Random Grouping Method Research Articles

Repetitive transcranial magnetic stimulation as add-on therapy in persistent postural-perceptual dizziness

BackgroundThis study aims to evaluate the clinical effectiveness of repetitive transcranial magnetic stimulation (rTMS) when used as an add-on therapy for individuals with persistent postural-perceptual dizziness (PPPD). MethodsIn this randomized controlled, double-blind trial conducted at Shangluo Central Hospital, patients with PPPD diagnosed in the neurology departments were included. Participants were randomized into a rTMS treatment group and a control group in a 1:1 ratio by the randomized grouping method. Patients in both groups received conventional treatment, with the rTMS treatment group underwent daily rTMS sessions, whereas the control group received sham rTMS treatments following the same schedule. The effectiveness of the treatments was primarily assessed using the Dizziness Handicap Inventory (DHI), Hamilton Anxiety Rating Scale (HAMA), and Hamilton Depression Rating Scale (HAMD), which measured symptoms of vertigo, anxiety, and depression at baseline, after two weeks, and at the end of four weeks. FindingsOf the 46 participants recruited, 2 were excluded due to contraindications, 22 were randomly assigned to the rTMS treatment group, and 22 were assigned to the control group. Ultimately, 2 withdrew for personal reasons, and data from 42 participants were included in the outcome analysis. HAMA, HAMD and DHI scores were significantly lower in the rTMS treatment group than in the control group after 4 weeks of treatment (p<0.05). A positive correlation was also observed between DHI scores and HAMA or HAMD scores. ConclusionsThis pilot study demonstrated that rTMS is a beneficial add-on therapy for patients with PPPD.

Association of CTACK, IL-2, and IL-13 with increased risk of lung cancer: A Mendelian randomization study

BackgroundIn recent years, relevant studies have reported that inflammatory cytokines are related to the occurrence of cancer. However, the correlation with lung cancer is not clear. This study used the Mendelian random grouping method to investigate the correlation between inflammatory factors and lung cancer in different populations. MethodsWe obtained the single nucleotide polymorphisms (SNPs) of inflammatory cytokines through the open database and the SNPs of lung cancer (European and East Asian) through the IEU OpenGWAS project. Inverse variance-weighted (IVW) MR analyses were used to determine the causalities of exposures and outcomes. Supplementary analyses were also performed using weighted median and MR-Egger regressions. Afterward, sensitivity analyses were performed to test the robustness. Search the ChEMBL database for target drugs and indications for CTACK, IL-2, and IL-13. ResultsBy IVW method, we found that CTACK, IL-2, and IL-13 were associated with an increased risk of lung cancer in the European population (CTACK, OR = 1.098, 95 % CI 1.001–1.204, P = 0.047; IL-2, OR = 1.112, 95 % CI 1.009–1.225, P = 0.032; IL-13, OR = 1.068, 95 % CI 1.007–1.132, P = 0.029), while only IL-13 was associated with an increased risk of lung cancer in the East Asian population (IL-13, OR = 1.110, 95 % CI 1.010–1.220, P = 0.030). The weighted median and MR-Egger regression methods were in the same direction as the IVW effect sizes. Furthermore, no evidence of multidirectionality was detected using the MR-Egger intercept as a sensitivity analysis. Currently, there are no approved or phase III studied indications for CTACK, IL-2, and IL-13 targets in lung cancer. ConclusionThe study outcomes supported that the inflammatory cytokines CTACK, IL-2, and IL-13 increase the risk of lung cancer. There is a lack of indications for drugs in these three targets. We explored the causal relationship between inflammatory cytokines and lung cancer, providing a basis for future cancer prediction models and targets for anti-tumor therapy.

Analysis of the Application Effect of Family Collaborative Care Model on Elderly Patients with Type 2 Diabetes Mellitus and the Situation of Self-Care Ability

Objective: To study the application effect of the family collaborative care model on elderly patients with type 2 diabetes mellitus and its influence on self-care ability. Methods: The elderly type 2 diabetes mellitus patients (400 cases) treated in our hospital between March 2020 and July 2023 were divided into two groups by randomized grouping method; the control group received the conventional nursing program, while the observation group received the family collaborative nursing model. Blood glucose level, self-care ability, and quality of life were compared between the groups. Results: The blood glucose level of the observation group was lower than that of the control group (P &lt; 0.05). The self-care ability and quality of life scores of the observation group were higher than those of the control group (P &lt; 0.05). Conclusion: The family collaborative care model for elderly patients with type 2 diabetes mellitus can promote their self-care ability, improve the effect of glycemic control, and improve their quality of life, and is suitable for further promotion and application.

A Study on the Application of Clinical Pathway Teaching Method in Teaching Gastroenterology Nursing Interns

Objective: To investigate the application effect of the clinical pathway teaching method in the teaching of gastroenterology nursing interns. Methods: 36 interns from the Department of Gastroenterology of our hospital from July 2022 to April 2023 were selected as the study subjects and divided into the control group and the study group (n = 18 each) by randomized grouping method. The control group was given conventional teaching methods and the study group adopted clinical pathway teaching methods. The effect of internship in the two groups was compared. Results: Under the influence of the clinical pathway teaching method, the theoretical knowledge achievement and practical skills of interns in the study group were higher than those in the control group, and the difference was statistically significant (P &lt; 0.05). Conclusion: Compared with the conventional teaching mode, the use of the clinical pathway teaching method in the teaching of nursing interns in gastroenterology can not only realize the optimization and innovation of traditional teaching means, but also mobilize the interns’ enthusiasm, improve their learning interest, and promote the comprehensive improvement of theoretical knowledge and practical skills.

Exploration of Teaching Styles in a Digestive System Integration Course

Purpose: To explore the innovation of teaching methods in digestive system courses and its application effect in the context of curriculum integration. Methods: 60 undergraduate majors of digestive system diseases in the class of 2023 (orientation) of our hospital were divided into 30 students each in the general class and the experimental class using the random grouping method. The general class adopted the case-based learning (CBL) teaching mode, and the experimental class adopted the integrated course mode of CBL + “organ-systems-based curriculum” (OSBC). The teaching effects of the two classes were compared through basic theory and clinical five-station examination. Results: The differences in the basic theory scores and excellence rates of the students in the experimental class were significant (P &lt; 0.05); the clinical 5-station examination suggested that there was no statistical significance in the physical examination of the two classes (P &gt; 0.05); and the differences in the scores of the clinical questioning, case writing, auxiliary examination, and oral examination of the two classes were statistically significant (P &lt; 0.05). Conclusion: The teaching method based on CBL + OSBC integrated course is effective in the teaching reform of the digestive system course and has popularization value.

The Effect of Hysteroscopy Combined with Diane-35 on Endometrial Polyps and Its Impact on the Recurrence Rate

Objective: To analyze the effect of hysteroscopy combined with Diane-35 on endometrial polyps and observe its value in reducing the recurrence rate. Methods: Between June 2022 and January 2023, 90 patients with uterine polyps who met the research criteria were included in the study. A controlled experimental design was employed, and the digital table random grouping method was utilized to divide the patients into the observation and control groups, with 45 cases in each. Patients in the control group underwent hysteroscopic polypectomy, diagnostic curettage during the operation, and routine anti-inflammatory treatment post-surgery. The observation group received Diane-35 treatment after hysteroscopy. The analysis included patient treatment effects, recurrence rate post-surgery, and endometrial thickness. Results: The effective rate among patients treated with combined Diane-35 was 95.56%, which was significantly higher than that among patients treated with hysteroscopy alone (82.22%; χ2 = 4.050, P &lt; 0.05). Both groups were followed up for one year. The recurrence rate in the observation group was 2.22%, significantly lower than that in the control group (13.33%; χ2 = 3.873, P &lt; 0.05). Preoperative endometrial thickness was compared between the two groups, showing no significant difference in the data (P &gt; 0.05). However, at the 6-month and 12-month follow-up post-surgery, the endometrial thickness in the observation group was significantly lower than that in the control group (P &lt; 0.05). After surgery, no adverse reactions such as uterine adhesion, infection, or massive bleeding occurred in either group (P &gt; 0.05). Conclusion: Hysteroscopic surgery combined with Diane-35 yields higher efficacy in patients with endometrial polyps. This approach not only improves surgical outcomes but also reduces the recurrence rate of postoperative polyps and enhances the patient’s endometrial thickness, thus safeguarding the health of female patients.

Value of CT-based radiomics in evaluating the response of bone metastases to systemic drug therapy in breast cancer patients.

This study aimed to investigate the value of nonenhanced computed tomography (CT)-based radiomics in determining disease progression in breast cancer patients with bone marrow metastases and to develop a model for assessing treatment efficacy. A total of 134 breast cancer patients with bone metastases were enrolled from three hospitals. Nonenhanced CT was performed after two cycles of drug treatment. The images were categorized into an invalid and a valid group according to disease progression status. The largest osteolytic lesions' maximum cross-sections in the CT images were selected as regions of interest (ROIs) for feature extraction. Variance threshold, SelectKBest, and least absolute shrinkage and selection operator (LASSO) were used to reduce feature dimensionality. K-nearest neighbor algorithm (KNN), support vector machine (SVM), extreme gradient boosting (XGBoost), random forest (RF), logistic regression (LR), and decision tree (DT) algorithms were trained to establish radiomics models. Receiver operating characteristic (ROC) curves were generated to evaluate the diagnostic performance of the models. The KNN classifier demonstrated the best performance compared to the random grouping method. In the validation group, the area under the ROC curve (AUC) was 0.810. In the cross-validation method, the RF classifier showed the best performance with an AUC of 0.84. Nonenhanced CT-based radiomics provides a promising method for evaluating the efficacy of systemic drug therapy in breast cancer patients with osteolytic bone metastases.

Effects of collaborative filtering‐based peer recommendation mechanism on in‐service teachers’ learning performance, knowledge construction, and social network during online training

AbstractBackgroundCollaborative learning has become a crucial approach to promoting online in‐service teacher training. Appropriate peer recommendation for group composition is the basis to ensure productive learning outcomes of collaborative learning. However, there is a lack of understanding of the impact of peer recommendation on in‐service teachers' online training.ObjectivesTherefore, based on the collaborative filtering approach, a peer recommendation mechanism for in‐service teachers was constructed in this study. We investigated the effects of the constructed mechanism on in‐service teachers' online learning performance, interactive knowledge construction behavioural patterns and social networks.MethodsIn this study, 82 in‐service teachers were recruited to participate in the study. Participants under the experimental condition (n = 41) were invited to apply collaborative filtering‐based peer recommendation mechanism for grouping, while participants under the control condition (n = 41) were invited to use random grouping method. Participants' interaction data were collected from online collaborative discussion activities in a 5‐week asynchronous online course. The pre‐post knowledge test, content analysis, lag sequential analysis and social network analysis were used to analyse the differences between groups.Results and ConclusionsThe following findings were revealed: (1) the experimental group performed better than the control group in terms of online learning performance; (2) interactive knowledge construction behavioural patterns generated in collaborative activities showed that the experimental group achieved deeper level of knowledge construction in collaboration than the control group; (3) social networks generated in collaborative activities showed that the experimental group had tighter interaction relationships than the control group. Therefore, the peer recommendation mechanism could be useful to improve peer recommendation for group composition and had positive effects on in‐service teachers' online training.ImplicationsThis study can shed light on the construction of peer recommendation mechanism in recommending appropriate peers for in‐service teachers and different learners in online collaborative learning.

Cloud-edge collaborated dust deposition degree monitoring for distributed photovoltaic systems

After installation, the long-term efficient operation dominates the profitability of photovoltaic (PV) generation systems. Unlike large-scale PV plants, distributed PV systems are relatively dispersed, and belong to different owners, whose main obstacle for maximizing the profit is the lack of professional maintenance. This paper therefore proposes a cloud-edge collaborated dust deposition degree monitoring scheme for distributed PV systems without employing additional equipment, sensors or meteorological data, which just assumes the operational and historical data of all distributed PV systems in the same area to give the guidance whether the distributed PV system needs cleaning. In implementation, temporal and interactive models are established based on the operation characteristics of distributed PV systems, whose overall classification accuracy could reach more than 98%. In addition, in order to improve the adaptivity of monitoring scheme, this paper proposes a data-based random grouping method, which avoids the model mismatch caused by the addition or withdrawal of PV arrays. Finally, experimental verifications are carried out to prove the effectiveness of the presented scheme.© 2017 Elsevier Inc. All rights reserved.

The Value of Combining Wu Ling San Plus and Minus with Repaglinide in the Treatment of Obese Type 2 Diabetes

Objective: To investigate the clinical value and practical effects of the treatment of obese type 2 diabetes mellitus patients with Wu Ling San plus and minus combined with Repaglinide. Methods: Twenty-two obese type 2 diabetic patients attending the outpatient clinic of Yixing Traditional Chinese Medicine Hospital from September 2020 to March 2022 were randomly selected as the subjects of this study, and all of them were divided into treatment group (n=11, Wu Ling San plus and minus + Repaglinide) and control group (n=11, single Repaglinide) according to the computerized random series grouping method. The clinical data and overall efficacy of the two groups were compared. Results: After treatment, the treatment group had better blood glucose, blood lipids and other basic indicators than the control group (P&lt;0.05); all Chinese medicine symptoms scores and complication rates of the treatment group were lower than those of the control group (P&lt;0.05). Conclusion: The treatment of obese type 2 diabetes mellitus patients with Wu Ling San plus reduction + Repaglinide has significant efficacy and high drug safety, and can stabilize many indicators of blood glucose and blood lipids, reduce the risk of complications and control their body weight, which can be promoted and used in the treatment of related clinical conditions.

A novel and alternative therapy for persistent allergic rhinitis via intranasal acupuncture: a randomized controlled trial

BackgroundAcupuncture is used to treat allergic rhinitis (AR) in traditional Chinese medicine, and the ST2 and ST36 acupoints are generally selected in clinical practice. We report a new intranasal acupuncture method at the Neiyingxiang (EX-HN9) and Biqiu points for the treatment of persistent AR (PAR). Here, the efficacy and safety of this method were evaluated.MethodsA total of 120 patients diagnosed with PAR were randomly allocated (2:1 ratio) to intranasal acupuncture or Western medicine groups, the basic principle of random grouping is SAS random grouping method. The applicator held a nasal endoscope and a 0.30 × 75 mm filiform needle in their left and right hands, respectively. When aiming at the Neiyingxiang or Biqiu point, the applicator quickly inserted the needle to a 20-mm depth as parallel as possible to the inferior turbinate or middle turbinate, without special reinforcing and reducing techniques (the needle remained for 20 min). The intranasal acupuncture groups received acupuncture treatment three times per week for 2 weeks. The Western medicine group was treated with budesonide nasal spray (two sprays/nostril, twice/day) and loratadine (one tablet/night) for 2 weeks. Visual analog scale (VAS) scores were the primary outcome. Quality of life, medication dosages and adverse events were secondary outcomes measured using the Rhinoconjunctivitis Quality-of-Life Questionnaire (RQLQ). Confidence assessments were performed to evaluate data from the treatment and follow-up periods.ResultsThe results were as follows: (1) VAS and RQLQ scores were significantly lower in the intranasal acupuncture group than in the Western medicine group on day 1 (i.e., first treatment) (P < 0.05; 95% CI − 13.1 to − 9.6 VAS points) (P < 0.05; 95% CI − 20.27 to − 12.28 RQLQ points). Overall symptoms (95% CI − 2.86 to − 1.86 points), nasal obstruction (95% CI − 6.33 to − 5.36 points), olfactory function (95% CI − 2.91 to − 1.75 points), sleep (95% CI − 5.05 to − 3.57 points), actual problems (95% CI − 2.03 to − 0.06 points), nasal symptoms (95% CI − 6.62 to − 4.5 points), and emotional problems (95% CI − 5.05 to − 3.5 points) were significantly improved. (2) VAS and RQLQ scores in the two groups were significantly improved at week 2; however, there were no significant group differences in the VAS (P > 0.05; 95% CI − 1.21 to − 1.38 points) and RQLQ (P > 0.05; 95% CI − 0.33 to − 3.46 points) scores. Olfactory function symptoms were significantly improved (95% CI − 1.58 to − 0.21 points). (3) During the follow-up period, there was a significant difference between the two groups (P < 0.05) with higher RQLQ and VAS scores in the intranasal acupuncture group than in the Western medicine group. VAS scores on rhinobyon symptoms, nasal itch, rhinorrhea and olfactory function and RQLQ scores for activities, non-nasal/eye symptoms, actual problems, nasal symptoms, and eye symptoms were significantly improved. (4) No adverse events were observed in either group during treatment.ConclusionsIntranasal acupuncture has good efficacy and safety in the treatment of PAR. Moreover, VAS and RQLQ scores were much lower in the intranasal acupuncture group than in the Western medicine group, and acupuncture had an immediate impact, especially for improving nasal congestion, olfactory function and sleep.

Clinical Study of 3DCRT Combined with SBRT in the Treatment of Patients with EGFR Mutation Oligometastatic Non-Small Cell Lung Cancer.

Lung cancer is one of the malignant tumors with the highest morbidity and mortality in my country and the world. Among them, non-small-cell lung cancer (NSCLC) accounts for about 80%. For patients who are diagnosed with NSCLC and have epidermal growth factor receptor, EGFR gene-sensitive mutations The treatment is particularly important. To investigate the efficacy and prognosis of 3DCRT combined with local SBRT in patients with EGFR mutation oligometastatic NSCLC. Eighty patients with EGFR mutation oligometastatic NSCLC were selected by random remainder grouping method. 3DCRT combined with SBRT is effective and safer in patients with EGFR-mutant oligometastatic NSCLC, and significantly improves the patient's immune and tumor marker levels. It has a certain reference value in the clinical treatment of EGFR-mutant oligometastatic NSCLC.

INFLUÊNCIA DO TREINO DO CORE ABDOMINAL SOBRE O CONTROLE DA ESTABILIDADE NOS JOGADORES DE TÊNIS DE MESA

ABSTRACT Introduction In recent years, there have been a number of reforms in table tennis, trends in technology development, and demands on the part of athletes to improve their competitive ability and prevent injuries. Objective Evaluate the effect of abdominal core strength training on ball control stability in table tennis players. Methods By random sampling and grouping method, the national top-level table tennis players were divided into an experimental group and a control group (17 boys in each group and seven girls in each group); the experiment lasted for one week, during which the athletes in the experimental group performed abdominal core strength training, while the athletes in the control group performed regular training. Results There was no significant difference in the longitudinal comparison of the control group before and after the experiment (P&gt;0.05), and there was a very significant difference in the horizontal comparison between the two groups after the experiment (P&lt;0.01). Conclusion Abdominal core strength training has a positive effect on improving the technical stability of table tennis players. Core strength can improve the athlete’s attack speed and recovery. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.

The diagnostic value and safety of modified needle aspiration biopsy for superficial lymphadenectasis.

To explore the safety and diagnostic value of modified needle aspiration biopsy for superficial enlarged lymph nodes. A total of 88 patients with unknown diagnosis of superficial lymphadenopathy in our hospital (Wuxi Fifth People's Hospital) from January 2018 to July 2021 were recruited and then divided into two groups using the simple random grouping method. The study group included 48 patients who were punctured via modified needle aspiration biopsy, while the control group included 40 patients who were punctured via core needle biopsy (CNB) and had a better clinical evaluation. A BARD® automatic biopsy gun with a 18 G needle was used to puncture any enlarged lymph nodes, and specimens were obtained for pathological examination. The diagnostic positive rate of the two puncture methods was then compared and the complications involved in the two methods were observed. The positive rate of definite pathological diagnosis was 79.2% (38/48) in the study group and 82.5% (33/40) in the control group. Both groups had similar diagnostic positive rates regarding tuberculosis and metastatic tumours in the lymph nodes (P > 0.05). Only slight bleeding was observed during the operations using the two puncture methods, with the bleeding rate of the study group 20.8% and that of the control group 15.0%, and the difference was not statistically significant (P > 0.05). No other complications were observed across both groups. Among the 48 patients with enlarged lymph nodes in the study group, there was no difference in the positive rate of diagnosis between enlarged lymph nodes larger than 20 mm and those smaller than 20 mm in the pathological, bacterial culture and cytology examinations (P > 0.05). The sensitivity, specificity, positive predictive values and negative prediction values of the improved lymph node lesions were 83.3%, 100%, 100% and 90.9%, respectively. The diagnostic efficacy and safety of modified needle aspiration biopsy in superficial swollen lymph nodes are equivalent to those of CNB, but the former is a more economical, simple and practical method for clinical settings and one that could be popularised in primary hospitals.

A random forest‐regression‐based inverse‐modeling evolutionary algorithm using uniform reference points

The model-based evolutionary algorithms are divided into three groups: estimation of distribution algorithms, inverse modeling, and surrogate modeling. Existing inverse modeling is mainly applied to solve multi-objective optimization problems and is not suitable for many-objective optimization problems. Some inversed-model techniques, such as the inversed-model of multi-objective evolutionary algorithm, constructed from the Pareto front (PF) to the Pareto solution on nondominated solutions using a random grouping method and Gaussian process, were introduced. However, some of the most efficient inverse models might be eliminated during this procedure. Also, there are challenges, such as the presence of many local PFs and developing poor solutions when the population has no evident regularity. This paper proposes inverse modeling using random forest regression and uniform reference points that map all nondominated solutions from the objective space to the decision space to solve many-objective optimization problems. The proposed algorithm is evaluated using the benchmark test suite for evolutionary algorithms. The results show an improvement in diversity and convergence performance (quality indicators).

Habitat radiomics analysis of pet/ct imaging in high-grade serous ovarian cancer: Application to Ki-67 status and progression-free survival.

Purpose: We aim to develop and validate PET/ CT image-based radiomics to determine the Ki-67 status of high-grade serous ovarian cancer (HGSOC), in which we use the metabolic subregion evolution to improve the prediction ability of the model. At the same time, the stratified effect of the radiomics model on the progression-free survival rate of ovarian cancer patients was illustrated. Materials and methods: We retrospectively reviewed 161 patients with HGSOC from April 2013 to January 2019. 18F-FDG PET/ CT images before treatment, pathological reports, and follow-up data were analyzed. A randomized grouping method was used to divide ovarian cancer patients into a training group and validation group. PET/ CT images were fused to extract radiomics features of the whole tumor region and radiomics features based on the Habitat method. The feature is dimensionality reduced, and meaningful features are screened to form a signature for predicting the Ki-67 status of ovarian cancer. Meanwhile, survival analysis was conducted to explore the hierarchical guidance significance of radiomics in the prognosis of patients with ovarian cancer. Results: Compared with texture features extracted from the whole tumor, the texture features generated by the Habitat method can better predict the Ki-67 state (p < 0.001). Radiomics based on Habitat can predict the Ki-67 expression accurately and has the potential to become a new marker instead of Ki-67. At the same time, the Habitat model can better stratify the prognosis (p < 0.05). Conclusion: We found a noninvasive imaging predictor that could guide the stratification of prognosis in ovarian cancer patients, which is related to the expression of Ki-67 in tumor tissues. This method is of great significance for the diagnosis and treatment of ovarian cancer.

Clinical Efficacy of Retroauricular Injection of Methylprednisolone Sodium Succinate in the Treatment of Sudden Deafness with Type 2 Diabetes.

Background The etiology of sudden deafness is still unclear. In recent years, people's life rhythm is getting faster and faster. Fatigue, environment, diet, psychology, and other factors have increased the morbidity rate of sudden deafness and improved the quality of life of patients. And work efficiency is greatly affected. Aims A study to investigate the clinical efficacy of postauricular injection of methylprednisolone sodium succinate in the treatment of sudden deafness with type 2 diabetes. Materials and Methods Sixty patients with sudden deafness who were treated in our hospital from January 2018 to October 2020 were selected as the subjects of this prospective study and divided into 30 cases each in the comparison group and the observation group according to the random number remainder grouping method. The comparison group was treated conventionally, and the observation group was treated with postauricular injection of methylprednisolone sodium succinate on the basis of the comparison group. Patients in the two groups were observed and compared on the 3rd, 6th, and 9th days after treatment with pure-tone hearing threshold checks and regular monitoring of blood glucose, blood rheology, and other indexes. Results On the 7th, 14th, and 30th days after treatment, the pure-tone audiometric thresholds of the two groups were gradually decreased, and the changes in the pure-tone audiometric thresholds in the observation group were greater than those in the control group. After lunch on the 6th day and after lunch on the 9th day, it was lower than that in the control group, and the difference was statistically significant (P < 0.05). 30 days after treatment, the blood viscosity, fibrin, and platelet aggregation rate of the observation group were significantly lower than those of the control group. After treatment, the clinical efficacy rate of the observation group was 96%, which was significantly higher than that of the control group, 80%, and the above differences were statistically significant (P < 0.05). Conclusion Treatment with postauricular injection of methylprednisolone sodium succinate has shown better therapeutic recovery in patients with sudden deafness, improved pure-tone hearing threshold, reduced risk of blood glucose elevation, and improved clinical outcomes for patients with sudden deafness, providing some reference for the treatment of patients with sudden deafness.

The Healing Effects of Piano Practice-Induced Hand Muscle Injury.

Background The muscles related to piano practice are mainly concentrated in the fingers and upper limbs, and the muscles related to other parts of the body are weak. Compared with other sports injuries, the injuries caused by piano practice are mainly chronic injuries caused by long-term strain of the upper limbs, and acute injuries rarely occur. The purpose of this study was to analyze the therapeutic effect of hand muscle injury caused by piano practice. Method A total of 60 patients with hand muscle injury caused by piano practice admitted to our hospital from January 2019 to June 2020 were selected. According to the number random grouping method, they were randomly divided into two groups. There were 30 patients in the observation group, including 20 males and 10 females, aged 24-53 (39.51 ± 7.01) years old, and the course of disease was 1-5 (3.24 ± 1.62) months. In the control group, there were 30 patients, including 18 males and 12 females, aged 24-56 (39.62 ± 7.17) years old, and the course of disease was 1.5-5 (3.14 ± 1.71) months. If the observation group experienced excessive pain, the group took ibuprofen sustained-release capsules. On weekdays, exercise your fingers 2-3 times per day. After the intervention, the wrist joint function score of the observation group was higher than that before the intervention. Results Before treatment, there was no significant difference in pain level scores between the two groups (P > 0.05). After treatment, the limb pain score in the observation group was lower than that in the control group. The effective rate of hand tendon rehabilitation in the observation group was 93.33%. The effective rate of hand tendon rehabilitation in the control group was 70.00%. The comparison results showed that there was statistical significance (P < 0.05). The score of the observation group was significantly higher than that of the control group, with statistically significant differences (P < 0.05). Conclusion Piano workouts can cause hand muscle difficulties, which can be alleviated by daily finger gymnastics. Daily finger exercises are simple and not limited by time and place. Piano practitioners can use the spare time of daily training and performance to exercise for a long time, so as to prevent or recover finger muscle damage caused by piano practice. It has the potential to help pianists avoid hand muscle injuries when practicing while also allowing music to reach its full potential.

Application of the Stratified Nursing Mode of the Prediction Model Constructed Based on Case System Data in the Nursing of Patients with Acute Renal Failure.

Objective To explore the application of the stratified nursing mode of the prediction model constructed based on case system data in the nursing of patients with acute renal failure (ARF). Methods A total of 84 patients with ARF confirmed in the hospital were enrolled between February 2020 and February 2022. According to the simple random grouping method, they were divided into an observation group and a control group, 42 cases in each group. The control group was given routine nursing while the observation group was given stratified nursing of the prediction model constructed based on case system data. All were nursed for 2 months. Results There was no significant difference in general data such as gender, age, body mass index (BMI), serum creatinine (Scr), hemoglobin (Hb), and albumin between the two groups (P > 0.05). Age >60 years, weight fluctuation >2 kg during dialysis, vascular blockage or infection, coronary heart disease, diabetes mellitus, chronic hepatopathy and stroke, bleeding tendency, and neuromuscular abnormalities were high-risk factors for ARF patients, hypertension, thyroid abnormalities, hyperlipidemia, persistent or repeated blood volume overload, and usage of antihypertensive drugs were moderate-risk factors for ARF patients, and nonpermeability dehydration was a low-risk factor of ARF patients. The scores of nursing satisfaction and treatment compliance in the observation group were significantly higher than those in the control group (P < 0.05). After 2 months of nursing, scores of SAS, SDS, and SPBS in both the groups were significantly decreased (P < 0.05), which were significantly lower in the observation group than those in the control group (P < 0.05). Conclusion The stratified nursing mode of the prediction model constructed based on case system data is conducive to timely and targeted nursing, with high patient satisfaction and cooperation, and a better psychological state.

Tertiary rehabilitation in acute ankle sprain caused by sports training.

An ankle sprain is a common joint sprain in sports injury, which is closely related to its physiological position and anatomical characteristics, and may progress into chronic ankle instability after improper early treatment or premature exercise. To analyze the tertiary rehabilitation effect of acute lateral ankle sprain caused by sports training. Ninety-six athletes with acute lateral ankle sprain diagnosed from January 2019 to June 2020 were included and divided into the control group and the rehabilitation group using the random number table grouping method, with 48 cases in each group. The two groups received standardized treatment, and the rehabilitation group additionally received tertiary rehabilitation. The American Orthopedic Foot and Ankle Society (AOFAS ) scores, degree of ankle swelling, pain, and re-injury rate were compared between the two groups. The AOFAS scores of the two groups increased after treatment (P< 0.05). The degree of swelling in both groups after treatment was improved (P< 0.05). The Visual Analogue Scale (VAS) scores in both groups declined two weeks after treatment, with lower results observed in the rehabilitation group The two groups showed similar results of the follow-up visit (P< 0.05). Rehabilitation exercise on acute lateral ankle sprain effectively relieves ankle swelling and pain.