatric patients had a higher risk of experiencing DTRPs, with an adjusted odds ratio of 1.832 (1.021-3.286) at p-value < 0.05. ConclusionDTRPs are frequently prevalent in hospital wards, emphasizing the crucial role of clinical pharmacists in identifying, resolving, and preventing DTRPs in inpatient settings for optimal treatment outcomes.

Acute respiratory viral infections: Consensus on rational therapy

There are diseases for which people turn to specific specialists, but there are also a number of ones that are treated by doctors of different specialties. Therapists, infectious disease specialists, otolaryngologists, and pulmonologists diagnose and treat acute respiratory viral infections. But the same specialists often have to deal with the outcomes of an acute process – postnasal drip and post-infectious cough, which decreases the quality of life and exhaust patients. However, in case when the correct diagnosis is made, there are treatment regimens that allow to achieve quick relieve subjective and objective symptoms, as well as clinical cure of the disease escaping the use of antibacterial therapy. The efficient therapy agreement of the otolaryngologist and pulmonologist is that for various causes of cough, herbal medicine is the best choice.

Potential Nephroprotective Effect of uPA against Ischemia/Reperfusion-Induced Acute Kidney Injury in αMUPA Mice and HEK-293 Cells.

Background/Objectives: The incidence of acute kidney injury (AKI) has been steadily increasing. Despite its high prevalence, there is no pathogenetically rational therapy for AKI. This deficiency stems from the poor understanding of the pathogenesis of AKI. Renal ischemia/hypoxia is one of the leading causes of clinical AKI. This study investigates whether αMUPA mice, overexpressing the urokinase plasminogen activator (uPA) gene are protected against ischemic AKI, thus unraveling a potential renal damage treatment target. Methods: We utilized an in vivo model of I/R-induced AKI in αMUPA mice and in vitro experiments of uPA-treated HEK-293 cells. We evaluated renal injury markers, histological changes, mRNA expression of inflammatory, apoptotic, and autophagy markers, as compared with wild-type animals. Results: the αMUPA mice exhibited less renal injury post-AKI, as was evident by lower SCr, BUN, and renal NGAL and KIM-1 along attenuated adverse histological alterations. Notably, the αMUPA mice exhibited decreased levels pro-inflammatory, fibrotic, apoptotic, and autophagy markers like TGF-β, IL-6, STAT3, IKB, MAPK, Caspase-3, and LC3. By contrast, ACE-2, p-eNOS, and PGC1α were higher in the kidneys of the αMUPA mice. In vitro results of the uPA-treated HEK-293 cells mirrored the in vivo findings. Conclusions: These results indicate that uPA modulates key pathways involved in AKI, offering potential therapeutic targets for mitigating renal damage.

Evaluating the Impact of a Rebt-Based Suicide Prevention Program for Individuals with Alcohol Use Disorders

The purpose of this study was to evaluate the effectiveness of a suicide prevention program based on Rational Emotive Behavior Therapy (REBT) for individuals with Alcohol Use Disorder. Theoretical Framework: The study is grounded in the Rational Emotive Behavior Therapy (REBT) framework, which aims to reduce irrational beliefs, one of the root causes of emotional disturbances, including depression and suicidal ideation. Methods: A nonequivalent quasi-experimental design was employed, involving participants from two Addiction Management Integrated Support Centers in K Province, South Korea. Forty-eight individuals were divided into two groups: 24 in the experimental group and 24 in the control group, each assigned to a different center. The experimental group underwent 10 REBT sessions over 5 weeks, in addition to standard interventions. The control group received only the usual interventions. Outcome variables measured included irrational beliefs, depression, suicidal ideation, and problem-solving ability. Data were collected at baseline and again five weeks after the program ended. Statistical analyses were conducted using chi-square, Fisher's exact test, and independent t-tests. Results: Prior to the intervention, no significant differences in demographic characteristics or baseline outcome variables were observed between the two groups. After the intervention, the experimental group exhibited a significant reduction in irrational beliefs (t=2.36, p=.023), depression (t=3.80, p&lt;.001), and suicidal ideation (t=4.59, p&lt;.001) compared to the control group. Additionally, the experimental group demonstrated a significant improvement in problem-solving ability (t=4.59, p&lt;.001). Discussion/Implications: The study demonstrates that the REBT-based suicide prevention program was effective in reducing irrational beliefs, depression, and suicidal ideation, while also enhancing problem-solving ability in individuals with Alcohol Use Disorder. These results underscore the potential benefits of integrating cognitive-behavioral approaches like REBT into suicide prevention programs for this population. Originality/Value: This research contributes to the limited literature on suicide prevention programs tailored for individuals with Alcohol Use Disorder and offers valuable insights into the applicability of REBT in community-based mental health interventions. The findings suggest the importance of developing structured therapeutic programs that address both cognitive distortions and emotional well-being to prevent suicide in vulnerable populations.

The effectiveness of rational emotive behavior therapy and acceptance and commitment therapy on oxidative stress in patients with hypertension

The effectiveness of rational emotive behavior therapy and acceptance and commitment therapy on oxidative stress in patients with hypertension

Clinical Decision Support Systems to Identify Drug-Related Problems in Diabetes Mellitus Patients: A Systematic Review

Clinical Decision Support Systems (CDSSs) has been developed for utilization to provide rational therapy to Diabetes Mellitus (DM) patients including preventing Drug-related Problems (DRPs) such as the effect of drug treatment being not optimal, untreated indications and symptoms, unnecessary therapy, and adverse drug reactions. This study aims to summarize the available evidence on the intervention of CDSSs, key outputs, and impact of the user in DM patients. This study was a systematic review using PubMed, Scopus database, and by manually searching the bibliographies of articles that have been found. We included studies reporting on evaluated CDSSs that had been implemented in medication prescription, reducing medication errors, adverse drug events, drug-allergy checking, drug dosing support, and so on. A total of 8 studies were selected among 855 studies. CDSSs are used in hospitals and primary care settings to identify potential drug interactions, correct therapy regimens, monitor therapy, blood glucose documentation, ensure patients receive medication according to the guideline, provide nutritional advice, and schedule physical activity. The usage of CDSSs improves blood glucose levels, detects possible drug interactions, reduces face-to-face consultations, improves documentation, assists in identifying dose, and promotes prescribing in line with the guideline. The use of CDSSs can help to reduce the risk of errors in management therapy.

The Effect of Rational Emotive Behavior Therapy (REBT) Intervention on Reducing Anxiety and Improving the Quality of Self-Coping of Pregnant Women in the Working Area of the Nilam Sari Community Health Center, Bukittinggi City 2015

One indicator of the success of health services is reflected in the decline in maternal mortality. but in reality in Indonesia it is still relatively high. One of the factors that affect the health of pregnant women is excessive anxiety. The result of various studies in the world show, excessive anxiety in pregnancy adversely affect the quality of pregnancy and can lead to complications, mental health development of children. This study aims, know the effect of interventions Rational Emotive Behavior Therapy (REBT) to decrease anxiety and quality of coping pregnant women in the region Puskesmas Nilam Sari Bukittinggi 2015. The method used in this study is Quasy Experiment design non randomized pretest – post test without control with a sample of 16 pregnant women categories moderate to very hight anxiety. Measuring Instruments used quesionnaires Pregnancy Anxiety Scale (PSA), Pregnancy Related Anxiety Scale (PRAS), Revised Ways Of Coping Scale (WCQR), and an Intervention Module designed practicing with psychologist regarding principle of step Rational Emotive Behavior Therapy (REBT). Analysis of data using Friedman test, Wilcoxon and Marginal Homogeneity test.

Psychological Dynamics among Adolescents with Self-Harm Behavior Based on Rational Emotive Behavior Therapy

The objective of this study was to ascertain the psychological underpinnings of self-harm behaviors among adolescents, with a particular emphasis on the tenets of rational emotive behavior therapy (REBT). Additionally, this study aimed to elucidate the various forms of self-harm behaviors and the underlying factors that contribute to these behaviors in adolescents. This research employed a qualitative approach with a phenomenological research design. The research subjects were students at State Senior High School 1 Batu, Indonesia, selected based on certain criteria in accordance with the research needs (purposive sampling). The results demonstrate three key aspects of the psychological dynamics of adolescents with self-harm behavior, namely cognitive, affective, and conative. These were mapped into the ABC model, which comprises three elements, namely activating events, irrational beliefs, and impacts. Forms of self-harm in adolescents include physical (slashing the hand) and non-physical (ignoring health, smoking, taking drugs, and staying up late). The background of adolescents committing self-harm behavior is influenced by both internal factors (dissatisfaction and loneliness) and external factors (family problems and modeling).

Intervenții psihologice în diminuarea singurătății la vârstnici: eficacitatea programului formativ

In the context of an aging population, loneliness among the elderly has emerged as a major public health concern, with significant negative effects on both mental and physical health. Older adults frequently face post-retirement stress, depression due to the loss of loved ones, and anxiety driven by material and health-related uncertainties. These factors not only exacerbate chronic psychological disorders but also contribute to increased social isolation and a decline in quality of life. The literature highlights a significant correlation between loneliness, socio-demographic variables, and various negative emotional states, such as anxiety, depression, and stress, while also underscoring the considerable impact on personality and quality of life. This study presents a psychological intervention program designed to reduce loneliness among the elderly, based on a multidimensional approach that integrates cognitive-behavioral techniques, rational-emotive therapy, reminiscence therapy, and art therapy. The program was tested on a sample of 24 elderly individuals, randomly assigned to experimental and control groups. The results, obtained through a comparative experimental design, demonstrate a significant reduction in depression, anxiety, and stress among participants in the intervention group, emphasizing the importance of implementing such programs to improve the quality of life for the elderly.

The effect of rational therapy on modifying irrational thoughts among university students

The current research aims to identify the effect of the thinking distraction method in reducing existential frustration among university students at the College of Physical Education and Sports Sciences/Al-Qasim Green University. The researcher has dealt with a theoretical framework that includes all the variables of the research, and to achieve the goal of the research, an existential frustration scale was built, using a statistical analysis sample. The number of items in this scale was (200) and after verifying its validity and reliability, the number of items in this scale reached (30) distributed across the scale’s areas. To test the research hypotheses, the researcher chose a sample of (14) male students only, who were intentionally selected from those who obtained the highest scores on the scale. Existential frustration scale: They were divided into two groups (experimental and control) with (7) students in each group. After parity was achieved for the two groups. As well as building the therapeutic program according to the problems posed in the scale according to the method (the thinking-distraction method), one session of the therapeutic program was taken, and after completing the application of the therapeutic program using the group therapy method on the research sample, the results showed that the program was effective in reducing existential frustration among university students.