Aims: This study aimed to evaluate cranial base measurements in individuals with different skeletal relationships (class I, II, and III) using Bjork-Jarabak analysis and compare them with existing research. Material and Method: Lateral cephalograms of 103 Sudanese participants (aged 18-22) were assessed, grouped by ANB angle. Results: Showed no significant differences between class I and II, or class I and III skeletal relationships. However, class II and III relationships exhibited significant differences in Articulare angle, Gonial angle, ramal height, and mandibular length (P<0.0001). Discrepancies in craniofacial morphology were observed between Sudanese and Bjork-Jarabak norms for Caucasian. Conclusion: Saddle angle, Bjork sum of angles, and cranial case showed no significant differences among skeletal classes, but significant differences in several measurements existed between class II and III relationships.