Oxygen electrode delamination is the key degradation mechanism of reversible solid oxide cells (rSOC) operating in the electrolysis mode. Previous experimental studies have shown that rSOC operating in fuel cell mode can mitigate this degradation and extend its lifetime. As a result, this paper proposes a multiscale degradation model that integrates microscale structures, mesoscale parameters, and macroscale performances to investigate the sensitivity of the alleviation of oxygen electrode delamination to reverse operating conditions. After that, the model is validated by available experimental data at the microscale and macroscale. Subsequently, the multiscale degradation behaviors regarding certain operating conditions are discussed. The analysis demonstrates that, on the one hand, the cell degradation is mainly attributed to lanthanum zirconate oxide (LZO) formation during long-term operation; on the other hand, the higher the temperature and current density, the faster the degradation. Consequently, a new parameter of LZO layer thickness related to oxygen electrode delamination is introduced to assess the sensitivities of durability improvement to reverse operating variables, namely starting switch moment, operating duration, and operating temperature. Meanwhile, voltage degradation rate and hydrogen production are also evaluated. The result indicates that a decrease in the starting switch moment and an increase in the operating duration can reduce the growth of LZO layer thickness and prolong the incubation time for oxygen electrode delamination. It can also decrease the degradation rate and hydrogen production. However, improving reverse operating temperature reduces the LZO layer thickness growth rate and degradation rate without affecting hydrogen production.