Measurement Range Research Articles

Electron–phonon coupling and a resonant-like optical observation of a band inversion in topological crystal insulator Pb1−x Sn x Se

The optical reflectivity of n-type Pb0.865Sn0.135Se and Pb0.75Sn0.25Se solid solutions was measured in the THz spectral region energetically corresponding to optical phonon excitations and in the temperature range from 40 K to 280 K. The first solid solution exhibits an open energy gap with trivial band ordering at all temperatures, while for the second one the transition from trivial insulator to topological crystal insulator phase is expected. The analysis of Pb0.75Sn0.25Se data performed within the dynamic dielectric function formalism revealed an anomaly of resonance-like character in the temperature dependence of LO phonon frequency. The formula for LO phonon energy renormalization reproduced observed anomaly for energy gap equal to zero, the phase transition occurred at T 0 = (172 ± 2) K. This effect was absent for Pb0.865Sn0.135Se. Present results show that reflectivity measurements in the THz range in the vicinity of LO phonon frequency can be valuable experimental method for precise determining of band inversion temperature in narrow-gap topological materials.

Clinical results and computed tomography analysis of intuitive shoulder arthroplasty (ISA) stemless at a minimum follow-up of 2 years

IntroductionThe utilization of stemless anatomic total shoulder arthroplasty is on the rise. Epiphyseal fixation leads to radiological bone remodeling, which has been reported to exceed 40% in certain studies series. The aim of this study was to present the clinical and radiological outcomes of a stemless implant with asymmetric central epiphyseal fixation at an average follow-up of 31 months. MaterialsThis retrospective multicenter study examined prospective data of patients undergoing total anatomic arthroplasty with ISA Stemless implant and followed up at least 2 years. Clinical assessment included preoperative and final follow-up measurements of active range of motion (ROM), Constant score, and Subjective Shoulder Value (SSV). Anatomical epiphyseal reconstruction and bone remodeling at the 2-year follow-up were assessed by standardized Computed Tomography Scanner (CT scan). Statistical analysis employed unpaired Student's t-test or chi-squared test depending on the variable type, conducted using EasyMedStat software (version 3.22; www.easymedstat.com). ResultsFifty patients (mean age 68 years, 62% females) were enrolled, with an average follow-up of 31 months (24-44). Primary osteoarthritis (68%) with type A glenoid (78%) was the prevailing indication. The mean Constant score and SSV improved significantly from 38 ± 11 to 76 ± 11 (p<0.001) and from 31% ± 16 to 88% ± 15 (p<0.001) respectively at the last follow-up. Forward elevation, external rotation and internal rotation ROM increased by 39° ± 42, 28° ± 21 and 3,2 ± 2,5 points respectively, surpassing the Minimally Clinically Important Difference (MCID) after total shoulder arthroplasty. No revisions were necessary. CT scans identified 30% osteolysis in the posterior-medial calcar region, devoid of clinical repercussions. No risk factors were associated with bone osteolysis. ConclusionAt an average follow-up of 31 months, ISA Stemless implant provided favorable clinical results. CT analysis revealed osteolysis-like remodeling in the posterior-medial zone of the calcar (30%), without decline in clinical outcomes and revisions. Long-term follow-up studies are mandated to evaluate whether osteolysis is associated with negative consequences.

ElecFeX is a user-friendly toolbox for efficient feature extraction from single-cell electrophysiological recordings

Characterizing neurons by their electrophysiological phenotypes is essential for understanding the neural basis of behavioral and cognitive functions. Technological developments have enabled the collection of hundreds of neural recordings; this calls for new tools capable of performing feature extraction efficiently. To address the urgent need for a powerful and accessible tool, we developed ElecFeX, an open-source MATLAB-based toolbox that (1) has an intuitive graphical user interface, (2) provides customizable measurements for a wide range of electrophysiological features, (3) processes large-size datasets effortlessly via batch analysis, and (4) yields formatted output for further analysis. We implemented ElecFeX on a diverse set of neural recordings; demonstrated its functionality, versatility, and efficiency in capturing electrical features; and established its significance in distinguishing neuronal subgroups across brain regions and species. ElecFeX is thus presented as a user-friendly toolbox to benefit the neuroscience community by minimizing the time required for extracting features from their electrophysiological datasets.

High-Performance Relative Localization Based on Key-Node Seeking Considering Aerial Drags Using Range and Odometry Measurements

High-Performance Relative Localization Based on Key-Node Seeking Considering Aerial Drags Using Range and Odometry Measurements

Motion Modeling and State Estimation With Bistatic Range and Doppler Measurements

Motion Modeling and State Estimation With Bistatic Range and Doppler Measurements

An ADMM approach for elliptic positioning in non-line-of-sight environments

Elliptic positioning (EP) has recently emerged as a prevailing subject within localization research, holding significant relevance for a variety of multistatic systems including distributed multiple-input multiple-output radar, sonar, and wireless sensor networks. Mathematically, EP refers to estimating the location of a signal-reflecting/relaying target from the bistatic range (BR) measurements acquired by employing multiple spatially separated transmitters and receivers. BRs, as a specific type of range-based sensor observations, will however be positively biased when non-line-of-sight (NLOS) signal propagation occurs. Such a phenomenon is widespread across various localization scenarios, which can seriously degrade the positioning accuracy if not properly addressed. Through the alternating direction method of multipliers, this contribution introduces a computationally efficient iterative algorithm designed for error-mitigated EP in NLOS environments. In addition to target position coordinates, we incorporate a non-negatively bounded balancing parameter into the formulation and perform joint estimation, thereby achieving NLOS bias error reduction in a simple yet impactful manner. Numerical simulations are conducted to validate the functionality of the presented EP approach in NLOS situations.

Pattern Correction From Nonideal Compact Antenna Test Range Measurement

Pattern Correction From Nonideal Compact Antenna Test Range Measurement

Forecasting the BAO measurements of the CSST galaxy and AGN spectroscopic surveys

ABSTRACT The spectroscopic survey of the China’s Space Survey Telescope (CSST) is expected to obtain a huge number of slitless spectra, including more than one hundred million galaxy spectra and millions of active galactic nuclei (AGNs) spectra. By making use of these spectra, we can measure the Baryon Acoustic Oscillation (BAO) signals over large redshift ranges with excellent precisions. In this work, we predict the CSST measurements of the post-reconstruction galaxy power spectra at $0\lt z\lt 1.2$ and pre-reconstruction AGN power spectra at $0\lt z\lt 4$, and derive the BAO signals at different redshift bins by constraining the BAO scaling parameters using the Markov Chain Monte Carlo method. Our result shows that the CSST spectroscopic survey can provide accurate BAO measurements with precisions higher than 1 and 3 per cent for the galaxy and AGN surveys, respectively. By comparing with current measurements in the same range at low redshifts, this can improve the precisions by a factor of $2\sim 3$, and similar precisions can be obtained in the pessimistic case. We also investigate the constraints on the cosmological parameters using the measured BAO data by the CSST, and obtain stringent constraint results for the energy density of dark matter, Hubble constant, and equation of state of dark energy.

Motion Capture-based 3-dimensional Measurement of Range of Motion in Patients Undergoing Cervical Laminoplasty.

A prospective study. To measure 3-dimensional cervical range of motion (ROM) by noninvasive optical tracking-based motion-capture technology in patients undergoing laminoplasty, and to elucidate the postoperative effects of laminoplasty on cervical mobility. Cervical laminoplasty is a motion-sparing decompression surgery for degenerative cervical myelopathy. Unlike cervical laminectomy and fusion, the true postoperative impact of laminoplasty on neck motion has not been well studied. Participants comprised 25 patients undergoing double-door cervical laminoplasty for degenerative cervical myelopathy in a single center. Maximum flexion/extension, left/right rotation, and left/right side bending were recorded using the motion-capture device preoperatively and 3 months postoperatively. ROMs in 3 orthogonal axes were calculated. Preoperative differences in C2-7 Cobb angles on lateral flexion/extension x-rays were also measured as the radiologic ROM to assess reliability. Preoperative and 1-year postoperative Japanese Orthopaedic Association score, Neck Disability Index [NDI], and Euro-QOL were recorded, and correlations with ROMs were assessed. Preoperative mean (±SD) ROMs for flexion/extension, rotation, and side bending were 90±17, 107±16, and 53±17 degrees, respectively. Although radiologic sagittal ROM measurement showed a smaller range than motion capture, averaging 36±13 degrees, a moderate to strong correlation between radiologic and motion capture values was observed (R=0.57, P=0.003). Preoperative NDI showed a negative correlation with coronal ROM (rho=-0.547, P=0.02). Postoperative ROM showed a significant reduction in rotation (95±16 degrees, P=0.002) but not in flexion/extension or side bending. Three-dimensional motion-capture analysis allowed reliable measurement of cervical ROM. Rotational ROM was significantly reduced after laminoplasty, showing that cervical kinematics are still significantly altered.

Role of hypoxia-mediated pyroptosis in the development of extending knee joint contracture in rats

Joint contracture is one of the common diseases clinically, and joint capsule fibrosis is considered to be one of the most important pathological changes of joint contracture. However, the underlying mechanism of joint capsule fibrosis is still controversial. The present study aims to establish an animal model of knee extending joint contracture in rats, and to investigate the role of hypoxia-mediated pyroptosis in the progression of joint contracture using this animal model. 36 male SD rats were selected, 6 of which were not immobilized and were used as control group, while 30 rats were divided into I-1 group (immobilized for 1 week following 7 weeks of free movement), I-2 group (immobilized for 2 weeks following 6 weeks of free movement), I-4 group (immobilized for 4 weeks following 4 weeks of free movement), I-6 group (immobilized for 6 weeks following 2 weeks of free movement) and I-8 group (immobilized for 8 weeks) according to different immobilizing time. The progression of joint contracture was assessed by the measurement of knee joint range of motion, collagen deposition in joint capsule was examined with Masson staining, protein expression levels of HIF-1α, NLRP3, Caspase-1, GSDMD-N, TGF-β1, α-SMA and p-Smad3 in joint capsule were assessed using western blotting, and the morphological changes of fibroblasts were observed by transmission electron microscopy. The degree of total and arthrogenic contracture progressed from the first week and lasted until the first eight weeks after immobilization. The degree of total and arthrogenic contracture progressed rapidly in the first four weeks after immobilization and then progressed slowly. Masson staining indicated that collagen deposition in joint capsule gradually increased in the first 8 weeks following immobilization. Western blotting analysis showed that the protein levels of HIF-1α continued to increase during the first 8 weeks of immobilization, and the protein levels of pyroptosis-related proteins NLRP3, Caspase-1, GSDMD-N continued to increase in the first 4 weeks after immobilization and then decreased. The protein levels of fibrosis-related proteins TGF-β1, p-Smad3 and α-SMA continued to increase in the first 8 weeks after immobilization. Transmission electron microscopy showed that 4 weeks of immobilization induced cell membrane rupture and cell contents overflow, which further indicated the activation of pyroptosis. Knee extending joint contracture animal model can be established by external immobilization orthosis in rats, and the activation of hypoxia-mediated pyroptosis may play a stimulating role in the process of joint capsule fibrosis and joint contracture.

Определение точности измерения дальности между подводными объектами при помощи гидроакустических модемов

В работе представлены результаты экспериментального исследования точности определения дальности между подводными объектами при помощи гидроакустических модемов uWave в условиях ледового эксперимента в мелком водоёме. Проведены две независимые проверки: определение фактической скорости звука на основе относительных измерений, и определение дальностей на основе скорости звука, вычисленной по измерению температуры встроенными в модемы датчиками. Общий размер выборки составляет 1260 измерений времени распространения сигнала, выполненных в 10 различных взаимных расположений двух объектов. Проведён анализ источников погрешностей, в ходе которого, в частности, выявлена линейная зависимость роста среднеквадратичного отклонения измерений времени распространения с дальностью. В качестве источника указан эффект удлинения траекторий лучей в виду нелинейности распространения звука в среде. Экспериментальная проверка точности определения времени распространения сигнала и наклонной дальности между модемами uWave показала, что среднеквадратичное отклонение имеет порядок 0.1% от дальности. The paper presents the results of an experimental study of the accuracy of measurment of the distance between underwater objects using uWave underwater acoustic modems under the conditions of an ice experiment in a shallow water body. Two independent tests were carried out: determining the actual speed of sound based on relative measurements, and determining ranges based on the speed of sound calculated from temperature measurements by sensors built into modems. The total sample size is 1260 signal propagation time measurements taken at 10 different relative positions of the two objects. An analysis of the sources of errors was carried out, during which, in particular, a linear dependence of the increase in the standard deviation of propagation time measurements with range was revealed. The source indicated is the effect of lengthening ray trajectories due to the nonlinearity of sound propagation in the medium. An experimental test of the accuracy of determining the signal propagation time and slant range between uWave modems showed that the standard deviation is on the order of 0.1% of the range.

Extending the PROMIS item bank “ability to participate in social roles and activities”: a psychometric evaluation using IRT

ObjectiveOur objective was to explore whether the extension of the PROMIS item bank Ability to Participate in Social Roles and Activities (APSRA) with new items would result in more effective targeting (i.e., selecting items that are appropriate for each individual's trait level), and more reliable measurements across all latent trait levels.MethodsA sample of 1,022 Dutch adults completed all 35 items of the original item bank plus 17 new items (in Dutch). The new items presented in this publication have been translated provisionally from Dutch into English for presentation purposes. We evaluated the basic IRT assumptions unidimensionality, local independence, and monotonicity. Furthermore, we examined the item parameters, and assessed differential item functioning (DIF) for sex, education, region, age, and ethnicity. In addition, we compared the test information functions, item parameters, and θ scores, for the original and extended item bank in order to assess whether the measurement range had improved.ResultsWe found that the extended item bank was compatible with the basic IRT assumptions and showed good reliability. Moreover, the extended item bank improved the measurement in the lower trait range, which is important for reliably assessing functioning in clinical populations (i.e., persons reporting lower levels of participation).ConclusionWe extended the PROMIS-APSRA item bank and improved its psychometric quality. Our study contributes to PROMIS measurement innovation, which allows for the addition of new items to existing item banks, without changing the interpretation of the scores and while maintaining the comparability of the scores with other PROMIS instruments.

Humidity Sensing Using a Multimode Fiber Ring Laser with Thermal Compensation

We propose a multimode fiber laser sensor utilizing PI-SMF (polyimide-coated single mode fiber) for low-error relative humidity (RH) measurement, which is temperature compensated based on FBG. The PI-SMF in the laser cavity is used as a sensing element, and its length varies with humidity and temperature by volume-variation induced strain, which leads to frequency shift of the longitudinal mode beat frequency signal (BFS). When the 2000 MHz BFS is selected as the sensing signal, a RH sensitivity of −2.68 kHz/%RH and a temperature sensitivity of −14.05 kHz/°C are achieved. The peak shift of the FBG-based laser emission spectrum is only sensitive to temperature rather than RH with a temperature sensitivity of 9.95 pm/°C, which is used as the temperature compensation for RH measurements. By monitoring the response of the BFS and the laser wavelength, the cross-sensitivity effect of RH and temperature is overcome, and low-error RH measurement in the temperature range of 20 to 65 °C is realized with errors within ±0.67 %RH (25 to 85 %RH). The scheme does not require the design and production of complex structures and hygroscopic material coating processes, owning the advantages of simple structure, easy operation and high accuracy, and is expected to be practically applied in food safety and environmental monitoring.

Low temperature PECVD processes for the fabrication of integrated symmetrical resonant UV210 organic/semiconductor structures

The resonant structures used as sensors for investigating specific dark and opaque substances may pose difficulties due to their potential aggressiveness towards photonic chips and the risk of destruction upon contact. To avoid it, this study presents a detailed description of a novel symmetrical waveguide structure with UV210 enclosed between Si/SiO2 bi-layers implemented for integrated photonics. The fabrication process is thoroughly explained, accompanied by various analyses conducted for characterizations purposes. The structure is composed of an organic UV210 material developed using deep UV lithography at 248 nm and fabricated onto an oxidized silicon layer, resulting in a Si/SiO2 bi-layer configuration. This process enables the fabrication of µm-scale access waveguides and racetrack Micro-Resonators (MRs) with a 400-nanometers gap. Several multilayer families have been produced using various low-temperature PECVD processes to obtain symmetrical Si/SiO2/UV210/Si/SiO2 structures and then properly characterized using non-destructive analyses and imaging techniques. The advantage of structural symmetry is primarily related to the electromagnetism and guidance equations, which eliminate the requirement for a cut-off thickness (or frequency), enabling significant miniaturization. Additionally, the upper cladding composed of a Si/SiO2 bi-layer offers protection against potentially aggressive substances directly in contact with the organic waveguide core and MRs. Different bi-layer upper cladding families, produced under various PECVD conditions, were characterized using XPS to understand the bonding mechanism between the silicon and UV210 organic. In addition, ellipsometric analyses were conducted to determine the real and imaginary components of the refractive index of the global structure and the upper cladding bi-layer. Structure imaging were obtained by Raman analyses and optical statistical measurements were conducted on four different types of heterostructures, with silica temperatures ranging from 120°C to 150°C during the second PECVD process. The resonance analysis, performed through Free Spectral Range (FSR) measurements, allowed us to draw conclusions regarding the stability and reproducibility of the fabrication process, as well as the impact of PECVD processes conditions on the optical measurements. Such optoelectronic resonant elements and hybrid heterostructures enable the investigation of aggressive substances in direct contact.

Experiments with Combining LiDAR and Camera Data Acquired by UAS and Smartphone to Support Mapping

Abstract. Aerial mapping using Unmanned Aerial Systems (UAS), such as the DJI Mavic 3 Enterprise, has revolutionized photogrammetry, enabling efficient data capture for small-scale projects. The typical nadir perspective of UAS mapping, however, imposes limitations on capturing critical details of features due to its predominantly vertical viewpoint. Overcoming this challenge often requires manual, low-altitude flights by experienced UAS pilots to achieve high-angle oblique perspectives, unless gimbled camera mount is used. This study explores the integration of high oblique angle perspectives using the iPhone 15 Pro, which boasts advanced camera capabilities and an integrated LiDAR sensor, to complement UAS imagery. The iPhone 15 Pro's camera sensors provide a Ground Sampled Distance (GSD) comparable to UAS cameras, while its LiDAR sensor, with about five meters of range, enhances mapping capabilities by delivering accurate depth measurements in close range. By utilizing various georeferencing options for the imagery and LiDAR data from the iPhone 15 Pro with UAS nadir imagery, we can achieve a more comprehensive object space reconstruction, significantly improving the accuracy of geospatial mapping. Both the Mavic 3 Enterprise and the iPhone 15 Pro, though operating independently on their respective platforms, support Real-Time Kinematic (RTK) corrections, facilitating precise positioning for the entire system trajectory. Strategic placement and utilization of Ground Control Points (GCPs) aid in the georeferencing of the complete dataset, enhancing its overall accuracy. To validate the accuracy of the acquired data, checkpoints are established on-site. The positions derived from the integrated UAS and iPhone 15 Pro data are compared against these checkpoints to quantify the accuracy and reliability of the data. Additionally, Post-Processed Kinematic (PPK) techniques are employed to validate the trajectories of all data collection systems, ensuring the reliability of the acquired data, especially in instances where RTK corrections may be lacking. In summary, this research showcases comprehensive, multi-dimensional geospatial datasets by conducting validation studies that assess the accuracy and reliability of georeferenced datasets against known ground truth checkpoints. Such validation studies are crucial for identifying gaps in current methodologies and suggesting areas for improvement, thereby aiming to enhance the quality and accuracy of geospatial mapping applications. Through the integration of UAS and smartphone mapping, complemented by rigorous validation efforts, we aspire to achieve improved geospatial mapping accuracy.

Greatly Enhanced Radiative Transfer Enabled by Hyperbolic Phonon Polaritons in α‐MoO3

AbstractOrthorhombic molybdenum trioxide (α‐MoO3) is a highly anisotropic hyperbolic material in nature. Within its wide Reststrahlen bands, α‐MoO3 has hyperboloidal dispersion that supports bulk propagation of high‐k phonon polariton modes. These modes can serve as energy transport channels to greatly enhance radiative heat transfer inside the material. In this work, large radiative transfer enabled by phonon polaritons in α‐MoO3 is demonstrated. The study first determines the temperature‐dependent permittivity of α‐MoO3 from polarized Fourier‐Transform Infrared (FTIR) spectroscopy measurements and then uses a many‐body radiative heat transfer model to predict the equivalent radiative thermal conductivity of hyperbolic phonon polariton. Contribution of radiative transfer to the total thermal transport is experimentally determined from the Time‐Domain Thermoreflectance (TDTR) measurements in a temperature range from −100 to 300 °C. It is found that radiative transfer can account for ≈60% of the total thermal transport at a temperature of 300 °C. That is, conductive thermal transport is enhanced by &gt;100% by radiative transfer, or radiation inside α‐MoO3 is greater than that of conduction. These additional energy pathways will have important implications in thermal management in new materials and devices.

Quality of life, craniomandibular function, and psychosocial factors related to pain and movement in patients with head and neck cancer.

To describe the characteristics of and the associations between health-related quality of life, pain, craniomandibular function, and psychosocial factors related to pain and fear of movement in patients with head and neck cancer. Seventy-eight patients diagnosed with HNC were recruited. Measurements of the maximum mouth opening range and pressure pain thresholds on the masseter muscle and the distal phalanx of the thumb were conducted, as well as a battery of self-report questionnaires were administrated, including the QoL Questionnaire (EORT QLQ-H&N35), Numeric Rating Scale (NRS), Pain Catastrophizing Scale (PCS), the Spanish translation of the Tampa Scale for Kinesiophobia for Temporomandibular Disorders (TSK-TMD), and the short version of the Craniofacial Pain and Disability Inventory (CF-PDI-11). The study sample (66.7% men, mean age 60.12 [11.95] years) experienced a moderate impact on their QoL levels (57.68 [18.25] EORT QLQ-H&N35) and high kinesiophobia values (20.49 [9.11] TSK-TMD). Pain was present in 41% of the patients, but only 3.8% reported severe pain. 26.4% had a restricted mouth opening range, and 34.62% showed significant catastrophism levels. There were strong positive correlations between EORT QLQ-H&N35 and CF-PDI-11 (r = 0.81), between NRS and CF-PDI-11 (r = 0.74), and between PCS and CF-PDI-11 (r = 0.66). Patients with HNC experience negative effects in their QoL, related to their impairment in craniomandibular function. Fear of movement, pain intensity, and catastrophism are associated with poorer functionality; relationships that should be considered when attempting to improve health care.

RBFNN-based angles-only orbit determination method for non-cooperative space targets

Angles-only orbit determination during space situational awareness missions for non-cooperative targets such as space debris is subject to the well-known observability problem, that is, the orbital state is weakly observable or even unobservable because of missing range measurements. The key point to solve this problem is how to quickly capture the nonlinearity of orbit dynamics if only one space-based passive sensor is available to observe the target and translational maneuvers are not executed. To solve the short-arc angles-only problem, this study develops a simple and fast orbit determination method by exploiting the advantages of radial basis function neural network (RBFNN). Emphasis was placed on the design of the RBFNN, which was trained to construct a mapping network model from line-of-sight (LOS) measurements to the relative orbit. First, the perturbed relative orbit dynamics considering the Earth's non-spherical J2 term and air drag was established with the LOS measurement model. Second, a RBFNN-based angles-only orbit determination frame was developed, in which the generator of the training dataset, data preprocessing algorithm, and RBF network structure were designed. Finally, the proposed method was verified and tested using a set of numerical simulations of low-Earth orbit cases. The anti-noise and generalization performance of the designed network and the sensitivity of the solution accuracy to the measurement frequency and span were presented and discussed. Additionally, the advantages of the RBFNN-based method were confirmed by comparison with the results obtained using the BPNN (Back Propagation Neural Network)-based method. The simulation results show that the average orbit prediction error for LEO scenarios is approximately 0.08% using the index of initial relative distance, where only three sets of LOS angles are measured within a span of 24 s.

Noninvasive release of tendons using MRI guided focused ultrasound: a hybrid therapy using long-pulse focused ultrasound followed by thermal ablation

Introduction Magnetic Resonance-guided Focused Ultrasound (MRgFUS) thermal ablation is an effective noninvasive ultrasonic therapy to disrupt in vivo porcine tendon but is prone to inducing skin burns. We evaluated the safety profile of a novel hybrid protocol that minimizes thermal spread by combining long-pulse focused ultrasound followed by thermal ablation. Methods In-vivo Achilles tendons (hybrid N = 15, thermal ablation alone N = 21) from 15 to 20 kg Yorkshire pigs were randomly assigned to 6 treatment groups in two studies. The first (N = 21) was ablation (600, 900, or 1200 J). The second (N = 15) was hybrid: pulsed FUS (13.5 MPa peak negative pressure) followed by ablation (600, 900, or 1200 J). Measurements of ankle range of motion, tendon temperature, thermal dose (240 CEM43), and assessment of skin burn were performed in both groups. Results Rupture was comparable between the two protocols: 1/5 (20%), 5/5 (100%) and 5/5 (100%) for hybrid protocol, compared to 2/7 (29%), 6/7 (86%) and 7/7 (100%) for the ablation-only protocol with energies of 600, 900, and 1200 J, respectively. The hybrid protocol produced lower maximum temperatures, smaller areas of thermal dose, fewer thermal injuries to the skin, and fewer full-thickness skin burns. The standard deviation for the area of thermal injury was also smaller for the hybrid protocol, suggesting greater predictability. Conclusion This study demonstrated a hybrid MRgFUS protocol combining long-pulse FUS followed by thermal ablation to be noninferior and safer than an ablation-only protocol for extracorporeal in-vivo tendon rupture for future clinical application for noninvasive release of contracted tendon.

Performance of a High-Speed Pyroelectric Receiver as Cryogen-Free Detector for Terahertz Absorption Spectroscopy Measurements

The application of terahertz (THz) radiation in scientific research as well as in applied and commercial technology has expanded rapidly in recent years. One example is the progress in high-resolution THz spectroscopy based on quantum cascade lasers, which has enabled new observations in astronomy, atmospheric research, and plasma diagnostics. However, the lack of easy-to-use and miniaturised detectors has hampered the development of compact THz spectroscopy systems out of the laboratory environment. In this paper, we introduce a new high-speed pyroelectric receiver as a cryogen-free detector for THz absorption spectroscopy. Its performance is characterised by absorption spectroscopy measurements on a reference gas cell (RGC) with ammonia using a tunable THz quantum cascade laser at approximately 4.75 THz as the light source. It is shown that the receiver can record spectra up to 281 Hz without any artefacts to the observed spectral absorption profile, and the results reproduce the known pressure of ammonia in the RGC. This demonstrates that the pyroelectric receiver can be reliably used as an alternative to helium-cooled bolometers for absorption spectroscopy measurements in the THz range, with its main advantages being the high bandwidth, compactness, relatively low cost, and room-temperature operation. Its simplicity and high sensitivity make this receiver a key component for compact THz spectroscopy systems.