Rare Earth Mixtures Research Articles

Risk on assessment of 15 REEs and mixtures by DGT in Songhua River system sediments of China's largest old industrial base

Rare earth elements (REEs) are increasingly used in the high-tech sectors in the world and are therefore called burgeoning contaminants. As diffusive gradients in thin films (DGT) can be used to assess the bioavailability of inorganic matters, in this paper, we evaluated, for the first time, the ecotoxicology risks of REEs and their mixtures in river sediments of China's old industrial base by DGT. During our research, taking the Songhua River system (SRS) as an example, we detected its surficial sediments, of which the DGT-labile concentration of REEs (∑REEs) was 2.07–8.76 μg/L. As for the single toxicity, the risk quotient (RQ) values of Y at all sites were significantly greater than 1; while the values of Nd and Pr in some upstream reaches were all significantly greater than the threshold (1), indicating that these adverse effects of single REEs were not neglected. In terms of the combined toxicity of REEs mixtures, we carried out an assessment of the risks of probabilistic ecotoxicology, which showed that the SRS superficial sediments had a low probability of toxicity to aquatic organisms (0.54%).

Extraction of a target element from a mixture of rare earth elements in a single-stage process

The generally accepted method for extracting the required element from a mixture of rare earth elements (REE) is to use two cascades, with elements with a higher ordinal number being separated in one cascade, and those with a lower ordinal number in the second cascade (or vice versa). The features of the extraction and separation of rare-earth and associated elements in ores (actinium, yttrium) by extraction with mixtures of cation-exchange and anion-exchange extractants are considered. For the indicated extractants, the dependences of the REE distribution coefficients on the atomic number are opposite. Therefore, a change in the composition of mixtures of these extractants makes it possible to regulate their extraction ability and selectivity of the extraction of elements in a wide range. It is shown that the selection of the composition of the mixtures makes it possible to create conditions under which the required element is extracted worse than the others, and it can be isolated in a single-stage extraction process. In this case, the greater the separation coefficients of neighboring REEs during extraction with each of the extractants, the higher the separation selectivity. For the successful isolation of the required element from a mixture of lanthanides within the framework of one extraction cascade, the separation coefficients between neighboring elements during extraction with individual extractants must be at least 3.0. For some elements (yttrium, actinium), there is a shift in the position of an element in the REE series in terms of distribution co efficients, which consists in the fact that during extraction with one extractant, the distribution coefficient of this element is closer to lanthanum, and with the other extractant, closer to lutetium. It is shown that in this case it becomes possible to separate such an element (for example, yttrium) within one cascade, and the separation coefficients between neighboring elements can be much lower. The separation selectivity increases with the shift of the selected element in the series of lanthanides (according to the distribution coefficients): the greater the shift of the isolated element, the higher the separation factor of the isolated element from the rest of the REEs. Using one extraction cascade instead of two significantly reduces production costs.

Separation of Rare-Earth Elements from Nitrate Solutions by Solvent Extraction Using Mixtures of Methyltri-n-octylammonium Nitrate and Tri-n-butyl Phosphate.

The article presents data on the solvent extraction separation of rare-earth elements (REEs), such as La(III), Ce(III), Pr(III), and Nd(III), using synergic mixtures of methyltrioctylammonium nitrate (TOMANO3) with tri-n-butyl phosphate (TBP) from weakly acidic nitrate solutions. Specifically, experimental results on separation of REEs, for the pair Ce(III)/Pr(III) for quaternary mixtures of REEs (La(III), Ce(III), Pr(III), Nd(III)) and for the pair La(III)/Pr(III) for solutions containing La(III), Pr(III), and Nd(III), are presented. It was shown that effective separation for the pair Ce(III)/Pr(III) from a solution containing 219 g Ce(III)/L, 106 g La(III)/L, 20 g Pr(III)/L, 55 g Nd(III)/L, and 0.1 mol/L HNO3, was achieved using 56 steps of a multistage, counter-current solvent extraction cascade with scrubbing, at an organic-to-aqueous phase volume ratio (O/A) equal to 2/1 on the extraction section and O/A equal to 4/1 on the scrubbing section, using 3.3 mol/L solutions of the mixture TOMANO3-TBP with molar ratio 0.15:0.85 in dodecane. Separation for the pair La(III)/Pr(III) could be achieved using a solvent extraction cascade with scrubbing in 32 steps at O/A equal to 2/1 on the extraction section and O/A equal to 2.8/1 on the scrubbing section of the solvent extraction cascade from a solution containing 258 g La(III)/L, 58 g Pr(III)/L, 141 g Nd(III)/L, and 0.1 mol/L HNO3 with 3.0 mol/L solution of the mixture TOMANO3-TBP with molar ratio 0.2:0.8 in dodecane.

Early Pregnancy Exposure to Rare Earth Elements and Risk of Gestational Diabetes Mellitus: A Nested Case-Control Study.

ObjectiveThe extensive use of rare earth elements (REEs) in many technologies was found to have effects on human health, but the association between early pregnancy exposure to REEs and gestational diabetes mellitus (GDM) is still unknown.MethodsThis nested case-control study involved 200 pregnant women with GDM and 200 healthy pregnant women from the Peking University Birth Cohort in Tongzhou. We examined the serum concentrations of 14 REEs during early pregnancy and analyzed their associations with the risk of GDM.ResultsWhen the elements were considered individually in the logistic regression model, no significant associations were found between REEs and GDM, after adjusting for confounding variables (P > 0.05). In weighted quantile sum (WQS) regression, each quartile decrease in the mixture index for REEs resulted in a 1.67-fold (95% CI: 1.12-2.49) increased risk of GDM. Neodymium (Nd), Praseodymium (Pr), and Lanthanum (La) were the most important contributors in the mixture.ConclusionThe study findings indicated that early pregnancy exposure to lower levels of REE mixture was associated with an increased risk of GDM, and Nd, Pr, and La exhibited the strongest effects in the mixture.

Evaluation of effective parameters on the non-aqueous solvent extraction of samarium and gadolinium to n-dodecane/D2EHPA

In this study, the non-aqueous solvent extraction is used for the extraction of samarium and gadolinium ions. The aqueous phase comprises ethylene glycol (+1 M LiCl) and metal ions. The various extractants such as D2EHPA, Cyanex272, TOPO, Alamine336 was employed in n-dodecane as a less polar organic phase. The effect of various parameters was investigated on extraction, such as solvent type, extractant type and amount of phase ratio, pH, and temperature. The results showed that D2EHPA extractant diluted in n-dodecane with a concentration of 0.05 M could reach the desirability of extraction efficiency (higher than 89.5%). The optimal concentrations of nitric acid in the stripping stage for gadolinium, and samarium ions were obtained equal to 2 M and 1 M, respectively. The results showed that other rare earth elements (Y(III), and Dy(III)) could be extracted in this system with the non-aqueous system. Therefore, these systems in the leaching process for the extraction of the mixture of rare earth elements and their separation is recommended.

Lanthanum and cerium disrupt similar biological pathways and interact synergistically in Triticum aestivum as revealed by metabolomic profiling and quantitative modeling

The industrial and agricultural applications of rare earth elements (REEs) lead to considerable REE emissions into environment. Yet, little is known about the molecular-level effects and interactions of REEs in terrestrial plants. Herein, the individual and joint effects of La and Ce in Triticum aestivum were investigated using mass spectrometry-based metabolomics. Metabolic effect level index (MELI) was utilized as a readable endpoint for quantifying mixture interactions. Exposure to single La/Ce at environmentally relevant levels induced significant dose-dependent metabolic changes. The highly overlap of differential metabolites and perturbed pathways of La and Ce suggested their similar mode of action. Exposure to La-Ce mixtures did not induce additional metabolic pathway perturbation. Specifically, metabolism of amino sugar and nucleotide sugar, starch and sucrose, fructose and mannose, glycerophospholipid and purine were disrupted for both single and binary exposures. These results, together with physiological indicators, point to REE-induced oxidative stress, energy expenditure, DNA damage and membrane disturbance. The MELI calculations showed that La and Ce interacted synergistically at the overall metabolic level, which could be causally linked to synergistic interaction at the individual level (root elongation). This work proved metabolomics could be an important and effective strategy for interpreting toxicity and interactions of REE mixtures.

Structural and chemical properties of superconducting rare-earth barium copper oxide/BaHfO3 nanocomposites with rare-earth mixtures

Structural and chemical properties of superconducting rare-earth barium copper oxide/BaHfO₃ nanocomposites with rare-earth mixtures

Mixtures of rare earth elements show antagonistic interactions in Chlamydomonas reinhardtii

In order to better understand the environmental risks of the rare earth elements (REEs), it is necessary to determine their fate and biological effects under environmentally relevant conditions (e.g. at low concentrations, REE mixtures). Here, the unicellular freshwater microalga, Chlamydomonas reinhardtii, was exposed for 2h to one of three soluble REEs (Ce, Tm, Y) salts at 0.5μM or to an equimolar mixture of these REEs. RNA sequencing revealed common biological effects among the REEs. Known functions of the differentially expressed genes support effects of REEs on protein processing in the endoplasmic reticulum, phosphate transport and the homeostasis of Fe and Ca. The only stress response detected was related to protein misfolding in the endoplasmic reticulum. When the REEs were applied as a mixture, antagonistic effects were overwhelmingly observed with transcriptomic results suggesting that the REEs were initially competing with each other for bio-uptake. Metal biouptake results were consistent with this interpretation. These results suggest that the approach of government agencies to regulate the REEs using biological effects data from single metal exposures may be a largely conservative approach.

Study of lanthanum-didymium separation by solvent extraction from a liquor conditioned with lactic acid

Rare earth elements (REE) have increased in importance in the world due to the diverse applications in high-tech industries. The fact that Brazil has the world’s second largest REE reserves makes it a potential producer of these elements. However, for that to occur, it is necessary to have knowledge about the production technologies of rare earths, mainly the technologies used in the refining stages, in which China predominates. Generally, the leached solution contains a mixture of REE and the main challenge is to improve selectivity during their separation and purification. For this reason, techniques to improve the efficiency of the separation of these elements have been widely studied in recent years. In the present study, we seek to define efficient routes for the separation of lanthanum (La) from didymium (Pr and Nd) by the solvent extraction technique (SX), using the organophosphorus extractant 2-ethylhexylphosphonic acid mono-2-ethylhexyl ester (P507) from a liquor conditioned with lactic acid. Isotherms were constructed using the McCabe-Thiele method to estimate the number of theoretical stages and the aqueous/organic ratio (A/O) necessary to achieve efficient separation during the process. In continuous solvent extraction experiments, REE recovery percentages and purity of didymium and lanthanum above 90% were obtained. Didymium with 99.9% purity was obtained in a circuit with nine extraction stages (extraction A/O ratio of 4:1) and seven scrubbing stages (scrubbing A/O ratio of 2:1). The results presented here show that the use of lactic acid can be a promising alternative to boost the efficiency of the solvent extraction process for the separation of these light rare earth elements.

Dynamic interaction processes of rare earth metal mixtures in terrestrial organisms interpreted by toxicokinetic and toxicodynamic model

Despite the progress in explanation of mixture toxicity of rare earth elements (REEs), a large knowledge gap still exists in interpreting their mixed effects from a dynamic perspective. Here, we investigated the effects of La-Ce mixtures in Enchytraeus crypticus at different exposure times. The single and mixture toxicity of La and Ce increased with time, as reflected by the reduced LC50/MT50 values. With concentration addition as the reference model, the interactions between La and Ce were quantified by MIXTOX modelling tool, showing a time-dependent pattern with antagonistic effect after 1 and 2 d but additive effects afterwards. The dynamic accumulation and toxicity of La/Ce in organisms exposed to REE mixtures was fitted using a process-based toxicokinetic and toxicodynamic (TK-TD) model to unravel how the elements interacted. Generally, the estimated uptake, elimination, and damage rate constants of La/Ce declined with increasing level of each other, suggesting inhibited uptake and subsequently reduced toxicity of La/Ce due to competition effect. The interplay of La and Ce in TK and TD processes seemed responsible for the observed antagonism. Our study showed that mixture toxicity and interaction of REEs are time-dependent processes and application of TK-TD model may provide more insight into this dynamic effect.

Effect of the dose on the toxicokinetics of a quaternary mixture of rare earth elements administered to rats

Large human biomonitoring studies are starting to assess exposure to rare earth elements (REEs). Yet, there is a paucity of data on the toxicokinetics of these substances to help interpret biomonitoring data. The objective of the study was to document the effect of the administered dose on the toxicokinetics of REEs. Male Sprague-Dawley rats were injected intravenously with 0.3, 1 or 10 mg/kg body weight (bw) of praseodynium chloride (PrCl3), cerium chloride (CeCl3), neodymium chloride (NdCl3) and yttrium chloride (YCl3) administered together as a mixture. Serial blood samples were withdrawn up to 72 h following injection, and urine and feces were collected at predefined time intervals up to 7 days post-dosing. The REEs were measured by Inductively Coupled Plasma Mass Spectrometry (ICP-MS). For a given REE dose, the time courses in blood, urine and feces were similar for all four REEs. However, the REE dose administered significantly impacted their kinetics, as lower cumulative excretion in urine and feces was associated with higher REE doses. The fraction of REE remaining in rat tissues at the terminal necropsy on post-dosing day 7 also increased with the dose administered, most notably in the lungs and spleen at the 10 mg/kg bw dose. The toxicokinetic parameters calculated from the blood concentration-time profiles further showed significant increases in the mean residence time (MRTIV) for all four REEs at the 10 mg/kg bw dose. The shift in the REE kinetics at high dose may be explained by a higher retention in lysosomes, the main organelle responsible for accumulation of these REEs in different tissues.

A Novel Multi-Ionophore Approach for Potentiometric Analysis of Lanthanide Mixtures

This work aims to discuss quantification of rare earth metals in a complex mixture using the novel multi-ionophore approach based on potentiometric sensor arrays. Three compounds previously tested as extracting agents in reprocessing of spent nuclear fuel were applied as ionophores in polyvinyl chloride (PVC)-plasticized membranes of potentiometric sensors. Seven types of sensors containing these ionophores were prepared and assembled into a sensor array. The multi-ionophore array performance was evaluated in the analysis of Ln3+ mixtures and compared to that of conventional monoionophore sensors. It was demonstrated that a multi-ionophore array can yield RMSEP (root mean-squared error of prediction) values not exceeding 0.15 logC for quantification of individual lanthanides in binary mixtures in a concentration range 5 to 3 pLn3+.

Association between prenatal rare earth elements exposure and premature rupture of membranes: Results from a birth cohort study

The widespread exploitation and application of rare earth elements (REE) have led to the risk of human exposure and might result in the adverse health effect on pregnant women. However, no epidemiological studies have explored the associations between prenatal REE exposure and premature rupture of membranes (PROM). We aimed to investigate the associations of maternal urinary REE levels with the risk of PROM. A total of 4897 mother-newborn pairs were recruited from a birth cohort study in Wuhan, China. Urinary concentrations of REE were measured by inductively coupled plasma mass spectrometry (ICP-MS). The associations of prenatal REE exposure with PROM were evaluated using logistic regression models. False discovery rate (FDR) was applied to adjust for multiple testing. Weighted quantile sum (WQS) regression was used to estimate the association of urinary REE mixture with PROM. With one unit increase (μg/g creatinine) in natural log-transformed urinary REE levels (Ce, Yb, La, Pr, Nd, Eu, Gd, Dy, Ho, Er, Tm), the adjusted ORs (95% CIs) for the PROM were from 1.143 (1.078, 1.211) to 1.317 (1.223, 1.419), and the associations were still observed after FDR adjustment (all PFDRs<0.05). The associations were stronger among male infants than female infants. Furthermore, the urinary REE mixture was also associated with the risk of PROM, a quartile increase in the WQS index of REE resulted in ORs (95% CI) for the PROM of 1.494 (1.356, 1.645) in the adjusted model. Our findings suggested that prenatal exposure to REE (Ce, Yb, La, Pr, Nd, Eu, Gd, Dy, Ho, Er, and Tm) and REE mixture were associated with the increased risk of PROM. Further studies from different populations are needed to confirm the associations and to explore the mechanisms.

Rare Earth Extraction using Solvent Extraction: Which Factor Has the Most Significant Impact?

Using a two-level factorial design, a study was undertaken to change the parameters impacting the recovery of rare earth from rare earth mixture. The experimental design was used to screen and identify the major contributing aspects to rare earth recovery. The experiment aims to isolate samarium from a mixture of samarium, europium, and gadolinium. Factors involved consist of pH (pH 1 and pH 6), acid type (nitric acid and hydrochloric acid) and concentration (1.0M and 5.0M), mixing duration (30 min and 120 min), feed composition (20% samarium and 80% samarium), type of diluent (hexane and chloroform), temperature (room temperature and 60°C) and organic to aqueous phase ratio (1:1 and 2:1). The results showed that the samarium recovery was in the range of 0.98% to 90.88%. Based on analysis variance (ANOVA), five factors significantly affect the samarium recovery out of eight factors explored. The five factors according to the most significant order are pH&gt; feed composition&gt; organic to aqueous phase ratio&gt;acid concentration&gt;acid type&gt;mixing duration&gt;type of diluent&gt; temperature. Statistical analysis shows that the linear model is significant, with the value of R2 is 0.9886. Based on the statistical data, five significant variables influence the separation of samarium. This research shows that two-level factorial design can anticipate significant variables impacting rare earth separation, particularly samarium, in the solvent extraction process.

Rare earth elements in umbilical cord and risk for orofacial clefts

Questions remain about the effects of rare earth elements (REEs) on reproductive health, and no study has explored in utero exposure to REEs and risk of orofacial clefts (OFCs). We recruited subjects from a case-control study conducted in Shanxi Province, China. Concentrations of fifteen REEs were quantified in umbilical cord samples by means of Inductively Coupled Plasma Mass Spectrometry measurements. We employed logistic regression and weighted quantile sum (WQS) regression models to estimate the association between REEs exposures and OFCs. Of 226 subjects included in our study, 34 were cleft lip only, 44 were cleft lip with cleft palate and 6 were cleft palate only. In the logistic regression model, concentrations above the median of all subjects were associated with an increased OFCs risk of 2.35-fold (95% CI: 1.22, 4.53) for Lanthanum and 2.12-fold for Neodymium (95% CI: 1.10, 4.10) adjusting for maternal age, BMI, gestational weeks, sex of infants and passive smoking. In WQS model, a quartile increase in the index resulting in an increase of 3.10 (95% CI: 1.38, 6.96) in the odds of OFC. Lanthanum and Neodymium were suggested to be important factors. The results were largely consistent for OFC subtypes. In conclusion, in utero exposure to mixtures of REEs increased the risk of OFCs. Lanthanum and Neodymium were likely to be important factors in the development of OFCs.

Foam flotation of rare earth elements by conventional and green surfactants

Foam (ion and precipitate) flotation is a promising green method of recovery of rare earth elements (REE) from leachates of the primary and secondary resources. However, the capabilities of foam flotation in solutions simulating real leachates are currently poorly understood, especially for green surfactants as collectors. In this work, we report the results of foam flotation of La(III), Ce(III), Gd(III), and Yb(III) ions individually, as a group, and as a group with gangue ions (Al(III), Zn(II), Ca(II), and Mg(II)). These REE represent both light and heavy REE. As the collectors, we test two quintessential synthetic and green anionic surfactants—sodium dodecyl sulfate (SDS) and mono-rhamnolipid, respectively. We find that the floatability of REE with SDS depends considerably on the composition of the REE solution and demonstrate that the recovery kinetics can be used as additional control of the REE separation in the group flotation with gangue ions. Another important finding is that mono-rhamnolipid at a concentration as low as 10 μM can recover up to 100% REE in the group flotation against gangues, except for Al(III) and Zn(II). At pH 9, mono-rhamnolipid selectively removes REE in the group flotation with gangue cations at a surfactant:total cation (excluding Na+) ratio as low as 1:13. We offer an interpretation of the effects observed. Overall, our results demonstrate that foam flotation is capable of selectively recovering an individual REE from a mixture of several REE with gangue ions, provided that the flotation conditions such as surfactant structure, surfactant concentration, solution pH, and flotation time are properly selected. These results are an important milestone toward the commercialization of foam flotation for the recovery and purification of REE.

First attempt to assess ecotoxicological risk of fifteen rare earth elements and their mixtures in sediments with diffusive gradients in thin films

Rare earth elements (REEs) are emerging contaminants due to their large scale of exploitation worldwide for using in the high-technology sector. Diffusive gradients in thin films (DGT) are a good method to measure the bioaccessibility of inorganic substances. This study is the first to evaluate the combined toxicity of REEs in sediments to aquatic biota using the DGT technique. The intertidal zone of the Pearl River Estuary (PRE) was selected as a case study, as the upper reaches of the Pearl River is a major REE reserve and production region. The DGT-labile measured concentrations of REEs (∑REEs) were found to range from 7.02–16.06 μg/L in intertidal surface sediments of the PRE. Assessment of single REE toxicity found that risk quotient (RQ) values for Y, Pr, Nd, Eu, Dy, Er, and Yb are significantly higher than 1, indicating that the adverse effects of these single REEs should be not ignored. The combined toxicity of REE mixtures based on probabilistic ecotoxicological risk assessment, shows that intertidal surface sediments of PRE had a low probability (3.72%) of toxic effects to aquatic biota.

Study on the Extraction and Separation of Samarium from Chloride Medium Using D2EHPA and [P66614][D2EHP] and Their Application to Monazite Ore

The present work deals with the investigation of solvent extraction of Sm(III) from chloride medium using di-(2-ethylhexyl)phosphoric acid (D2EHPA) and trihexyl tetradecyl phosphonium bis(2-ethylhexyl)phosphate ([P66614][D2EHP]) as extractants. In the extraction stage, the effect of contact time, aqueous phase pH, extractant concentration, NaCl concentration, temperature effect, stripping and O:A ratio variation are investigated to compare the extraction abilities of D2EHPA and the ionic liquid made from that. The complex formation ability and extraction mechanism of samarium with two extractants are explained by FTIR spectra and slope analysis method. Solvent extraction of samarium is better noticeable with D2EHPA than that of [P66614][D2EHP]. It is evident that with rise in pH of the aqueous medium, the extraction percentage of samarium is increased for both the extractants. Optimum extraction (100%) of Sm3+ is obtained with 0.1 mol/L D2EHPA and 0.1 mol/L [P66614][D2EHP], respectively. HNO3 is the best stripping agent for back-extraction of samarium from the loaded extractants. Separation studies are carried out in the presence of transition metal ions (mostly present in magnets) to know the efficiency of D2EHPA and ionic liquid [P66614][D2EHP]. The extraction studies with mixture of other rare earth metal ions similar to monazite composition follow the order as Gd(III) > Sm(III) > Nd(III) > Ce(III) > La(III) for both the extractants. Using 0.03 mol/L D2EHPA, complete separation of Gd and Sm from the rare earth mixtures is found at two stages with O:A ratio of unity.

Coupling mixture reference models with DGT-perceived metal flux for deciphering the nonadditive effects of rare earth mixtures to wheat in soils

The risk assessment of mixtures of rare earth elements (REEs) is hampered by a lack of fundamental understanding of their interactions in different soil types. Here, we assessed mixture interactions and toxicity to Triticum aestivum of Y and Ce in four different soils in relation to their bioavailability. Mixture toxicity was modelled by concentration addition (CA) and independent action (IA), in combination with different expressions of exposure: three equilibrium-based doses (total soil concentrations [M]tot, free ion activity in soil solution {M3+}, and the fraction (f) of metal ions bound to the biotic ligands (BLs)) and one kinetically controlled dose ([M]flux) metrics. Upon single exposure, REE toxicity was increasingly better described when using exposure expressions based on deepened understanding of their bioavailability: [M]flux > f > {M3+} > [M]tot. The mixture analyses based on [M]tot and {M3+} displayed deviations from additivity depending on the soil type. With the parameters derived from single exposures, the BLM approach gave better predictions of mixture toxicity (R2 ~ 0.70) than when using CA and IA based on either [M]tot or {M3+} (R2 < 0.64). About 30% of the variance in toxicity remained unexplained, challenging the view that the free metal ion is the main bioavailable form under the BLM framework based on thermodynamic equilibrium. Toxicity was best described when accounting for changes in the size of the labile metal pool by using a kinetically controlled dose metric (R2 ~ 0.80). This suggests that dynamic bioavailability analysis could provide a robust basis for modeling and reconciling the interplays and toxicity of metal mixtures in different soils.

Extraction chromatography of 225Ac and lanthanides on N,N-dioctyldiglycolamic acid /1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide solvent impregnated resin

The alpha-emitter 225Ac (t1/2 = 9.92 d) is currently under development for targeted alpha-particle therapy of cancer, and accelerator production of 225Ac via proton irradiation of thorium targets requires robust separations of 225Ac from chemically similar fission product lanthanides. Additionally, the lanthanide elements represent critical components in modern technologies, and radiolanthanides such as 140Nd (t1/2 = 3.37 d) also have potential application in the field of nuclear medicine. The ionic liquid, 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([Bmim][NTf2]), combined with the diglycolamide extractant, N,N-dioctyldiglycolamic acid (DODGAA), was adsorbed on macroporous resin support to produce a solvent impregnated resin (SIR) that was investigated for separations of 225Ac and lanthanides. The equilibrium distribution coefficients (Kd) of the rare earth elements (Sc(III), Y(III), Ln(III)), 225Ac(III), Th(IV), and U(VI) on the prepared DODGAA/[Bmim][NTf2]-SIR were determined from batch adsorption experiments in HCl and HNO3 media. The DODGAA/[Bmim][NTf2]-SIR exhibited preferential uptake of the heavier lanthanide elements while allowing for the separation of the lighter lanthanides. Column separations utilizing the DODGAA/[Bmim][NTf2]-SIR were effective at separating the lighter lanthanides from each other, and separating 225Ac from a mixture of lanthanides, 213Bi, and 225Ra without the need for additional complexing agents.