Our aim was to asses the feasability and potential complications of endovascular intervention for the management of early hepatic artery thrombosis (HAT) at the first post operative day after living-donor liver transplantation. A retrospective review of 668 recipients who underwent LDLT between August 2001 and august 2016 at 3 centers. Endovascular interventions were performed using standard catheter techniques. Thrombolysis was performed using tPA or streptokinase, whereas angioplasty and stent placement were performed if there was an underlying stricture. Early HAT within 2 weeks postoperatively occurred in 30 patients (4.5%). Endovascular interventions were performed for 26 patients with initial success in 22/26 (84.6%) and failure in 4/26 (15.4%). Rebound thrombosis developed in 4/22(18.2%). Complications occurred in 8/26 (30.7%): bleeding (4/26), anastomotic rupture (1/26), and dissection (3/26). The overall definite endovascular treatment sucess rate of HAT was 18/26 (69.2%), whereas that of definite surgical/endovascular or combined treatment was 26/30(86.6%). HAT occurred on the first postoperative day in 8/30 patients. Endovascular intervention was attempted in 4 patients and succeeded in 3 patients (75%). Surgery was attempted in 4 patients and succeeded in 3 patients (75%). Endovascular complications occurred in 2/4 patients (50%)؛ bleeding occurred in 1 patient, and anastomotic rupture occurred in 1 patient. Endovascular intervention for the mangement of HAT in the first postoperative day after LDLT carries a considerable risk of potential complications related to the technique and thrombolytic therapy. However, it is feasible and can be attempted for graft salvage if surgery is considered futile.